Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Other IDs Protein Associated diseases
Entrez ID	9881
Gene name	Tetratricopeptide repeat and ankyrin repeat containing 1
Gene symbol	TRANK1
Synonyms (NCBI Gene)	LBA1
Chromosome	3
Chromosome location	3p22.2

116

Show/Hide all (116)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018157	hsa-miR-335-5p	Microarray	18185580
MIRT029736	hsa-miR-26b-5p	Microarray	19088304
MIRT1451652	hsa-miR-1202	CLIP-seq
MIRT1451653	hsa-miR-1255a	CLIP-seq
MIRT1451654	hsa-miR-1255b	CLIP-seq
MIRT1451655	hsa-miR-1297	CLIP-seq
MIRT1451656	hsa-miR-1343	CLIP-seq
MIRT1451657	hsa-miR-23a	CLIP-seq
MIRT1451658	hsa-miR-23b	CLIP-seq
MIRT1451659	hsa-miR-23c	CLIP-seq
MIRT1451660	hsa-miR-26a	CLIP-seq
MIRT1451661	hsa-miR-26b	CLIP-seq
MIRT1451662	hsa-miR-28-3p	CLIP-seq
MIRT1451663	hsa-miR-3074-5p	CLIP-seq
MIRT1451664	hsa-miR-3126-5p	CLIP-seq
MIRT1451665	hsa-miR-3133	CLIP-seq
MIRT1451666	hsa-miR-3136-3p	CLIP-seq
MIRT1451667	hsa-miR-3202	CLIP-seq
MIRT1451668	hsa-miR-3662	CLIP-seq
MIRT1451669	hsa-miR-3972	CLIP-seq
MIRT1451670	hsa-miR-3976	CLIP-seq
MIRT1451671	hsa-miR-4270	CLIP-seq
MIRT1451672	hsa-miR-4419a	CLIP-seq
MIRT1451673	hsa-miR-4441	CLIP-seq
MIRT1451674	hsa-miR-4450	CLIP-seq
MIRT1451675	hsa-miR-4465	CLIP-seq
MIRT1451676	hsa-miR-4475	CLIP-seq
MIRT1451677	hsa-miR-4510	CLIP-seq
MIRT1451678	hsa-miR-4652-3p	CLIP-seq
MIRT1451679	hsa-miR-4747-5p	CLIP-seq
MIRT1451680	hsa-miR-4755-3p	CLIP-seq
MIRT1451681	hsa-miR-4760-3p	CLIP-seq
MIRT1451682	hsa-miR-576-3p	CLIP-seq
MIRT1451683	hsa-miR-589	CLIP-seq
MIRT2135203	hsa-miR-1	CLIP-seq
MIRT2135204	hsa-miR-1184	CLIP-seq
MIRT2135205	hsa-miR-1205	CLIP-seq
MIRT2135206	hsa-miR-1207-5p	CLIP-seq
MIRT1451653	hsa-miR-1255a	CLIP-seq
MIRT1451654	hsa-miR-1255b	CLIP-seq
MIRT2135207	hsa-miR-1301	CLIP-seq
MIRT2135208	hsa-miR-143	CLIP-seq
MIRT2135209	hsa-miR-15a	CLIP-seq
MIRT2135210	hsa-miR-15b	CLIP-seq
MIRT2135211	hsa-miR-16	CLIP-seq
MIRT2135212	hsa-miR-195	CLIP-seq
MIRT2135213	hsa-miR-204	CLIP-seq
MIRT2135214	hsa-miR-206	CLIP-seq
MIRT2135215	hsa-miR-211	CLIP-seq
MIRT2135216	hsa-miR-224	CLIP-seq
MIRT1451664	hsa-miR-3126-5p	CLIP-seq
MIRT2135217	hsa-miR-3150b-3p	CLIP-seq
MIRT2135218	hsa-miR-3170	CLIP-seq
MIRT2135219	hsa-miR-3670	CLIP-seq
MIRT2135220	hsa-miR-3673	CLIP-seq
MIRT2135221	hsa-miR-3688-5p	CLIP-seq
MIRT2135222	hsa-miR-3938	CLIP-seq
MIRT2135223	hsa-miR-424	CLIP-seq
MIRT2135224	hsa-miR-4263	CLIP-seq
MIRT2135225	hsa-miR-4302	CLIP-seq
MIRT1451672	hsa-miR-4419a	CLIP-seq
MIRT1451677	hsa-miR-4510	CLIP-seq
MIRT2135226	hsa-miR-4519	CLIP-seq
MIRT2135227	hsa-miR-4660	CLIP-seq
MIRT2135228	hsa-miR-4671-5p	CLIP-seq
MIRT2135229	hsa-miR-4689	CLIP-seq
MIRT2135230	hsa-miR-4722-5p	CLIP-seq
MIRT2135231	hsa-miR-4736	CLIP-seq
MIRT2135232	hsa-miR-4755-5p	CLIP-seq
MIRT2135233	hsa-miR-4763-3p	CLIP-seq
MIRT2135234	hsa-miR-4768-3p	CLIP-seq
MIRT2135235	hsa-miR-4770	CLIP-seq
MIRT2135236	hsa-miR-4784	CLIP-seq
MIRT2135237	hsa-miR-497	CLIP-seq
MIRT2135238	hsa-miR-5047	CLIP-seq
MIRT2135239	hsa-miR-545	CLIP-seq
MIRT2135240	hsa-miR-613	CLIP-seq
MIRT2135241	hsa-miR-623	CLIP-seq
MIRT2135242	hsa-miR-625	CLIP-seq
MIRT2135243	hsa-miR-644	CLIP-seq
MIRT2135206	hsa-miR-1207-5p	CLIP-seq
MIRT2135208	hsa-miR-143	CLIP-seq
MIRT2356354	hsa-miR-149	CLIP-seq
MIRT2135209	hsa-miR-15a	CLIP-seq
MIRT2135210	hsa-miR-15b	CLIP-seq
MIRT2135211	hsa-miR-16	CLIP-seq
MIRT2135212	hsa-miR-195	CLIP-seq
MIRT1451664	hsa-miR-3126-5p	CLIP-seq
MIRT2135221	hsa-miR-3688-5p	CLIP-seq
MIRT2135223	hsa-miR-424	CLIP-seq
MIRT2135225	hsa-miR-4302	CLIP-seq
MIRT1451672	hsa-miR-4419a	CLIP-seq
MIRT1451677	hsa-miR-4510	CLIP-seq
MIRT2135230	hsa-miR-4722-5p	CLIP-seq
MIRT2135231	hsa-miR-4736	CLIP-seq
MIRT2135233	hsa-miR-4763-3p	CLIP-seq
MIRT2135234	hsa-miR-4768-3p	CLIP-seq
MIRT2135235	hsa-miR-4770	CLIP-seq
MIRT2135237	hsa-miR-497	CLIP-seq
MIRT2135239	hsa-miR-545	CLIP-seq
MIRT2356355	hsa-miR-548p	CLIP-seq
MIRT2135243	hsa-miR-644	CLIP-seq
MIRT2135206	hsa-miR-1207-5p	CLIP-seq
MIRT2135208	hsa-miR-143	CLIP-seq
MIRT1451664	hsa-miR-3126-5p	CLIP-seq
MIRT2135221	hsa-miR-3688-5p	CLIP-seq
MIRT2135225	hsa-miR-4302	CLIP-seq
MIRT1451672	hsa-miR-4419a	CLIP-seq
MIRT1451677	hsa-miR-4510	CLIP-seq
MIRT2135226	hsa-miR-4519	CLIP-seq
MIRT2135230	hsa-miR-4722-5p	CLIP-seq
MIRT2135231	hsa-miR-4736	CLIP-seq
MIRT2135233	hsa-miR-4763-3p	CLIP-seq
MIRT2135234	hsa-miR-4768-3p	CLIP-seq
MIRT2135235	hsa-miR-4770	CLIP-seq
MIRT2135243	hsa-miR-644	CLIP-seq

MIM	HGNC	e!Ensembl
619316	29011	ENSG00000168016

O15050

Protein name

TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog)

Family and domains

Sequence

MWDPRAARVPPRDLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLL
RLHQPYEAARMFFEGLRLVQRSQDQAPVADFLVGVFTTMSSDSIVLQSFLPCFDHIFTTG
FPTEVWQSVIEKLAKKGLWHSFLLLSAKKDRLPRNIHVPELSLKSLFEKYVFIGLYEKME
QVPKLVQWLISIGASVETIGPYPLHALMRLCIQARENHLFRWLMDHKPEWKGRINQKDGD
GCTVLHVVAAHSPGYLVKRQTEDVQMLLRFGADPTLLDRQSRSVVDVLKRNKNFKAIEKI
NSHLEKLATCSKDLSGFSNGDGPTSENDIFRKVLEQLVKYMNSGNRLLHKNFLKQEVVQR
FLRLLSTLQEIPPDLVCDINQDCATTVFKFLLEKQRWPEVLLLLTRKVSGEPPLGDCLIK
DCNFSDLDICTIIPHLSTWDQRKKQLLGCLIDSGALPDGLQESQERPVVTCLKHEDFELA
FLLLTKGADPRAISLTEGDTPLHAALHIFLEIKADIGFSFLSHLLDLFWSNPTEFDYLNP
NVQDSNGNTLMHILFQKGMLKRVKKLLDLLVKFDINFNLKNKEGKDARHRIKKNDSLLLA
WNKALMENRRRSRQDSAAHLGKLSKSTAPGHTSQLKSQGSFKSVPCGATARTLPEGSAVP
DSWETLPGTQVTRKEPGALRPCSLRDCLMQDITVLIQQVEVDPSFPEDCLQSSEPLEAGA
GKEGKKDDKPTLGAGAPDCSEVGEGHAQVGLGALQLVPDDNRGKEGNDDQDDWSTQEIEA
CLQDFDNMTWEIECTSEMLKKLSSKVMTKVIKKKIILAIQQLGNGEWTQGLQKRLKHLKG
SIQLFEAKLDKGARMLWELAIDFSPRCSENPEKIIATEQNTCAMEKSGRIYTEIIRIWDI
VLDHCKLADSIKAICNAYNRGLSCVLRKKLKGINKGQVSANMKIQKRIPRCYVEDTEAEK
GREHVNPEYFPPASAVETEYNIMKFHSFSTNMAFNILNDTTATVEYPFRVGELEYAVIDL
NPRPLEPIILIGRSGTGKTTCCLYRLWKKFHVYWEKAEQAGSPLLAKQVWLKRRLEVEPG
KESPGGEEEEEEEDEEEEDSIEVETVESIDEQEYEACAGGAGVEPAGDGQAAEVCAPEHP
HQLEHLHQIFVTKNHVLCQEVQRNFIELSKSTKATSHYKPLDPNIHKLQDLRDENFPLFV
TSKQLLLLLDASLPKPFFLRNEDGSLKRTIIGWSAQEESTIPSWQEDEEEAEVDGDYSEE
DKAVEMRTGDSDPRVYVTFEVFKNEIWPKMTKGRTAYNPALIWKEIKSFLKGSFEALSCP
HGRLTEEVYKKLGRKRCPNFKEDRSEIYSLFSLYQQIRSQKGYFDEEDVLYNISRRLSKL
RVLPWSIHELYGDEIQDFTQAELALLMKCINDPNSMFLTGDTAQSIMKGVAFRFSDLRSL
FHYASRNTIDKQCAVRKPKKIHQLYQNYRSHSGILNLASGVVDLLQFYFPESFDRLPRDS
GLFDGPKPTVLESCSVSDLAILLRGNKRKTQPIEFGAHQVILVANETAKEKIPEELGLAL
VLTIYEAKGLEFDDVLLYNFFTDSEAYKEWKIISSFTPTSTDSREENRPLVEVPLDKPGS
SQGRSLMVNPEMYKLLNGELKQLYTAITRARVNLWIFDENREKRAPAFKYFIRRDFVQVV
KTDENKDFDDSMFVKTSTPAEWIAQGDYYAKHQCWKVAAKCYQKGGAFEKEKLALAHDTA
LSMKSKKVSPKEKQLEYLELAKTYLECKEPTLSLKCLSYAKEFQLSAQLCERLGKIRDAA
YFYKRSQCYKDAFRCFEQIQEFDLALKMYCQEELFEEAAIAVEKYEEMLKTKTLPISKLS
YSASQFYLEAAAKYLSANKMKEMMAVLSKLDIEDQLVFLKSRKRLAEAADLLNREGRREE
AALLMKQHGCLLEAARLTADKDFQASCLLGAARLNVARDSDIEHTKDILREALDICYQTG
QLSGIAEAHFLQGVILRDFQKLRDAFFKFDTLNHSAGVVEALYEAASQCEAEPEKILGLA
PGGLEILLSLVRALKRVTNNAEKEMVKSCFEFFGISQVDAKYCQIAQNDPGPILRIIFDL
DLNLREKKTKDHFLIMTDQVKLALNKHLLGRLCQITRSLLGKTYRGVCMRFIVGLKCEDE
NCEHFHRPLRRCEAKCLVQSKMNLVAINGLLLEAKKVFPKILAEELKEIDYILSTDMYGL
CKSILDVLFPKHFHQRVLSENPMACKEILKPNYKSFRFYRFALKEYIHFLFENESARNRR
ESTDLWLSAMQAFLLSSNYPEEFEKLLHQEEDNYNRELKALESEKDERGRGRGSRIKGIE
GKFGMLAPNRDDENMDKTHLCFIRLLENCIDQFYVYRNPEDYKRLFFRFMNVLIKRCKEP
LIPSIGNTVALLEFQFIHCGVVLARLWKNVILCLPKSYIALLHYWEFLFSKKDKELGDVF
SIIQEYKPKDVTRAIQDFRFHLSYLAKVLCGYENVNFNVLLDAFSEIDYVVSGEAERTLV
LCLVMLVNAEEILQPYCKPLLYRHFREIESRLQLMSMDCPGQVPERLLKVVKRVLVAVNV
KSVAEALQDLLFERDEEYLMDCDWRWDPVHTKGSIVRGLYYEEVRLNRLLCLDPVDYFAE
PECEFGQDEMDELALEDRDHVLATILSQKQRKASIQRKLRRACLVVSLCISWRRRVGTQM
ERVREEAREPRAGNFKKADVDRTQCDLCGVKFTRGPENYFSPSKAFEGAASEVAVLSRAE
LEREECQERNSESYEQHIHLEHHQRQQVAYQKYSEFFHEKVDPAIDEGKLVVQDIEQSVW
IHSHVGSKEHSHMLQKVQEHIKRVSDMVEDLYRRKAWAGAEEAMTRLVNILILSVRDARD
WLMKTETRLKKEGIVQEDDYENEVEDFGELRPRRRSRKCGKQRKY

Sequence length

2925

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (16)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism spectrum disorder	association	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISTIC DISORDER	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BILIRUBIN METABOLISM DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	CTD, Disgenet, GWAS catalog CTD, Disgenet, GWAS catalog CTD, Disgenet, GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEPRESSION, BIPOLAR	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOTHYROIDISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KLEINE-LEVIN SYNDROME	—	Disgenet, Orphanet Disgenet, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIXED BIPOLAR I DISORDER	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (13)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Bipolar Disorder	Bipolar Disorder	GWASDB_DG	22182935, 24618891		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar disorder	Pubtator	24280982, 24618891, 28115744, 28166306, 33737391, 40562893	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	BEFREE	28115744, 28166306		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	CTD_human_DG	31043756		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	26474971	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Depression, Bipolar	Bipolar Disorder	CTD_human_DG	31043756		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypothyroidism	Hypothyroidism	GWASCAT_DG	30595370		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Manic	Manic Disorder	CTD_human_DG	31043756		★★★★★ ★☆☆☆☆ Found in Text Mining only
Manic Disorder	Manic Disorder	CTD_human_DG	31043756		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	BEFREE	30135510		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	28991256, 30285260		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	BEFREE	29373732		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	Pubtator	33737391	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1)