BCL7B (BAF chromatin remodeling complex subunit BCL7B)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9275 |
| Gene name | BAF chromatin remodeling complex subunit BCL7B |
| Gene symbol | BCL7B |
| Synonyms (NCBI Gene) |
SMARCJ2
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| Chromosome | 7 |
| Chromosome location | 7q11.23 |
| Summary | This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene kn |
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miRNA
miRNA information provided by mirtarbase database.
586
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9BQE9 | ||||||||||
| Protein name | B-cell CLL/lymphoma 7 protein family member B (allergen Hom s 3) | ||||||||||
| Protein function | Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1 (PubMed:25569233). Involved in cell cycle progression, maintenance of the nuclear struc | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:9860302, ECO:0000269|PubMed:9931421}. | ||||||||||
| Sequence |
MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS |
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| Sequence length | 202 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with BCL7B across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to BCL7B (see Related Genes above), that are NOT already directly curated for BCL7B itself -- a lead worth checking, not a confirmed association.
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