HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1)

Gene

• Entrez ID: 9957
• Gene name: Heparan sulfate-glucosamine 3-sulfotransferase 1
• Gene symbol: HS3ST1
• Synonyms (NCBI Gene): 3OST, 3OST1
• Chromosome: 4
• Chromosome location: 4p15.33
• Summary: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs16881446	T>C	Risk-factor	Intron variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT715339	hsa-miR-6801-3p	HITS-CLIP	19536157
MIRT715338	hsa-miR-6810-3p	HITS-CLIP	19536157
MIRT627148	hsa-miR-6075	HITS-CLIP	19536157
MIRT715337	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT715336	hsa-miR-4313	HITS-CLIP	19536157
MIRT686175	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686174	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686173	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686172	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686171	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686170	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686169	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686168	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686167	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686166	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686165	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686164	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686163	hsa-miR-302e	HITS-CLIP	23313552
MIRT686162	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686161	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686160	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686159	hsa-miR-520b	HITS-CLIP	23313552
MIRT686158	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686157	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686156	hsa-miR-520e	HITS-CLIP	23313552
MIRT686155	hsa-miR-4438	HITS-CLIP	23313552
MIRT702802	hsa-miR-941	HITS-CLIP	23313552
MIRT686154	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686153	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT686152	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT686151	hsa-miR-520h	HITS-CLIP	23313552
MIRT686150	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686149	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT702801	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT702800	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT686148	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686147	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686146	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT686145	hsa-miR-5095	HITS-CLIP	23313552
MIRT686144	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT686143	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT686142	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686141	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT686175	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686174	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686173	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686172	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686171	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686170	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686169	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686168	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686167	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686166	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686165	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686164	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686163	hsa-miR-302e	HITS-CLIP	23313552
MIRT686162	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686161	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686160	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686159	hsa-miR-520b	HITS-CLIP	23313552
MIRT686158	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686157	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686156	hsa-miR-520e	HITS-CLIP	23313552
MIRT686155	hsa-miR-4438	HITS-CLIP	23313552
MIRT686154	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686153	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT686152	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT686151	hsa-miR-520h	HITS-CLIP	23313552
MIRT686150	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686149	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT686148	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686147	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686146	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT686145	hsa-miR-5095	HITS-CLIP	23313552
MIRT686144	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT686143	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT686142	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686141	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT627149	hsa-miR-5693	HITS-CLIP	23824327
MIRT627148	hsa-miR-6075	HITS-CLIP	23824327
MIRT627147	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627146	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627145	hsa-miR-1267	HITS-CLIP	23824327
MIRT627144	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT627143	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT638075	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT627142	hsa-miR-3135b	HITS-CLIP	23824327
MIRT627141	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT627140	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT627139	hsa-miR-3652	HITS-CLIP	23824327
MIRT627138	hsa-miR-4430	HITS-CLIP	23824327
MIRT627137	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT627136	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT627135	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT638074	hsa-miR-5691	HITS-CLIP	23824327
MIRT638073	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT627134	hsa-miR-4642	HITS-CLIP	23824327
MIRT627133	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT627132	hsa-miR-5698	HITS-CLIP	23824327
MIRT627149	hsa-miR-5693	HITS-CLIP	23824327
MIRT627148	hsa-miR-6075	HITS-CLIP	23824327
MIRT627147	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627146	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627143	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT627142	hsa-miR-3135b	HITS-CLIP	23824327
MIRT627141	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT627140	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT627139	hsa-miR-3652	HITS-CLIP	23824327
MIRT627138	hsa-miR-4430	HITS-CLIP	23824327
MIRT627137	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT627134	hsa-miR-4642	HITS-CLIP	23824327
MIRT627132	hsa-miR-5698	HITS-CLIP	23824327
MIRT616149	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT616148	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT616147	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT616146	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT616145	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT616144	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT616143	hsa-miR-1976	HITS-CLIP	23824327
MIRT616142	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT616141	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT616140	hsa-miR-4290	HITS-CLIP	23824327
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT616137	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT616136	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT616135	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT616134	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT627149	hsa-miR-5693	HITS-CLIP	23824327
MIRT627148	hsa-miR-6075	HITS-CLIP	23824327
MIRT627147	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627146	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627145	hsa-miR-1267	HITS-CLIP	23824327
MIRT627144	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT627143	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT627142	hsa-miR-3135b	HITS-CLIP	23824327
MIRT627141	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT627140	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT627139	hsa-miR-3652	HITS-CLIP	23824327
MIRT627138	hsa-miR-4430	HITS-CLIP	23824327
MIRT627137	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT627136	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT627135	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT627134	hsa-miR-4642	HITS-CLIP	23824327
MIRT627133	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT627132	hsa-miR-5698	HITS-CLIP	23824327
MIRT623655	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT623654	hsa-miR-5190	HITS-CLIP	23824327
MIRT623653	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT623652	hsa-miR-4276	HITS-CLIP	23824327
MIRT623651	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616149	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT616148	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT616147	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT616146	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT616145	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT616144	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT616143	hsa-miR-1976	HITS-CLIP	23824327
MIRT616142	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT616141	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT616140	hsa-miR-4290	HITS-CLIP	23824327
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT616137	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT616136	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT616135	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT616134	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT545773	hsa-miR-548a-3p	PAR-CLIP	21572407
MIRT545772	hsa-miR-548ar-3p	PAR-CLIP	21572407
MIRT545771	hsa-miR-548az-3p	PAR-CLIP	21572407
MIRT545770	hsa-miR-548e-3p	PAR-CLIP	21572407
MIRT545769	hsa-miR-548f-3p	PAR-CLIP	21572407
MIRT545767	hsa-miR-5582-3p	PAR-CLIP	21572407
MIRT545768	hsa-miR-508-5p	PAR-CLIP	21572407
MIRT545766	hsa-miR-483-3p	PAR-CLIP	21572407
MIRT545765	hsa-miR-4724-5p	PAR-CLIP	21572407
MIRT545766	hsa-miR-483-3p	PAR-CLIP	21572407
MIRT545763	hsa-miR-4691-3p	PAR-CLIP	21572407
MIRT545764	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT545762	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT545761	hsa-miR-4539	PAR-CLIP	21572407
MIRT545760	hsa-miR-4680-5p	PAR-CLIP	21572407
MIRT545759	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT545758	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT545757	hsa-miR-6780a-3p	PAR-CLIP	21572407
MIRT448236	hsa-miR-3662	PAR-CLIP	22100165
MIRT448235	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT448234	hsa-miR-3182	PAR-CLIP	22100165
MIRT448233	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448232	hsa-miR-573	PAR-CLIP	22100165
MIRT448230	hsa-miR-6875-3p	PAR-CLIP	22100165
MIRT448231	hsa-miR-4659a-3p	PAR-CLIP	22100165
MIRT448229	hsa-miR-4659b-3p	PAR-CLIP	22100165
MIRT448236	hsa-miR-3662	PAR-CLIP	22100165
MIRT448235	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT448234	hsa-miR-3182	PAR-CLIP	22100165
MIRT448233	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448232	hsa-miR-573	PAR-CLIP	22100165
MIRT448230	hsa-miR-6875-3p	PAR-CLIP	22100165
MIRT448231	hsa-miR-4659a-3p	PAR-CLIP	22100165
MIRT448229	hsa-miR-4659b-3p	PAR-CLIP	22100165
MIRT448228	hsa-miR-548ag	PAR-CLIP	22100165
MIRT448227	hsa-miR-548ai	PAR-CLIP	22100165
MIRT448226	hsa-miR-548ba	PAR-CLIP	22100165
MIRT448225	hsa-miR-570-5p	PAR-CLIP	22100165
MIRT448224	hsa-miR-4635	PAR-CLIP	22100165
MIRT448223	hsa-miR-493-3p	PAR-CLIP	22100165
MIRT448222	hsa-miR-144-5p	PAR-CLIP	22100165
MIRT448221	hsa-miR-1251-3p	PAR-CLIP	22100165
MIRT448219	hsa-miR-6126	PAR-CLIP	22100165
MIRT448220	hsa-miR-6864-5p	PAR-CLIP	22100165
MIRT448218	hsa-miR-1273e	PAR-CLIP	22100165
MIRT448217	hsa-miR-6885-3p	PAR-CLIP	22100165
MIRT715339	hsa-miR-6801-3p	HITS-CLIP	19536157
MIRT715338	hsa-miR-6810-3p	HITS-CLIP	19536157
MIRT627148	hsa-miR-6075	HITS-CLIP	19536157
MIRT715337	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT715336	hsa-miR-4313	HITS-CLIP	19536157
MIRT686175	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686174	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686173	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686172	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686171	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686170	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686169	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686168	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686167	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686166	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686165	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686164	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686163	hsa-miR-302e	HITS-CLIP	23313552
MIRT686162	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686161	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686160	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686159	hsa-miR-520b	HITS-CLIP	23313552
MIRT686158	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686157	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686156	hsa-miR-520e	HITS-CLIP	23313552
MIRT686155	hsa-miR-4438	HITS-CLIP	23313552
MIRT702802	hsa-miR-941	HITS-CLIP	23313552
MIRT686154	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686153	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT686152	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT686151	hsa-miR-520h	HITS-CLIP	23313552
MIRT686150	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686149	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT702801	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT702800	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT686148	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686147	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686146	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT686145	hsa-miR-5095	HITS-CLIP	23313552
MIRT686144	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT686143	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT686142	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686141	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT686175	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT686174	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT686173	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT686172	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT686171	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT686170	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT686169	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT686168	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT686167	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT686166	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT686165	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT686164	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT686163	hsa-miR-302e	HITS-CLIP	23313552
MIRT686162	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT686161	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT686160	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT686159	hsa-miR-520b	HITS-CLIP	23313552
MIRT686158	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT686157	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT686156	hsa-miR-520e	HITS-CLIP	23313552
MIRT686155	hsa-miR-4438	HITS-CLIP	23313552
MIRT686154	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT686153	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT686152	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT686151	hsa-miR-520h	HITS-CLIP	23313552
MIRT686150	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT686149	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT686148	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT686147	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT686146	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT686145	hsa-miR-5095	HITS-CLIP	23313552
MIRT686144	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT686143	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT686142	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT686141	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT627149	hsa-miR-5693	HITS-CLIP	23824327
MIRT627148	hsa-miR-6075	HITS-CLIP	23824327
MIRT627147	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627146	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627145	hsa-miR-1267	HITS-CLIP	23824327
MIRT627144	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT627143	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT638075	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT627142	hsa-miR-3135b	HITS-CLIP	23824327
MIRT627141	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT627140	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT627139	hsa-miR-3652	HITS-CLIP	23824327
MIRT627138	hsa-miR-4430	HITS-CLIP	23824327
MIRT627137	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT627136	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT627135	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT638074	hsa-miR-5691	HITS-CLIP	23824327
MIRT638073	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT627134	hsa-miR-4642	HITS-CLIP	23824327
MIRT627133	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT627132	hsa-miR-5698	HITS-CLIP	23824327
MIRT627149	hsa-miR-5693	HITS-CLIP	23824327
MIRT627148	hsa-miR-6075	HITS-CLIP	23824327
MIRT627147	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627146	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627143	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT627142	hsa-miR-3135b	HITS-CLIP	23824327
MIRT627141	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT627140	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT627139	hsa-miR-3652	HITS-CLIP	23824327
MIRT627138	hsa-miR-4430	HITS-CLIP	23824327
MIRT627137	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT627134	hsa-miR-4642	HITS-CLIP	23824327
MIRT627132	hsa-miR-5698	HITS-CLIP	23824327
MIRT616149	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT616148	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT616147	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT616146	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT616145	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT616144	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT616143	hsa-miR-1976	HITS-CLIP	23824327
MIRT616142	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT616141	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT616140	hsa-miR-4290	HITS-CLIP	23824327
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT616137	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT616136	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT616135	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT616134	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT627149	hsa-miR-5693	HITS-CLIP	23824327
MIRT627148	hsa-miR-6075	HITS-CLIP	23824327
MIRT627147	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT627146	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT627145	hsa-miR-1267	HITS-CLIP	23824327
MIRT627144	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT627143	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT627142	hsa-miR-3135b	HITS-CLIP	23824327
MIRT627141	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT627140	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT627139	hsa-miR-3652	HITS-CLIP	23824327
MIRT627138	hsa-miR-4430	HITS-CLIP	23824327
MIRT627137	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT627136	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT627135	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT627134	hsa-miR-4642	HITS-CLIP	23824327
MIRT627133	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT627132	hsa-miR-5698	HITS-CLIP	23824327
MIRT623655	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT623654	hsa-miR-5190	HITS-CLIP	23824327
MIRT623653	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT623652	hsa-miR-4276	HITS-CLIP	23824327
MIRT623651	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616149	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT616148	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT616147	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT616146	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT616145	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT616144	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT616143	hsa-miR-1976	HITS-CLIP	23824327
MIRT616142	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT616141	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT616140	hsa-miR-4290	HITS-CLIP	23824327
MIRT616139	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT616138	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT616137	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT616136	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT616135	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT616134	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT545773	hsa-miR-548a-3p	PAR-CLIP	21572407
MIRT545772	hsa-miR-548ar-3p	PAR-CLIP	21572407
MIRT545771	hsa-miR-548az-3p	PAR-CLIP	21572407
MIRT545770	hsa-miR-548e-3p	PAR-CLIP	21572407
MIRT545769	hsa-miR-548f-3p	PAR-CLIP	21572407
MIRT545767	hsa-miR-5582-3p	PAR-CLIP	21572407
MIRT545768	hsa-miR-508-5p	PAR-CLIP	21572407
MIRT545766	hsa-miR-483-3p	PAR-CLIP	21572407
MIRT545765	hsa-miR-4724-5p	PAR-CLIP	21572407
MIRT545766	hsa-miR-483-3p	PAR-CLIP	21572407
MIRT545763	hsa-miR-4691-3p	PAR-CLIP	21572407
MIRT545764	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT545762	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT545761	hsa-miR-4539	PAR-CLIP	21572407
MIRT545760	hsa-miR-4680-5p	PAR-CLIP	21572407
MIRT545759	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT545758	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT545757	hsa-miR-6780a-3p	PAR-CLIP	21572407
MIRT448236	hsa-miR-3662	PAR-CLIP	22100165
MIRT448235	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT448234	hsa-miR-3182	PAR-CLIP	22100165
MIRT448233	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448232	hsa-miR-573	PAR-CLIP	22100165
MIRT448230	hsa-miR-6875-3p	PAR-CLIP	22100165
MIRT448231	hsa-miR-4659a-3p	PAR-CLIP	22100165
MIRT448229	hsa-miR-4659b-3p	PAR-CLIP	22100165
MIRT448236	hsa-miR-3662	PAR-CLIP	22100165
MIRT448235	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT448234	hsa-miR-3182	PAR-CLIP	22100165
MIRT448233	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448232	hsa-miR-573	PAR-CLIP	22100165
MIRT448230	hsa-miR-6875-3p	PAR-CLIP	22100165
MIRT448231	hsa-miR-4659a-3p	PAR-CLIP	22100165
MIRT448229	hsa-miR-4659b-3p	PAR-CLIP	22100165
MIRT448228	hsa-miR-548ag	PAR-CLIP	22100165
MIRT448227	hsa-miR-548ai	PAR-CLIP	22100165
MIRT448226	hsa-miR-548ba	PAR-CLIP	22100165
MIRT448225	hsa-miR-570-5p	PAR-CLIP	22100165
MIRT448224	hsa-miR-4635	PAR-CLIP	22100165
MIRT448223	hsa-miR-493-3p	PAR-CLIP	22100165
MIRT448222	hsa-miR-144-5p	PAR-CLIP	22100165
MIRT448221	hsa-miR-1251-3p	PAR-CLIP	22100165
MIRT448219	hsa-miR-6126	PAR-CLIP	22100165
MIRT448220	hsa-miR-6864-5p	PAR-CLIP	22100165
MIRT448218	hsa-miR-1273e	PAR-CLIP	22100165
MIRT448217	hsa-miR-6885-3p	PAR-CLIP	22100165
MIRT1054921	hsa-miR-1304	CLIP-seq
MIRT1054922	hsa-miR-185	CLIP-seq
MIRT1054923	hsa-miR-298	CLIP-seq
MIRT1054924	hsa-miR-3134	CLIP-seq
MIRT1054925	hsa-miR-3175	CLIP-seq
MIRT1054926	hsa-miR-3908	CLIP-seq
MIRT1054927	hsa-miR-4306	CLIP-seq
MIRT1054928	hsa-miR-4426	CLIP-seq
MIRT1054929	hsa-miR-4428	CLIP-seq
MIRT1054930	hsa-miR-4644	CLIP-seq
MIRT1054931	hsa-miR-4647	CLIP-seq
MIRT1054932	hsa-miR-4662b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005796	Component	Golgi lumen	IEA
GO:0005796	Component	Golgi lumen	TAS	9346953
GO:0006024	Process	Glycosaminoglycan biosynthetic process	IDA	8900198, 9988768
GO:0006024	Process	Glycosaminoglycan biosynthetic process	IEA
GO:0008146	Function	Sulfotransferase activity	IEA
GO:0008146	Function	Sulfotransferase activity	TAS	9988767
GO:0008467	Function	[heparan sulfate]-glucosamine 3-sulfotransferase activity	IBA
GO:0008467	Function	[heparan sulfate]-glucosamine 3-sulfotransferase activity	IDA	8900198, 9988768
GO:0008467	Function	[heparan sulfate]-glucosamine 3-sulfotransferase activity	IEA
GO:0008467	Function	[heparan sulfate]-glucosamine 3-sulfotransferase activity	TAS
GO:0015012	Process	Heparan sulfate proteoglycan biosynthetic process	IEA
GO:0015012	Process	Heparan sulfate proteoglycan biosynthetic process	TAS
GO:0016740	Function	Transferase activity	IEA

Other IDs

• MIM: 603244
• HGNC: 5194
• e!Ensembl: ENSG00000002587

Protein

• UniProt ID: O14792
• Protein name: Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1)
• Protein function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan (PubMed:8900198, PubMed:9346953, PubMed:9988768). Catalyzes the rate limiting step in
• PDB: 1ZRH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00685	Sulfotransfer_1	54 → 298	Sulfotransferase domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta. {ECO:0000269|PubMed:9988767}.
• Sequence:

  MAALLLGAVLLVAQPQLVPSRPAELGQQELLRKAGTLQDDVRDGVAPNGSAQQLPQTIII
  GVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTVEKT
  PAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLVR
  DGRLNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFLKLSPQ
  INASNFYFNKTKGFYCLRDSGRDRCLHESKGRAHPQVDPKLLNKLHEYFHEPNKKFFELV
  GRTFDWH

• Sequence length: 307

Pathways

KEGG:

Glycosaminoglycan biosynthesis - heparan sulfate / heparin

Reactome:

HS-GAG biosynthesis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ANKYLOSING SPONDYLITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ARTERIOSCLEROSIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Arteriosclerosis disorder	risk factor	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Coronary artery disorder	risk factor	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CROHN'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GENERALIZED ANXIETY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LATE-ONSET ALZHEIMER'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-ALCOHOLIC FATTY LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERICARDITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RESTLESS LEGS SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	33419465, 33627629	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Arteriosclerosis	Arteriosclerosis	CLINVAR_DG	15266341		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Arteriosclerosis	Arteriosclerosis	BEFREE	28126521		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Atherosclerosis	Atherosclerosis	BEFREE	28126521		★☆☆☆☆ Found in Text Mining only
Brain Diseases	Brain disease	Pubtator	33419465	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	35909476	Associate	★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	BEFREE	19812376		★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	Pubtator	19812376	Associate	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	CLINVAR_DG	15266341		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Endometriosis	Endometriosis	Pubtator	37555920	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	29104277	Associate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	35309336	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21709440, 26120938		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	22025563		★☆☆☆☆ Found in Text Mining only