ASB8 (ankyrin repeat and SOCS box containing 8)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 140461
• Gene name: Ankyrin repeat and SOCS box containing 8
• Gene symbol: ASB8
• Synonyms (NCBI Gene): PP14212
• Chromosome: 12
• Chromosome location: 12q13.11

miRNA Show/Hide all (284)

miRTarBase ID	miRNA	Experiments	Reference
MIRT040179	hsa-miR-615-3p	CLASH	23622248
MIRT647794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT647793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT647792	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT647791	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT647790	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT647789	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT647788	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT647787	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT647786	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT647785	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT647784	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT647783	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT647782	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT647781	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT647780	hsa-miR-640	HITS-CLIP	23824327
MIRT647779	hsa-miR-5089-5p	HITS-CLIP	23824327
MIRT647794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT647793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT647792	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT647791	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT647790	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT647789	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT647788	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT647787	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT647786	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT647785	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT647784	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT647783	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT647782	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT647781	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT647780	hsa-miR-640	HITS-CLIP	23824327
MIRT647779	hsa-miR-5089-5p	HITS-CLIP	23824327
MIRT802548	hsa-miR-1279	CLIP-seq
MIRT802549	hsa-miR-154	CLIP-seq
MIRT802550	hsa-miR-24	CLIP-seq
MIRT802551	hsa-miR-27a	CLIP-seq
MIRT802552	hsa-miR-27b	CLIP-seq
MIRT802553	hsa-miR-3122	CLIP-seq
MIRT802554	hsa-miR-3155	CLIP-seq
MIRT802555	hsa-miR-3155b	CLIP-seq
MIRT802556	hsa-miR-3179	CLIP-seq
MIRT802557	hsa-miR-3202	CLIP-seq
MIRT802558	hsa-miR-3689d	CLIP-seq
MIRT802559	hsa-miR-378g	CLIP-seq
MIRT802560	hsa-miR-3913-5p	CLIP-seq
MIRT802561	hsa-miR-3977	CLIP-seq
MIRT802562	hsa-miR-4275	CLIP-seq
MIRT802563	hsa-miR-4284	CLIP-seq
MIRT802564	hsa-miR-4437	CLIP-seq
MIRT802565	hsa-miR-4438	CLIP-seq
MIRT802566	hsa-miR-4504	CLIP-seq
MIRT802567	hsa-miR-4505	CLIP-seq
MIRT802568	hsa-miR-4634	CLIP-seq
MIRT802569	hsa-miR-4674	CLIP-seq
MIRT802570	hsa-miR-4715-3p	CLIP-seq
MIRT802571	hsa-miR-4747-5p	CLIP-seq
MIRT802572	hsa-miR-4772-3p	CLIP-seq
MIRT802573	hsa-miR-4802-5p	CLIP-seq
MIRT802574	hsa-miR-484	CLIP-seq
MIRT802575	hsa-miR-5095	CLIP-seq
MIRT802576	hsa-miR-5096	CLIP-seq
MIRT802577	hsa-miR-513a-5p	CLIP-seq
MIRT802578	hsa-miR-542-3p	CLIP-seq
MIRT802579	hsa-miR-583	CLIP-seq
MIRT802580	hsa-miR-659	CLIP-seq
MIRT802581	hsa-miR-758	CLIP-seq
MIRT1936927	hsa-miR-1200	CLIP-seq
MIRT1936928	hsa-miR-122	CLIP-seq
MIRT1936929	hsa-miR-1278	CLIP-seq
MIRT1936930	hsa-miR-130a	CLIP-seq
MIRT1936931	hsa-miR-130b	CLIP-seq
MIRT1936932	hsa-miR-1343	CLIP-seq
MIRT1936933	hsa-miR-150	CLIP-seq
MIRT802549	hsa-miR-154	CLIP-seq
MIRT1936934	hsa-miR-198	CLIP-seq
MIRT1936935	hsa-miR-2114	CLIP-seq
MIRT1936936	hsa-miR-217	CLIP-seq
MIRT802550	hsa-miR-24	CLIP-seq
MIRT802551	hsa-miR-27a	CLIP-seq
MIRT802552	hsa-miR-27b	CLIP-seq
MIRT1936937	hsa-miR-301a	CLIP-seq
MIRT1936938	hsa-miR-301b	CLIP-seq
MIRT1936939	hsa-miR-3120-5p	CLIP-seq
MIRT1936940	hsa-miR-3135b	CLIP-seq
MIRT1936941	hsa-miR-3182	CLIP-seq
MIRT1936942	hsa-miR-3184	CLIP-seq
MIRT1936943	hsa-miR-3652	CLIP-seq
MIRT1936944	hsa-miR-3666	CLIP-seq
MIRT802558	hsa-miR-3689d	CLIP-seq
MIRT1936945	hsa-miR-3934	CLIP-seq
MIRT1936946	hsa-miR-423-5p	CLIP-seq
MIRT802562	hsa-miR-4275	CLIP-seq
MIRT802563	hsa-miR-4284	CLIP-seq
MIRT1936947	hsa-miR-4295	CLIP-seq
MIRT1936948	hsa-miR-4324	CLIP-seq
MIRT1936949	hsa-miR-4418	CLIP-seq
MIRT1936950	hsa-miR-4430	CLIP-seq
MIRT802566	hsa-miR-4504	CLIP-seq
MIRT1936951	hsa-miR-454	CLIP-seq
MIRT1936952	hsa-miR-4645-5p	CLIP-seq
MIRT1936953	hsa-miR-4659a-3p	CLIP-seq
MIRT1936954	hsa-miR-4659b-3p	CLIP-seq
MIRT1936955	hsa-miR-4673	CLIP-seq
MIRT802572	hsa-miR-4772-3p	CLIP-seq
MIRT1936956	hsa-miR-509-3-5p	CLIP-seq
MIRT1936957	hsa-miR-509-5p	CLIP-seq
MIRT802576	hsa-miR-5096	CLIP-seq
MIRT802577	hsa-miR-513a-5p	CLIP-seq
MIRT802578	hsa-miR-542-3p	CLIP-seq
MIRT1936958	hsa-miR-544b	CLIP-seq
MIRT1936959	hsa-miR-548aa	CLIP-seq
MIRT802579	hsa-miR-583	CLIP-seq
MIRT1936960	hsa-miR-652	CLIP-seq
MIRT1936961	hsa-miR-764	CLIP-seq
MIRT1936962	hsa-miR-9	CLIP-seq
MIRT802548	hsa-miR-1279	CLIP-seq
MIRT1936932	hsa-miR-1343	CLIP-seq
MIRT1936933	hsa-miR-150	CLIP-seq
MIRT2176747	hsa-miR-199a-3p	CLIP-seq
MIRT2176748	hsa-miR-199b-3p	CLIP-seq
MIRT2176749	hsa-miR-223	CLIP-seq
MIRT802550	hsa-miR-24	CLIP-seq
MIRT2176750	hsa-miR-3129-5p	CLIP-seq
MIRT802558	hsa-miR-3689d	CLIP-seq
MIRT1936945	hsa-miR-3934	CLIP-seq
MIRT2176751	hsa-miR-411	CLIP-seq
MIRT802563	hsa-miR-4284	CLIP-seq
MIRT802564	hsa-miR-4437	CLIP-seq
MIRT802565	hsa-miR-4438	CLIP-seq
MIRT802566	hsa-miR-4504	CLIP-seq
MIRT802569	hsa-miR-4674	CLIP-seq
MIRT2176752	hsa-miR-4697-3p	CLIP-seq
MIRT802570	hsa-miR-4715-3p	CLIP-seq
MIRT2176753	hsa-miR-4735-5p	CLIP-seq
MIRT802572	hsa-miR-4772-3p	CLIP-seq
MIRT2176754	hsa-miR-4775	CLIP-seq
MIRT2176755	hsa-miR-483-5p	CLIP-seq
MIRT802575	hsa-miR-5095	CLIP-seq
MIRT802577	hsa-miR-513a-5p	CLIP-seq
MIRT802578	hsa-miR-542-3p	CLIP-seq
MIRT2176756	hsa-miR-590-3p	CLIP-seq
MIRT2176757	hsa-miR-592	CLIP-seq
MIRT2176758	hsa-miR-597	CLIP-seq
MIRT802581	hsa-miR-758	CLIP-seq
MIRT1936961	hsa-miR-764	CLIP-seq
MIRT2176759	hsa-miR-936	CLIP-seq
MIRT2444085	hsa-miR-3149	CLIP-seq
MIRT2176751	hsa-miR-411	CLIP-seq
MIRT802565	hsa-miR-4438	CLIP-seq
MIRT802570	hsa-miR-4715-3p	CLIP-seq
MIRT2176753	hsa-miR-4735-5p	CLIP-seq
MIRT2176754	hsa-miR-4775	CLIP-seq
MIRT2176755	hsa-miR-483-5p	CLIP-seq
MIRT802575	hsa-miR-5095	CLIP-seq
MIRT2176756	hsa-miR-590-3p	CLIP-seq
MIRT2444085	hsa-miR-3149	CLIP-seq
MIRT2176751	hsa-miR-411	CLIP-seq
MIRT802570	hsa-miR-4715-3p	CLIP-seq
MIRT2176753	hsa-miR-4735-5p	CLIP-seq
MIRT2176754	hsa-miR-4775	CLIP-seq
MIRT2176755	hsa-miR-483-5p	CLIP-seq
MIRT2176756	hsa-miR-590-3p	CLIP-seq
MIRT1936927	hsa-miR-1200	CLIP-seq
MIRT2480125	hsa-miR-1205	CLIP-seq
MIRT1936928	hsa-miR-122	CLIP-seq
MIRT1936929	hsa-miR-1278	CLIP-seq
MIRT802548	hsa-miR-1279	CLIP-seq
MIRT1936930	hsa-miR-130a	CLIP-seq
MIRT1936931	hsa-miR-130b	CLIP-seq
MIRT1936932	hsa-miR-1343	CLIP-seq
MIRT1936933	hsa-miR-150	CLIP-seq
MIRT2480126	hsa-miR-1909	CLIP-seq
MIRT2480127	hsa-miR-1912	CLIP-seq
MIRT1936934	hsa-miR-198	CLIP-seq
MIRT2480128	hsa-miR-19a	CLIP-seq
MIRT2480129	hsa-miR-19b	CLIP-seq
MIRT1936936	hsa-miR-217	CLIP-seq
MIRT2480130	hsa-miR-22	CLIP-seq
MIRT802550	hsa-miR-24	CLIP-seq
MIRT1936937	hsa-miR-301a	CLIP-seq
MIRT1936938	hsa-miR-301b	CLIP-seq
MIRT1936940	hsa-miR-3135b	CLIP-seq
MIRT2444085	hsa-miR-3149	CLIP-seq
MIRT2480131	hsa-miR-3153	CLIP-seq
MIRT802554	hsa-miR-3155	CLIP-seq
MIRT802555	hsa-miR-3155b	CLIP-seq
MIRT1936943	hsa-miR-3652	CLIP-seq
MIRT1936944	hsa-miR-3666	CLIP-seq
MIRT2480132	hsa-miR-3667-5p	CLIP-seq
MIRT2480133	hsa-miR-3714	CLIP-seq
MIRT802559	hsa-miR-378g	CLIP-seq
MIRT1936945	hsa-miR-3934	CLIP-seq
MIRT2176751	hsa-miR-411	CLIP-seq
MIRT802563	hsa-miR-4284	CLIP-seq
MIRT1936947	hsa-miR-4295	CLIP-seq
MIRT1936948	hsa-miR-4324	CLIP-seq
MIRT1936949	hsa-miR-4418	CLIP-seq
MIRT1936950	hsa-miR-4430	CLIP-seq
MIRT802564	hsa-miR-4437	CLIP-seq
MIRT802565	hsa-miR-4438	CLIP-seq
MIRT802567	hsa-miR-4505	CLIP-seq
MIRT1936951	hsa-miR-454	CLIP-seq
MIRT802568	hsa-miR-4634	CLIP-seq
MIRT1936952	hsa-miR-4645-5p	CLIP-seq
MIRT2480134	hsa-miR-4668-5p	CLIP-seq
MIRT1936955	hsa-miR-4673	CLIP-seq
MIRT802569	hsa-miR-4674	CLIP-seq
MIRT2480135	hsa-miR-4690-3p	CLIP-seq
MIRT802570	hsa-miR-4715-3p	CLIP-seq
MIRT2176753	hsa-miR-4735-5p	CLIP-seq
MIRT2480136	hsa-miR-4763-5p	CLIP-seq
MIRT802572	hsa-miR-4772-3p	CLIP-seq
MIRT2176754	hsa-miR-4775	CLIP-seq
MIRT2176755	hsa-miR-483-5p	CLIP-seq
MIRT802574	hsa-miR-484	CLIP-seq
MIRT2480137	hsa-miR-498	CLIP-seq
MIRT1936956	hsa-miR-509-3-5p	CLIP-seq
MIRT802575	hsa-miR-5095	CLIP-seq
MIRT1936957	hsa-miR-509-5p	CLIP-seq
MIRT802577	hsa-miR-513a-5p	CLIP-seq
MIRT1936958	hsa-miR-544b	CLIP-seq
MIRT2480138	hsa-miR-548an	CLIP-seq
MIRT2480139	hsa-miR-558	CLIP-seq
MIRT2480140	hsa-miR-587	CLIP-seq
MIRT2176756	hsa-miR-590-3p	CLIP-seq
MIRT1936960	hsa-miR-652	CLIP-seq
MIRT2480141	hsa-miR-759	CLIP-seq
MIRT1936961	hsa-miR-764	CLIP-seq
MIRT2480125	hsa-miR-1205	CLIP-seq
MIRT1936928	hsa-miR-122	CLIP-seq
MIRT1936929	hsa-miR-1278	CLIP-seq
MIRT802548	hsa-miR-1279	CLIP-seq
MIRT1936930	hsa-miR-130a	CLIP-seq
MIRT1936931	hsa-miR-130b	CLIP-seq
MIRT1936932	hsa-miR-1343	CLIP-seq
MIRT1936933	hsa-miR-150	CLIP-seq
MIRT2480126	hsa-miR-1909	CLIP-seq
MIRT2480127	hsa-miR-1912	CLIP-seq
MIRT1936934	hsa-miR-198	CLIP-seq
MIRT1936936	hsa-miR-217	CLIP-seq
MIRT2480130	hsa-miR-22	CLIP-seq
MIRT802550	hsa-miR-24	CLIP-seq
MIRT1936937	hsa-miR-301a	CLIP-seq
MIRT1936938	hsa-miR-301b	CLIP-seq
MIRT1936940	hsa-miR-3135b	CLIP-seq
MIRT2444085	hsa-miR-3149	CLIP-seq
MIRT802554	hsa-miR-3155	CLIP-seq
MIRT802555	hsa-miR-3155b	CLIP-seq
MIRT1936943	hsa-miR-3652	CLIP-seq
MIRT1936944	hsa-miR-3666	CLIP-seq
MIRT2480132	hsa-miR-3667-5p	CLIP-seq
MIRT802559	hsa-miR-378g	CLIP-seq
MIRT1936945	hsa-miR-3934	CLIP-seq
MIRT2176751	hsa-miR-411	CLIP-seq
MIRT802563	hsa-miR-4284	CLIP-seq
MIRT1936947	hsa-miR-4295	CLIP-seq
MIRT1936949	hsa-miR-4418	CLIP-seq
MIRT1936950	hsa-miR-4430	CLIP-seq
MIRT802564	hsa-miR-4437	CLIP-seq
MIRT802565	hsa-miR-4438	CLIP-seq
MIRT802567	hsa-miR-4505	CLIP-seq
MIRT1936951	hsa-miR-454	CLIP-seq
MIRT802568	hsa-miR-4634	CLIP-seq
MIRT1936952	hsa-miR-4645-5p	CLIP-seq
MIRT1936955	hsa-miR-4673	CLIP-seq
MIRT802569	hsa-miR-4674	CLIP-seq
MIRT2480135	hsa-miR-4690-3p	CLIP-seq
MIRT802570	hsa-miR-4715-3p	CLIP-seq
MIRT2176753	hsa-miR-4735-5p	CLIP-seq
MIRT2480136	hsa-miR-4763-5p	CLIP-seq
MIRT802572	hsa-miR-4772-3p	CLIP-seq
MIRT2176754	hsa-miR-4775	CLIP-seq
MIRT2176755	hsa-miR-483-5p	CLIP-seq
MIRT802574	hsa-miR-484	CLIP-seq
MIRT1936956	hsa-miR-509-3-5p	CLIP-seq
MIRT802575	hsa-miR-5095	CLIP-seq
MIRT1936957	hsa-miR-509-5p	CLIP-seq
MIRT2480139	hsa-miR-558	CLIP-seq
MIRT2480140	hsa-miR-587	CLIP-seq
MIRT2176756	hsa-miR-590-3p	CLIP-seq
MIRT1936960	hsa-miR-652	CLIP-seq
MIRT2480141	hsa-miR-759	CLIP-seq
MIRT1936961	hsa-miR-764	CLIP-seq

Gene ontology (GO) Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0016567	Process	Protein ubiquitination	IEA
GO:0035556	Process	Intracellular signal transduction	IEA

Other IDs

• MIM: 615053
• HGNC: 17183
• e!Ensembl: ENSG00000177981

Protein

• UniProt ID: Q9H765
• Protein name: Ankyrin repeat and SOCS box protein 8 (ASB-8)
• Protein function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits IFN-beta produ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07525	SOCS_box	247 → 287	SOCS box	Domain
  PF12796	Ank_2	100 → 181	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	25 → 115	Ankyrin repeats (3 copies)	Repeat

• Tissue specificity: TISSUE SPECIFICITY: Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas. {ECO:0000269|PubMed:12559969}.
• Sequence:

  MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
  CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
  PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
  NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
  TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE

• Sequence length: 288

Pathways

Reactome Pathway

Neddylation

Antigen processing: Ubiquitination & Proteasome degradation

Related Genes

No strongly related genes found yet for ASB8.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ASB8.