AKAP17A (A-kinase anchoring protein 17A)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 8227
• Gene name: A-kinase anchoring protein 17A
• Gene symbol: AKAP17A
• Synonyms (NCBI Gene): 721P, AKAP-17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y
• Chromosome: X|Y
• Chromosome location: X;Y
• Summary: This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified

miRNA Show/Hide all (105)

miRTarBase ID	miRNA	Experiments	Reference
MIRT052445	hsa-let-7a-5p	CLASH	23622248
MIRT230192	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT230188	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT230190	hsa-miR-3609	PAR-CLIP	20371350
MIRT230191	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT230185	hsa-miR-33a-3p	PAR-CLIP	20371350
MIRT230189	hsa-miR-4307	PAR-CLIP	20371350
MIRT563932	hsa-miR-1252-5p	PAR-CLIP	20371350
MIRT563931	hsa-miR-4711-5p	PAR-CLIP	20371350
MIRT230187	hsa-miR-1257	PAR-CLIP	20371350
MIRT563930	hsa-miR-6126	PAR-CLIP	20371350
MIRT563929	hsa-miR-6864-5p	PAR-CLIP	20371350
MIRT530302	hsa-miR-148a-3p	PAR-CLIP	22012620
MIRT530301	hsa-miR-148b-3p	PAR-CLIP	22012620
MIRT530300	hsa-miR-152-3p	PAR-CLIP	22012620
MIRT530299	hsa-miR-4302	PAR-CLIP	22012620
MIRT530298	hsa-miR-199a-5p	PAR-CLIP	22012620
MIRT530297	hsa-miR-199b-5p	PAR-CLIP	22012620
MIRT530296	hsa-miR-627-3p	PAR-CLIP	22012620
MIRT530295	hsa-miR-134-5p	PAR-CLIP	22012620
MIRT530294	hsa-miR-3118	PAR-CLIP	22012620
MIRT530293	hsa-miR-3164	PAR-CLIP	22012620
MIRT530292	hsa-miR-6820-3p	PAR-CLIP	22012620
MIRT530291	hsa-miR-4276	PAR-CLIP	22012620
MIRT530290	hsa-miR-30a-3p	PAR-CLIP	22012620
MIRT530289	hsa-miR-30d-3p	PAR-CLIP	22012620
MIRT530288	hsa-miR-30e-3p	PAR-CLIP	22012620
MIRT230192	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT230188	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT230190	hsa-miR-3609	PAR-CLIP	20371350
MIRT230191	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT230185	hsa-miR-33a-3p	PAR-CLIP	20371350
MIRT230189	hsa-miR-4307	PAR-CLIP	20371350
MIRT563932	hsa-miR-1252-5p	PAR-CLIP	20371350
MIRT563931	hsa-miR-4711-5p	PAR-CLIP	20371350
MIRT230187	hsa-miR-1257	PAR-CLIP	20371350
MIRT563930	hsa-miR-6126	PAR-CLIP	20371350
MIRT563929	hsa-miR-6864-5p	PAR-CLIP	20371350
MIRT530302	hsa-miR-148a-3p	PAR-CLIP	22012620
MIRT530301	hsa-miR-148b-3p	PAR-CLIP	22012620
MIRT530300	hsa-miR-152-3p	PAR-CLIP	22012620
MIRT530299	hsa-miR-4302	PAR-CLIP	22012620
MIRT530298	hsa-miR-199a-5p	PAR-CLIP	22012620
MIRT530297	hsa-miR-199b-5p	PAR-CLIP	22012620
MIRT530296	hsa-miR-627-3p	PAR-CLIP	22012620
MIRT530295	hsa-miR-134-5p	PAR-CLIP	22012620
MIRT530294	hsa-miR-3118	PAR-CLIP	22012620
MIRT530293	hsa-miR-3164	PAR-CLIP	22012620
MIRT530292	hsa-miR-6820-3p	PAR-CLIP	22012620
MIRT530291	hsa-miR-4276	PAR-CLIP	22012620
MIRT530290	hsa-miR-30a-3p	PAR-CLIP	22012620
MIRT530289	hsa-miR-30d-3p	PAR-CLIP	22012620
MIRT530288	hsa-miR-30e-3p	PAR-CLIP	22012620
MIRT1928886	hsa-miR-1200	CLIP-seq
MIRT1928887	hsa-miR-1224-3p	CLIP-seq
MIRT1928888	hsa-miR-1260	CLIP-seq
MIRT1928889	hsa-miR-1260b	CLIP-seq
MIRT1928890	hsa-miR-1280	CLIP-seq
MIRT1928891	hsa-miR-2052	CLIP-seq
MIRT1928892	hsa-miR-3065-3p	CLIP-seq
MIRT1928893	hsa-miR-3133	CLIP-seq
MIRT1928894	hsa-miR-3143	CLIP-seq
MIRT1928895	hsa-miR-3194-3p	CLIP-seq
MIRT1928896	hsa-miR-323-3p	CLIP-seq
MIRT1928897	hsa-miR-324-5p	CLIP-seq
MIRT1928898	hsa-miR-383	CLIP-seq
MIRT1928899	hsa-miR-4304	CLIP-seq
MIRT1928900	hsa-miR-4325	CLIP-seq
MIRT1928901	hsa-miR-4485	CLIP-seq
MIRT1928902	hsa-miR-4660	CLIP-seq
MIRT1928903	hsa-miR-4727-5p	CLIP-seq
MIRT1928904	hsa-miR-4769-3p	CLIP-seq
MIRT1928905	hsa-miR-4772-5p	CLIP-seq
MIRT1928906	hsa-miR-4793-3p	CLIP-seq
MIRT1928907	hsa-miR-543	CLIP-seq
MIRT1928908	hsa-miR-646	CLIP-seq
MIRT1928909	hsa-miR-935	CLIP-seq
MIRT2169620	hsa-miR-186	CLIP-seq
MIRT2169621	hsa-miR-3124-3p	CLIP-seq
MIRT1928893	hsa-miR-3133	CLIP-seq
MIRT2169622	hsa-miR-3153	CLIP-seq
MIRT1928896	hsa-miR-323-3p	CLIP-seq
MIRT2169623	hsa-miR-3591-3p	CLIP-seq
MIRT2169624	hsa-miR-3685	CLIP-seq
MIRT2169625	hsa-miR-384	CLIP-seq
MIRT1928901	hsa-miR-4485	CLIP-seq
MIRT2169626	hsa-miR-520d-5p	CLIP-seq
MIRT2169627	hsa-miR-523	CLIP-seq
MIRT2169628	hsa-miR-524-5p	CLIP-seq
MIRT2169629	hsa-miR-625	CLIP-seq
MIRT1928891	hsa-miR-2052	CLIP-seq
MIRT1928893	hsa-miR-3133	CLIP-seq
MIRT1928901	hsa-miR-4485	CLIP-seq
MIRT1928891	hsa-miR-2052	CLIP-seq
MIRT1928892	hsa-miR-3065-3p	CLIP-seq
MIRT1928893	hsa-miR-3133	CLIP-seq
MIRT2472248	hsa-miR-3667-3p	CLIP-seq
MIRT1928899	hsa-miR-4304	CLIP-seq
MIRT1928901	hsa-miR-4485	CLIP-seq
MIRT2472249	hsa-miR-4724-3p	CLIP-seq
MIRT2674831	hsa-miR-331-5p	CLIP-seq
MIRT2674832	hsa-miR-4303	CLIP-seq
MIRT2674833	hsa-miR-4678	CLIP-seq
MIRT2674834	hsa-miR-4762-3p	CLIP-seq
MIRT2169627	hsa-miR-523	CLIP-seq

Gene ontology (GO) Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	16982639, 25416956, 31515488, 32296183, 39251607
GO:0005634	Component	Nucleus	IDA	19840947
GO:0005634	Component	Nucleus	IEA
GO:0005681	Component	Spliceosomal complex	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	1438229
GO:0006397	Process	MRNA processing	IEA
GO:0007165	Process	Signal transduction	NAS	1438229
GO:0008380	Process	RNA splicing	IEA
GO:0016607	Component	Nuclear speck	IBA
GO:0016607	Component	Nuclear speck	IDA	16982639
GO:0016607	Component	Nuclear speck	IEA
GO:0042113	Process	B cell activation	NAS	1438229
GO:0043484	Process	Regulation of RNA splicing	IBA
GO:0043484	Process	Regulation of RNA splicing	IMP	19840947
GO:0051018	Function	Protein kinase A binding	IBA
GO:0051018	Function	Protein kinase A binding	IDA	19840947

Other IDs

• MIM: 312095
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q02040
• Protein name: A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)
• Protein function: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells. {ECO:0000269|PubM
• Sequence:

  MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALPQLKQPGKSISNWEVMERLKGMVQ
  NHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKID
  FPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALKESGSEKPSEDVLVKVFEK
  FGEIRNVDIPMLDPYREEMTGRNFHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLM
  YKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQR
  AEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEE
  RKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEE
  KERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVS
  ATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEK
  RCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHK
  RERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERS
  RERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR

• Sequence length: 695

Related Genes

No strongly related genes found yet for AKAP17A.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to AKAP17A.