ACAP3 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 3)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 116983
• Gene name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
• Gene symbol: ACAP3
• Synonyms (NCBI Gene): CENTB5
• Chromosome: 1
• Chromosome location: 1p36.33

miRNA Show/Hide all (57)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050700	hsa-miR-18a-5p	CLASH	23622248
MIRT761852	hsa-miR-1266	CLIP-seq
MIRT761853	hsa-miR-1275	CLIP-seq
MIRT761854	hsa-miR-1285	CLIP-seq
MIRT761855	hsa-miR-1286	CLIP-seq
MIRT761856	hsa-miR-298	CLIP-seq
MIRT761857	hsa-miR-3151	CLIP-seq
MIRT761858	hsa-miR-3187-5p	CLIP-seq
MIRT761859	hsa-miR-378g	CLIP-seq
MIRT761860	hsa-miR-3936	CLIP-seq
MIRT761861	hsa-miR-3944-5p	CLIP-seq
MIRT761862	hsa-miR-4259	CLIP-seq
MIRT761863	hsa-miR-4290	CLIP-seq
MIRT761864	hsa-miR-4314	CLIP-seq
MIRT761865	hsa-miR-4419a	CLIP-seq
MIRT761866	hsa-miR-4455	CLIP-seq
MIRT761867	hsa-miR-4459	CLIP-seq
MIRT761868	hsa-miR-4486	CLIP-seq
MIRT761869	hsa-miR-4510	CLIP-seq
MIRT761870	hsa-miR-4518	CLIP-seq
MIRT761871	hsa-miR-4665-5p	CLIP-seq
MIRT761872	hsa-miR-4722-5p	CLIP-seq
MIRT761873	hsa-miR-4738-5p	CLIP-seq
MIRT761874	hsa-miR-4779	CLIP-seq
MIRT761875	hsa-miR-4795-5p	CLIP-seq
MIRT761876	hsa-miR-486-3p	CLIP-seq
MIRT761877	hsa-miR-571	CLIP-seq
MIRT761878	hsa-miR-612	CLIP-seq
MIRT1924626	hsa-miR-103a	CLIP-seq
MIRT1924627	hsa-miR-107	CLIP-seq
MIRT1924628	hsa-miR-1225-3p	CLIP-seq
MIRT1924629	hsa-miR-1915	CLIP-seq
MIRT1924630	hsa-miR-1972	CLIP-seq
MIRT1924631	hsa-miR-3065-3p	CLIP-seq
MIRT1924632	hsa-miR-361-3p	CLIP-seq
MIRT1924633	hsa-miR-4258	CLIP-seq
MIRT1924634	hsa-miR-4749-3p	CLIP-seq
MIRT2165901	hsa-miR-1224-5p	CLIP-seq
MIRT2165902	hsa-miR-214	CLIP-seq
MIRT2165903	hsa-miR-2355-5p	CLIP-seq
MIRT2165904	hsa-miR-3126-5p	CLIP-seq
MIRT2165905	hsa-miR-342-5p	CLIP-seq
MIRT2165906	hsa-miR-3619-5p	CLIP-seq
MIRT761865	hsa-miR-4419a	CLIP-seq
MIRT2165907	hsa-miR-4446-3p	CLIP-seq
MIRT761868	hsa-miR-4486	CLIP-seq
MIRT761869	hsa-miR-4510	CLIP-seq
MIRT2165908	hsa-miR-4651	CLIP-seq
MIRT2165909	hsa-miR-4656	CLIP-seq
MIRT2165910	hsa-miR-4664-5p	CLIP-seq
MIRT2165911	hsa-miR-4685-5p	CLIP-seq
MIRT2165912	hsa-miR-4710	CLIP-seq
MIRT2165913	hsa-miR-4726-3p	CLIP-seq
MIRT2165914	hsa-miR-4751	CLIP-seq
MIRT761876	hsa-miR-486-3p	CLIP-seq
MIRT2165915	hsa-miR-608	CLIP-seq
MIRT2165916	hsa-miR-761	CLIP-seq

Gene ontology (GO) Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001764	Process	Neuron migration	IEA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005515	Function	Protein binding	IPI	33961781, 35271311
GO:0005737	Component	Cytoplasm	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010975	Process	Regulation of neuron projection development	IEA
GO:0030426	Component	Growth cone	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96P50
• Protein name: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (Centaurin-beta-5) (Cnt-b5)
• Protein function: GTPase-activating protein for the ADP ribosylation factor family.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00169	PH	269 → 363	PH domain	Domain
  PF01412	ArfGap	403 → 521	Putative GTPase activating protein for Arf	Domain
  PF13857	Ank_5	687 → 743		Repeat
  PF16746	BAR_3	3 → 236		Domain

• Sequence:

  MTVEFEECVKDSPRFRATIDEVETDVVEIEAKLDKLVKLCSGMVEAGKAYVSTSRLFVSG
  VRDLSQQCQGDTVISECLQRFADSLQEVVNYHMILFDQAQRSVRQQLQSFVKEDVRKFKE
  TKKQFDKVREDLELSLVRNAQAPRHRPHEVEEATGALTLTRKCFRHLALDYVLQINVLQA
  KKKFEILDSMLSFMHAQSSFFQQGYSLLHQLDPYMKKLAAELDQLVIDSAVEKREMERKH
  AAIQQRTLLQDFSYDESKVEFDVDAPSGVVMEGYLFKRASNAFKTWNRRWFSIQNSQLVY
  QKKLKDALTVVVDDLRLCSVKPCEDIERRFCFEVLSPTKSCMLQADSEKLRQAWVQAVQA
  SIASAYRESPDSCYSERLDRTASPSTSSIDSATDTRERGVKGESVLQRVQSVAGNSQCGD
  CGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWEPELLKLMCELGNSAVN
  QIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPMAPALEAPRRWRVQKCLR
  PHSSPRAPTARRKVRLEPVLPCVAALSSVGTLDRKFRRDSLFCPDELDSLFSYFDAGAAG
  AGPRSLSSDSGLGGSSDGSSDVLAFGSGSVVDSVTEEEGAESEESSGEADGDTEAEAWGL
  ADVRELHPGLLAHRAARARDLPALAAALAHGAEVNWADAEDEGKTPLVQAVLGGSLIVCE
  FLLQNGADVNQRDSRGRAPLHHATLLGRTGQVCLFLKRGADQHALDQEQRDPLAIAVQAA
  NADIVTLLRLARMAEEMREAEAAPGPPGALAGSPTELQFRRCIQEFISLHLEES

• Sequence length: 834

Pathways

KEGG Pathway:

Endocytosis

Related Genes

No strongly related genes found yet for ACAP3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to ACAP3.