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Gene Gene information from NCBI Gene database.
Entrez ID 400
Gene name ARF like GTPase 1
Gene symbol ARL1
Synonyms (NCBI Gene)
ARFL1
Chromosome 12
Chromosome location 12q23.2
Summary The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity,
miRNA miRNA information provided by mirtarbase database.
611 Show/Hide all (611)
miRTarBase ID miRNA Experiments Reference
MIRT020262 hsa-miR-130b-3p Sequencing 20371350
MIRT028155 hsa-miR-93-5p Sequencing 20371350
MIRT030486 hsa-miR-24-3p Microarray 19748357
MIRT039171 hsa-miR-769-5p CLASH 23622248
MIRT441188 hsa-miR-106b-5p HITS-CLIP 22473208
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
29 Show/Hide all (29)
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000166 Function Nucleotide binding IEA
GO:0003924 Function GTPase activity IDA 8798635, 9624189
GO:0003924 Function GTPase activity IEA
GO:0005515 Function Protein binding IPI 22981988, 35271311
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603425 692 ENSG00000120805
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P40616
Protein name ADP-ribosylation factor-like protein 1
Protein function GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex (PubMed:21239483, PubMed:22679020, PubMed:27373159, PubMed:27436755, PubM
PDB 1UPT , 4DCN , 5EE5 , 5J5C
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00025 Arf 5 → 177 ADP-ribosylation factor family Domain
Tissue specificity TISSUE SPECIFICITY: Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9624189}.
Sequence
Sequence length 181
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Retrograde transport at the Trans-Golgi-Network