IQSEC1 (IQ motif and Sec7 domain ArfGEF 1)

Gene

• Entrez ID: 9922
• Gene name: IQ motif and Sec7 domain ArfGEF 1
• Gene symbol: IQSEC1
• Synonyms (NCBI Gene): ARF-GEP100, ARFGEP100, BRAG2, GEP100, IDDSSBA
• Chromosome: 3
• Chromosome location: 3p25.2-p25.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT044004	hsa-miR-378a-5p	CLASH	23622248
MIRT040506	hsa-miR-589-3p	CLASH	23622248
MIRT038915	hsa-miR-92a-1-5p	CLASH	23622248
MIRT649174	hsa-miR-4436b-3p	HITS-CLIP	23824327
MIRT649173	hsa-miR-4632-5p	HITS-CLIP	23824327
MIRT649171	hsa-miR-6735-5p	HITS-CLIP	23824327
MIRT649172	hsa-miR-6879-5p	HITS-CLIP	23824327
MIRT649170	hsa-miR-7843-5p	HITS-CLIP	23824327
MIRT649169	hsa-miR-4650-5p	HITS-CLIP	23824327
MIRT649168	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT649167	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT649166	hsa-miR-5193	HITS-CLIP	23824327
MIRT649165	hsa-miR-1914-5p	HITS-CLIP	23824327
MIRT649164	hsa-miR-4469	HITS-CLIP	23824327
MIRT649163	hsa-miR-3655	HITS-CLIP	23824327
MIRT649162	hsa-miR-3616-3p	HITS-CLIP	23824327
MIRT649161	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT649160	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT649159	hsa-miR-6721-5p	HITS-CLIP	23824327
MIRT649158	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT649157	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT649156	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT649155	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT440431	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440430	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440431	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727430	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727429	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727428	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727427	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440430	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT649174	hsa-miR-4436b-3p	HITS-CLIP	23824327
MIRT649173	hsa-miR-4632-5p	HITS-CLIP	23824327
MIRT649171	hsa-miR-6735-5p	HITS-CLIP	23824327
MIRT649172	hsa-miR-6879-5p	HITS-CLIP	23824327
MIRT649170	hsa-miR-7843-5p	HITS-CLIP	23824327
MIRT649169	hsa-miR-4650-5p	HITS-CLIP	23824327
MIRT649168	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT649167	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT649166	hsa-miR-5193	HITS-CLIP	23824327
MIRT649165	hsa-miR-1914-5p	HITS-CLIP	23824327
MIRT649164	hsa-miR-4469	HITS-CLIP	23824327
MIRT649163	hsa-miR-3655	HITS-CLIP	23824327
MIRT649162	hsa-miR-3616-3p	HITS-CLIP	23824327
MIRT649161	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT649160	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT649159	hsa-miR-6721-5p	HITS-CLIP	23824327
MIRT649158	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT649157	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT649156	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT649155	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT1070074	hsa-miR-101	CLIP-seq
MIRT1070075	hsa-miR-103a	CLIP-seq
MIRT1070076	hsa-miR-106a	CLIP-seq
MIRT1070077	hsa-miR-106b	CLIP-seq
MIRT1070078	hsa-miR-107	CLIP-seq
MIRT1070079	hsa-miR-1179	CLIP-seq
MIRT1070080	hsa-miR-1197	CLIP-seq
MIRT1070081	hsa-miR-1227	CLIP-seq
MIRT1070082	hsa-miR-1231	CLIP-seq
MIRT1070083	hsa-miR-1234	CLIP-seq
MIRT1070084	hsa-miR-1253	CLIP-seq
MIRT1070085	hsa-miR-1270	CLIP-seq
MIRT1070086	hsa-miR-1276	CLIP-seq
MIRT1070087	hsa-miR-128	CLIP-seq
MIRT1070088	hsa-miR-1284	CLIP-seq
MIRT1070089	hsa-miR-129-5p	CLIP-seq
MIRT1070090	hsa-miR-133a	CLIP-seq
MIRT1070091	hsa-miR-133b	CLIP-seq
MIRT1070092	hsa-miR-1343	CLIP-seq
MIRT1070093	hsa-miR-143	CLIP-seq
MIRT1070094	hsa-miR-144	CLIP-seq
MIRT1070095	hsa-miR-17	CLIP-seq
MIRT1070096	hsa-miR-185	CLIP-seq
MIRT1070097	hsa-miR-18a	CLIP-seq
MIRT1070098	hsa-miR-18b	CLIP-seq
MIRT1070099	hsa-miR-1910	CLIP-seq
MIRT1070100	hsa-miR-1915	CLIP-seq
MIRT1070101	hsa-miR-197	CLIP-seq
MIRT1070102	hsa-miR-1976	CLIP-seq
MIRT1070103	hsa-miR-2052	CLIP-seq
MIRT1070104	hsa-miR-20a	CLIP-seq
MIRT1070105	hsa-miR-20b	CLIP-seq
MIRT1070106	hsa-miR-2110	CLIP-seq
MIRT1070107	hsa-miR-219-5p	CLIP-seq
MIRT1070108	hsa-miR-2681	CLIP-seq
MIRT1070109	hsa-miR-27a	CLIP-seq
MIRT1070110	hsa-miR-27b	CLIP-seq
MIRT1070111	hsa-miR-2909	CLIP-seq
MIRT1070112	hsa-miR-296-3p	CLIP-seq
MIRT1070113	hsa-miR-297	CLIP-seq
MIRT1070114	hsa-miR-3115	CLIP-seq
MIRT1070115	hsa-miR-3126-5p	CLIP-seq
MIRT1070116	hsa-miR-3147	CLIP-seq
MIRT1070117	hsa-miR-3149	CLIP-seq
MIRT1070118	hsa-miR-3150a-3p	CLIP-seq
MIRT1070119	hsa-miR-3154	CLIP-seq
MIRT1070120	hsa-miR-3166	CLIP-seq
MIRT1070121	hsa-miR-3170	CLIP-seq
MIRT1070122	hsa-miR-3175	CLIP-seq
MIRT1070123	hsa-miR-329	CLIP-seq
MIRT1070124	hsa-miR-331-5p	CLIP-seq
MIRT1070125	hsa-miR-337-3p	CLIP-seq
MIRT1070126	hsa-miR-342-3p	CLIP-seq
MIRT1070127	hsa-miR-3609	CLIP-seq
MIRT1070128	hsa-miR-3615	CLIP-seq
MIRT1070129	hsa-miR-3617	CLIP-seq
MIRT1070130	hsa-miR-362-3p	CLIP-seq
MIRT1070131	hsa-miR-3647-3p	CLIP-seq
MIRT1070132	hsa-miR-3689a-3p	CLIP-seq
MIRT1070133	hsa-miR-3689c	CLIP-seq
MIRT1070134	hsa-miR-375	CLIP-seq
MIRT1070135	hsa-miR-377	CLIP-seq
MIRT1070136	hsa-miR-384	CLIP-seq
MIRT1070137	hsa-miR-3917	CLIP-seq
MIRT1070138	hsa-miR-3942-5p	CLIP-seq
MIRT1070139	hsa-miR-4260	CLIP-seq
MIRT1070140	hsa-miR-4279	CLIP-seq
MIRT1070141	hsa-miR-4283	CLIP-seq
MIRT1070142	hsa-miR-4284	CLIP-seq
MIRT1070143	hsa-miR-4288	CLIP-seq
MIRT1070144	hsa-miR-4306	CLIP-seq
MIRT1070145	hsa-miR-4326	CLIP-seq
MIRT1070146	hsa-miR-4425	CLIP-seq
MIRT1070147	hsa-miR-4427	CLIP-seq
MIRT1070148	hsa-miR-4445	CLIP-seq
MIRT1070149	hsa-miR-4448	CLIP-seq
MIRT1070150	hsa-miR-4475	CLIP-seq
MIRT1070151	hsa-miR-4480	CLIP-seq
MIRT1070152	hsa-miR-4514	CLIP-seq
MIRT1070153	hsa-miR-4531	CLIP-seq
MIRT1070154	hsa-miR-4633-3p	CLIP-seq
MIRT1070155	hsa-miR-4641	CLIP-seq
MIRT1070156	hsa-miR-4644	CLIP-seq
MIRT1070157	hsa-miR-4645-5p	CLIP-seq
MIRT1070158	hsa-miR-4659a-3p	CLIP-seq
MIRT1070159	hsa-miR-4659b-3p	CLIP-seq
MIRT1070160	hsa-miR-4662a-5p	CLIP-seq
MIRT1070161	hsa-miR-4673	CLIP-seq
MIRT1070162	hsa-miR-4676-5p	CLIP-seq
MIRT1070163	hsa-miR-4680-3p	CLIP-seq
MIRT1070164	hsa-miR-4683	CLIP-seq
MIRT1070165	hsa-miR-4692	CLIP-seq
MIRT1070166	hsa-miR-4694-5p	CLIP-seq
MIRT1070167	hsa-miR-4700-3p	CLIP-seq
MIRT1070168	hsa-miR-4703-5p	CLIP-seq
MIRT1070169	hsa-miR-4722-3p	CLIP-seq
MIRT1070170	hsa-miR-4726-3p	CLIP-seq
MIRT1070171	hsa-miR-4727-5p	CLIP-seq
MIRT1070172	hsa-miR-4728-5p	CLIP-seq
MIRT1070173	hsa-miR-4731-3p	CLIP-seq
MIRT1070174	hsa-miR-4735-3p	CLIP-seq
MIRT1070175	hsa-miR-4749-3p	CLIP-seq
MIRT1070176	hsa-miR-4764-5p	CLIP-seq
MIRT1070177	hsa-miR-4770	CLIP-seq
MIRT1070178	hsa-miR-4781-3p	CLIP-seq
MIRT1070179	hsa-miR-4782-3p	CLIP-seq
MIRT1070180	hsa-miR-4790-3p	CLIP-seq
MIRT1070181	hsa-miR-4793-5p	CLIP-seq
MIRT1070182	hsa-miR-4796-3p	CLIP-seq
MIRT1070183	hsa-miR-4801	CLIP-seq
MIRT1070184	hsa-miR-4802-5p	CLIP-seq
MIRT1070185	hsa-miR-490-5p	CLIP-seq
MIRT1070186	hsa-miR-508-3p	CLIP-seq
MIRT1070187	hsa-miR-519d	CLIP-seq
MIRT1070188	hsa-miR-541	CLIP-seq
MIRT1070189	hsa-miR-548ag	CLIP-seq
MIRT1070190	hsa-miR-548ah	CLIP-seq
MIRT1070191	hsa-miR-548ai	CLIP-seq
MIRT1070192	hsa-miR-552	CLIP-seq
MIRT1070193	hsa-miR-575	CLIP-seq
MIRT1070194	hsa-miR-584	CLIP-seq
MIRT1070195	hsa-miR-601	CLIP-seq
MIRT1070196	hsa-miR-618	CLIP-seq
MIRT1070197	hsa-miR-620	CLIP-seq
MIRT1070198	hsa-miR-632	CLIP-seq
MIRT1070199	hsa-miR-641	CLIP-seq
MIRT1070200	hsa-miR-654-5p	CLIP-seq
MIRT1070201	hsa-miR-676	CLIP-seq
MIRT1070202	hsa-miR-93	CLIP-seq
MIRT1070203	hsa-miR-939	CLIP-seq
MIRT1070076	hsa-miR-106a	CLIP-seq
MIRT1070077	hsa-miR-106b	CLIP-seq
MIRT1070085	hsa-miR-1270	CLIP-seq
MIRT1070204	hsa-miR-1294	CLIP-seq
MIRT1070205	hsa-miR-138	CLIP-seq
MIRT1070206	hsa-miR-151-3p	CLIP-seq
MIRT1070095	hsa-miR-17	CLIP-seq
MIRT1070207	hsa-miR-190	CLIP-seq
MIRT1070208	hsa-miR-190b	CLIP-seq
MIRT1070209	hsa-miR-1914	CLIP-seq
MIRT1070104	hsa-miR-20a	CLIP-seq
MIRT1070105	hsa-miR-20b	CLIP-seq
MIRT1070210	hsa-miR-302a	CLIP-seq
MIRT1070211	hsa-miR-302b	CLIP-seq
MIRT1070212	hsa-miR-302c	CLIP-seq
MIRT1070213	hsa-miR-302d	CLIP-seq
MIRT1070214	hsa-miR-302e	CLIP-seq
MIRT1070215	hsa-miR-3150b-3p	CLIP-seq
MIRT1070216	hsa-miR-326	CLIP-seq
MIRT1070217	hsa-miR-330-5p	CLIP-seq
MIRT1070218	hsa-miR-3613-5p	CLIP-seq
MIRT1070219	hsa-miR-3678-3p	CLIP-seq
MIRT1070132	hsa-miR-3689a-3p	CLIP-seq
MIRT1070133	hsa-miR-3689c	CLIP-seq
MIRT1070220	hsa-miR-372	CLIP-seq
MIRT1070221	hsa-miR-373	CLIP-seq
MIRT1070140	hsa-miR-4279	CLIP-seq
MIRT1070222	hsa-miR-4316	CLIP-seq
MIRT1070164	hsa-miR-4683	CLIP-seq
MIRT1070223	hsa-miR-4689	CLIP-seq
MIRT1070224	hsa-miR-4695-3p	CLIP-seq
MIRT1070172	hsa-miR-4728-5p	CLIP-seq
MIRT1070225	hsa-miR-4760-3p	CLIP-seq
MIRT1070176	hsa-miR-4764-5p	CLIP-seq
MIRT1070226	hsa-miR-4779	CLIP-seq
MIRT1070227	hsa-miR-4784	CLIP-seq
MIRT1070228	hsa-miR-495	CLIP-seq
MIRT1070229	hsa-miR-516b	CLIP-seq
MIRT1070187	hsa-miR-519d	CLIP-seq
MIRT1070230	hsa-miR-520a-3p	CLIP-seq
MIRT1070231	hsa-miR-520b	CLIP-seq
MIRT1070232	hsa-miR-520c-3p	CLIP-seq
MIRT1070233	hsa-miR-520d-3p	CLIP-seq
MIRT1070234	hsa-miR-520e	CLIP-seq
MIRT1070235	hsa-miR-520f	CLIP-seq
MIRT1070236	hsa-miR-520g	CLIP-seq
MIRT1070237	hsa-miR-520h	CLIP-seq
MIRT1070238	hsa-miR-582-5p	CLIP-seq
MIRT1070197	hsa-miR-620	CLIP-seq
MIRT1070239	hsa-miR-636	CLIP-seq
MIRT1070240	hsa-miR-642a	CLIP-seq
MIRT1070241	hsa-miR-664	CLIP-seq
MIRT1070201	hsa-miR-676	CLIP-seq
MIRT1070202	hsa-miR-93	CLIP-seq
MIRT1070075	hsa-miR-103a	CLIP-seq
MIRT1070076	hsa-miR-106a	CLIP-seq
MIRT1070077	hsa-miR-106b	CLIP-seq
MIRT1070078	hsa-miR-107	CLIP-seq
MIRT1070080	hsa-miR-1197	CLIP-seq
MIRT2017206	hsa-miR-1224-5p	CLIP-seq
MIRT1070081	hsa-miR-1227	CLIP-seq
MIRT1070082	hsa-miR-1231	CLIP-seq
MIRT2017207	hsa-miR-125a-5p	CLIP-seq
MIRT2017208	hsa-miR-125b	CLIP-seq
MIRT1070085	hsa-miR-1270	CLIP-seq
MIRT2017209	hsa-miR-1271	CLIP-seq
MIRT1070087	hsa-miR-128	CLIP-seq
MIRT2017210	hsa-miR-1291	CLIP-seq
MIRT1070093	hsa-miR-143	CLIP-seq
MIRT2017211	hsa-miR-146b-3p	CLIP-seq
MIRT2017212	hsa-miR-147	CLIP-seq
MIRT1070095	hsa-miR-17	CLIP-seq
MIRT1070099	hsa-miR-1910	CLIP-seq
MIRT1070102	hsa-miR-1976	CLIP-seq
MIRT1070103	hsa-miR-2052	CLIP-seq
MIRT1070104	hsa-miR-20a	CLIP-seq
MIRT1070105	hsa-miR-20b	CLIP-seq
MIRT2017213	hsa-miR-2115	CLIP-seq
MIRT2017214	hsa-miR-221	CLIP-seq
MIRT2017215	hsa-miR-222	CLIP-seq
MIRT2017216	hsa-miR-2277-3p	CLIP-seq
MIRT2017217	hsa-miR-2392	CLIP-seq
MIRT1070113	hsa-miR-297	CLIP-seq
MIRT2017218	hsa-miR-3064-3p	CLIP-seq
MIRT2017219	hsa-miR-3074-3p	CLIP-seq
MIRT1070114	hsa-miR-3115	CLIP-seq
MIRT1070115	hsa-miR-3126-5p	CLIP-seq
MIRT2017220	hsa-miR-3131	CLIP-seq
MIRT1070117	hsa-miR-3149	CLIP-seq
MIRT1070215	hsa-miR-3150b-3p	CLIP-seq
MIRT1070121	hsa-miR-3170	CLIP-seq
MIRT2017221	hsa-miR-3173-5p	CLIP-seq
MIRT1070123	hsa-miR-329	CLIP-seq
MIRT1070125	hsa-miR-337-3p	CLIP-seq
MIRT1070126	hsa-miR-342-3p	CLIP-seq
MIRT1070127	hsa-miR-3609	CLIP-seq
MIRT1070128	hsa-miR-3615	CLIP-seq
MIRT1070129	hsa-miR-3617	CLIP-seq
MIRT2017222	hsa-miR-3620	CLIP-seq
MIRT1070130	hsa-miR-362-3p	CLIP-seq
MIRT2017223	hsa-miR-3659	CLIP-seq
MIRT2017224	hsa-miR-3660	CLIP-seq
MIRT2017225	hsa-miR-3686	CLIP-seq
MIRT2017226	hsa-miR-369-3p	CLIP-seq
MIRT2017227	hsa-miR-370	CLIP-seq
MIRT2017228	hsa-miR-371b-5p	CLIP-seq
MIRT2017229	hsa-miR-374a	CLIP-seq
MIRT2017230	hsa-miR-374b	CLIP-seq
MIRT1070134	hsa-miR-375	CLIP-seq
MIRT1070135	hsa-miR-377	CLIP-seq
MIRT2017231	hsa-miR-380	CLIP-seq
MIRT1070137	hsa-miR-3917	CLIP-seq
MIRT2017232	hsa-miR-4252	CLIP-seq
MIRT1070139	hsa-miR-4260	CLIP-seq
MIRT2017233	hsa-miR-4268	CLIP-seq
MIRT1070143	hsa-miR-4288	CLIP-seq
MIRT2017234	hsa-miR-4302	CLIP-seq
MIRT2017235	hsa-miR-4310	CLIP-seq
MIRT2017236	hsa-miR-4312	CLIP-seq
MIRT2017237	hsa-miR-4319	CLIP-seq
MIRT2017238	hsa-miR-4418	CLIP-seq
MIRT2017239	hsa-miR-4419a	CLIP-seq
MIRT2017240	hsa-miR-4421	CLIP-seq
MIRT1070147	hsa-miR-4427	CLIP-seq
MIRT2017241	hsa-miR-4436a	CLIP-seq
MIRT2017242	hsa-miR-4438	CLIP-seq
MIRT2017243	hsa-miR-4447	CLIP-seq
MIRT1070149	hsa-miR-4448	CLIP-seq
MIRT2017244	hsa-miR-4472	CLIP-seq
MIRT2017245	hsa-miR-4510	CLIP-seq
MIRT2017246	hsa-miR-4522	CLIP-seq
MIRT2017247	hsa-miR-4526	CLIP-seq
MIRT2017248	hsa-miR-4528	CLIP-seq
MIRT1070153	hsa-miR-4531	CLIP-seq
MIRT2017249	hsa-miR-4658	CLIP-seq
MIRT1070158	hsa-miR-4659a-3p	CLIP-seq
MIRT1070159	hsa-miR-4659b-3p	CLIP-seq
MIRT1070160	hsa-miR-4662a-5p	CLIP-seq
MIRT1070162	hsa-miR-4676-5p	CLIP-seq
MIRT1070163	hsa-miR-4680-3p	CLIP-seq
MIRT1070164	hsa-miR-4683	CLIP-seq
MIRT2017250	hsa-miR-4684-3p	CLIP-seq
MIRT2017251	hsa-miR-4690-3p	CLIP-seq
MIRT2017252	hsa-miR-4708-5p	CLIP-seq
MIRT2017253	hsa-miR-4710	CLIP-seq
MIRT2017254	hsa-miR-4714-5p	CLIP-seq
MIRT2017255	hsa-miR-4717-3p	CLIP-seq
MIRT1070171	hsa-miR-4727-5p	CLIP-seq
MIRT2017256	hsa-miR-4732-3p	CLIP-seq
MIRT2017257	hsa-miR-4742-3p	CLIP-seq
MIRT1070175	hsa-miR-4749-3p	CLIP-seq
MIRT2017258	hsa-miR-4751	CLIP-seq
MIRT1070177	hsa-miR-4770	CLIP-seq
MIRT2017259	hsa-miR-4778-5p	CLIP-seq
MIRT1070227	hsa-miR-4784	CLIP-seq
MIRT1070182	hsa-miR-4796-3p	CLIP-seq
MIRT2017260	hsa-miR-4802-3p	CLIP-seq
MIRT2017261	hsa-miR-509-3-5p	CLIP-seq
MIRT2017262	hsa-miR-509-5p	CLIP-seq
MIRT1070229	hsa-miR-516b	CLIP-seq
MIRT1070187	hsa-miR-519d	CLIP-seq
MIRT2017263	hsa-miR-545	CLIP-seq
MIRT1070189	hsa-miR-548ag	CLIP-seq
MIRT1070190	hsa-miR-548ah	CLIP-seq
MIRT1070191	hsa-miR-548ai	CLIP-seq
MIRT2017264	hsa-miR-567	CLIP-seq
MIRT2017265	hsa-miR-574-5p	CLIP-seq
MIRT1070193	hsa-miR-575	CLIP-seq
MIRT2017266	hsa-miR-576-3p	CLIP-seq
MIRT2017267	hsa-miR-611	CLIP-seq
MIRT1070197	hsa-miR-620	CLIP-seq
MIRT2017268	hsa-miR-621	CLIP-seq
MIRT1070198	hsa-miR-632	CLIP-seq
MIRT1070199	hsa-miR-641	CLIP-seq
MIRT1070240	hsa-miR-642a	CLIP-seq
MIRT2017269	hsa-miR-665	CLIP-seq
MIRT2017270	hsa-miR-670	CLIP-seq
MIRT2017271	hsa-miR-767-3p	CLIP-seq
MIRT2017272	hsa-miR-874	CLIP-seq
MIRT2017273	hsa-miR-885-3p	CLIP-seq
MIRT2017274	hsa-miR-890	CLIP-seq
MIRT1070202	hsa-miR-93	CLIP-seq
MIRT2017275	hsa-miR-96	CLIP-seq
MIRT1070075	hsa-miR-103a	CLIP-seq
MIRT1070078	hsa-miR-107	CLIP-seq
MIRT1070080	hsa-miR-1197	CLIP-seq
MIRT1070081	hsa-miR-1227	CLIP-seq
MIRT2249164	hsa-miR-1265	CLIP-seq
MIRT2249165	hsa-miR-1286	CLIP-seq
MIRT2249166	hsa-miR-1299	CLIP-seq
MIRT1070205	hsa-miR-138	CLIP-seq
MIRT1070096	hsa-miR-185	CLIP-seq
MIRT2017213	hsa-miR-2115	CLIP-seq
MIRT2017217	hsa-miR-2392	CLIP-seq
MIRT2017218	hsa-miR-3064-3p	CLIP-seq
MIRT1070120	hsa-miR-3166	CLIP-seq
MIRT1070123	hsa-miR-329	CLIP-seq
MIRT1070129	hsa-miR-3617	CLIP-seq
MIRT1070130	hsa-miR-362-3p	CLIP-seq
MIRT2017228	hsa-miR-371b-5p	CLIP-seq
MIRT2017231	hsa-miR-380	CLIP-seq
MIRT1070144	hsa-miR-4306	CLIP-seq
MIRT2249167	hsa-miR-4327	CLIP-seq
MIRT2017239	hsa-miR-4419a	CLIP-seq
MIRT2249168	hsa-miR-4495	CLIP-seq
MIRT2249169	hsa-miR-4503	CLIP-seq
MIRT2017245	hsa-miR-4510	CLIP-seq
MIRT2249170	hsa-miR-451b	CLIP-seq
MIRT2249171	hsa-miR-4534	CLIP-seq
MIRT1070154	hsa-miR-4633-3p	CLIP-seq
MIRT1070156	hsa-miR-4644	CLIP-seq
MIRT1070224	hsa-miR-4695-3p	CLIP-seq
MIRT2249172	hsa-miR-4698	CLIP-seq
MIRT2249173	hsa-miR-4722-5p	CLIP-seq
MIRT2249174	hsa-miR-508-5p	CLIP-seq
MIRT2017266	hsa-miR-576-3p	CLIP-seq
MIRT1070199	hsa-miR-641	CLIP-seq
MIRT2249175	hsa-miR-651	CLIP-seq
MIRT2249176	hsa-miR-766	CLIP-seq
MIRT2249177	hsa-miR-875-3p	CLIP-seq
MIRT1070205	hsa-miR-138	CLIP-seq
MIRT2552730	hsa-miR-4766-5p	CLIP-seq
MIRT2682902	hsa-miR-3682-5p	CLIP-seq
MIRT2017231	hsa-miR-380	CLIP-seq
MIRT2682903	hsa-miR-4315	CLIP-seq
MIRT2249168	hsa-miR-4495	CLIP-seq
MIRT2682904	hsa-miR-4790-5p	CLIP-seq
MIRT2682905	hsa-miR-888	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005515	Function	Protein binding	IPI	27265506, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0008021	Component	Synaptic vesicle	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0014069	Component	Postsynaptic density	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0032012	Process	Regulation of ARF protein signal transduction	IEA
GO:0045202	Component	Synapse	IEA
GO:0051549	Process	Positive regulation of keratinocyte migration	ISS
GO:0060996	Process	Dendritic spine development	ISS
GO:0120183	Process	Positive regulation of focal adhesion disassembly	ISS

Other IDs

• MIM: 610166
• HGNC: 29112
• e!Ensembl: ENSG00000144711

Protein

• UniProt ID: Q6DN90
• Protein name: IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2)
• Protein function: Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:11226253, PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nu
• PDB: 3QWM, 4C0A, 5NLV, 5NLY, 6FNE, 7VMB
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01369	Sec7	524 → 712	Sec7 domain	Domain
  PF16453	IQ_SEC7_PH	743 → 879	PH domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis. {ECO:0000269|PubMed:11226253, ECO:0000269|Pub
• Sequence:

  MWCLHCNSERTQSLLELELDSGVEGEAPSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEH
  TSVGAYGLYSGPPGQQQRTRRPKLQHSTSILRKQAEEEAIKRSRSLSESYELSSDLQDKQ
  VEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFS
  FEGPEKVHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTTLKSPAPSSDFADAITELE
  DAFSRQVKSLAESIDDALNCRSLHTEEAPALDAARARDTEPQTALHGMDHRKLDEMTASY
  SDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCR
  STPSLERQEQRLRVEHLPLLTIEPPSDSSVDLSDRSERGSLKRQSAYERSLGGQQGSPKH
  GPHSGAPKSLPREEPELRPRPPRPLDSHLAINGSANRQSKSESDYSDGDNDSINSTSNSN
  DTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSNDVIRKRHYRIGLNLFNKKPE
  KGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFS
  TMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAII
  LLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVS
  QVQKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFL
  FNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLI
  NFNAPNPQDRKKFTDDLRESIAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNG
  TLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFEPLQPSV
  LCS

• Sequence length: 963

Pathways

KEGG:

Endocytosis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Intellectual developmental disorder with short stature and behavioral abnormalities	Pathogenic; Likely pathogenic	rs765723607, rs758170522	RCV000860023 RCV000860024	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AUTOSOMAL RECESSIVE NON-SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet, Orphanet Disgenet, Orphanet Disgenet, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONOTRUNCAL HEART MALFORMATIONS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEVELOPMENTAL DISABILITIES	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Developmental disorder	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IQSEC1-related disorder	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodevelopmental abnormality	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERIPHERAL ARTERIAL DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPONDYLOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	21966491		★☆☆☆☆ Found in Text Mining only
Atrophy	Atrophy	Pubtator	33319642	Associate	★☆☆☆☆ Found in Text Mining only
Autosomal recessive non-syndromic intellectual disability	Non-Syndromic Intellectual Disability	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Carcinoma	Breast Carcinoma	BEFREE	18084281, 23747719		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	23747719, 24116160	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	22701712	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	22491060	Associate	★☆☆☆☆ Found in Text Mining only
Ductal Carcinoma	Ductal Carcinoma	BEFREE	18084281		★☆☆☆☆ Found in Text Mining only
Dwarfism	Dwarfism	BEFREE	31607425		★☆☆☆☆ Found in Text Mining only
Dwarfism	Dwarfism	GENOMICS_ENGLAND_DG	31607425		★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	Pubtator	37246165	Associate	★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	GENOMICS_ENGLAND_DG	31607425		★☆☆☆☆ Found in Text Mining only
Glomerulonephritis IGA	Iga nephropathy	Pubtator	33319642	Associate	★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	27880014		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	31607425		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	GENOMICS_ENGLAND_DG	31607425		★☆☆☆☆ Found in Text Mining only
Intracranial Aneurysm	Intracranial Aneurysm	BEFREE	20613766		★☆☆☆☆ Found in Text Mining only
Intracranial Aneurysm	Intracranial Aneurysm	GWASDB_DG	20613766		★☆☆☆☆ Found in Text Mining only
Kidney Neoplasms	Kidney neoplasm	Pubtator	24516231	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	22701712		★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	22701712		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	CTD_human_DG	27935865		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	21966491	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Head and Neck Neoplasm	Head and neck cancer	BEFREE	27880014		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	18084281, 23747719		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	CTD_human_DG	27935865		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	22662237, 29851753		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	18084281, 19416474, 21858086, 28923919		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	18084281		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29329590		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	23202957	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	22662237, 29851753		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pancreatic carcinoma	Pancreatic carcinoma	GWASCAT_DG	28470677		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Periodontitis	Periodontitis	Pubtator	35179257	Associate	★☆☆☆☆ Found in Text Mining only