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Gene Gene information from NCBI Gene database.
Entrez ID 10776
Gene name CAMP regulated phosphoprotein 19
Gene symbol ARPP19
Synonyms (NCBI Gene)
ARPP-16ARPP-19ARPP16ENSAL
Chromosome 15
Chromosome location 15q21.2
Summary The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A (PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 [PubMed 21164014]).[supplied by OMIM, Feb 2011]
miRNA miRNA information provided by mirtarbase database.
2207 Show/Hide all (2207)
miRTarBase ID miRNA Experiments Reference
MIRT016628 hsa-miR-451a Microarray 20218812
MIRT051971 hsa-let-7b-5p CLASH 23622248
MIRT049208 hsa-miR-92a-3p CLASH 23622248
MIRT048510 hsa-miR-100-5p CLASH 23622248
MIRT044725 hsa-miR-320a CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21 Show/Hide all (21)
GO ID Ontology Definition Evidence Reference
GO:0000086 Process G2/M transition of mitotic cell cycle IMP 21164014
GO:0000278 Process Mitotic cell cycle IMP 21164014
GO:0004864 Function Protein phosphatase inhibitor activity IBA
GO:0004864 Function Protein phosphatase inhibitor activity IDA 38123684
GO:0004864 Function Protein phosphatase inhibitor activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605487 16967 ENSG00000128989
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P56211
Protein name cAMP-regulated phosphoprotein 19 (ARPP-19)
Protein function Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis (PubMed:38123684). Inhibition of PP2A is enhanced when ARPP19 is phosphorylated (PubMed:38123684). When phosphorylated at Ser-62 during mitosis
PDB 8TTB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04667 Endosulfine 20 → 109 cAMP-regulated phosphoprotein/endosulfine conserved region Family
Sequence
Sequence length 112
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
MASTL Facilitates Mitotic Progression