AGAP6 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 6)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 414189
• Gene name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 6
• Gene symbol: AGAP6
• Synonyms (NCBI Gene): AGAP-6, CTGLF3
• Chromosome: 10
• Chromosome location: 10q11.23

miRNA Show/Hide all (30)

miRTarBase ID	miRNA	Experiments	Reference
MIRT2471133	hsa-miR-1278	CLIP-seq
MIRT2471134	hsa-miR-2113	CLIP-seq
MIRT2471135	hsa-miR-298	CLIP-seq
MIRT2471136	hsa-miR-3163	CLIP-seq
MIRT2471137	hsa-miR-3647-3p	CLIP-seq
MIRT2471138	hsa-miR-3672	CLIP-seq
MIRT2471139	hsa-miR-4699-3p	CLIP-seq
MIRT2471140	hsa-miR-4724-5p	CLIP-seq
MIRT2471141	hsa-miR-495	CLIP-seq
MIRT2471142	hsa-miR-548c-3p	CLIP-seq
MIRT2471143	hsa-miR-548k	CLIP-seq
MIRT2471144	hsa-miR-548n	CLIP-seq
MIRT2471145	hsa-miR-584	CLIP-seq
MIRT2471146	hsa-miR-599	CLIP-seq
MIRT2471133	hsa-miR-1278	CLIP-seq
MIRT2471134	hsa-miR-2113	CLIP-seq
MIRT2471135	hsa-miR-298	CLIP-seq
MIRT2471136	hsa-miR-3163	CLIP-seq
MIRT2471137	hsa-miR-3647-3p	CLIP-seq
MIRT2471138	hsa-miR-3672	CLIP-seq
MIRT2674690	hsa-miR-4680-3p	CLIP-seq
MIRT2471139	hsa-miR-4699-3p	CLIP-seq
MIRT2471140	hsa-miR-4724-5p	CLIP-seq
MIRT2471141	hsa-miR-495	CLIP-seq
MIRT2471142	hsa-miR-548c-3p	CLIP-seq
MIRT2471143	hsa-miR-548k	CLIP-seq
MIRT2471144	hsa-miR-548n	CLIP-seq
MIRT2471145	hsa-miR-584	CLIP-seq
MIRT2471146	hsa-miR-599	CLIP-seq
MIRT2674691	hsa-miR-758	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003924	Function	GTPase activity	IBA
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 621157
• HGNC: 23466
• e!Ensembl: ENSG00000204149

Protein

• UniProt ID: Q5VW22
• Protein name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6 (AGAP-6) (Centaurin-gamma-like family member 3)
• Protein function: Putative GTPase-activating protein.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01412	ArfGap	441 → 557	Putative GTPase activating protein for Arf	Domain
  PF12796	Ank_2	568 → 661	Ankyrin repeats (3 copies)	Repeat

• Sequence:

  MGNILTCRVHPSVSLEFDQQQGSVCPSESETYEAGARDRMAGAPMAAAVQPAEVTVEVGE
  DLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSAVRFSQQYS
  LCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRTLSIPDEQLHSFAVSTVHIMK
  KRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPD
  KERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGMLTYYSSLGDYM
  KNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSKSNGLSKDMDTGLGDSICFSPSISS
  TTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQIL
  ASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECS
  GIHRSLGPHLSRVRSLELDDWPVELRKVMSSIVNDLANSIWEGSSQGQTKPSEKSTREEK
  ERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSCEEVNETCGEGD
  GCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPD
  ECV

• Sequence length: 663

Pathways

KEGG Pathway:

Endocytosis

Related Genes

No strongly related genes found yet for AGAP6.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to AGAP6.