ARFIP1 (ARF interacting protein 1)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 27236
• Gene name: ARF interacting protein 1
• Gene symbol: ARFIP1
• Synonyms (NCBI Gene): HSU52521
• Chromosome: 4
• Chromosome location: 4q31.3

miRNA Show/Hide all (204)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001571	hsa-miR-155-5p	pSILAC	18668040
MIRT001571	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT001571	hsa-miR-155-5p	Proteomics	18668040
MIRT002668	hsa-miR-124-3p	Microarray	18668037
MIRT002668	hsa-miR-124-3p	Microarray	15685193
MIRT023478	hsa-miR-23b-3p	Sequencing	20371350
MIRT037039	hsa-miR-877-3p	CLASH	23622248
MIRT793167	hsa-miR-1206	CLIP-seq
MIRT793168	hsa-miR-125a-3p	CLIP-seq
MIRT793169	hsa-miR-1305	CLIP-seq
MIRT793170	hsa-miR-181a	CLIP-seq
MIRT793171	hsa-miR-181b	CLIP-seq
MIRT793172	hsa-miR-181c	CLIP-seq
MIRT793173	hsa-miR-181d	CLIP-seq
MIRT793174	hsa-miR-2053	CLIP-seq
MIRT793175	hsa-miR-3126-5p	CLIP-seq
MIRT793176	hsa-miR-3646	CLIP-seq
MIRT793177	hsa-miR-410	CLIP-seq
MIRT793178	hsa-miR-421	CLIP-seq
MIRT793179	hsa-miR-4262	CLIP-seq
MIRT793180	hsa-miR-4419a	CLIP-seq
MIRT793181	hsa-miR-4510	CLIP-seq
MIRT793182	hsa-miR-455-3p	CLIP-seq
MIRT793183	hsa-miR-4710	CLIP-seq
MIRT793184	hsa-miR-4762-5p	CLIP-seq
MIRT793185	hsa-miR-4775	CLIP-seq
MIRT793186	hsa-miR-485-3p	CLIP-seq
MIRT793187	hsa-miR-495	CLIP-seq
MIRT793188	hsa-miR-520d-5p	CLIP-seq
MIRT793189	hsa-miR-524-5p	CLIP-seq
MIRT793190	hsa-miR-543	CLIP-seq
MIRT793191	hsa-miR-548a-5p	CLIP-seq
MIRT793192	hsa-miR-548ab	CLIP-seq
MIRT793193	hsa-miR-548ak	CLIP-seq
MIRT793194	hsa-miR-548b-5p	CLIP-seq
MIRT793195	hsa-miR-548c-5p	CLIP-seq
MIRT793196	hsa-miR-548d-5p	CLIP-seq
MIRT793197	hsa-miR-548h	CLIP-seq
MIRT793198	hsa-miR-548i	CLIP-seq
MIRT793199	hsa-miR-548j	CLIP-seq
MIRT793200	hsa-miR-548k	CLIP-seq
MIRT793201	hsa-miR-548l	CLIP-seq
MIRT793202	hsa-miR-548w	CLIP-seq
MIRT793203	hsa-miR-548y	CLIP-seq
MIRT793204	hsa-miR-552	CLIP-seq
MIRT793205	hsa-miR-559	CLIP-seq
MIRT793206	hsa-miR-568	CLIP-seq
MIRT793207	hsa-miR-579	CLIP-seq
MIRT793208	hsa-miR-582-5p	CLIP-seq
MIRT793209	hsa-miR-590-3p	CLIP-seq
MIRT793210	hsa-miR-600	CLIP-seq
MIRT793167	hsa-miR-1206	CLIP-seq
MIRT793211	hsa-miR-1252	CLIP-seq
MIRT793212	hsa-miR-1911	CLIP-seq
MIRT793213	hsa-miR-3156-3p	CLIP-seq
MIRT793214	hsa-miR-3679-3p	CLIP-seq
MIRT793215	hsa-miR-4301	CLIP-seq
MIRT793216	hsa-miR-4476	CLIP-seq
MIRT793217	hsa-miR-4533	CLIP-seq
MIRT793218	hsa-miR-4700-3p	CLIP-seq
MIRT793185	hsa-miR-4775	CLIP-seq
MIRT793219	hsa-miR-532-3p	CLIP-seq
MIRT793206	hsa-miR-568	CLIP-seq
MIRT793207	hsa-miR-579	CLIP-seq
MIRT793209	hsa-miR-590-3p	CLIP-seq
MIRT793220	hsa-miR-155	CLIP-seq
MIRT793221	hsa-miR-19a	CLIP-seq
MIRT793222	hsa-miR-19b	CLIP-seq
MIRT793223	hsa-miR-2113	CLIP-seq
MIRT793224	hsa-miR-320a	CLIP-seq
MIRT793225	hsa-miR-320b	CLIP-seq
MIRT793226	hsa-miR-320c	CLIP-seq
MIRT793227	hsa-miR-320d	CLIP-seq
MIRT793228	hsa-miR-34b	CLIP-seq
MIRT793229	hsa-miR-34c-3p	CLIP-seq
MIRT793230	hsa-miR-4429	CLIP-seq
MIRT793231	hsa-miR-4696	CLIP-seq
MIRT793211	hsa-miR-1252	CLIP-seq
MIRT1934082	hsa-miR-642b	CLIP-seq
MIRT1934083	hsa-miR-3163	CLIP-seq
MIRT793224	hsa-miR-320a	CLIP-seq
MIRT793225	hsa-miR-320b	CLIP-seq
MIRT793226	hsa-miR-320c	CLIP-seq
MIRT793227	hsa-miR-320d	CLIP-seq
MIRT793230	hsa-miR-4429	CLIP-seq
MIRT793184	hsa-miR-4762-5p	CLIP-seq
MIRT793167	hsa-miR-1206	CLIP-seq
MIRT2173945	hsa-miR-147	CLIP-seq
MIRT793221	hsa-miR-19a	CLIP-seq
MIRT793222	hsa-miR-19b	CLIP-seq
MIRT2173946	hsa-miR-2110	CLIP-seq
MIRT2173947	hsa-miR-3138	CLIP-seq
MIRT793224	hsa-miR-320a	CLIP-seq
MIRT793225	hsa-miR-320b	CLIP-seq
MIRT793226	hsa-miR-320c	CLIP-seq
MIRT793227	hsa-miR-320d	CLIP-seq
MIRT2173948	hsa-miR-371b-5p	CLIP-seq
MIRT2173949	hsa-miR-377	CLIP-seq
MIRT2173950	hsa-miR-3911	CLIP-seq
MIRT2173951	hsa-miR-4271	CLIP-seq
MIRT2173952	hsa-miR-4314	CLIP-seq
MIRT793230	hsa-miR-4429	CLIP-seq
MIRT2173953	hsa-miR-4503	CLIP-seq
MIRT793182	hsa-miR-455-3p	CLIP-seq
MIRT2173954	hsa-miR-4667-5p	CLIP-seq
MIRT2173955	hsa-miR-4700-5p	CLIP-seq
MIRT2173956	hsa-miR-4725-3p	CLIP-seq
MIRT793184	hsa-miR-4762-5p	CLIP-seq
MIRT793185	hsa-miR-4775	CLIP-seq
MIRT2173957	hsa-miR-4800-5p	CLIP-seq
MIRT2173958	hsa-miR-558	CLIP-seq
MIRT793206	hsa-miR-568	CLIP-seq
MIRT793208	hsa-miR-582-5p	CLIP-seq
MIRT793209	hsa-miR-590-3p	CLIP-seq
MIRT793210	hsa-miR-600	CLIP-seq
MIRT2173959	hsa-miR-637	CLIP-seq
MIRT2173960	hsa-miR-644	CLIP-seq
MIRT2173961	hsa-miR-664	CLIP-seq
MIRT2477552	hsa-miR-1246	CLIP-seq
MIRT2477553	hsa-miR-1276	CLIP-seq
MIRT2477554	hsa-miR-1290	CLIP-seq
MIRT2477555	hsa-miR-186	CLIP-seq
MIRT2477556	hsa-miR-3167	CLIP-seq
MIRT2477557	hsa-miR-3185	CLIP-seq
MIRT2173948	hsa-miR-371b-5p	CLIP-seq
MIRT2477558	hsa-miR-4263	CLIP-seq
MIRT2477559	hsa-miR-4446-5p	CLIP-seq
MIRT2477560	hsa-miR-4652-3p	CLIP-seq
MIRT2477561	hsa-miR-4693-5p	CLIP-seq
MIRT2477562	hsa-miR-4777-3p	CLIP-seq
MIRT2477563	hsa-miR-548aa	CLIP-seq
MIRT2477564	hsa-miR-548ac	CLIP-seq
MIRT2477565	hsa-miR-548ae	CLIP-seq
MIRT2477566	hsa-miR-548aj	CLIP-seq
MIRT2477567	hsa-miR-548am	CLIP-seq
MIRT2477568	hsa-miR-548d-3p	CLIP-seq
MIRT2477569	hsa-miR-548x	CLIP-seq
MIRT2477570	hsa-miR-548z	CLIP-seq
MIRT2477571	hsa-miR-563	CLIP-seq
MIRT2477572	hsa-miR-576-5p	CLIP-seq
MIRT1934082	hsa-miR-642b	CLIP-seq
MIRT2477573	hsa-miR-876-5p	CLIP-seq
MIRT2675221	hsa-miR-1183	CLIP-seq
MIRT2675222	hsa-miR-124	CLIP-seq
MIRT2477552	hsa-miR-1246	CLIP-seq
MIRT2675223	hsa-miR-1253	CLIP-seq
MIRT2675224	hsa-miR-1258	CLIP-seq
MIRT2675225	hsa-miR-1260	CLIP-seq
MIRT2675226	hsa-miR-1260b	CLIP-seq
MIRT2477553	hsa-miR-1276	CLIP-seq
MIRT2675227	hsa-miR-1287	CLIP-seq
MIRT2477554	hsa-miR-1290	CLIP-seq
MIRT2477555	hsa-miR-186	CLIP-seq
MIRT2675228	hsa-miR-188-3p	CLIP-seq
MIRT2675229	hsa-miR-299-5p	CLIP-seq
MIRT2675230	hsa-miR-3135b	CLIP-seq
MIRT2675231	hsa-miR-3145-5p	CLIP-seq
MIRT793213	hsa-miR-3156-3p	CLIP-seq
MIRT2477556	hsa-miR-3167	CLIP-seq
MIRT2477557	hsa-miR-3185	CLIP-seq
MIRT2675232	hsa-miR-3200-5p	CLIP-seq
MIRT2675233	hsa-miR-3613-3p	CLIP-seq
MIRT2675234	hsa-miR-361-3p	CLIP-seq
MIRT2675235	hsa-miR-3653	CLIP-seq
MIRT2675236	hsa-miR-3658	CLIP-seq
MIRT793214	hsa-miR-3679-3p	CLIP-seq
MIRT2173948	hsa-miR-371b-5p	CLIP-seq
MIRT793177	hsa-miR-410	CLIP-seq
MIRT2675237	hsa-miR-4251	CLIP-seq
MIRT2477558	hsa-miR-4263	CLIP-seq
MIRT793215	hsa-miR-4301	CLIP-seq
MIRT2675238	hsa-miR-4329	CLIP-seq
MIRT2477559	hsa-miR-4446-5p	CLIP-seq
MIRT2675239	hsa-miR-4457	CLIP-seq
MIRT2675240	hsa-miR-4477b	CLIP-seq
MIRT2477560	hsa-miR-4652-3p	CLIP-seq
MIRT2675241	hsa-miR-4677-3p	CLIP-seq
MIRT2675242	hsa-miR-4679	CLIP-seq
MIRT2477561	hsa-miR-4693-5p	CLIP-seq
MIRT2675243	hsa-miR-4720-3p	CLIP-seq
MIRT2477562	hsa-miR-4777-3p	CLIP-seq
MIRT2675244	hsa-miR-4804-3p	CLIP-seq
MIRT2675245	hsa-miR-506	CLIP-seq
MIRT2675246	hsa-miR-508-5p	CLIP-seq
MIRT2675247	hsa-miR-513b	CLIP-seq
MIRT793219	hsa-miR-532-3p	CLIP-seq
MIRT2477563	hsa-miR-548aa	CLIP-seq
MIRT2477564	hsa-miR-548ac	CLIP-seq
MIRT2477565	hsa-miR-548ae	CLIP-seq
MIRT2477566	hsa-miR-548aj	CLIP-seq
MIRT2477567	hsa-miR-548am	CLIP-seq
MIRT2477568	hsa-miR-548d-3p	CLIP-seq
MIRT2477569	hsa-miR-548x	CLIP-seq
MIRT2477570	hsa-miR-548z	CLIP-seq
MIRT2675248	hsa-miR-553	CLIP-seq
MIRT2477571	hsa-miR-563	CLIP-seq
MIRT2477572	hsa-miR-576-5p	CLIP-seq
MIRT2675249	hsa-miR-578	CLIP-seq
MIRT2675250	hsa-miR-587	CLIP-seq
MIRT1934082	hsa-miR-642b	CLIP-seq
MIRT2675251	hsa-miR-662	CLIP-seq
MIRT2675252	hsa-miR-7	CLIP-seq
MIRT2477573	hsa-miR-876-5p	CLIP-seq
MIRT2675253	hsa-miR-888	CLIP-seq

Gene ontology (GO) Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	9038142
GO:0005515	Function	Protein binding	IPI	22981988, 32296183, 33961781, 35271311
GO:0005543	Function	Phospholipid binding	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	IDA	9038142
GO:0005829	Component	Cytosol	IEA
GO:0006886	Process	Intracellular protein transport	IBA
GO:0006886	Process	Intracellular protein transport	IDA	12606037
GO:0008104	Process	Intracellular protein localization	IEA
GO:0016020	Component	Membrane	IEA
GO:0019904	Function	Protein domain specific binding	IEA
GO:0032588	Component	Trans-Golgi network membrane	IBA
GO:0032588	Component	Trans-Golgi network membrane	IDA	23695357
GO:0032588	Component	Trans-Golgi network membrane	IEA
GO:0034315	Process	Regulation of Arp2/3 complex-mediated actin nucleation	IBA
GO:0050708	Process	Regulation of protein secretion	IDA	12606037
GO:0070273	Function	Phosphatidylinositol-4-phosphate binding	IDA	23695357
GO:0070273	Function	Phosphatidylinositol-4-phosphate binding	IEA
GO:1905280	Process	Negative regulation of retrograde transport, endosome to Golgi	IMP	25789876

Other IDs

• MIM: 605928
• HGNC: 21496
• e!Ensembl: ENSG00000164144

Protein

• UniProt ID: P53367
• Protein name: Arfaptin-1 (ADP-ribosylation factor-interacting protein 1)
• Protein function: Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network (PubMed:22981988). Mechanistically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold (PubMed:22981988, PubM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06456	Arfaptin	121 → 348	Arfaptin-like domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed (PubMed:9038142). Higher levels in liver, pancreas, placenta, skeletal muscle and heart (PubMed:9038142). {ECO:0000269|PubMed:9038142}.
• Sequence:

  MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV
  IEAGAFQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEIKNP
  AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ
  TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA
  SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH
  KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK
  TPGVDAPSWLEEQ

• Sequence length: 373

Related Genes

No strongly related genes found yet for ARFIP1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ARFIP1.