ACOT13 (acyl-CoA thioesterase 13)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55856 |
| Gene name | Acyl-CoA thioesterase 13 |
| Gene symbol | ACOT13 |
| Synonyms (NCBI Gene) |
HT012PNAS-27THEM2
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| Chromosome | 6 |
| Chromosome location | 6p22.3 |
| Summary | This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. Th |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NPJ3 | ||||||||||
| Protein name | Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Hotdog-fold thioesterase superfamily member 2) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Thioesterase superfamily member 2) (THEM2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-te | ||||||||||
| Protein function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545). Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) | ||||||||||
| PDB | 2F0X , 2H4U , 3F5O | ||||||||||
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Pfam
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| Sequence |
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| Sequence length | 140 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with ACOT13 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to ACOT13 (see Related Genes above), that are NOT already directly curated for ACOT13 itself -- a lead worth checking, not a confirmed association.
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