AMIGO3 (adhesion molecule with Ig like domain 3)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 386724
• Gene name: Adhesion molecule with Ig like domain 3
• Gene symbol: AMIGO3
• Synonyms (NCBI Gene): ALI3, AMIGO-3
• Chromosome: 3
• Chromosome location: 3p21.31

miRNA Show/Hide all (63)

miRTarBase ID	miRNA	Experiments	Reference
MIRT779860	hsa-miR-15a	CLIP-seq
MIRT779861	hsa-miR-15b	CLIP-seq
MIRT779862	hsa-miR-16	CLIP-seq
MIRT779863	hsa-miR-193a-5p	CLIP-seq
MIRT779864	hsa-miR-195	CLIP-seq
MIRT779865	hsa-miR-2861	CLIP-seq
MIRT779866	hsa-miR-3127-3p	CLIP-seq
MIRT779867	hsa-miR-3179	CLIP-seq
MIRT779868	hsa-miR-424	CLIP-seq
MIRT779869	hsa-miR-451b	CLIP-seq
MIRT779870	hsa-miR-4649-5p	CLIP-seq
MIRT779871	hsa-miR-497	CLIP-seq
MIRT779872	hsa-miR-661	CLIP-seq
MIRT779866	hsa-miR-3127-3p	CLIP-seq
MIRT2170929	hsa-miR-3692	CLIP-seq
MIRT2473495	hsa-miR-1224-3p	CLIP-seq
MIRT2473496	hsa-miR-1260	CLIP-seq
MIRT2473497	hsa-miR-1260b	CLIP-seq
MIRT2473498	hsa-miR-1275	CLIP-seq
MIRT2473499	hsa-miR-1280	CLIP-seq
MIRT2473500	hsa-miR-1293	CLIP-seq
MIRT2473501	hsa-miR-1470	CLIP-seq
MIRT779865	hsa-miR-2861	CLIP-seq
MIRT2473502	hsa-miR-3189-3p	CLIP-seq
MIRT2473503	hsa-miR-4447	CLIP-seq
MIRT2473504	hsa-miR-4469	CLIP-seq
MIRT2473505	hsa-miR-4472	CLIP-seq
MIRT2473506	hsa-miR-4483	CLIP-seq
MIRT2473507	hsa-miR-4488	CLIP-seq
MIRT2473508	hsa-miR-4525	CLIP-seq
MIRT2473509	hsa-miR-4640-3p	CLIP-seq
MIRT2473510	hsa-miR-4665-5p	CLIP-seq
MIRT2473511	hsa-miR-4667-3p	CLIP-seq
MIRT2473512	hsa-miR-4697-5p	CLIP-seq
MIRT2473513	hsa-miR-4723-5p	CLIP-seq
MIRT2473514	hsa-miR-532-3p	CLIP-seq
MIRT2473515	hsa-miR-625	CLIP-seq
MIRT779872	hsa-miR-661	CLIP-seq
MIRT2473516	hsa-miR-939	CLIP-seq
MIRT2473495	hsa-miR-1224-3p	CLIP-seq
MIRT2473496	hsa-miR-1260	CLIP-seq
MIRT2473497	hsa-miR-1260b	CLIP-seq
MIRT2473498	hsa-miR-1275	CLIP-seq
MIRT2473499	hsa-miR-1280	CLIP-seq
MIRT2473500	hsa-miR-1293	CLIP-seq
MIRT2473501	hsa-miR-1470	CLIP-seq
MIRT779865	hsa-miR-2861	CLIP-seq
MIRT2473502	hsa-miR-3189-3p	CLIP-seq
MIRT2473503	hsa-miR-4447	CLIP-seq
MIRT2473504	hsa-miR-4469	CLIP-seq
MIRT2473505	hsa-miR-4472	CLIP-seq
MIRT2473506	hsa-miR-4483	CLIP-seq
MIRT2473507	hsa-miR-4488	CLIP-seq
MIRT2473508	hsa-miR-4525	CLIP-seq
MIRT2473509	hsa-miR-4640-3p	CLIP-seq
MIRT2473510	hsa-miR-4665-5p	CLIP-seq
MIRT2473511	hsa-miR-4667-3p	CLIP-seq
MIRT2473512	hsa-miR-4697-5p	CLIP-seq
MIRT2473513	hsa-miR-4723-5p	CLIP-seq
MIRT2473514	hsa-miR-532-3p	CLIP-seq
MIRT2473515	hsa-miR-625	CLIP-seq
MIRT779872	hsa-miR-661	CLIP-seq
MIRT2473516	hsa-miR-939	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0007155	Process	Cell adhesion	IEA
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IEA
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ISS	12629050
GO:0007399	Process	Nervous system development	IEA
GO:0007420	Process	Brain development	IBA
GO:0010977	Process	Negative regulation of neuron projection development	IEA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0051965	Process	Positive regulation of synapse assembly	IBA
GO:0051965	Process	Positive regulation of synapse assembly	IEA

Other IDs

• MIM: 615691
• HGNC: 24075
• e!Ensembl: ENSG00000176020

Protein

• UniProt ID: Q86WK7
• Protein name: Amphoterin-induced protein 3 (AMIGO-3) (Alivin-3)
• Protein function: May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	85 → 145	Leucine rich repeat	Repeat
  PF13855	LRR_8	134 → 195	Leucine rich repeat	Repeat
  PF13855	LRR_8	61 → 97	Leucine rich repeat	Repeat

• Sequence:

  MTWLVLLGTLLCMLRVGLGTPDSEGFPPRALHNCPYKCICAADLLSCTGLGLQDVPAELP
  AATADLDLSHNALQRLRPGWLAPLFQLRALHLDHNELDALGRGVFVNASGLRLLDLSSNT
  LRALGRHDLDGLGALEKLLLFNNRLVHLDEHAFHGLRALSHLYLGCNELASFSFDHLHGL
  SATHLLTLDLSSNRLGHISVPELAALPAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLS
  AVRDFAREYVCLAFKVPASRVRFFQHSRVFENCSSAPALGLERPEEHLYALVGRSLRLYC
  NTSVPAMRIAWVSPQQELLRAPGSRDGSIAVLADGSLAIGNVQEQHAGLFVCLATGPRLH
  HNQTHEYNVSVHFPRPEPEAFNTGFTTLLGCAVGLVLVLLYLFAPPCRCCRRACRCRRWP
  QTPSPLQELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEEFDLYN
  PGGLQLKAGSESASSIGSEGPMTT

• Sequence length: 504

Related Genes

No strongly related genes found yet for AMIGO3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to AMIGO3.