BROX (BRO1 domain and CAAX motif containing)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 148362
• Gene name: BRO1 domain and CAAX motif containing
• Gene symbol: BROX
• Synonyms (NCBI Gene): C1orf58
• Chromosome: 1
• Chromosome location: 1q41

miRNA Show/Hide all (293)

miRTarBase ID	miRNA	Experiments	Reference
MIRT669865	hsa-miR-4318	HITS-CLIP	19536157
MIRT669864	hsa-miR-5693	HITS-CLIP	19536157
MIRT669863	hsa-miR-6499-3p	HITS-CLIP	19536157
MIRT669862	hsa-miR-6076	HITS-CLIP	19536157
MIRT669861	hsa-miR-6797-3p	HITS-CLIP	19536157
MIRT669860	hsa-miR-3135b	HITS-CLIP	19536157
MIRT669859	hsa-miR-504-3p	HITS-CLIP	19536157
MIRT669858	hsa-miR-122-5p	HITS-CLIP	19536157
MIRT669857	hsa-miR-3622b-5p	HITS-CLIP	19536157
MIRT669856	hsa-miR-3652	HITS-CLIP	19536157
MIRT669855	hsa-miR-4430	HITS-CLIP	19536157
MIRT669854	hsa-miR-143-5p	HITS-CLIP	19536157
MIRT669853	hsa-miR-203a-5p	HITS-CLIP	19536157
MIRT669852	hsa-miR-1273g-5p	HITS-CLIP	19536157
MIRT669851	hsa-miR-943	HITS-CLIP	19536157
MIRT669850	hsa-miR-5698	HITS-CLIP	19536157
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT642843	hsa-miR-5690	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT624538	hsa-miR-4459	HITS-CLIP	23824327
MIRT624537	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT679698	hsa-miR-7977	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT669865	hsa-miR-4318	HITS-CLIP	23824327
MIRT669864	hsa-miR-5693	HITS-CLIP	23824327
MIRT669863	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT669862	hsa-miR-6076	HITS-CLIP	23824327
MIRT669861	hsa-miR-6797-3p	HITS-CLIP	23824327
MIRT669860	hsa-miR-3135b	HITS-CLIP	23824327
MIRT669859	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT669858	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT669857	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT669856	hsa-miR-3652	HITS-CLIP	23824327
MIRT669855	hsa-miR-4430	HITS-CLIP	23824327
MIRT669854	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT669853	hsa-miR-203a-5p	HITS-CLIP	23824327
MIRT669852	hsa-miR-1273g-5p	HITS-CLIP	23824327
MIRT669851	hsa-miR-943	HITS-CLIP	23824327
MIRT669850	hsa-miR-5698	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT642843	hsa-miR-5690	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT624538	hsa-miR-4459	HITS-CLIP	23824327
MIRT624537	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT642843	hsa-miR-5690	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT624538	hsa-miR-4459	HITS-CLIP	23824327
MIRT624537	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT669865	hsa-miR-4318	HITS-CLIP	19536157
MIRT669864	hsa-miR-5693	HITS-CLIP	19536157
MIRT669863	hsa-miR-6499-3p	HITS-CLIP	19536157
MIRT669862	hsa-miR-6076	HITS-CLIP	19536157
MIRT669861	hsa-miR-6797-3p	HITS-CLIP	19536157
MIRT669860	hsa-miR-3135b	HITS-CLIP	19536157
MIRT669859	hsa-miR-504-3p	HITS-CLIP	19536157
MIRT669858	hsa-miR-122-5p	HITS-CLIP	19536157
MIRT669857	hsa-miR-3622b-5p	HITS-CLIP	19536157
MIRT669856	hsa-miR-3652	HITS-CLIP	19536157
MIRT669855	hsa-miR-4430	HITS-CLIP	19536157
MIRT669854	hsa-miR-143-5p	HITS-CLIP	19536157
MIRT669853	hsa-miR-203a-5p	HITS-CLIP	19536157
MIRT669852	hsa-miR-1273g-5p	HITS-CLIP	19536157
MIRT669851	hsa-miR-943	HITS-CLIP	19536157
MIRT669850	hsa-miR-5698	HITS-CLIP	19536157
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT642843	hsa-miR-5690	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT624538	hsa-miR-4459	HITS-CLIP	23824327
MIRT624537	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT679698	hsa-miR-7977	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT669865	hsa-miR-4318	HITS-CLIP	23824327
MIRT669864	hsa-miR-5693	HITS-CLIP	23824327
MIRT669863	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT669862	hsa-miR-6076	HITS-CLIP	23824327
MIRT669861	hsa-miR-6797-3p	HITS-CLIP	23824327
MIRT669860	hsa-miR-3135b	HITS-CLIP	23824327
MIRT669859	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT669858	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT669857	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT669856	hsa-miR-3652	HITS-CLIP	23824327
MIRT669855	hsa-miR-4430	HITS-CLIP	23824327
MIRT669854	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT669853	hsa-miR-203a-5p	HITS-CLIP	23824327
MIRT669852	hsa-miR-1273g-5p	HITS-CLIP	23824327
MIRT669851	hsa-miR-943	HITS-CLIP	23824327
MIRT669850	hsa-miR-5698	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT642843	hsa-miR-5690	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT624538	hsa-miR-4459	HITS-CLIP	23824327
MIRT624537	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT642843	hsa-miR-5690	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT624539	hsa-miR-506-5p	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT624538	hsa-miR-4459	HITS-CLIP	23824327
MIRT624537	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT615241	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT615240	hsa-miR-4760-3p	HITS-CLIP	23824327
MIRT615239	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT615238	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT615237	hsa-miR-940	HITS-CLIP	23824327
MIRT615236	hsa-miR-3929	HITS-CLIP	23824327
MIRT615235	hsa-miR-4419b	HITS-CLIP	23824327
MIRT615234	hsa-miR-4478	HITS-CLIP	23824327
MIRT615233	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT615232	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT615231	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT615230	hsa-miR-1827	HITS-CLIP	23824327
MIRT615229	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT615228	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT615227	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT615226	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT615225	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT615224	hsa-miR-665	HITS-CLIP	23824327
MIRT825148	hsa-miR-130a	CLIP-seq
MIRT825149	hsa-miR-130b	CLIP-seq
MIRT825150	hsa-miR-301a	CLIP-seq
MIRT825151	hsa-miR-301b	CLIP-seq
MIRT825152	hsa-miR-302a	CLIP-seq
MIRT825153	hsa-miR-302b	CLIP-seq
MIRT825154	hsa-miR-302c	CLIP-seq
MIRT825155	hsa-miR-302d	CLIP-seq
MIRT825156	hsa-miR-302e	CLIP-seq
MIRT825157	hsa-miR-3666	CLIP-seq
MIRT825158	hsa-miR-372	CLIP-seq
MIRT825159	hsa-miR-373	CLIP-seq
MIRT825160	hsa-miR-382	CLIP-seq
MIRT825161	hsa-miR-4263	CLIP-seq
MIRT825162	hsa-miR-4295	CLIP-seq
MIRT825163	hsa-miR-454	CLIP-seq
MIRT825164	hsa-miR-519a	CLIP-seq
MIRT825165	hsa-miR-519b-3p	CLIP-seq
MIRT825166	hsa-miR-519c-3p	CLIP-seq
MIRT825167	hsa-miR-520a-3p	CLIP-seq
MIRT825168	hsa-miR-520b	CLIP-seq
MIRT825169	hsa-miR-520c-3p	CLIP-seq
MIRT825170	hsa-miR-520d-3p	CLIP-seq
MIRT825171	hsa-miR-520e	CLIP-seq
MIRT825172	hsa-miR-539	CLIP-seq

Gene ontology (GO) Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22162750, 22484091, 28514442, 33961781, 34818527
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IDA	34818527
GO:0007084	Process	Mitotic nuclear membrane reassembly	IMP	34818527
GO:0016020	Component	Membrane	IEA
GO:0031965	Component	Nuclear membrane	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 23533145

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5VW32
• Protein name: BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein)
• Protein function: Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured
• PDB: 3R9M , 3ULY , 3UM0 , 3UM1 , 3UM2 , 3UM3 , 3ZXP
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03097	BRO1	27 → 374	BRO1-like domain	Domain

• Sequence:

  MTHWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDLSCNPEMMKNA
  ADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVAL
  WYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHLPKLITPAEKGRDLESRLI
  EAYVIQCQAEAQEVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRK
  YLHLKMCFYTAYAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPT
  VKPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKIPTEAPQLELKANYGLVEPIPFEFPP
  TSVQWTPETLAAFDLTKRPKDDSTKPKPEEEVKPVKEPDIKPQKDTGCYIS

• Sequence length: 411

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (9)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

No strongly related genes found yet for BROX.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to BROX.