BOLA1 (bolA family member 1)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 51027
• Gene name: BolA family member 1
• Gene symbol: BOLA1
• Synonyms (NCBI Gene): CGI-143
• Chromosome: 1
• Chromosome location: 1q21.2

miRNA Show/Hide all (67)

miRTarBase ID	miRNA	Experiments	Reference
MIRT639412	hsa-miR-127-3p	HITS-CLIP	23824327
MIRT639411	hsa-miR-7152-3p	HITS-CLIP	23824327
MIRT639412	hsa-miR-127-3p	HITS-CLIP	23824327
MIRT639411	hsa-miR-7152-3p	HITS-CLIP	23824327
MIRT639412	hsa-miR-127-3p	HITS-CLIP	23824327
MIRT639411	hsa-miR-7152-3p	HITS-CLIP	23824327
MIRT639412	hsa-miR-127-3p	HITS-CLIP	23824327
MIRT639411	hsa-miR-7152-3p	HITS-CLIP	23824327
MIRT823705	hsa-miR-188-5p	CLIP-seq
MIRT823706	hsa-miR-1915	CLIP-seq
MIRT823707	hsa-miR-193a-5p	CLIP-seq
MIRT823708	hsa-miR-3143	CLIP-seq
MIRT823709	hsa-miR-3159	CLIP-seq
MIRT823710	hsa-miR-3675-5p	CLIP-seq
MIRT823711	hsa-miR-4299	CLIP-seq
MIRT823712	hsa-miR-4445	CLIP-seq
MIRT823713	hsa-miR-4456	CLIP-seq
MIRT823714	hsa-miR-4778-5p	CLIP-seq
MIRT823715	hsa-miR-4802-3p	CLIP-seq
MIRT823716	hsa-miR-548q	CLIP-seq
MIRT823705	hsa-miR-188-5p	CLIP-seq
MIRT823706	hsa-miR-1915	CLIP-seq
MIRT823707	hsa-miR-193a-5p	CLIP-seq
MIRT1920286	hsa-miR-520d-5p	CLIP-seq
MIRT1920287	hsa-miR-524-5p	CLIP-seq
MIRT823705	hsa-miR-188-5p	CLIP-seq
MIRT823706	hsa-miR-1915	CLIP-seq
MIRT823707	hsa-miR-193a-5p	CLIP-seq
MIRT1920286	hsa-miR-520d-5p	CLIP-seq
MIRT1920287	hsa-miR-524-5p	CLIP-seq
MIRT823708	hsa-miR-3143	CLIP-seq
MIRT823711	hsa-miR-4299	CLIP-seq
MIRT823712	hsa-miR-4445	CLIP-seq
MIRT823713	hsa-miR-4456	CLIP-seq
MIRT1943543	hsa-miR-4493	CLIP-seq
MIRT1943544	hsa-miR-4747-5p	CLIP-seq
MIRT823714	hsa-miR-4778-5p	CLIP-seq
MIRT823715	hsa-miR-4802-3p	CLIP-seq
MIRT823716	hsa-miR-548q	CLIP-seq
MIRT1943545	hsa-miR-938	CLIP-seq
MIRT2384851	hsa-miR-1269	CLIP-seq
MIRT2384852	hsa-miR-1269b	CLIP-seq
MIRT2384853	hsa-miR-1288	CLIP-seq
MIRT2384854	hsa-miR-3690	CLIP-seq
MIRT2384855	hsa-miR-378	CLIP-seq
MIRT2384856	hsa-miR-378b	CLIP-seq
MIRT2384857	hsa-miR-378c	CLIP-seq
MIRT2384858	hsa-miR-378d	CLIP-seq
MIRT2384859	hsa-miR-378e	CLIP-seq
MIRT2384860	hsa-miR-378f	CLIP-seq
MIRT2384861	hsa-miR-378h	CLIP-seq
MIRT2384862	hsa-miR-378i	CLIP-seq
MIRT2384863	hsa-miR-422a	CLIP-seq
MIRT2384864	hsa-miR-4254	CLIP-seq
MIRT2384865	hsa-miR-4515	CLIP-seq
MIRT2384866	hsa-miR-4740-5p	CLIP-seq
MIRT1920286	hsa-miR-520d-5p	CLIP-seq
MIRT1920287	hsa-miR-524-5p	CLIP-seq
MIRT2485866	hsa-miR-192	CLIP-seq
MIRT2485867	hsa-miR-215	CLIP-seq
MIRT2485868	hsa-miR-3661	CLIP-seq
MIRT2485869	hsa-miR-3924	CLIP-seq
MIRT2485870	hsa-miR-4659a-3p	CLIP-seq
MIRT2485871	hsa-miR-4659b-3p	CLIP-seq
MIRT2485872	hsa-miR-4753-3p	CLIP-seq
MIRT2485873	hsa-miR-631	CLIP-seq
MIRT2485874	hsa-miR-942	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 27532772, 28514442, 29892012, 31515488, 32296183, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	22746225
GO:0005739	Component	Mitochondrion	IEA
GO:0005739	Component	Mitochondrion	NAS	22746225
GO:0006879	Process	Intracellular iron ion homeostasis	NAS	27519415
GO:0016226	Process	Iron-sulfur cluster assembly	NAS	27532772
GO:0045454	Process	Cell redox homeostasis	NAS	27532772
GO:1990229	Component	Iron-sulfur cluster assembly complex	IEA
GO:1990229	Component	Iron-sulfur cluster assembly complex	IPI	27532772

Other IDs

• MIM: 613181
• HGNC: 24263
• e!Ensembl: ENSG00000178096

Protein

• UniProt ID: Q9Y3E2
• Protein name: BolA-like protein 1 (hBolA)
• Protein function: Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5 (PubMed:27532772).
• PDB: 5LCI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01722	BolA	40 → 113	BolA-like protein	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:18548201}.
• Sequence:

  MLSGRLVLGLVSMAGRVCLCQGSAGSGAIGPVEAAIRTKLEEALSPEVLELRNESGGHAV
  PPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALAEELGGPVHALAIQARTPAQWRENSQL
  DTSPPCLGGNKKTLGTP

• Sequence length: 137

Related Genes

No strongly related genes found yet for BOLA1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to BOLA1.