Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	142827
Gene name	Acyl-CoA synthetase medium chain family member 6
Gene symbol	ACSM6
Synonyms (NCBI Gene)	C10orf129bA310E22.3
Chromosome	10
Chromosome location	10q23.33

16 Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004321	Function	Fatty-acyl-CoA synthase activity	IBA
GO:0005524	Function	ATP binding	IEA
GO:0005525	Function	GTP binding	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005759	Component	Mitochondrial matrix	IBA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IBA
GO:0006637	Process	Acyl-CoA metabolic process	IBA
GO:0015645	Function	Fatty acid ligase activity	IBA
GO:0016874	Function	Ligase activity	IEA
GO:0016877	Function	Ligase activity, forming carbon-sulfur bonds	IEA
GO:0031956	Function	Medium-chain fatty acid-CoA ligase activity	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q6P461

Protein name

Acyl-coenzyme A synthetase ACSM6, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 6)

Protein function

Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00501	AMP-binding	68 → 475	AMP-binding enzyme	Family

Sequence

MLGRFQPFSLVRSFRLGFEACCYPNQKCATQTIRPPDSRCLVQAVSQNFNFAKDVLDQWS
QLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPP
TPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCP
TLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQ
YGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPE
TVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDWKRIT
KLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPPGEEGNIAIR
IKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFWWSGRVDDVANALGQRL

Sequence length

480

Interactions

View interactions

KEGG Pathway
Butanoate metabolism
Metabolic pathways

Related Genes Genes most often co-reported with ACSM6 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for ACSM6.

Diseases Linked via Similar Genes Diseases curated for genes most similar to ACSM6 (see Related Genes above), that are NOT already directly curated for ACSM6 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to ACSM6.

ACSM6 (acyl-CoA synthetase medium chain family member 6)

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