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Gene Gene information from NCBI Gene database.
Entrez ID 79754
Gene name Ankyrin repeat and SOCS box containing 13
Gene symbol ASB13
Synonyms (NCBI Gene)
-
Chromosome 10
Chromosome location 10p15.1
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) protein
miRNA miRNA information provided by mirtarbase database.
293 Show/Hide all (293)
miRTarBase ID miRNA Experiments Reference
MIRT019461 hsa-miR-148b-3p Microarray 17612493
MIRT047299 hsa-miR-181b-5p CLASH 23622248
MIRT802050 hsa-miR-1228 CLIP-seq
MIRT802051 hsa-miR-125a-5p CLIP-seq
MIRT802052 hsa-miR-125b CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16169070, 16189514, 25416956, 26972000, 29892012, 32296183, 32814053, 33961781
GO:0005829 Component Cytosol IEA
GO:0005829 Component Cytosol TAS
GO:0016567 Process Protein ubiquitination IEA
GO:0035556 Process Intracellular signal transduction IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615055 19765 ENSG00000196372
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WXK3
Protein name Ankyrin repeat and SOCS box protein 13 (ASB-13)
Protein function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07525 SOCS_box 239 → 277 SOCS box Domain
PF12796 Ank_2 121 → 212 Ankyrin repeats (3 copies) Repeat
PF12796 Ank_2 23 → 115 Ankyrin repeats (3 copies) Repeat
PF12796 Ank_2 79 → 147 Ankyrin repeats (3 copies) Repeat
Sequence
MEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAAS
LQGQARCVQLLLAAGAQV
DARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASP
LHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAK
LHETALHHAAKVKNVDLIEMLIEFGGNIYARD
NRGKKPSDYTWSSSAPAKCFEYYEKTPL
TLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSY
N
Sequence length 278
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation