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Gene Gene information from NCBI Gene database.
Entrez ID 92591
Gene name Ankyrin repeat and SOCS box containing 16
Gene symbol ASB16
Synonyms (NCBI Gene)
-
Chromosome 17
Chromosome location 17q21.31
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) protein
miRNA miRNA information provided by mirtarbase database.
518 Show/Hide all (518)
miRTarBase ID miRNA Experiments Reference
MIRT695580 hsa-miR-125a-5p HITS-CLIP 23313552
MIRT695579 hsa-miR-125b-5p HITS-CLIP 23313552
MIRT695577 hsa-miR-4319 HITS-CLIP 23313552
MIRT695578 hsa-miR-4481 HITS-CLIP 23313552
MIRT695576 hsa-miR-4745-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 17474147
GO:0005829 Component Cytosol IEA
GO:0005829 Component Cytosol TAS
GO:0016567 Process Protein ubiquitination IEA
GO:0035556 Process Intracellular signal transduction IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615056 19768 ENSG00000161664
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96NS5
Protein name Ankyrin repeat and SOCS box protein 16 (ASB-16)
Protein function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07525 SOCS_box 408 → 446 SOCS box Domain
PF12796 Ank_2 147 → 240 Ankyrin repeats (3 copies) Repeat
PF12796 Ank_2 56 → 172 Ankyrin repeats (3 copies) Repeat
PF12796 Ank_2 183 → 279 Ankyrin repeats (3 copies) Repeat
Sequence
MARETFPFTSSMLRSLRLQQEWLEWEDRRRAAAQQCRSRRCPSSPRARLTRPHRSCRDPA
VHQALFSGNLQQVQALFQDEEAANMIVETVSNQLAWSAEQGFWVLTPKTKQTAPLAIATA
RGYTDCARHLIRQGAELDARVGGRAA
LHEACARAQFDCVRLLLTFGAKANVLTEEGTTPL
HLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRT
SQGETALNTACAGAEGPGSCRRHQAAARRLLEAGADARA
AGRKRHTPLHNACANGCGGLA
ELLLRYGARAEVPNGAGHTPMDCALQAVQDSPNWEPEVLFAALLDYGAQPVRPEMLKHCA
NFPRALEVLLNAYPCVPSCETWVEAVLPELWKEHEAFYSSALCMVNQPRQLQHLARLAVR
ARLGSRCRQGATRLPLPPLLRDYLLL
RVEGCIQ
Sequence length 453
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation