BTBD18 (BTB domain containing 18)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 643376
• Gene name: BTB domain containing 18
• Gene symbol: BTBD18
• Synonyms (NCBI Gene): -
• Chromosome: 11
• Chromosome location: 11q12.1

miRNA Show/Hide all (41)

miRTarBase ID	miRNA	Experiments	Reference
MIRT826361	hsa-miR-1276	CLIP-seq
MIRT826362	hsa-miR-1283	CLIP-seq
MIRT826363	hsa-miR-1321	CLIP-seq
MIRT826364	hsa-miR-3202	CLIP-seq
MIRT826365	hsa-miR-3649	CLIP-seq
MIRT826366	hsa-miR-4475	CLIP-seq
MIRT826367	hsa-miR-4476	CLIP-seq
MIRT826368	hsa-miR-4739	CLIP-seq
MIRT826369	hsa-miR-4756-5p	CLIP-seq
MIRT826370	hsa-miR-520d-5p	CLIP-seq
MIRT826371	hsa-miR-524-5p	CLIP-seq
MIRT1944361	hsa-miR-1228	CLIP-seq
MIRT1944362	hsa-miR-1254	CLIP-seq
MIRT1944363	hsa-miR-141	CLIP-seq
MIRT1944364	hsa-miR-200a	CLIP-seq
MIRT1944365	hsa-miR-2467-5p	CLIP-seq
MIRT1944366	hsa-miR-3116	CLIP-seq
MIRT1944367	hsa-miR-3162-5p	CLIP-seq
MIRT1944368	hsa-miR-3188	CLIP-seq
MIRT1944369	hsa-miR-377	CLIP-seq
MIRT1944370	hsa-miR-3975	CLIP-seq
MIRT1944371	hsa-miR-3977	CLIP-seq
MIRT1944372	hsa-miR-4303	CLIP-seq
MIRT1944373	hsa-miR-4649-3p	CLIP-seq
MIRT1944374	hsa-miR-485-5p	CLIP-seq
MIRT1944375	hsa-miR-661	CLIP-seq
MIRT1944361	hsa-miR-1228	CLIP-seq
MIRT1944362	hsa-miR-1254	CLIP-seq
MIRT1944363	hsa-miR-141	CLIP-seq
MIRT1944364	hsa-miR-200a	CLIP-seq
MIRT1944365	hsa-miR-2467-5p	CLIP-seq
MIRT1944366	hsa-miR-3116	CLIP-seq
MIRT1944367	hsa-miR-3162-5p	CLIP-seq
MIRT1944368	hsa-miR-3188	CLIP-seq
MIRT1944369	hsa-miR-377	CLIP-seq
MIRT1944370	hsa-miR-3975	CLIP-seq
MIRT1944371	hsa-miR-3977	CLIP-seq
MIRT1944372	hsa-miR-4303	CLIP-seq
MIRT1944373	hsa-miR-4649-3p	CLIP-seq
MIRT1944374	hsa-miR-485-5p	CLIP-seq
MIRT1944375	hsa-miR-661	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0007141	Process	Male meiosis I	IEA
GO:0007141	Process	Male meiosis I	ISS
GO:0007283	Process	Spermatogenesis	IEA
GO:0007283	Process	Spermatogenesis	ISS
GO:0010526	Process	Transposable element silencing	IEA
GO:0010526	Process	Transposable element silencing	ISS
GO:0030154	Process	Cell differentiation	IEA
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	IEA
GO:0140541	Process	PiRNA transcription	IEA
GO:0140541	Process	PiRNA transcription	ISS

Other IDs

• MIM: 621145
• HGNC: 37214
• e!Ensembl: ENSG00000233436

Protein

• UniProt ID: B2RXH4
• Protein name: BTB/POZ domain-containing protein 18
• Protein function: Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and gov
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	24 → 126	BTB/POZ domain	Domain

• Sequence:

  MCSPASPKILYRNPRFLRLAFLQLHHQQQSDVFCDVLLQAEGEAVPAHCCILSACSPFFT
  ERLERERPAQGGKVVLELGGLKISTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSEL
  ESLQLEGGKLVKAPQGRRLNRECLQPTSAAPISARVVTPSHHPHTPLPTNQTPCPLGAIR
  LKSLGKEEGPQENNRQNADNLSGTLLLKRKARACPTPQEKNSSPSSHSQEPRENKNDTAL
  DPTVLSPPSLYPSVDKHLLPRKIRLSRSKPSPGICTSKPSSILSGSSSVPATPGRRLWRQ
  RSVNKETPEDKPKPGRASPLQSTPNPSGLGKTGGSRKRSPEVRAPNSDSAEEGQVGRVKL
  RKIVNGTCWEVVQETPLKNTQDSPQIPDPGGDFQEPSGTQPFSSNEQEMSPTRTELCQDS
  PMCTKLQDILVSASHSPDHPVVKSEFESSPELVEKEPMLAIDCREPYAFDTALLEQPCEA
  EEYRITSAAATSELEEILDFMLCGSDIEPPIGSLESPGAEGCRTPTYHLTETGKNWIEGE
  EWCLPDMELWPRELTELEKEPAGENRGPTELLSPLVMPSEVSEVLSVGGRWTPDLEITSS
  QPLDGQEDKLLHVSSLDTPQRSYGDLSPPCSNWVETGLEVSLTTDELLYPSPKAGKEVSG
  HSELLGSLPASSEEEEIDVVDWTAEGRLVPTTVPSVWPDPSSESETEVDILT

• Sequence length: 712

Related Genes

No strongly related genes found yet for BTBD18.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to BTBD18.