Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	23647
Gene name	ARF interacting protein 2
Gene symbol	ARFIP2
Synonyms (NCBI Gene)	POR1
Chromosome	11
Chromosome location	11p15.4

189 Show/Hide all (189)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001570	hsa-miR-155-5p	pSILAC	18668040
MIRT001570	hsa-miR-155-5p	Proteomics;Other	18668040
MIRT029664	hsa-miR-26b-5p	Microarray	19088304
MIRT032409	hsa-let-7b-5p	Proteomics	18668040
MIRT638984	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT638983	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT638982	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT638981	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT638980	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT638979	hsa-miR-8057	HITS-CLIP	23824327
MIRT734455	hsa-miR-338-3p	Luciferase reporter assayWestern blottingImmunoprecipitaion (IP)qRT-PCR	33837886
MIRT638984	hsa-miR-181a-2-3p	HITS-CLIP	23824327
MIRT638983	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT638982	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT638981	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT638980	hsa-miR-6509-3p	HITS-CLIP	23824327
MIRT638979	hsa-miR-8057	HITS-CLIP	23824327
MIRT793232	hsa-miR-122	CLIP-seq
MIRT793233	hsa-miR-3135b	CLIP-seq
MIRT793234	hsa-miR-3652	CLIP-seq
MIRT793235	hsa-miR-4423-5p	CLIP-seq
MIRT793236	hsa-miR-4430	CLIP-seq
MIRT793237	hsa-miR-1193	CLIP-seq
MIRT793238	hsa-miR-1228	CLIP-seq
MIRT793239	hsa-miR-1245b-3p	CLIP-seq
MIRT793240	hsa-miR-1245b-5p	CLIP-seq
MIRT793241	hsa-miR-1262	CLIP-seq
MIRT793242	hsa-miR-1281	CLIP-seq
MIRT793243	hsa-miR-1293	CLIP-seq
MIRT793244	hsa-miR-1976	CLIP-seq
MIRT793245	hsa-miR-2276	CLIP-seq
MIRT793246	hsa-miR-2392	CLIP-seq
MIRT793247	hsa-miR-3142	CLIP-seq
MIRT793248	hsa-miR-3152-3p	CLIP-seq
MIRT793249	hsa-miR-3661	CLIP-seq
MIRT793250	hsa-miR-377	CLIP-seq
MIRT793251	hsa-miR-3922-5p	CLIP-seq
MIRT793252	hsa-miR-3942-3p	CLIP-seq
MIRT793253	hsa-miR-4299	CLIP-seq
MIRT793254	hsa-miR-4454	CLIP-seq
MIRT793255	hsa-miR-4483	CLIP-seq
MIRT793256	hsa-miR-4532	CLIP-seq
MIRT793257	hsa-miR-4662a-5p	CLIP-seq
MIRT793258	hsa-miR-4676-5p	CLIP-seq
MIRT793259	hsa-miR-4695-3p	CLIP-seq
MIRT793260	hsa-miR-4701-3p	CLIP-seq
MIRT793261	hsa-miR-4707-3p	CLIP-seq
MIRT793262	hsa-miR-4708-3p	CLIP-seq
MIRT793263	hsa-miR-4710	CLIP-seq
MIRT793264	hsa-miR-4753-5p	CLIP-seq
MIRT793265	hsa-miR-5096	CLIP-seq
MIRT793266	hsa-miR-548g	CLIP-seq
MIRT793267	hsa-miR-575	CLIP-seq
MIRT793268	hsa-miR-629	CLIP-seq
MIRT793269	hsa-miR-631	CLIP-seq
MIRT793270	hsa-miR-103b	CLIP-seq
MIRT793238	hsa-miR-1228	CLIP-seq
MIRT793271	hsa-miR-1252	CLIP-seq
MIRT793241	hsa-miR-1262	CLIP-seq
MIRT793242	hsa-miR-1281	CLIP-seq
MIRT793243	hsa-miR-1293	CLIP-seq
MIRT793272	hsa-miR-1306	CLIP-seq
MIRT793273	hsa-miR-146b-3p	CLIP-seq
MIRT793244	hsa-miR-1976	CLIP-seq
MIRT793245	hsa-miR-2276	CLIP-seq
MIRT793274	hsa-miR-3156-5p	CLIP-seq
MIRT793275	hsa-miR-3190	CLIP-seq
MIRT793276	hsa-miR-3192	CLIP-seq
MIRT793277	hsa-miR-3199	CLIP-seq
MIRT793278	hsa-miR-3202	CLIP-seq
MIRT793279	hsa-miR-3611	CLIP-seq
MIRT793280	hsa-miR-3616-5p	CLIP-seq
MIRT793281	hsa-miR-3647-5p	CLIP-seq
MIRT793250	hsa-miR-377	CLIP-seq
MIRT793282	hsa-miR-4279	CLIP-seq
MIRT793283	hsa-miR-4314	CLIP-seq
MIRT793284	hsa-miR-4435	CLIP-seq
MIRT793255	hsa-miR-4483	CLIP-seq
MIRT793256	hsa-miR-4532	CLIP-seq
MIRT793285	hsa-miR-4533	CLIP-seq
MIRT793286	hsa-miR-4646-5p	CLIP-seq
MIRT793287	hsa-miR-4687-3p	CLIP-seq
MIRT793288	hsa-miR-4700-3p	CLIP-seq
MIRT793260	hsa-miR-4701-3p	CLIP-seq
MIRT793263	hsa-miR-4710	CLIP-seq
MIRT793289	hsa-miR-4722-3p	CLIP-seq
MIRT793290	hsa-miR-4740-3p	CLIP-seq
MIRT793291	hsa-miR-4759	CLIP-seq
MIRT793292	hsa-miR-4786-3p	CLIP-seq
MIRT793293	hsa-miR-4795-5p	CLIP-seq
MIRT793266	hsa-miR-548g	CLIP-seq
MIRT793294	hsa-miR-573	CLIP-seq
MIRT793295	hsa-miR-647	CLIP-seq
MIRT793296	hsa-miR-663b	CLIP-seq
MIRT1934084	hsa-miR-106a	CLIP-seq
MIRT1934085	hsa-miR-106b	CLIP-seq
MIRT1934086	hsa-miR-17	CLIP-seq
MIRT1934087	hsa-miR-20a	CLIP-seq
MIRT1934088	hsa-miR-20b	CLIP-seq
MIRT793245	hsa-miR-2276	CLIP-seq
MIRT1934089	hsa-miR-302a	CLIP-seq
MIRT1934090	hsa-miR-302b	CLIP-seq
MIRT1934091	hsa-miR-302c	CLIP-seq
MIRT1934092	hsa-miR-302d	CLIP-seq
MIRT1934093	hsa-miR-302e	CLIP-seq
MIRT1934094	hsa-miR-3616-3p	CLIP-seq
MIRT1934095	hsa-miR-3620	CLIP-seq
MIRT1934096	hsa-miR-372	CLIP-seq
MIRT1934097	hsa-miR-373	CLIP-seq
MIRT1934098	hsa-miR-4731-5p	CLIP-seq
MIRT1934099	hsa-miR-512-3p	CLIP-seq
MIRT1934100	hsa-miR-519d	CLIP-seq
MIRT1934101	hsa-miR-520a-3p	CLIP-seq
MIRT1934102	hsa-miR-520b	CLIP-seq
MIRT1934103	hsa-miR-520c-3p	CLIP-seq
MIRT1934104	hsa-miR-520d-3p	CLIP-seq
MIRT1934105	hsa-miR-520e	CLIP-seq
MIRT1934106	hsa-miR-520g	CLIP-seq
MIRT1934107	hsa-miR-520h	CLIP-seq
MIRT1934108	hsa-miR-93	CLIP-seq
MIRT793232	hsa-miR-122	CLIP-seq
MIRT793238	hsa-miR-1228	CLIP-seq
MIRT1934109	hsa-miR-1267	CLIP-seq
MIRT793242	hsa-miR-1281	CLIP-seq
MIRT793244	hsa-miR-1976	CLIP-seq
MIRT793245	hsa-miR-2276	CLIP-seq
MIRT793233	hsa-miR-3135b	CLIP-seq
MIRT1934095	hsa-miR-3620	CLIP-seq
MIRT793234	hsa-miR-3652	CLIP-seq
MIRT793250	hsa-miR-377	CLIP-seq
MIRT793282	hsa-miR-4279	CLIP-seq
MIRT793235	hsa-miR-4423-5p	CLIP-seq
MIRT793236	hsa-miR-4430	CLIP-seq
MIRT793256	hsa-miR-4532	CLIP-seq
MIRT793289	hsa-miR-4722-3p	CLIP-seq
MIRT793290	hsa-miR-4740-3p	CLIP-seq
MIRT793245	hsa-miR-2276	CLIP-seq
MIRT2173962	hsa-miR-4270	CLIP-seq
MIRT2173963	hsa-miR-4283	CLIP-seq
MIRT793284	hsa-miR-4435	CLIP-seq
MIRT2173964	hsa-miR-4441	CLIP-seq
MIRT2173965	hsa-miR-22	CLIP-seq
MIRT793249	hsa-miR-3661	CLIP-seq
MIRT793269	hsa-miR-631	CLIP-seq
MIRT793244	hsa-miR-1976	CLIP-seq
MIRT2384364	hsa-miR-4293	CLIP-seq
MIRT2384365	hsa-miR-4709-3p	CLIP-seq
MIRT2384366	hsa-miR-4797-3p	CLIP-seq
MIRT2435445	hsa-miR-1253	CLIP-seq
MIRT2435446	hsa-miR-1289	CLIP-seq
MIRT2435447	hsa-miR-1915	CLIP-seq
MIRT2173965	hsa-miR-22	CLIP-seq
MIRT2435448	hsa-miR-3136-3p	CLIP-seq
MIRT2435449	hsa-miR-328	CLIP-seq
MIRT2173962	hsa-miR-4270	CLIP-seq
MIRT2173964	hsa-miR-4441	CLIP-seq
MIRT2435450	hsa-miR-4769-3p	CLIP-seq
MIRT2435451	hsa-miR-558	CLIP-seq
MIRT793295	hsa-miR-647	CLIP-seq
MIRT2435446	hsa-miR-1289	CLIP-seq
MIRT2443860	hsa-miR-3126-5p	CLIP-seq
MIRT2443861	hsa-miR-3198	CLIP-seq
MIRT2443862	hsa-miR-4294	CLIP-seq
MIRT2443863	hsa-miR-4309	CLIP-seq
MIRT2443864	hsa-miR-4419a	CLIP-seq
MIRT2443865	hsa-miR-4471	CLIP-seq
MIRT2443866	hsa-miR-4510	CLIP-seq
MIRT2435446	hsa-miR-1289	CLIP-seq
MIRT2443860	hsa-miR-3126-5p	CLIP-seq
MIRT2443861	hsa-miR-3198	CLIP-seq
MIRT2443862	hsa-miR-4294	CLIP-seq
MIRT2443863	hsa-miR-4309	CLIP-seq
MIRT2443864	hsa-miR-4419a	CLIP-seq
MIRT2443865	hsa-miR-4471	CLIP-seq
MIRT2443866	hsa-miR-4510	CLIP-seq
MIRT793232	hsa-miR-122	CLIP-seq
MIRT793233	hsa-miR-3135b	CLIP-seq
MIRT793234	hsa-miR-3652	CLIP-seq
MIRT2173962	hsa-miR-4270	CLIP-seq
MIRT793235	hsa-miR-4423-5p	CLIP-seq
MIRT793236	hsa-miR-4430	CLIP-seq
MIRT2173964	hsa-miR-4441	CLIP-seq
MIRT2173962	hsa-miR-4270	CLIP-seq
MIRT2173964	hsa-miR-4441	CLIP-seq
MIRT793232	hsa-miR-122	CLIP-seq
MIRT793233	hsa-miR-3135b	CLIP-seq
MIRT793234	hsa-miR-3652	CLIP-seq
MIRT793235	hsa-miR-4423-5p	CLIP-seq
MIRT793236	hsa-miR-4430	CLIP-seq

35 Show/Hide all (35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000423	Process	Mitophagy	IMP	33773106
GO:0001726	Component	Ruffle	IMP	8670882
GO:0005515	Function	Protein binding	IPI	8670882, 9312003, 11346801, 16189514, 21516116, 21988832, 25416956, 29997244, 31467278, 32296183, 32814053, 32911434, 33961781, 35271311
GO:0005525	Function	GTP binding	TAS	8670882
GO:0005543	Function	Phospholipid binding	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IDA	25468996
GO:0005737	Component	Cytoplasm	TAS	9312003
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS	9312003
GO:0005938	Component	Cell cortex	IDA	9312003
GO:0006886	Process	Intracellular protein transport	IBA
GO:0006914	Process	Autophagy	IEA
GO:0007264	Process	Small GTPase-mediated signal transduction	TAS	8670882
GO:0008104	Process	Intracellular protein localization	IEA
GO:0016020	Component	Membrane	IEA
GO:0019904	Function	Protein domain specific binding	IEA
GO:0030032	Process	Lamellipodium assembly	TAS	9312003
GO:0030036	Process	Actin cytoskeleton organization	IMP	9312003
GO:0030742	Function	GTP-dependent protein binding	IPI	9312003
GO:0031267	Function	Small GTPase binding	TAS	9312003
GO:0031529	Process	Ruffle organization	TAS	9312003
GO:0032588	Component	Trans-Golgi network membrane	IBA
GO:0032588	Component	Trans-Golgi network membrane	IDA	23695357
GO:0032588	Component	Trans-Golgi network membrane	IEA
GO:0034315	Process	Regulation of Arp2/3 complex-mediated actin nucleation	IBA
GO:0034497	Process	Protein localization to phagophore assembly site	IMP	33773106
GO:0042802	Function	Identical protein binding	IPI	8670882, 25416956, 31515488, 32296183
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0070273	Function	Phosphatidylinositol-4-phosphate binding	IDA	23695357
GO:0070273	Function	Phosphatidylinositol-4-phosphate binding	IEA
GO:0140090	Function	Membrane curvature sensor activity	IDA	29768204

MIM	HGNC	e!Ensembl
601638	17160	ENSG00000132254

P53365

Protein name

Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (POR1)

Protein function

Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network (PubMed:26507660). May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted

PDB

1I49 , 1I4D , 1I4L , 1I4T , 4DCN

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06456	Arfaptin	89 → 316	Arfaptin-like domain	Domain

Sequence

MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGD
GLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSR
TVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQE
EFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRT
DLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLL
FHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ

Sequence length

341

Interactions

View interactions

Reactome Pathway
Retrograde transport at the Trans-Golgi-Network

Related Genes Genes most often co-reported with ARFIP2 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for ARFIP2.

Diseases Linked via Similar Genes Diseases curated for genes most similar to ARFIP2 (see Related Genes above), that are NOT already directly curated for ARFIP2 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to ARFIP2.

ARFIP2 (ARF interacting protein 2)

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