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Gene Gene information from NCBI Gene database.
Entrez ID 54851
Gene name Ankyrin repeat domain 49
Gene symbol ANKRD49
Synonyms (NCBI Gene)
FGIFGBIF
Chromosome 11
Chromosome location 11q21
miRNA miRNA information provided by mirtarbase database.
266 Show/Hide all (266)
miRTarBase ID miRNA Experiments Reference
MIRT437783 hsa-miR-342-3p MicroarrayqRT-PCR 23689423
MIRT437783 hsa-miR-342-3p MicroarrayqRT-PCR 23689423
MIRT525597 hsa-miR-105-5p PAR-CLIP 22012620
MIRT525595 hsa-miR-7853-5p PAR-CLIP 22012620
MIRT525596 hsa-miR-221-5p PAR-CLIP 22012620
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7 Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 17003112, 24855949, 25036637, 28514442, 29426014, 32296183, 33961781
GO:0005634 Component Nucleus IC 16131492
GO:0005634 Component Nucleus IEA
GO:0007283 Process Spermatogenesis IEA
GO:0030154 Process Cell differentiation IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
619571 25970 ENSG00000168876
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WVL7
Protein name Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor)
Protein function Induces HBG1 expression (PubMed:11162141, PubMed:16131492). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity). {ECO:0000250|UniProtKB:Q8VE42, ECO:0000269|Pub
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12796 Ank_2 78 → 171 Ankyrin repeats (3 copies) Repeat
PF13637 Ank_4 108 → 161 Repeat
PF13857 Ank_5 96 → 148 Repeat
Tissue specificity TISSUE SPECIFICITY: Widely expressed in fetus, at a high level in fetal liver, brain and lung. {ECO:0000269|PubMed:11162141}.
Sequence
MEKEKGNDDGIPDQENSLDFSEHFNQLELLETHGHLIPTGTQSLWVGNSDEDEEQDDKNE
EWYRLQEKKMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGH
LDIVQELIAQGADVHAVTVDGWTPLHSA
CKWNNTRVASFLL
QHDADINAQT
KGLLTPLHL
AAGNRDSKDTLELLLMNRYVKPGLKNNLEETAFDIARRTSIYHYLFEIVEGCTNSSPQS
Sequence length 239
Interactions View interactions