ANKRA2 (ankyrin repeat family A member 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57763
• Gene name: Ankyrin repeat family A member 2
• Gene symbol: ANKRA2
• Synonyms (NCBI Gene): ANKRA
• Chromosome: 5
• Chromosome location: 5q13.2

miRNA Show/Hide all (108)

miRTarBase ID	miRNA	Experiments	Reference
MIRT728346	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT728345	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT728344	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT728342	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT728343	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT782409	hsa-miR-30a	CLIP-seq
MIRT782410	hsa-miR-30b	CLIP-seq
MIRT782411	hsa-miR-30c	CLIP-seq
MIRT782412	hsa-miR-30d	CLIP-seq
MIRT782413	hsa-miR-30e	CLIP-seq
MIRT782414	hsa-miR-369-3p	CLIP-seq
MIRT782415	hsa-miR-374a	CLIP-seq
MIRT782416	hsa-miR-374b	CLIP-seq
MIRT782417	hsa-miR-4325	CLIP-seq
MIRT782418	hsa-miR-4705	CLIP-seq
MIRT782419	hsa-miR-889	CLIP-seq
MIRT782409	hsa-miR-30a	CLIP-seq
MIRT782410	hsa-miR-30b	CLIP-seq
MIRT782411	hsa-miR-30c	CLIP-seq
MIRT782412	hsa-miR-30d	CLIP-seq
MIRT782413	hsa-miR-30e	CLIP-seq
MIRT2171502	hsa-miR-4272	CLIP-seq
MIRT782417	hsa-miR-4325	CLIP-seq
MIRT782418	hsa-miR-4705	CLIP-seq
MIRT2474522	hsa-miR-101	CLIP-seq
MIRT2474523	hsa-miR-144	CLIP-seq
MIRT2474524	hsa-miR-25	CLIP-seq
MIRT782409	hsa-miR-30a	CLIP-seq
MIRT782410	hsa-miR-30b	CLIP-seq
MIRT782411	hsa-miR-30c	CLIP-seq
MIRT782412	hsa-miR-30d	CLIP-seq
MIRT782413	hsa-miR-30e	CLIP-seq
MIRT2474525	hsa-miR-3120-3p	CLIP-seq
MIRT2474526	hsa-miR-3132	CLIP-seq
MIRT2474527	hsa-miR-32	CLIP-seq
MIRT2474528	hsa-miR-363	CLIP-seq
MIRT2474529	hsa-miR-3647-3p	CLIP-seq
MIRT2474530	hsa-miR-367	CLIP-seq
MIRT2474531	hsa-miR-3682-3p	CLIP-seq
MIRT782415	hsa-miR-374a	CLIP-seq
MIRT782416	hsa-miR-374b	CLIP-seq
MIRT2474532	hsa-miR-374c	CLIP-seq
MIRT2474533	hsa-miR-3919	CLIP-seq
MIRT2474534	hsa-miR-4282	CLIP-seq
MIRT2474535	hsa-miR-4477a	CLIP-seq
MIRT2474536	hsa-miR-4499	CLIP-seq
MIRT2474537	hsa-miR-4502	CLIP-seq
MIRT2474538	hsa-miR-4650-3p	CLIP-seq
MIRT2474539	hsa-miR-4666-5p	CLIP-seq
MIRT2474540	hsa-miR-4699-5p	CLIP-seq
MIRT2474541	hsa-miR-4729	CLIP-seq
MIRT2474542	hsa-miR-4756-3p	CLIP-seq
MIRT2474543	hsa-miR-4762-3p	CLIP-seq
MIRT2474544	hsa-miR-4766-5p	CLIP-seq
MIRT2474545	hsa-miR-4775	CLIP-seq
MIRT2474546	hsa-miR-510	CLIP-seq
MIRT2474547	hsa-miR-512-5p	CLIP-seq
MIRT2474548	hsa-miR-520d-5p	CLIP-seq
MIRT2474549	hsa-miR-524-5p	CLIP-seq
MIRT2474550	hsa-miR-539	CLIP-seq
MIRT2474551	hsa-miR-548aa	CLIP-seq
MIRT2474552	hsa-miR-548ac	CLIP-seq
MIRT2474553	hsa-miR-548ae	CLIP-seq
MIRT2474554	hsa-miR-548aj	CLIP-seq
MIRT2474555	hsa-miR-548am	CLIP-seq
MIRT2474556	hsa-miR-548c-3p	CLIP-seq
MIRT2474557	hsa-miR-548d-3p	CLIP-seq
MIRT2474558	hsa-miR-548u	CLIP-seq
MIRT2474559	hsa-miR-548x	CLIP-seq
MIRT2474560	hsa-miR-548z	CLIP-seq
MIRT2474561	hsa-miR-570	CLIP-seq
MIRT2474562	hsa-miR-590-3p	CLIP-seq
MIRT2474563	hsa-miR-655	CLIP-seq
MIRT2474564	hsa-miR-891b	CLIP-seq
MIRT2474565	hsa-miR-92a	CLIP-seq
MIRT2474566	hsa-miR-92b	CLIP-seq
MIRT2474522	hsa-miR-101	CLIP-seq
MIRT2474523	hsa-miR-144	CLIP-seq
MIRT2474525	hsa-miR-3120-3p	CLIP-seq
MIRT2474526	hsa-miR-3132	CLIP-seq
MIRT2474529	hsa-miR-3647-3p	CLIP-seq
MIRT2474531	hsa-miR-3682-3p	CLIP-seq
MIRT782415	hsa-miR-374a	CLIP-seq
MIRT782416	hsa-miR-374b	CLIP-seq
MIRT2474532	hsa-miR-374c	CLIP-seq
MIRT2474533	hsa-miR-3919	CLIP-seq
MIRT2474534	hsa-miR-4282	CLIP-seq
MIRT2474535	hsa-miR-4477a	CLIP-seq
MIRT2474536	hsa-miR-4499	CLIP-seq
MIRT2474537	hsa-miR-4502	CLIP-seq
MIRT2474538	hsa-miR-4650-3p	CLIP-seq
MIRT2474539	hsa-miR-4666-5p	CLIP-seq
MIRT2474540	hsa-miR-4699-5p	CLIP-seq
MIRT2474542	hsa-miR-4756-3p	CLIP-seq
MIRT2474543	hsa-miR-4762-3p	CLIP-seq
MIRT2474544	hsa-miR-4766-5p	CLIP-seq
MIRT2474545	hsa-miR-4775	CLIP-seq
MIRT2474546	hsa-miR-510	CLIP-seq
MIRT2474547	hsa-miR-512-5p	CLIP-seq
MIRT2474548	hsa-miR-520d-5p	CLIP-seq
MIRT2474549	hsa-miR-524-5p	CLIP-seq
MIRT2474550	hsa-miR-539	CLIP-seq
MIRT2474551	hsa-miR-548aa	CLIP-seq
MIRT2474556	hsa-miR-548c-3p	CLIP-seq
MIRT2474558	hsa-miR-548u	CLIP-seq
MIRT2474561	hsa-miR-570	CLIP-seq
MIRT2474562	hsa-miR-590-3p	CLIP-seq
MIRT2474563	hsa-miR-655	CLIP-seq

Gene ontology (GO) Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 25752541, 31864703, 32296183, 35044719
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	11095640
GO:0005856	Component	Cytoskeleton	IEA
GO:0010468	Process	Regulation of gene expression	IBA
GO:0016020	Component	Membrane	IDA	11095640
GO:0016020	Component	Membrane	IEA
GO:0019901	Function	Protein kinase binding	IPI	20873783
GO:0031625	Function	Ubiquitin protein ligase binding	IDA	25752541
GO:0032991	Component	Protein-containing complex	IDA	20873783
GO:0042826	Function	Histone deacetylase binding	IDA	22649097
GO:0042826	Function	Histone deacetylase binding	IEA
GO:0042826	Function	Histone deacetylase binding	IPI	22649097
GO:0043254	Process	Regulation of protein-containing complex assembly	IDA	25752541
GO:0050750	Function	Low-density lipoprotein particle receptor binding	IPI	22649097
GO:1990393	Component	3M complex	IDA	25752541

Other IDs

• MIM: 605787
• HGNC: 13208
• e!Ensembl: ENSG00000164331

Protein

• UniProt ID: Q9H9E1
• Protein name: Ankyrin repeat family A protein 2 (RFXANK-like protein 2)
• Protein function: May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5 (PubMed:25752541). May also regulate LRP2/megalin (By similarity).
• PDB: 3SO8 , 3V2O , 3V2X , 3V31 , 4LG6 , 4QQI , 8CXG , 8CXH , 8CXI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	134 → 243	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	209 → 278	Ankyrin repeats (3 copies)	Repeat

• Sequence:

  MDTSTNLDIGAQLIVEECPSTYSLTGMPDIKIEHPLDPNSEEGSAQGVAMGMKFILPNRF
  DMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTT
  KHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDE
  EGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVD
  VNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAVALGYRSVQQVI
  ESHLLKLLQNIKE

• Sequence length: 313

Related Genes

No strongly related genes found yet for ANKRA2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ANKRA2.