SLK (STE20 like kinase)

Gene

• Entrez ID: 9748
• Gene name: STE20 like kinase
• Gene symbol: SLK
• Synonyms (NCBI Gene): LOSK, STK2, bA16H23.1, se20-9
• Chromosome: 10
• Chromosome location: 10q24.33-q25.1

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1589547463	C>T	Likely-pathogenic	Coding sequence variant, stop gained

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT031072	hsa-miR-21-5p	Microarray	20371350
MIRT031072	hsa-miR-21-5p	Microarray	18591254
MIRT051774	hsa-let-7c-5p	CLASH	23622248
MIRT042026	hsa-miR-484	CLASH	23622248
MIRT040336	hsa-miR-615-3p	CLASH	23622248
MIRT439592	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439590	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439592	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT726498	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT726497	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT726496	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT726495	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439590	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT1369830	hsa-miR-101	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT1369833	hsa-miR-1207-5p	CLIP-seq
MIRT1369834	hsa-miR-1245	CLIP-seq
MIRT1369835	hsa-miR-1265	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369837	hsa-miR-132	CLIP-seq
MIRT1369838	hsa-miR-144	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT1369840	hsa-miR-181a	CLIP-seq
MIRT1369841	hsa-miR-181b	CLIP-seq
MIRT1369842	hsa-miR-181c	CLIP-seq
MIRT1369843	hsa-miR-181d	CLIP-seq
MIRT1369844	hsa-miR-194	CLIP-seq
MIRT1369845	hsa-miR-200b	CLIP-seq
MIRT1369846	hsa-miR-200c	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369849	hsa-miR-212	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369853	hsa-miR-2392	CLIP-seq
MIRT1369854	hsa-miR-29a	CLIP-seq
MIRT1369855	hsa-miR-29b	CLIP-seq
MIRT1369856	hsa-miR-29c	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT1369862	hsa-miR-3124-3p	CLIP-seq
MIRT1369863	hsa-miR-3129-3p	CLIP-seq
MIRT1369864	hsa-miR-3149	CLIP-seq
MIRT1369865	hsa-miR-3161	CLIP-seq
MIRT1369866	hsa-miR-3163	CLIP-seq
MIRT1369867	hsa-miR-3171	CLIP-seq
MIRT1369868	hsa-miR-3187-3p	CLIP-seq
MIRT1369869	hsa-miR-340	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT1369871	hsa-miR-3606	CLIP-seq
MIRT1369872	hsa-miR-3607-5p	CLIP-seq
MIRT1369873	hsa-miR-3622a-5p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369875	hsa-miR-365	CLIP-seq
MIRT1369876	hsa-miR-3653	CLIP-seq
MIRT1369877	hsa-miR-3658	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT1369879	hsa-miR-3689a-5p	CLIP-seq
MIRT1369880	hsa-miR-3689b	CLIP-seq
MIRT1369881	hsa-miR-3689e	CLIP-seq
MIRT1369882	hsa-miR-3689f	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT1369885	hsa-miR-374c	CLIP-seq
MIRT1369886	hsa-miR-377	CLIP-seq
MIRT1369887	hsa-miR-382	CLIP-seq
MIRT1369888	hsa-miR-410	CLIP-seq
MIRT1369889	hsa-miR-4262	CLIP-seq
MIRT1369890	hsa-miR-4275	CLIP-seq
MIRT1369891	hsa-miR-4282	CLIP-seq
MIRT1369892	hsa-miR-429	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT1369895	hsa-miR-4328	CLIP-seq
MIRT1369896	hsa-miR-4423-3p	CLIP-seq
MIRT1369897	hsa-miR-4435	CLIP-seq
MIRT1369898	hsa-miR-4477a	CLIP-seq
MIRT1369899	hsa-miR-4514	CLIP-seq
MIRT1369900	hsa-miR-4539	CLIP-seq
MIRT1369901	hsa-miR-4643	CLIP-seq
MIRT1369902	hsa-miR-4666-5p	CLIP-seq
MIRT1369903	hsa-miR-4670-3p	CLIP-seq
MIRT1369904	hsa-miR-4692	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT1369906	hsa-miR-4699-5p	CLIP-seq
MIRT1369907	hsa-miR-4701-5p	CLIP-seq
MIRT1369908	hsa-miR-4719	CLIP-seq
MIRT1369909	hsa-miR-4736	CLIP-seq
MIRT1369910	hsa-miR-4762-3p	CLIP-seq
MIRT1369911	hsa-miR-4762-5p	CLIP-seq
MIRT1369912	hsa-miR-4763-3p	CLIP-seq
MIRT1369913	hsa-miR-4775	CLIP-seq
MIRT1369914	hsa-miR-4778-5p	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT1369916	hsa-miR-495	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT1369918	hsa-miR-513b	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT1369925	hsa-miR-548l	CLIP-seq
MIRT1369926	hsa-miR-548n	CLIP-seq
MIRT1369927	hsa-miR-548s	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369929	hsa-miR-553	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT1369931	hsa-miR-568	CLIP-seq
MIRT1369932	hsa-miR-583	CLIP-seq
MIRT1369933	hsa-miR-586	CLIP-seq
MIRT1369934	hsa-miR-588	CLIP-seq
MIRT1369935	hsa-miR-595	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT1369938	hsa-miR-630	CLIP-seq
MIRT1369939	hsa-miR-651	CLIP-seq
MIRT1369940	hsa-miR-655	CLIP-seq
MIRT1369941	hsa-miR-802	CLIP-seq
MIRT1369942	hsa-miR-921	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT1369944	hsa-miR-944	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT2109787	hsa-miR-186	CLIP-seq
MIRT2109788	hsa-miR-197	CLIP-seq
MIRT1369845	hsa-miR-200b	CLIP-seq
MIRT1369846	hsa-miR-200c	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT1369862	hsa-miR-3124-3p	CLIP-seq
MIRT2109790	hsa-miR-3133	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT2109791	hsa-miR-371b-5p	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2109794	hsa-miR-4274	CLIP-seq
MIRT1369892	hsa-miR-429	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT1369895	hsa-miR-4328	CLIP-seq
MIRT2109795	hsa-miR-4420	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2109798	hsa-miR-4509	CLIP-seq
MIRT2109799	hsa-miR-4519	CLIP-seq
MIRT1369902	hsa-miR-4666-5p	CLIP-seq
MIRT2109800	hsa-miR-4709-5p	CLIP-seq
MIRT2109801	hsa-miR-4733-3p	CLIP-seq
MIRT2109802	hsa-miR-4744	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT2109803	hsa-miR-5096	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT2109804	hsa-miR-515-5p	CLIP-seq
MIRT1369926	hsa-miR-548n	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT1369830	hsa-miR-101	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT1369834	hsa-miR-1245	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT2333203	hsa-miR-1276	CLIP-seq
MIRT1369838	hsa-miR-144	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT1369840	hsa-miR-181a	CLIP-seq
MIRT1369841	hsa-miR-181b	CLIP-seq
MIRT1369842	hsa-miR-181c	CLIP-seq
MIRT1369843	hsa-miR-181d	CLIP-seq
MIRT2109787	hsa-miR-186	CLIP-seq
MIRT1369844	hsa-miR-194	CLIP-seq
MIRT2109788	hsa-miR-197	CLIP-seq
MIRT1369845	hsa-miR-200b	CLIP-seq
MIRT1369846	hsa-miR-200c	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2333204	hsa-miR-204	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT2333205	hsa-miR-211	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT2333206	hsa-miR-224	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT2333207	hsa-miR-300	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT2333208	hsa-miR-3120-5p	CLIP-seq
MIRT2109790	hsa-miR-3133	CLIP-seq
MIRT2333209	hsa-miR-3140-5p	CLIP-seq
MIRT1369864	hsa-miR-3149	CLIP-seq
MIRT1369865	hsa-miR-3161	CLIP-seq
MIRT1369867	hsa-miR-3171	CLIP-seq
MIRT2333210	hsa-miR-329	CLIP-seq
MIRT1369871	hsa-miR-3606	CLIP-seq
MIRT1369872	hsa-miR-3607-5p	CLIP-seq
MIRT2333211	hsa-miR-362-3p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369879	hsa-miR-3689a-5p	CLIP-seq
MIRT1369880	hsa-miR-3689b	CLIP-seq
MIRT1369881	hsa-miR-3689e	CLIP-seq
MIRT1369882	hsa-miR-3689f	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT1369885	hsa-miR-374c	CLIP-seq
MIRT2333212	hsa-miR-381	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT1369888	hsa-miR-410	CLIP-seq
MIRT1369889	hsa-miR-4262	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2109794	hsa-miR-4274	CLIP-seq
MIRT1369892	hsa-miR-429	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT1369895	hsa-miR-4328	CLIP-seq
MIRT2333213	hsa-miR-4427	CLIP-seq
MIRT2333214	hsa-miR-4446-5p	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT1369898	hsa-miR-4477a	CLIP-seq
MIRT2109798	hsa-miR-4509	CLIP-seq
MIRT2109799	hsa-miR-4519	CLIP-seq
MIRT2333215	hsa-miR-466	CLIP-seq
MIRT2333216	hsa-miR-4666-3p	CLIP-seq
MIRT2333217	hsa-miR-4672	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT2109800	hsa-miR-4709-5p	CLIP-seq
MIRT2109801	hsa-miR-4733-3p	CLIP-seq
MIRT2109802	hsa-miR-4744	CLIP-seq
MIRT2333218	hsa-miR-4755-5p	CLIP-seq
MIRT1369911	hsa-miR-4762-5p	CLIP-seq
MIRT2333219	hsa-miR-4766-5p	CLIP-seq
MIRT2333220	hsa-miR-4776-3p	CLIP-seq
MIRT2333221	hsa-miR-4793-5p	CLIP-seq
MIRT2109803	hsa-miR-5096	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT2109804	hsa-miR-515-5p	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT2333222	hsa-miR-520d-5p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT2333223	hsa-miR-524-5p	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT1369931	hsa-miR-568	CLIP-seq
MIRT1369935	hsa-miR-595	CLIP-seq
MIRT2333224	hsa-miR-603	CLIP-seq
MIRT2333225	hsa-miR-623	CLIP-seq
MIRT2333226	hsa-miR-634	CLIP-seq
MIRT1369940	hsa-miR-655	CLIP-seq
MIRT1369941	hsa-miR-802	CLIP-seq
MIRT1369942	hsa-miR-921	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT2394846	hsa-miR-145	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2333208	hsa-miR-3120-5p	CLIP-seq
MIRT2394847	hsa-miR-3180-5p	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2394848	hsa-miR-450b-5p	CLIP-seq
MIRT2333220	hsa-miR-4776-3p	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT1369830	hsa-miR-101	CLIP-seq
MIRT2433313	hsa-miR-1260	CLIP-seq
MIRT2433314	hsa-miR-1260b	CLIP-seq
MIRT1369838	hsa-miR-144	CLIP-seq
MIRT1369840	hsa-miR-181a	CLIP-seq
MIRT1369841	hsa-miR-181b	CLIP-seq
MIRT1369842	hsa-miR-181c	CLIP-seq
MIRT1369843	hsa-miR-181d	CLIP-seq
MIRT2433315	hsa-miR-188-3p	CLIP-seq
MIRT2433316	hsa-miR-3156-3p	CLIP-seq
MIRT1369865	hsa-miR-3161	CLIP-seq
MIRT1369872	hsa-miR-3607-5p	CLIP-seq
MIRT1369879	hsa-miR-3689a-5p	CLIP-seq
MIRT1369880	hsa-miR-3689b	CLIP-seq
MIRT1369881	hsa-miR-3689e	CLIP-seq
MIRT1369882	hsa-miR-3689f	CLIP-seq
MIRT2433317	hsa-miR-4255	CLIP-seq
MIRT1369889	hsa-miR-4262	CLIP-seq
MIRT2433318	hsa-miR-4517	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT1369935	hsa-miR-595	CLIP-seq
MIRT1369941	hsa-miR-802	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT2627411	hsa-miR-103b	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT2433313	hsa-miR-1260	CLIP-seq
MIRT2433314	hsa-miR-1260b	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT2627412	hsa-miR-185	CLIP-seq
MIRT2433315	hsa-miR-188-3p	CLIP-seq
MIRT2109788	hsa-miR-197	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2627413	hsa-miR-2052	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369854	hsa-miR-29a	CLIP-seq
MIRT1369855	hsa-miR-29b	CLIP-seq
MIRT1369856	hsa-miR-29c	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT2627414	hsa-miR-3119	CLIP-seq
MIRT2627415	hsa-miR-3155	CLIP-seq
MIRT2627416	hsa-miR-3155b	CLIP-seq
MIRT2433316	hsa-miR-3156-3p	CLIP-seq
MIRT2627417	hsa-miR-3160-3p	CLIP-seq
MIRT2333210	hsa-miR-329	CLIP-seq
MIRT2627418	hsa-miR-338-5p	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT2627419	hsa-miR-3591-5p	CLIP-seq
MIRT1369873	hsa-miR-3622a-5p	CLIP-seq
MIRT2333211	hsa-miR-362-3p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369876	hsa-miR-3653	CLIP-seq
MIRT1369877	hsa-miR-3658	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT2109791	hsa-miR-371b-5p	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT2627420	hsa-miR-421	CLIP-seq
MIRT2433317	hsa-miR-4255	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2627421	hsa-miR-4267	CLIP-seq
MIRT1369890	hsa-miR-4275	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT2627422	hsa-miR-4301	CLIP-seq
MIRT2627423	hsa-miR-4302	CLIP-seq
MIRT2627424	hsa-miR-4306	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT2109795	hsa-miR-4420	CLIP-seq
MIRT1369896	hsa-miR-4423-3p	CLIP-seq
MIRT2627425	hsa-miR-4426	CLIP-seq
MIRT2333214	hsa-miR-4446-5p	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2627426	hsa-miR-4484	CLIP-seq
MIRT2433318	hsa-miR-4517	CLIP-seq
MIRT2627427	hsa-miR-4534	CLIP-seq
MIRT2627428	hsa-miR-4644	CLIP-seq
MIRT2627429	hsa-miR-4647	CLIP-seq
MIRT2333215	hsa-miR-466	CLIP-seq
MIRT2627430	hsa-miR-4662b	CLIP-seq
MIRT2333217	hsa-miR-4672	CLIP-seq
MIRT2627431	hsa-miR-4678	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT2109800	hsa-miR-4709-5p	CLIP-seq
MIRT2627432	hsa-miR-4712-3p	CLIP-seq
MIRT2627433	hsa-miR-4729	CLIP-seq
MIRT2109801	hsa-miR-4733-3p	CLIP-seq
MIRT2627434	hsa-miR-4733-5p	CLIP-seq
MIRT2627435	hsa-miR-4753-3p	CLIP-seq
MIRT1369911	hsa-miR-4762-5p	CLIP-seq
MIRT2627436	hsa-miR-4768-5p	CLIP-seq
MIRT1369913	hsa-miR-4775	CLIP-seq
MIRT2627437	hsa-miR-4795-3p	CLIP-seq
MIRT2627438	hsa-miR-4797-5p	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT2627439	hsa-miR-487a	CLIP-seq
MIRT2627440	hsa-miR-505	CLIP-seq
MIRT2109803	hsa-miR-5096	CLIP-seq
MIRT1369917	hsa-miR-513a-3p	CLIP-seq
MIRT2627441	hsa-miR-514	CLIP-seq
MIRT2627442	hsa-miR-514b-3p	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT2627443	hsa-miR-539	CLIP-seq
MIRT2627444	hsa-miR-548an	CLIP-seq
MIRT1369926	hsa-miR-548n	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT2627445	hsa-miR-576-5p	CLIP-seq
MIRT1369932	hsa-miR-583	CLIP-seq
MIRT2627446	hsa-miR-590-3p	CLIP-seq
MIRT2333224	hsa-miR-603	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT2627447	hsa-miR-616	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT2333226	hsa-miR-634	CLIP-seq
MIRT2627448	hsa-miR-640	CLIP-seq
MIRT2627449	hsa-miR-888	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT1369944	hsa-miR-944	CLIP-seq
MIRT1369831	hsa-miR-106a	CLIP-seq
MIRT1369832	hsa-miR-106b	CLIP-seq
MIRT2109785	hsa-miR-1226	CLIP-seq
MIRT2433313	hsa-miR-1260	CLIP-seq
MIRT2433314	hsa-miR-1260b	CLIP-seq
MIRT2691345	hsa-miR-1263	CLIP-seq
MIRT2109786	hsa-miR-1273g	CLIP-seq
MIRT1369836	hsa-miR-1305	CLIP-seq
MIRT1369839	hsa-miR-17	CLIP-seq
MIRT2627412	hsa-miR-185	CLIP-seq
MIRT2433315	hsa-miR-188-3p	CLIP-seq
MIRT2109789	hsa-miR-203	CLIP-seq
MIRT2627413	hsa-miR-2052	CLIP-seq
MIRT1369847	hsa-miR-20a	CLIP-seq
MIRT1369848	hsa-miR-20b	CLIP-seq
MIRT1369850	hsa-miR-221	CLIP-seq
MIRT1369851	hsa-miR-222	CLIP-seq
MIRT1369852	hsa-miR-2276	CLIP-seq
MIRT1369854	hsa-miR-29a	CLIP-seq
MIRT1369855	hsa-miR-29b	CLIP-seq
MIRT1369856	hsa-miR-29c	CLIP-seq
MIRT1369857	hsa-miR-302a	CLIP-seq
MIRT1369858	hsa-miR-302b	CLIP-seq
MIRT1369859	hsa-miR-302c	CLIP-seq
MIRT1369860	hsa-miR-302d	CLIP-seq
MIRT1369861	hsa-miR-302e	CLIP-seq
MIRT2627414	hsa-miR-3119	CLIP-seq
MIRT2627415	hsa-miR-3155	CLIP-seq
MIRT2627416	hsa-miR-3155b	CLIP-seq
MIRT2433316	hsa-miR-3156-3p	CLIP-seq
MIRT2333210	hsa-miR-329	CLIP-seq
MIRT1369870	hsa-miR-34b	CLIP-seq
MIRT2627419	hsa-miR-3591-5p	CLIP-seq
MIRT1369873	hsa-miR-3622a-5p	CLIP-seq
MIRT2333211	hsa-miR-362-3p	CLIP-seq
MIRT1369874	hsa-miR-3647-3p	CLIP-seq
MIRT1369876	hsa-miR-3653	CLIP-seq
MIRT1369877	hsa-miR-3658	CLIP-seq
MIRT1369878	hsa-miR-3671	CLIP-seq
MIRT1369883	hsa-miR-372	CLIP-seq
MIRT1369884	hsa-miR-373	CLIP-seq
MIRT2109792	hsa-miR-3941	CLIP-seq
MIRT2433317	hsa-miR-4255	CLIP-seq
MIRT2109793	hsa-miR-4263	CLIP-seq
MIRT2627421	hsa-miR-4267	CLIP-seq
MIRT1369890	hsa-miR-4275	CLIP-seq
MIRT1369893	hsa-miR-4291	CLIP-seq
MIRT2627422	hsa-miR-4301	CLIP-seq
MIRT2627423	hsa-miR-4302	CLIP-seq
MIRT2627424	hsa-miR-4306	CLIP-seq
MIRT1369894	hsa-miR-4310	CLIP-seq
MIRT2109795	hsa-miR-4420	CLIP-seq
MIRT1369896	hsa-miR-4423-3p	CLIP-seq
MIRT2627425	hsa-miR-4426	CLIP-seq
MIRT2333214	hsa-miR-4446-5p	CLIP-seq
MIRT2109796	hsa-miR-4462	CLIP-seq
MIRT2109797	hsa-miR-4475	CLIP-seq
MIRT2627426	hsa-miR-4484	CLIP-seq
MIRT2433318	hsa-miR-4517	CLIP-seq
MIRT2627427	hsa-miR-4534	CLIP-seq
MIRT2627428	hsa-miR-4644	CLIP-seq
MIRT2627429	hsa-miR-4647	CLIP-seq
MIRT2333215	hsa-miR-466	CLIP-seq
MIRT2627430	hsa-miR-4662b	CLIP-seq
MIRT2333217	hsa-miR-4672	CLIP-seq
MIRT2627431	hsa-miR-4678	CLIP-seq
MIRT1369905	hsa-miR-4696	CLIP-seq
MIRT2627433	hsa-miR-4729	CLIP-seq
MIRT2627437	hsa-miR-4795-3p	CLIP-seq
MIRT2627438	hsa-miR-4797-5p	CLIP-seq
MIRT1369915	hsa-miR-4799-5p	CLIP-seq
MIRT1369918	hsa-miR-513b	CLIP-seq
MIRT2627441	hsa-miR-514	CLIP-seq
MIRT2627442	hsa-miR-514b-3p	CLIP-seq
MIRT1369919	hsa-miR-519d	CLIP-seq
MIRT1369920	hsa-miR-520a-3p	CLIP-seq
MIRT1369921	hsa-miR-520b	CLIP-seq
MIRT1369922	hsa-miR-520c-3p	CLIP-seq
MIRT1369923	hsa-miR-520d-3p	CLIP-seq
MIRT1369924	hsa-miR-520e	CLIP-seq
MIRT2627443	hsa-miR-539	CLIP-seq
MIRT2627444	hsa-miR-548an	CLIP-seq
MIRT1369928	hsa-miR-548v	CLIP-seq
MIRT1369930	hsa-miR-561	CLIP-seq
MIRT2109805	hsa-miR-563	CLIP-seq
MIRT2627445	hsa-miR-576-5p	CLIP-seq
MIRT1369932	hsa-miR-583	CLIP-seq
MIRT2333224	hsa-miR-603	CLIP-seq
MIRT1369936	hsa-miR-607	CLIP-seq
MIRT1369937	hsa-miR-624	CLIP-seq
MIRT2333226	hsa-miR-634	CLIP-seq
MIRT1369943	hsa-miR-93	CLIP-seq
MIRT1369944	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	18239682
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	25882817, 26094769
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	18287541, 26094769
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030334	Process	Regulation of cell migration	IBA
GO:0030334	Process	Regulation of cell migration	IEA
GO:0030334	Process	Regulation of cell migration	IMP	26818812
GO:0030334	Process	Regulation of cell migration	ISS
GO:0031122	Process	Cytoplasmic microtubule organization	IMP	18287541
GO:0031252	Component	Cell leading edge	IEA
GO:0031252	Component	Cell leading edge	ISS
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0042802	Function	Identical protein binding	IPI	18239682
GO:0042803	Function	Protein homodimerization activity	IDA	18239682, 22203681
GO:0042981	Process	Regulation of apoptotic process	IBA
GO:0042981	Process	Regulation of apoptotic process	IDA	22203681
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0046777	Process	Protein autophosphorylation	IDA	18239682
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	26094769
GO:0051893	Process	Regulation of focal adhesion assembly	IDA	23128389
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708
GO:0106310	Function	Protein serine kinase activity	IEA

Other IDs

• MIM: 616563
• HGNC: 11088
• e!Ensembl: ENSG00000065613

Protein

• UniProt ID: Q9H2G2
• Protein name: STE20-like serine/threonine-protein kinase (STE20-like kinase) (hSLK) (EC 2.7.11.1) (CTCL tumor antigen se20-9) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (Serine/threonine-protein kinase 2)
• Protein function: Mediates apoptosis and actin stress fiber dissolution.
• PDB: 2J51, 2JFL, 2JFM, 2UV2, 4USF, 6HVD, 8BEM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	34 → 292	Protein kinase domain	Domain
  PF12474	PKK	852 → 990	Polo kinase kinase	Family
  PF12474	PKK	1020 → 1160	Polo kinase kinase	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle. {ECO:0000269|PubMed:10699464}.
• Sequence:

  MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLA
  AAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVM
  LELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKN
  TRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNP
  MRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPI
  RELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACIL
  ESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIK
  ENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQM
  FENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKD
  VISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEV
  PIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADT
  DQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSG
  ENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSI
  SLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKE
  EQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRL
  RDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQE
  QEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKH
  QLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAK
  TRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEA
  NVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQ
  EVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS

• Sequence length: 1235

Pathways

KEGG:

Oocyte meiosis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BASAL CELL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BENIGN PROSTATIC HYPERPLASIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BILIARY TRACT CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CERVICAL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEAR CELL RENAL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CUTANEOUS MELANOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETIC RETINOPATHY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIFFERENTIATED THYROID CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESTROGEN-RECEPTOR NEGATIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GASTRIC CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEPATOCELLULAR CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KIDNEY CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE MYELOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROBLASTOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-HODGKINS LYMPHOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN ENDOMETRIOID CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN SEROUS CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
THYROID CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
THYROID CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TOXIC NODULAR GOITER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	19525980		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon Carcinoma	Colon Carcinoma	BEFREE	28370249		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	29534578		★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	30328087		★☆☆☆☆ Found in Text Mining only
Kaposi Sarcoma	Kaposi Sarcoma	BEFREE	11280784, 8618237, 9622096		★☆☆☆☆ Found in Text Mining only
Kidney Failure, Acute	Kidney Failure	BEFREE	29187370		★☆☆☆☆ Found in Text Mining only
Leiomyoma	Leiomyoma	Pubtator	35689443	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	28204826	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Glioma	Glioma	BEFREE	29534578		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	19525980		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	19525980, 23154402		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	28370249		★☆☆☆☆ Found in Text Mining only
Myopathy	Myopathy	BEFREE	28153048		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11280784, 29187370		★☆☆☆☆ Found in Text Mining only
Ovarian Serous Adenocarcinoma	Ovarian serous adenocarcinoma	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	32859632	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	11280784		★★☆☆☆ Found in Text Mining + Unknown/Other Associations