Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	9915
Gene name	Aryl hydrocarbon receptor nuclear translocator 2
Gene symbol	ARNT2
Synonyms (NCBI Gene)	WEDASbHLHe1
Chromosome	15
Chromosome location	15q25.1
Summary	This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1595993043	G>A	Likely-pathogenic	Intron variant
rs1596021185	->TC	Pathogenic	Coding sequence variant, frameshift variant

380

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miRTarBase ID	miRNA	Experiments	Reference
MIRT029615	hsa-miR-26b-5p	Microarray	19088304
MIRT051426	hsa-let-7e-5p	CLASH	23622248
MIRT799440	hsa-miR-1197	CLIP-seq
MIRT799441	hsa-miR-1207-5p	CLIP-seq
MIRT799442	hsa-miR-124	CLIP-seq
MIRT799443	hsa-miR-1257	CLIP-seq
MIRT799444	hsa-miR-1265	CLIP-seq
MIRT799445	hsa-miR-1275	CLIP-seq
MIRT799446	hsa-miR-1287	CLIP-seq
MIRT799447	hsa-miR-1291	CLIP-seq
MIRT799448	hsa-miR-1295	CLIP-seq
MIRT799449	hsa-miR-129-5p	CLIP-seq
MIRT799450	hsa-miR-1827	CLIP-seq
MIRT799451	hsa-miR-2467-3p	CLIP-seq
MIRT799452	hsa-miR-299-3p	CLIP-seq
MIRT799453	hsa-miR-3117-3p	CLIP-seq
MIRT799454	hsa-miR-3120-3p	CLIP-seq
MIRT799455	hsa-miR-3123	CLIP-seq
MIRT799456	hsa-miR-3135b	CLIP-seq
MIRT799457	hsa-miR-3174	CLIP-seq
MIRT799458	hsa-miR-3185	CLIP-seq
MIRT799459	hsa-miR-3189-5p	CLIP-seq
MIRT799460	hsa-miR-3192	CLIP-seq
MIRT799461	hsa-miR-323-3p	CLIP-seq
MIRT799462	hsa-miR-328	CLIP-seq
MIRT799463	hsa-miR-335	CLIP-seq
MIRT799464	hsa-miR-345	CLIP-seq
MIRT799465	hsa-miR-3605-5p	CLIP-seq
MIRT799466	hsa-miR-3612	CLIP-seq
MIRT799467	hsa-miR-3689a-3p	CLIP-seq
MIRT799468	hsa-miR-3689c	CLIP-seq
MIRT799469	hsa-miR-370	CLIP-seq
MIRT799470	hsa-miR-376a	CLIP-seq
MIRT799471	hsa-miR-376b	CLIP-seq
MIRT799472	hsa-miR-382	CLIP-seq
MIRT799473	hsa-miR-384	CLIP-seq
MIRT799474	hsa-miR-3919	CLIP-seq
MIRT799475	hsa-miR-3925-3p	CLIP-seq
MIRT799476	hsa-miR-3925-5p	CLIP-seq
MIRT799477	hsa-miR-3941	CLIP-seq
MIRT799478	hsa-miR-3944-3p	CLIP-seq
MIRT799479	hsa-miR-3976	CLIP-seq
MIRT799480	hsa-miR-4256	CLIP-seq
MIRT799481	hsa-miR-4257	CLIP-seq
MIRT799482	hsa-miR-4260	CLIP-seq
MIRT799483	hsa-miR-4283	CLIP-seq
MIRT799484	hsa-miR-4284	CLIP-seq
MIRT799485	hsa-miR-4292	CLIP-seq
MIRT799486	hsa-miR-4301	CLIP-seq
MIRT799487	hsa-miR-4327	CLIP-seq
MIRT799488	hsa-miR-4436b-3p	CLIP-seq
MIRT799489	hsa-miR-4443	CLIP-seq
MIRT799490	hsa-miR-4446-3p	CLIP-seq
MIRT799491	hsa-miR-4457	CLIP-seq
MIRT799492	hsa-miR-4477b	CLIP-seq
MIRT799493	hsa-miR-4489	CLIP-seq
MIRT799494	hsa-miR-4491	CLIP-seq
MIRT799495	hsa-miR-4492	CLIP-seq
MIRT799496	hsa-miR-4498	CLIP-seq
MIRT799497	hsa-miR-4514	CLIP-seq
MIRT799498	hsa-miR-4643	CLIP-seq
MIRT799499	hsa-miR-4656	CLIP-seq
MIRT799500	hsa-miR-4657	CLIP-seq
MIRT799501	hsa-miR-466	CLIP-seq
MIRT799502	hsa-miR-4664-3p	CLIP-seq
MIRT799503	hsa-miR-4665-5p	CLIP-seq
MIRT799504	hsa-miR-4667-5p	CLIP-seq
MIRT799505	hsa-miR-4672	CLIP-seq
MIRT799506	hsa-miR-4675	CLIP-seq
MIRT799507	hsa-miR-4691-5p	CLIP-seq
MIRT799508	hsa-miR-4692	CLIP-seq
MIRT799509	hsa-miR-4700-5p	CLIP-seq
MIRT799510	hsa-miR-4717-5p	CLIP-seq
MIRT799511	hsa-miR-4721	CLIP-seq
MIRT799512	hsa-miR-4728-5p	CLIP-seq
MIRT799513	hsa-miR-4731-3p	CLIP-seq
MIRT799514	hsa-miR-4741	CLIP-seq
MIRT799515	hsa-miR-4758-3p	CLIP-seq
MIRT799516	hsa-miR-4763-3p	CLIP-seq
MIRT799517	hsa-miR-4764-5p	CLIP-seq
MIRT799518	hsa-miR-4778-3p	CLIP-seq
MIRT799519	hsa-miR-4778-5p	CLIP-seq
MIRT799520	hsa-miR-4789-3p	CLIP-seq
MIRT799521	hsa-miR-4789-5p	CLIP-seq
MIRT799522	hsa-miR-4796-5p	CLIP-seq
MIRT799523	hsa-miR-4797-5p	CLIP-seq
MIRT799524	hsa-miR-4801	CLIP-seq
MIRT799525	hsa-miR-506	CLIP-seq
MIRT799526	hsa-miR-508-5p	CLIP-seq
MIRT799527	hsa-miR-513b	CLIP-seq
MIRT799528	hsa-miR-550a	CLIP-seq
MIRT799529	hsa-miR-596	CLIP-seq
MIRT799530	hsa-miR-625	CLIP-seq
MIRT799531	hsa-miR-637	CLIP-seq
MIRT799532	hsa-miR-645	CLIP-seq
MIRT799533	hsa-miR-650	CLIP-seq
MIRT799534	hsa-miR-711	CLIP-seq
MIRT799535	hsa-miR-762	CLIP-seq
MIRT799536	hsa-miR-885-5p	CLIP-seq
MIRT799537	hsa-miR-892b	CLIP-seq
MIRT799538	hsa-miR-944	CLIP-seq
MIRT1936047	hsa-miR-106a	CLIP-seq
MIRT1936048	hsa-miR-106b	CLIP-seq
MIRT799440	hsa-miR-1197	CLIP-seq
MIRT1936049	hsa-miR-1200	CLIP-seq
MIRT1936050	hsa-miR-1205	CLIP-seq
MIRT799441	hsa-miR-1207-5p	CLIP-seq
MIRT799442	hsa-miR-124	CLIP-seq
MIRT1936051	hsa-miR-1252	CLIP-seq
MIRT1936052	hsa-miR-1254	CLIP-seq
MIRT1936053	hsa-miR-128	CLIP-seq
MIRT1936054	hsa-miR-1285	CLIP-seq
MIRT1936055	hsa-miR-1298	CLIP-seq
MIRT1936056	hsa-miR-1321	CLIP-seq
MIRT1936057	hsa-miR-1324	CLIP-seq
MIRT1936058	hsa-miR-138	CLIP-seq
MIRT1936059	hsa-miR-144	CLIP-seq
MIRT1936060	hsa-miR-1587	CLIP-seq
MIRT1936061	hsa-miR-17	CLIP-seq
MIRT1936062	hsa-miR-181a	CLIP-seq
MIRT1936063	hsa-miR-181b	CLIP-seq
MIRT1936064	hsa-miR-181c	CLIP-seq
MIRT1936065	hsa-miR-181d	CLIP-seq
MIRT1936066	hsa-miR-1909	CLIP-seq
MIRT1936067	hsa-miR-192	CLIP-seq
MIRT1936068	hsa-miR-20a	CLIP-seq
MIRT1936069	hsa-miR-20b	CLIP-seq
MIRT1936070	hsa-miR-2113	CLIP-seq
MIRT1936071	hsa-miR-215	CLIP-seq
MIRT1936072	hsa-miR-23a	CLIP-seq
MIRT1936073	hsa-miR-23b	CLIP-seq
MIRT1936074	hsa-miR-23c	CLIP-seq
MIRT1936075	hsa-miR-24	CLIP-seq
MIRT1936076	hsa-miR-27a	CLIP-seq
MIRT1936077	hsa-miR-27b	CLIP-seq
MIRT1936078	hsa-miR-2861	CLIP-seq
MIRT1936079	hsa-miR-296-5p	CLIP-seq
MIRT1936080	hsa-miR-298	CLIP-seq
MIRT799452	hsa-miR-299-3p	CLIP-seq
MIRT1936081	hsa-miR-302a	CLIP-seq
MIRT1936082	hsa-miR-302b	CLIP-seq
MIRT1936083	hsa-miR-302c	CLIP-seq
MIRT1936084	hsa-miR-302d	CLIP-seq
MIRT1936085	hsa-miR-302e	CLIP-seq
MIRT1936086	hsa-miR-3116	CLIP-seq
MIRT799453	hsa-miR-3117-3p	CLIP-seq
MIRT799454	hsa-miR-3120-3p	CLIP-seq
MIRT1936087	hsa-miR-3120-5p	CLIP-seq
MIRT799455	hsa-miR-3123	CLIP-seq
MIRT1936088	hsa-miR-3126-5p	CLIP-seq
MIRT1936089	hsa-miR-3150a-3p	CLIP-seq
MIRT1936090	hsa-miR-3158-5p	CLIP-seq
MIRT1936091	hsa-miR-3161	CLIP-seq
MIRT1936092	hsa-miR-3163	CLIP-seq
MIRT1936093	hsa-miR-3175	CLIP-seq
MIRT1936094	hsa-miR-3177-3p	CLIP-seq
MIRT1936095	hsa-miR-3187-5p	CLIP-seq
MIRT799460	hsa-miR-3192	CLIP-seq
MIRT1936096	hsa-miR-326	CLIP-seq
MIRT1936097	hsa-miR-330-5p	CLIP-seq
MIRT1936098	hsa-miR-331-3p	CLIP-seq
MIRT799463	hsa-miR-335	CLIP-seq
MIRT1936099	hsa-miR-346	CLIP-seq
MIRT1936100	hsa-miR-3609	CLIP-seq
MIRT1936101	hsa-miR-3648	CLIP-seq
MIRT1936102	hsa-miR-3657	CLIP-seq
MIRT1936103	hsa-miR-3663-3p	CLIP-seq
MIRT1936104	hsa-miR-3677-5p	CLIP-seq
MIRT799467	hsa-miR-3689a-3p	CLIP-seq
MIRT799468	hsa-miR-3689c	CLIP-seq
MIRT799469	hsa-miR-370	CLIP-seq
MIRT1936105	hsa-miR-372	CLIP-seq
MIRT1936106	hsa-miR-373	CLIP-seq
MIRT799470	hsa-miR-376a	CLIP-seq
MIRT799471	hsa-miR-376b	CLIP-seq
MIRT1936107	hsa-miR-378g	CLIP-seq
MIRT1936108	hsa-miR-3907	CLIP-seq
MIRT1936109	hsa-miR-3913-3p	CLIP-seq
MIRT1936110	hsa-miR-3918	CLIP-seq
MIRT799475	hsa-miR-3925-3p	CLIP-seq
MIRT799476	hsa-miR-3925-5p	CLIP-seq
MIRT799477	hsa-miR-3941	CLIP-seq
MIRT799479	hsa-miR-3976	CLIP-seq
MIRT1936111	hsa-miR-4252	CLIP-seq
MIRT1936112	hsa-miR-4253	CLIP-seq
MIRT1936113	hsa-miR-4262	CLIP-seq
MIRT1936114	hsa-miR-4270	CLIP-seq
MIRT1936115	hsa-miR-4276	CLIP-seq
MIRT799484	hsa-miR-4284	CLIP-seq
MIRT1936116	hsa-miR-4286	CLIP-seq
MIRT1936117	hsa-miR-4288	CLIP-seq
MIRT799485	hsa-miR-4292	CLIP-seq
MIRT1936118	hsa-miR-4299	CLIP-seq
MIRT1936119	hsa-miR-4300	CLIP-seq
MIRT799486	hsa-miR-4301	CLIP-seq
MIRT1936120	hsa-miR-4308	CLIP-seq
MIRT1936121	hsa-miR-4314	CLIP-seq
MIRT1936122	hsa-miR-4318	CLIP-seq
MIRT1936123	hsa-miR-4324	CLIP-seq
MIRT799487	hsa-miR-4327	CLIP-seq
MIRT1936124	hsa-miR-4417	CLIP-seq
MIRT1936125	hsa-miR-4434	CLIP-seq
MIRT1936126	hsa-miR-4441	CLIP-seq
MIRT1936127	hsa-miR-4445	CLIP-seq
MIRT799490	hsa-miR-4446-3p	CLIP-seq
MIRT1936128	hsa-miR-4446-5p	CLIP-seq
MIRT799491	hsa-miR-4457	CLIP-seq
MIRT1936129	hsa-miR-4474-3p	CLIP-seq
MIRT1936130	hsa-miR-4476	CLIP-seq
MIRT799492	hsa-miR-4477b	CLIP-seq
MIRT1936131	hsa-miR-4481	CLIP-seq
MIRT1936132	hsa-miR-4486	CLIP-seq
MIRT799494	hsa-miR-4491	CLIP-seq
MIRT799495	hsa-miR-4492	CLIP-seq
MIRT1936133	hsa-miR-4496	CLIP-seq
MIRT799496	hsa-miR-4498	CLIP-seq
MIRT1936134	hsa-miR-4505	CLIP-seq
MIRT1936135	hsa-miR-450b-3p	CLIP-seq
MIRT1936136	hsa-miR-4516	CLIP-seq
MIRT1936137	hsa-miR-4521	CLIP-seq
MIRT1936138	hsa-miR-4522	CLIP-seq
MIRT1936139	hsa-miR-4533	CLIP-seq
MIRT1936140	hsa-miR-4639-3p	CLIP-seq
MIRT1936141	hsa-miR-4641	CLIP-seq
MIRT799498	hsa-miR-4643	CLIP-seq
MIRT1936142	hsa-miR-4646-5p	CLIP-seq
MIRT1936143	hsa-miR-4648	CLIP-seq
MIRT1936144	hsa-miR-4649-5p	CLIP-seq
MIRT1936145	hsa-miR-4650-5p	CLIP-seq
MIRT1936146	hsa-miR-4654	CLIP-seq
MIRT799499	hsa-miR-4656	CLIP-seq
MIRT799500	hsa-miR-4657	CLIP-seq
MIRT799501	hsa-miR-466	CLIP-seq
MIRT1936147	hsa-miR-4669	CLIP-seq
MIRT799505	hsa-miR-4672	CLIP-seq
MIRT799506	hsa-miR-4675	CLIP-seq
MIRT1936148	hsa-miR-4676-5p	CLIP-seq
MIRT1936149	hsa-miR-4685-5p	CLIP-seq
MIRT1936150	hsa-miR-4697-3p	CLIP-seq
MIRT1936151	hsa-miR-4705	CLIP-seq
MIRT1936152	hsa-miR-4713-3p	CLIP-seq
MIRT1936153	hsa-miR-4716-5p	CLIP-seq
MIRT1936154	hsa-miR-4719	CLIP-seq
MIRT1936155	hsa-miR-4723-5p	CLIP-seq
MIRT1936156	hsa-miR-4727-5p	CLIP-seq
MIRT799512	hsa-miR-4728-5p	CLIP-seq
MIRT799513	hsa-miR-4731-3p	CLIP-seq
MIRT1936157	hsa-miR-4738-3p	CLIP-seq
MIRT1936158	hsa-miR-4739	CLIP-seq
MIRT799514	hsa-miR-4741	CLIP-seq
MIRT1936159	hsa-miR-4745-5p	CLIP-seq
MIRT1936160	hsa-miR-4755-3p	CLIP-seq
MIRT1936161	hsa-miR-4756-5p	CLIP-seq
MIRT1936162	hsa-miR-4761-5p	CLIP-seq
MIRT799516	hsa-miR-4763-3p	CLIP-seq
MIRT1936163	hsa-miR-4769-3p	CLIP-seq
MIRT1936164	hsa-miR-4769-5p	CLIP-seq
MIRT1936165	hsa-miR-4772-5p	CLIP-seq
MIRT1936166	hsa-miR-4777-5p	CLIP-seq
MIRT1936167	hsa-miR-4786-5p	CLIP-seq
MIRT799520	hsa-miR-4789-3p	CLIP-seq
MIRT799521	hsa-miR-4789-5p	CLIP-seq
MIRT1936168	hsa-miR-4796-3p	CLIP-seq
MIRT799522	hsa-miR-4796-5p	CLIP-seq
MIRT799523	hsa-miR-4797-5p	CLIP-seq
MIRT799524	hsa-miR-4801	CLIP-seq
MIRT1936169	hsa-miR-486-3p	CLIP-seq
MIRT1936170	hsa-miR-491-5p	CLIP-seq
MIRT1936171	hsa-miR-499-3p	CLIP-seq
MIRT1936172	hsa-miR-499a-3p	CLIP-seq
MIRT1936173	hsa-miR-502-5p	CLIP-seq
MIRT799525	hsa-miR-506	CLIP-seq
MIRT1936174	hsa-miR-512-3p	CLIP-seq
MIRT799527	hsa-miR-513b	CLIP-seq
MIRT1936175	hsa-miR-518d-5p	CLIP-seq
MIRT1936176	hsa-miR-519b-5p	CLIP-seq
MIRT1936177	hsa-miR-519c-5p	CLIP-seq
MIRT1936178	hsa-miR-519d	CLIP-seq
MIRT1936179	hsa-miR-520a-3p	CLIP-seq
MIRT1936180	hsa-miR-520b	CLIP-seq
MIRT1936181	hsa-miR-520c-3p	CLIP-seq
MIRT1936182	hsa-miR-520c-5p	CLIP-seq
MIRT1936183	hsa-miR-520d-3p	CLIP-seq
MIRT1936184	hsa-miR-520e	CLIP-seq
MIRT1936185	hsa-miR-526a	CLIP-seq
MIRT1936186	hsa-miR-541	CLIP-seq
MIRT1936187	hsa-miR-543	CLIP-seq
MIRT1936188	hsa-miR-544b	CLIP-seq
MIRT1936189	hsa-miR-548ah	CLIP-seq
MIRT1936190	hsa-miR-548q	CLIP-seq
MIRT799528	hsa-miR-550a	CLIP-seq
MIRT1936191	hsa-miR-575	CLIP-seq
MIRT1936192	hsa-miR-577	CLIP-seq
MIRT1936193	hsa-miR-585	CLIP-seq
MIRT1936194	hsa-miR-604	CLIP-seq
MIRT1936195	hsa-miR-612	CLIP-seq
MIRT1936196	hsa-miR-626	CLIP-seq
MIRT1936197	hsa-miR-632	CLIP-seq
MIRT1936198	hsa-miR-638	CLIP-seq
MIRT799532	hsa-miR-645	CLIP-seq
MIRT1936199	hsa-miR-647	CLIP-seq
MIRT1936200	hsa-miR-654-3p	CLIP-seq
MIRT1936201	hsa-miR-654-5p	CLIP-seq
MIRT1936202	hsa-miR-661	CLIP-seq
MIRT1936203	hsa-miR-668	CLIP-seq
MIRT1936204	hsa-miR-670	CLIP-seq
MIRT1936205	hsa-miR-7	CLIP-seq
MIRT799534	hsa-miR-711	CLIP-seq
MIRT799535	hsa-miR-762	CLIP-seq
MIRT1936206	hsa-miR-769-3p	CLIP-seq
MIRT1936207	hsa-miR-873	CLIP-seq
MIRT799536	hsa-miR-885-5p	CLIP-seq
MIRT799537	hsa-miR-892b	CLIP-seq
MIRT1936208	hsa-miR-920	CLIP-seq
MIRT1936209	hsa-miR-93	CLIP-seq
MIRT1936210	hsa-miR-939	CLIP-seq
MIRT799441	hsa-miR-1207-5p	CLIP-seq
MIRT799442	hsa-miR-124	CLIP-seq
MIRT1936053	hsa-miR-128	CLIP-seq
MIRT2176066	hsa-miR-1322	CLIP-seq
MIRT799451	hsa-miR-2467-3p	CLIP-seq
MIRT799454	hsa-miR-3120-3p	CLIP-seq
MIRT2176067	hsa-miR-3144-5p	CLIP-seq
MIRT2176068	hsa-miR-3191	CLIP-seq
MIRT1936101	hsa-miR-3648	CLIP-seq
MIRT2176069	hsa-miR-3714	CLIP-seq
MIRT799474	hsa-miR-3919	CLIP-seq
MIRT799481	hsa-miR-4257	CLIP-seq
MIRT2176070	hsa-miR-431	CLIP-seq
MIRT1936125	hsa-miR-4434	CLIP-seq
MIRT799488	hsa-miR-4436b-3p	CLIP-seq
MIRT2176071	hsa-miR-4455	CLIP-seq
MIRT799491	hsa-miR-4457	CLIP-seq
MIRT799497	hsa-miR-4514	CLIP-seq
MIRT1936136	hsa-miR-4516	CLIP-seq
MIRT799498	hsa-miR-4643	CLIP-seq
MIRT2176072	hsa-miR-4652-5p	CLIP-seq
MIRT799504	hsa-miR-4667-5p	CLIP-seq
MIRT799508	hsa-miR-4692	CLIP-seq
MIRT799509	hsa-miR-4700-5p	CLIP-seq
MIRT1936151	hsa-miR-4705	CLIP-seq
MIRT1936155	hsa-miR-4723-5p	CLIP-seq
MIRT799513	hsa-miR-4731-3p	CLIP-seq
MIRT799516	hsa-miR-4763-3p	CLIP-seq
MIRT2176073	hsa-miR-4787-3p	CLIP-seq
MIRT799524	hsa-miR-4801	CLIP-seq
MIRT799525	hsa-miR-506	CLIP-seq
MIRT2176074	hsa-miR-511	CLIP-seq
MIRT2176075	hsa-miR-548a-3p	CLIP-seq
MIRT2176076	hsa-miR-548c-3p	CLIP-seq
MIRT2176077	hsa-miR-548e	CLIP-seq
MIRT2176078	hsa-miR-548f	CLIP-seq
MIRT799531	hsa-miR-637	CLIP-seq
MIRT1936202	hsa-miR-661	CLIP-seq
MIRT1936058	hsa-miR-138	CLIP-seq
MIRT799454	hsa-miR-3120-3p	CLIP-seq
MIRT799469	hsa-miR-370	CLIP-seq
MIRT2384484	hsa-miR-371b-3p	CLIP-seq
MIRT1936108	hsa-miR-3907	CLIP-seq
MIRT799491	hsa-miR-4457	CLIP-seq
MIRT1936140	hsa-miR-4639-3p	CLIP-seq
MIRT1936145	hsa-miR-4650-5p	CLIP-seq
MIRT1936153	hsa-miR-4716-5p	CLIP-seq
MIRT1936154	hsa-miR-4719	CLIP-seq
MIRT1936190	hsa-miR-548q	CLIP-seq
MIRT799536	hsa-miR-885-5p	CLIP-seq
MIRT1936072	hsa-miR-23a	CLIP-seq
MIRT1936073	hsa-miR-23b	CLIP-seq
MIRT1936074	hsa-miR-23c	CLIP-seq
MIRT2426485	hsa-miR-3653	CLIP-seq
MIRT2479418	hsa-miR-1470	CLIP-seq
MIRT1936111	hsa-miR-4252	CLIP-seq
MIRT2479419	hsa-miR-455-5p	CLIP-seq
MIRT2479420	hsa-miR-4667-3p	CLIP-seq
MIRT1936153	hsa-miR-4716-5p	CLIP-seq
MIRT2675392	hsa-miR-147	CLIP-seq
MIRT2675393	hsa-miR-3911	CLIP-seq
MIRT1936111	hsa-miR-4252	CLIP-seq
MIRT1936129	hsa-miR-4474-3p	CLIP-seq
MIRT2675394	hsa-miR-644	CLIP-seq

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Transcription factor	Regulation	Reference
HIF1A	Unknown	12239177

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	24465693
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0001666	Process	Response to hypoxia	IDA	12239177
GO:0001666	Process	Response to hypoxia	IEA
GO:0001701	Process	In utero embryonic development	IEA
GO:0001701	Process	In utero embryonic development	ISS
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0003700	Function	DNA-binding transcription factor activity	ISS
GO:0005515	Function	Protein binding	IPI	24465693, 24722188, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	12239177, 24465693
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	11782478
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007417	Process	Central nervous system development	IEA
GO:0007417	Process	Central nervous system development	ISS
GO:0007420	Process	Brain development	IMP	24022475
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0017162	Function	Aryl hydrocarbon receptor binding	IEA
GO:0017162	Function	Aryl hydrocarbon receptor binding	ISS
GO:0032355	Process	Response to estradiol	IEA
GO:0034751	Component	Aryl hydrocarbon receptor complex	IBA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	24465693
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046982	Function	Protein heterodimerization activity	IDA	24465693
GO:0046982	Function	Protein heterodimerization activity	IEA
GO:0046982	Function	Protein heterodimerization activity	IPI	12239177
GO:0046982	Function	Protein heterodimerization activity	ISS
GO:0046983	Function	Protein dimerization activity	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
606036	16876	ENSG00000172379

Q9HBZ2

Protein name

Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1)

Protein function

Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function (PubMed:24022475). Specifically recognizes the xenobiotic response element (XRE). {ECO:0000269|Pub

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00010	HLH	64 → 117	Helix-loop-helix DNA-binding domain	Domain
PF00989	PAS	137 → 244	PAS fold	Domain
PF08447	PAS_3	347 → 435	PAS fold	Domain

Sequence

MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGP
SKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTG
NKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFG
STLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICR
MRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEED
ADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGY
QPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTF
QNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSV
EKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSS
VVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGI
GTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESGQSSGQFQGRPSEVWSQW
QSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE

Sequence length

717

Interactions

View interactions

	KEGG		Reactome
	Pathways in cancer Transcriptional misregulation in cancer Renal cell carcinoma		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Webb-Dattani syndrome	Likely pathogenic; Pathogenic	rs1595993043, rs1596021185	RCV000986173 RCV000993667	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (14)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ARNT2-related disorder	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pulmonary disease, chronic obstructive, susceptibility to	association	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEPTO-OPTIC DYSPLASIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEPTO-OPTIC DYSPLASIA SPECTRUM	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEPTOOPTIC DYSPLASIA	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (67)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Agenesis of corpus callosum	Agenesis Of Corpus Callosum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial Fibrillation	CTD_human_DG	30061737		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorder	Autism	Pubtator	24736721	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	24736721		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Bone Diseases	Bone disease	Pubtator	40679635	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	21945317		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	21945317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital hypoplasia of penis	Congenital Hypoplasia Of Penis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptorchidism	Cryptorchidism	BEFREE	22648180		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptorchidism	Cryptorchidism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Depression Postpartum	Major depressive disorder	Pubtator	24022475	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Insipidus	Diabetes Insipidus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Dwarfism	Dwarfism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Dyssomnias	Dyssomnia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Atresia	Esophageal Atresia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastroesophageal reflux disease	Gastroesophageal Reflux Disease	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	29149419		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	29149419		★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hemiplegia/hemiparesis	Hemiplegia/hemiparesis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hirschsprung Disease	Hirschsprung Disease	BEFREE	20977903		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hydronephrosis	Hydronephrosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypohidrosis	Hypohidrosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypopituitarism	Hypopituitarism	BEFREE	24022475		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypopituitarism	Hypopituitarism	Pubtator	24022475	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoplasia of corpus callosum	Hypoplasia Of Corpus Callosum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypospadias	Hypospadias	BEFREE	22648180, 23285176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypospadias	Hypospadias	Pubtator	23285176	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	12239177	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Isolated somatotropin deficiency	Isolated Somatotropin Deficiency	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Kallmann Syndrome	Kallmann Syndrome	ORPHANET_DG	24022475		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25611915		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	21945317		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	29948506		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	17899366		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	35606887	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	30231889		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	36203533	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20709796, 25611915, 25613063, 29149419, 29948506, 30305224		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	12239177	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	20977903		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurogenic Urinary Bladder	Neurogenic Urinary Bladder	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	25613063		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nystagmus	Nystagmus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	30563851		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	34214899	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Paroxysmal atrial fibrillation	Paroxysmal atrial fibrillation	CTD_human_DG	30061737		★★★★★ ★☆☆☆☆ Found in Text Mining only
Penile hypospadias	Penile Hypospadias	BEFREE	22648180, 23285176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinal Diseases	Retinal detachment	Pubtator	24022475	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	24736721		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	24736721	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Secondary hypothyroidism	Hypothyroidism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Sensorineural Hearing Loss (disorder)	Hearing Loss	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Septo-Optic Dysplasia	Septo-Optic Dysplasia	ORPHANET_DG	24022475		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Septo-Optic Dysplasia	Septo-Optic Dysplasia	HPO_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Septo-optic dysplasia spectrum	Septo-Optic Dysplasia	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sleep Disorders	Sleep Disorders	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Somatotropin deficiency	Somatotropin Deficiency	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	29948506		★★★★★ ★☆☆☆☆ Found in Text Mining only
Strabismus	Strabismus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Vesico-Ureteral Reflux	Vesicoureteral Reflux	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Vision Disorders	Visual disorder	Pubtator	24022475	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
WEBB-DATTANI SYNDROME	Webb-Dattani Syndrome	GENOMICS_ENGLAND_DG	24022475		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
WEBB-DATTANI SYNDROME	Webb-Dattani Syndrome	CTD_human_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

ARNT2 (aryl hydrocarbon receptor nuclear translocator 2)