AARSD1 (alanyl-tRNA synthetase domain containing 1)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 80755
• Gene name: Alanyl-tRNA synthetase domain containing 1
• Gene symbol: AARSD1
• Synonyms (NCBI Gene): AlaXp
• Chromosome: 17
• Chromosome location: 17q21.31

miRNA Show/Hide all (112)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001655	hsa-let-7b-5p	pSILAC	18668040
MIRT001655	hsa-let-7b-5p	Proteomics;Other	18668040
MIRT757402	hsa-miR-1253	CLIP-seq
MIRT757403	hsa-miR-1273	CLIP-seq
MIRT757404	hsa-miR-28-3p	CLIP-seq
MIRT757405	hsa-miR-3188	CLIP-seq
MIRT757406	hsa-miR-3917	CLIP-seq
MIRT757407	hsa-miR-409-5p	CLIP-seq
MIRT757408	hsa-miR-4419a	CLIP-seq
MIRT757409	hsa-miR-4432	CLIP-seq
MIRT757410	hsa-miR-4434	CLIP-seq
MIRT757411	hsa-miR-4486	CLIP-seq
MIRT757412	hsa-miR-4510	CLIP-seq
MIRT757413	hsa-miR-4516	CLIP-seq
MIRT757414	hsa-miR-451b	CLIP-seq
MIRT757415	hsa-miR-4649-5p	CLIP-seq
MIRT757416	hsa-miR-4696	CLIP-seq
MIRT757417	hsa-miR-508-5p	CLIP-seq
MIRT757418	hsa-miR-661	CLIP-seq
MIRT757419	hsa-miR-766	CLIP-seq
MIRT757420	hsa-miR-1273e	CLIP-seq
MIRT757421	hsa-miR-1276	CLIP-seq
MIRT757422	hsa-miR-1293	CLIP-seq
MIRT757423	hsa-miR-1827	CLIP-seq
MIRT757424	hsa-miR-1912	CLIP-seq
MIRT757425	hsa-miR-2114	CLIP-seq
MIRT757426	hsa-miR-24	CLIP-seq
MIRT757427	hsa-miR-2964a-3p	CLIP-seq
MIRT757428	hsa-miR-302f	CLIP-seq
MIRT757429	hsa-miR-3122	CLIP-seq
MIRT757430	hsa-miR-3165	CLIP-seq
MIRT757431	hsa-miR-3689a-3p	CLIP-seq
MIRT757432	hsa-miR-3689c	CLIP-seq
MIRT757433	hsa-miR-3689d	CLIP-seq
MIRT757434	hsa-miR-380	CLIP-seq
MIRT757435	hsa-miR-3913-5p	CLIP-seq
MIRT757436	hsa-miR-3929	CLIP-seq
MIRT757437	hsa-miR-4284	CLIP-seq
MIRT757438	hsa-miR-4311	CLIP-seq
MIRT757439	hsa-miR-4419b	CLIP-seq
MIRT757440	hsa-miR-4455	CLIP-seq
MIRT757441	hsa-miR-4478	CLIP-seq
MIRT757442	hsa-miR-4483	CLIP-seq
MIRT757443	hsa-miR-4649-3p	CLIP-seq
MIRT757444	hsa-miR-4666-5p	CLIP-seq
MIRT757445	hsa-miR-4722-5p	CLIP-seq
MIRT757446	hsa-miR-4728-5p	CLIP-seq
MIRT757447	hsa-miR-4768-3p	CLIP-seq
MIRT757448	hsa-miR-485-3p	CLIP-seq
MIRT757449	hsa-miR-485-5p	CLIP-seq
MIRT757450	hsa-miR-500a	CLIP-seq
MIRT757451	hsa-miR-583	CLIP-seq
MIRT757452	hsa-miR-890	CLIP-seq
MIRT757453	hsa-miR-940	CLIP-seq
MIRT757422	hsa-miR-1293	CLIP-seq
MIRT757429	hsa-miR-3122	CLIP-seq
MIRT757430	hsa-miR-3165	CLIP-seq
MIRT757431	hsa-miR-3689a-3p	CLIP-seq
MIRT757432	hsa-miR-3689c	CLIP-seq
MIRT757434	hsa-miR-380	CLIP-seq
MIRT757435	hsa-miR-3913-5p	CLIP-seq
MIRT757436	hsa-miR-3929	CLIP-seq
MIRT757439	hsa-miR-4419b	CLIP-seq
MIRT757441	hsa-miR-4478	CLIP-seq
MIRT757442	hsa-miR-4483	CLIP-seq
MIRT757444	hsa-miR-4666-5p	CLIP-seq
MIRT757446	hsa-miR-4728-5p	CLIP-seq
MIRT757447	hsa-miR-4768-3p	CLIP-seq
MIRT757448	hsa-miR-485-3p	CLIP-seq
MIRT757449	hsa-miR-485-5p	CLIP-seq
MIRT757450	hsa-miR-500a	CLIP-seq
MIRT757403	hsa-miR-1273	CLIP-seq
MIRT757422	hsa-miR-1293	CLIP-seq
MIRT757429	hsa-miR-3122	CLIP-seq
MIRT2164835	hsa-miR-3130-3p	CLIP-seq
MIRT757430	hsa-miR-3165	CLIP-seq
MIRT757431	hsa-miR-3689a-3p	CLIP-seq
MIRT757432	hsa-miR-3689c	CLIP-seq
MIRT757434	hsa-miR-380	CLIP-seq
MIRT757435	hsa-miR-3913-5p	CLIP-seq
MIRT757436	hsa-miR-3929	CLIP-seq
MIRT757439	hsa-miR-4419b	CLIP-seq
MIRT757409	hsa-miR-4432	CLIP-seq
MIRT2164836	hsa-miR-4433	CLIP-seq
MIRT2164837	hsa-miR-4459	CLIP-seq
MIRT757441	hsa-miR-4478	CLIP-seq
MIRT757442	hsa-miR-4483	CLIP-seq
MIRT757411	hsa-miR-4486	CLIP-seq
MIRT757414	hsa-miR-451b	CLIP-seq
MIRT757415	hsa-miR-4649-5p	CLIP-seq
MIRT757444	hsa-miR-4666-5p	CLIP-seq
MIRT757416	hsa-miR-4696	CLIP-seq
MIRT757446	hsa-miR-4728-5p	CLIP-seq
MIRT757447	hsa-miR-4768-3p	CLIP-seq
MIRT2164838	hsa-miR-4786-5p	CLIP-seq
MIRT2164839	hsa-miR-4793-3p	CLIP-seq
MIRT757449	hsa-miR-485-5p	CLIP-seq
MIRT757450	hsa-miR-500a	CLIP-seq
MIRT757417	hsa-miR-508-5p	CLIP-seq
MIRT757418	hsa-miR-661	CLIP-seq
MIRT757419	hsa-miR-766	CLIP-seq
MIRT2164840	hsa-miR-767-5p	CLIP-seq
MIRT2466644	hsa-miR-1914	CLIP-seq
MIRT2466645	hsa-miR-3190	CLIP-seq
MIRT757433	hsa-miR-3689d	CLIP-seq
MIRT2466646	hsa-miR-4261	CLIP-seq
MIRT2164837	hsa-miR-4459	CLIP-seq
MIRT2466644	hsa-miR-1914	CLIP-seq
MIRT2466645	hsa-miR-3190	CLIP-seq
MIRT757433	hsa-miR-3689d	CLIP-seq
MIRT2466646	hsa-miR-4261	CLIP-seq
MIRT2164837	hsa-miR-4459	CLIP-seq

Gene ontology (GO) Show/Hide all (20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002161	Function	Aminoacyl-tRNA deacylase activity	IEA
GO:0002196	Function	Ser-tRNA(Ala) deacylase activity	IBA
GO:0002196	Function	Ser-tRNA(Ala) deacylase activity	IEA
GO:0003674	Function	Molecular_function	ND
GO:0003676	Function	Nucleic acid binding	IEA
GO:0004812	Function	Aminoacyl-tRNA ligase activity	IEA
GO:0004813	Function	Alanine-tRNA ligase activity	IEA
GO:0005515	Function	Protein binding	IPI	25036637, 28514442, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005737	Component	Cytoplasm	IEA
GO:0006412	Process	Translation	IEA
GO:0006419	Process	Alanyl-tRNA aminoacylation	IEA
GO:0006450	Process	Regulation of translational fidelity	IBA
GO:0006450	Process	Regulation of translational fidelity	IEA
GO:0008150	Process	Biological_process	ND
GO:0043039	Process	TRNA aminoacylation	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0106074	Process	Aminoacyl-tRNA metabolism involved in translational fidelity	IEA

Other IDs

• MIM: 613212
• HGNC: 28417
• e!Ensembl: ENSG00000266967

Protein

• UniProt ID: Q9BTE6
• Protein name: Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1)
• Protein function: Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07973	tRNA_SAD	196 → 241	Threonyl and Alanyl tRNA synthetase second additional domain	Domain

• Sequence:

  MAFWCQRDSYAREFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDD
  RGTINDISVLRVTRRGEQADHFTQTPLDPGSQVLVRVDWERRFDHMQQHSGQHLITAVAD
  HLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEV
  EQVSGRGLPDDHAGPIRVVNIEGVDSNMCCGTHVSNLSDLQVIKILGTEKGKKNRTNLIF
  LSGNRVLKWMERSHGTEKALTALLKCGAEDHVEAVKKLQNSTKILQKNNLNLLRDLAVHI
  AHSLRNSPDWGGVVILHRKEGDSEFMNIIANEIGSEETLLFLTVGDEKGGGLFLLAGPPA
  SVETLGPRVAEVLEGKGAGKKGRFQGKATKMSRRMEAQALLQDYISTQSAKE

• Sequence length: 412

Related Genes

No strongly related genes found yet for AARSD1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to AARSD1.