BRIX1 (biogenesis of ribosomes BRX1)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 55299
• Gene name: Biogenesis of ribosomes BRX1
• Gene symbol: BRIX1
• Synonyms (NCBI Gene): BRIX, BXDC2
• Chromosome: 5
• Chromosome location: 5p13.2

miRNA Show/Hide all (219)

miRTarBase ID	miRNA	Experiments	Reference
MIRT684824	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT684823	hsa-miR-6753-5p	HITS-CLIP	23313552
MIRT647078	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT684822	hsa-miR-1321	HITS-CLIP	23313552
MIRT684821	hsa-miR-4739	HITS-CLIP	23313552
MIRT684820	hsa-miR-4756-5p	HITS-CLIP	23313552
MIRT684819	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT684818	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT684817	hsa-miR-4270	HITS-CLIP	23313552
MIRT684816	hsa-miR-4441	HITS-CLIP	23313552
MIRT684815	hsa-miR-6754-5p	HITS-CLIP	23313552
MIRT684814	hsa-miR-7113-5p	HITS-CLIP	23313552
MIRT684813	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT647068	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT684812	hsa-miR-3689d	HITS-CLIP	23313552
MIRT684811	hsa-miR-6851-5p	HITS-CLIP	23313552
MIRT684810	hsa-miR-6880-5p	HITS-CLIP	23313552
MIRT684809	hsa-miR-7847-3p	HITS-CLIP	23313552
MIRT684808	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT684807	hsa-miR-665	HITS-CLIP	23313552
MIRT647079	hsa-miR-4661-3p	HITS-CLIP	23824327
MIRT647078	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT647077	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT647076	hsa-miR-940	HITS-CLIP	23824327
MIRT647075	hsa-miR-188-5p	HITS-CLIP	23824327
MIRT647073	hsa-miR-6866-3p	HITS-CLIP	23824327
MIRT647074	hsa-miR-4690-3p	HITS-CLIP	23824327
MIRT647072	hsa-miR-5685	HITS-CLIP	23824327
MIRT647071	hsa-miR-4459	HITS-CLIP	23824327
MIRT647070	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT647069	hsa-miR-1827	HITS-CLIP	23824327
MIRT647068	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT647067	hsa-miR-6894-5p	HITS-CLIP	23824327
MIRT647066	hsa-miR-3157-5p	HITS-CLIP	23824327
MIRT215642	hsa-miR-548n	PAR-CLIP	21572407
MIRT549147	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT549146	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT096497	hsa-miR-548l	PAR-CLIP	21572407
MIRT313502	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT096512	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT096510	hsa-miR-4643	PAR-CLIP	21572407
MIRT549145	hsa-miR-6863	PAR-CLIP	21572407
MIRT215641	hsa-miR-577	PAR-CLIP	21572407
MIRT549144	hsa-miR-4699-3p	PAR-CLIP	21572407
MIRT096503	hsa-miR-3941	PAR-CLIP	21572407
MIRT096511	hsa-miR-4672	PAR-CLIP	21572407
MIRT096500	hsa-miR-466	PAR-CLIP	21572407
MIRT538892	hsa-miR-512-5p	PAR-CLIP	22012620
MIRT538891	hsa-miR-510-5p	PAR-CLIP	22012620
MIRT538890	hsa-miR-3124-3p	PAR-CLIP	22012620
MIRT538889	hsa-miR-627-3p	PAR-CLIP	22012620
MIRT538888	hsa-miR-1468-5p	PAR-CLIP	22012620
MIRT096492	hsa-miR-548a-5p	PAR-CLIP	23446348
MIRT096505	hsa-miR-548ab	PAR-CLIP	23446348
MIRT096506	hsa-miR-548ad-5p	PAR-CLIP	23446348
MIRT096507	hsa-miR-548ae-5p	PAR-CLIP	23446348
MIRT096508	hsa-miR-548ak	PAR-CLIP	23446348
MIRT096509	hsa-miR-548am-5p	PAR-CLIP	23446348
MIRT096513	hsa-miR-548ap-5p	PAR-CLIP	23446348
MIRT096514	hsa-miR-548aq-5p	PAR-CLIP	23446348
MIRT096515	hsa-miR-548ar-5p	PAR-CLIP	23446348
MIRT096516	hsa-miR-548as-5p	PAR-CLIP	23446348
MIRT096517	hsa-miR-548au-5p	PAR-CLIP	23446348
MIRT096520	hsa-miR-548ay-5p	PAR-CLIP	23446348
MIRT096491	hsa-miR-548b-5p	PAR-CLIP	23446348
MIRT096522	hsa-miR-548bb-5p	PAR-CLIP	23446348
MIRT096493	hsa-miR-548c-5p	PAR-CLIP	23446348
MIRT096494	hsa-miR-548d-5p	PAR-CLIP	23446348
MIRT096498	hsa-miR-548h-5p	PAR-CLIP	23446348
MIRT096499	hsa-miR-548i	PAR-CLIP	23446348
MIRT096495	hsa-miR-548j-5p	PAR-CLIP	23446348
MIRT096504	hsa-miR-548o-5p	PAR-CLIP	23446348
MIRT096501	hsa-miR-548w	PAR-CLIP	23446348
MIRT096502	hsa-miR-548y	PAR-CLIP	23446348
MIRT096490	hsa-miR-559	PAR-CLIP	23446348
MIRT096519	hsa-miR-548av-5p	PAR-CLIP	23446348
MIRT096496	hsa-miR-548k	PAR-CLIP	23446348
MIRT096521	hsa-miR-8054	PAR-CLIP	23446348
MIRT096497	hsa-miR-548l	PAR-CLIP	23446348
MIRT524722	hsa-miR-7-1-3p	PAR-CLIP	23446348
MIRT524721	hsa-miR-7-2-3p	PAR-CLIP	23446348
MIRT096512	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT096510	hsa-miR-4643	PAR-CLIP	23446348
MIRT096488	hsa-miR-142-5p	PAR-CLIP	23446348
MIRT096518	hsa-miR-5590-3p	PAR-CLIP	23446348
MIRT096503	hsa-miR-3941	PAR-CLIP	23446348
MIRT096511	hsa-miR-4672	PAR-CLIP	23446348
MIRT096500	hsa-miR-466	PAR-CLIP	23446348
MIRT096489	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT524720	hsa-miR-5585-3p	PAR-CLIP	23446348
MIRT513046	hsa-miR-6887-3p	PAR-CLIP	23446348
MIRT513045	hsa-miR-6795-3p	PAR-CLIP	23446348
MIRT513044	hsa-miR-4667-3p	PAR-CLIP	23446348
MIRT513043	hsa-miR-660-3p	PAR-CLIP	23446348
MIRT513042	hsa-miR-4324	PAR-CLIP	23446348
MIRT513041	hsa-miR-544b	PAR-CLIP	23446348
MIRT513039	hsa-miR-3653-5p	PAR-CLIP	23446348
MIRT513040	hsa-miR-4251	PAR-CLIP	23446348
MIRT513038	hsa-miR-6878-5p	PAR-CLIP	23446348
MIRT513037	hsa-miR-3175	PAR-CLIP	23446348
MIRT513036	hsa-miR-6826-3p	PAR-CLIP	23446348
MIRT513035	hsa-miR-1200	PAR-CLIP	23446348
MIRT513034	hsa-miR-3679-3p	PAR-CLIP	23446348
MIRT513033	hsa-miR-6734-5p	PAR-CLIP	23446348
MIRT684824	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT684823	hsa-miR-6753-5p	HITS-CLIP	23313552
MIRT647078	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT684822	hsa-miR-1321	HITS-CLIP	23313552
MIRT684821	hsa-miR-4739	HITS-CLIP	23313552
MIRT684820	hsa-miR-4756-5p	HITS-CLIP	23313552
MIRT684819	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT684818	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT684817	hsa-miR-4270	HITS-CLIP	23313552
MIRT684816	hsa-miR-4441	HITS-CLIP	23313552
MIRT684815	hsa-miR-6754-5p	HITS-CLIP	23313552
MIRT684814	hsa-miR-7113-5p	HITS-CLIP	23313552
MIRT684813	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT647068	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT684812	hsa-miR-3689d	HITS-CLIP	23313552
MIRT684811	hsa-miR-6851-5p	HITS-CLIP	23313552
MIRT684810	hsa-miR-6880-5p	HITS-CLIP	23313552
MIRT684809	hsa-miR-7847-3p	HITS-CLIP	23313552
MIRT684808	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT684807	hsa-miR-665	HITS-CLIP	23313552
MIRT647079	hsa-miR-4661-3p	HITS-CLIP	23824327
MIRT647078	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT647077	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT647076	hsa-miR-940	HITS-CLIP	23824327
MIRT647075	hsa-miR-188-5p	HITS-CLIP	23824327
MIRT647073	hsa-miR-6866-3p	HITS-CLIP	23824327
MIRT647074	hsa-miR-4690-3p	HITS-CLIP	23824327
MIRT647072	hsa-miR-5685	HITS-CLIP	23824327
MIRT647071	hsa-miR-4459	HITS-CLIP	23824327
MIRT647070	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT647069	hsa-miR-1827	HITS-CLIP	23824327
MIRT647068	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT647067	hsa-miR-6894-5p	HITS-CLIP	23824327
MIRT647066	hsa-miR-3157-5p	HITS-CLIP	23824327
MIRT215642	hsa-miR-548n	PAR-CLIP	21572407
MIRT549147	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT549146	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT096497	hsa-miR-548l	PAR-CLIP	21572407
MIRT313502	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT096512	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT096510	hsa-miR-4643	PAR-CLIP	21572407
MIRT549145	hsa-miR-6863	PAR-CLIP	21572407
MIRT215641	hsa-miR-577	PAR-CLIP	21572407
MIRT549144	hsa-miR-4699-3p	PAR-CLIP	21572407
MIRT096503	hsa-miR-3941	PAR-CLIP	21572407
MIRT096511	hsa-miR-4672	PAR-CLIP	21572407
MIRT096500	hsa-miR-466	PAR-CLIP	21572407
MIRT538892	hsa-miR-512-5p	PAR-CLIP	22012620
MIRT538891	hsa-miR-510-5p	PAR-CLIP	22012620
MIRT538890	hsa-miR-3124-3p	PAR-CLIP	22012620
MIRT538889	hsa-miR-627-3p	PAR-CLIP	22012620
MIRT538888	hsa-miR-1468-5p	PAR-CLIP	22012620
MIRT096492	hsa-miR-548a-5p	PAR-CLIP	23446348
MIRT096505	hsa-miR-548ab	PAR-CLIP	23446348
MIRT096506	hsa-miR-548ad-5p	PAR-CLIP	23446348
MIRT096507	hsa-miR-548ae-5p	PAR-CLIP	23446348
MIRT096508	hsa-miR-548ak	PAR-CLIP	23446348
MIRT096509	hsa-miR-548am-5p	PAR-CLIP	23446348
MIRT096513	hsa-miR-548ap-5p	PAR-CLIP	23446348
MIRT096514	hsa-miR-548aq-5p	PAR-CLIP	23446348
MIRT096515	hsa-miR-548ar-5p	PAR-CLIP	23446348
MIRT096516	hsa-miR-548as-5p	PAR-CLIP	23446348
MIRT096517	hsa-miR-548au-5p	PAR-CLIP	23446348
MIRT096520	hsa-miR-548ay-5p	PAR-CLIP	23446348
MIRT096491	hsa-miR-548b-5p	PAR-CLIP	23446348
MIRT096522	hsa-miR-548bb-5p	PAR-CLIP	23446348
MIRT096493	hsa-miR-548c-5p	PAR-CLIP	23446348
MIRT096494	hsa-miR-548d-5p	PAR-CLIP	23446348
MIRT096498	hsa-miR-548h-5p	PAR-CLIP	23446348
MIRT096499	hsa-miR-548i	PAR-CLIP	23446348
MIRT096495	hsa-miR-548j-5p	PAR-CLIP	23446348
MIRT096504	hsa-miR-548o-5p	PAR-CLIP	23446348
MIRT096501	hsa-miR-548w	PAR-CLIP	23446348
MIRT096502	hsa-miR-548y	PAR-CLIP	23446348
MIRT096490	hsa-miR-559	PAR-CLIP	23446348
MIRT096519	hsa-miR-548av-5p	PAR-CLIP	23446348
MIRT096496	hsa-miR-548k	PAR-CLIP	23446348
MIRT096521	hsa-miR-8054	PAR-CLIP	23446348
MIRT096497	hsa-miR-548l	PAR-CLIP	23446348
MIRT524722	hsa-miR-7-1-3p	PAR-CLIP	23446348
MIRT524721	hsa-miR-7-2-3p	PAR-CLIP	23446348
MIRT096512	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT096510	hsa-miR-4643	PAR-CLIP	23446348
MIRT096488	hsa-miR-142-5p	PAR-CLIP	23446348
MIRT096518	hsa-miR-5590-3p	PAR-CLIP	23446348
MIRT096503	hsa-miR-3941	PAR-CLIP	23446348
MIRT096511	hsa-miR-4672	PAR-CLIP	23446348
MIRT096500	hsa-miR-466	PAR-CLIP	23446348
MIRT096489	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT524720	hsa-miR-5585-3p	PAR-CLIP	23446348
MIRT513046	hsa-miR-6887-3p	PAR-CLIP	23446348
MIRT513045	hsa-miR-6795-3p	PAR-CLIP	23446348
MIRT513044	hsa-miR-4667-3p	PAR-CLIP	23446348
MIRT513043	hsa-miR-660-3p	PAR-CLIP	23446348
MIRT513042	hsa-miR-4324	PAR-CLIP	23446348
MIRT513041	hsa-miR-544b	PAR-CLIP	23446348
MIRT513039	hsa-miR-3653-5p	PAR-CLIP	23446348
MIRT513040	hsa-miR-4251	PAR-CLIP	23446348
MIRT513038	hsa-miR-6878-5p	PAR-CLIP	23446348
MIRT513037	hsa-miR-3175	PAR-CLIP	23446348
MIRT513036	hsa-miR-6826-3p	PAR-CLIP	23446348
MIRT513035	hsa-miR-1200	PAR-CLIP	23446348
MIRT513034	hsa-miR-3679-3p	PAR-CLIP	23446348
MIRT513033	hsa-miR-6734-5p	PAR-CLIP	23446348
MIRT824915	hsa-miR-3156-5p	CLIP-seq
MIRT824916	hsa-miR-34b	CLIP-seq
MIRT824917	hsa-miR-3658	CLIP-seq
MIRT824918	hsa-miR-4420	CLIP-seq
MIRT824919	hsa-miR-4775	CLIP-seq
MIRT824920	hsa-miR-548t	CLIP-seq
MIRT824921	hsa-miR-578	CLIP-seq
MIRT824922	hsa-miR-590-3p	CLIP-seq
MIRT824923	hsa-miR-643	CLIP-seq
MIRT824915	hsa-miR-3156-5p	CLIP-seq
MIRT824917	hsa-miR-3658	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000027	Process	Ribosomal large subunit assembly	IBA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IBA
GO:0005515	Function	Protein binding	IPI	26496610, 28514442, 30021884, 32296183, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IDA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0005730	Component	Nucleolus	IEA
GO:0006364	Process	RRNA processing	IEA
GO:0019843	Function	RRNA binding	IEA
GO:0042254	Process	Ribosome biogenesis	IEA

Other IDs

• MIM: 618466
• HGNC: 24170
• e!Ensembl: ENSG00000113460

Protein

• UniProt ID: Q8TDN6
• Protein name: Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
• Protein function: Required for biogenesis of the 60S ribosomal subunit.
• PDB: 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04427	Brix	67 → 242	Brix domain	Domain

• Sequence:

  MAATKRKRRGGFAVQAKKPKRNEIDAEPPAKRHATAEEVEEEERDRIPGPVCKGKWKNKE
  RILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEA
  KKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYAL
  LKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNL
  IKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYREKQQVKDVQKLRKKEPKTLLPH
  DPTADVFVTPAEEKPIEIQWVKPEPKVDLKARKKRIYKRQRKMKQRMDSGKTK

• Sequence length: 353

Related Genes

No strongly related genes found yet for BRIX1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to BRIX1.