Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	9703
Gene name	Bridge-like lipid transfer protein family member 2
Gene symbol	BLTP2
Synonyms (NCBI Gene)	BCOXBCOX1CT101FMP27HobKIAA0100
Chromosome	17
Chromosome location	17q11.2

196

Show/Hide all (196)

miRTarBase ID	miRNA	Experiments	Reference
MIRT030428	hsa-miR-24-3p	Microarray	19748357
MIRT051551	hsa-let-7e-5p	CLASH	23622248
MIRT050726	hsa-miR-18a-5p	CLASH	23622248
MIRT050492	hsa-miR-20a-5p	CLASH	23622248
MIRT049189	hsa-miR-92a-3p	CLASH	23622248
MIRT047690	hsa-miR-10a-5p	CLASH	23622248
MIRT047690	hsa-miR-10a-5p	CLASH	23622248
MIRT047481	hsa-miR-10b-5p	CLASH	23622248
MIRT047337	hsa-miR-181a-5p	CLASH	23622248
MIRT044853	hsa-miR-320a	CLASH	23622248
MIRT040869	hsa-miR-18a-3p	CLASH	23622248
MIRT040108	hsa-miR-615-3p	CLASH	23622248
MIRT040108	hsa-miR-615-3p	CLASH	23622248
MIRT039443	hsa-miR-421	CLASH	23622248
MIRT1085550	hsa-miR-217	CLIP-seq
MIRT1085551	hsa-miR-3150a-3p	CLIP-seq
MIRT1085552	hsa-miR-3163	CLIP-seq
MIRT1085553	hsa-miR-3175	CLIP-seq
MIRT1085554	hsa-miR-323b-3p	CLIP-seq
MIRT1085555	hsa-miR-3591-3p	CLIP-seq
MIRT1085556	hsa-miR-383	CLIP-seq
MIRT1085557	hsa-miR-4282	CLIP-seq
MIRT1085558	hsa-miR-4418	CLIP-seq
MIRT1085559	hsa-miR-4436a	CLIP-seq
MIRT1085560	hsa-miR-4463	CLIP-seq
MIRT1085561	hsa-miR-4667-5p	CLIP-seq
MIRT1085562	hsa-miR-4700-5p	CLIP-seq
MIRT1085563	hsa-miR-4728-5p	CLIP-seq
MIRT1085564	hsa-miR-4759	CLIP-seq
MIRT1085565	hsa-miR-4772-5p	CLIP-seq
MIRT1085566	hsa-miR-4796-5p	CLIP-seq
MIRT1085567	hsa-miR-486-5p	CLIP-seq
MIRT1085568	hsa-miR-508-5p	CLIP-seq
MIRT1085569	hsa-miR-509-3-5p	CLIP-seq
MIRT1085570	hsa-miR-509-5p	CLIP-seq
MIRT1085571	hsa-miR-548c-3p	CLIP-seq
MIRT1085572	hsa-miR-563	CLIP-seq
MIRT1085573	hsa-miR-654-3p	CLIP-seq
MIRT1085574	hsa-miR-875-5p	CLIP-seq
MIRT1085575	hsa-miR-939	CLIP-seq
MIRT2021963	hsa-miR-1184	CLIP-seq
MIRT2021964	hsa-miR-1224-3p	CLIP-seq
MIRT2021965	hsa-miR-1260	CLIP-seq
MIRT2021966	hsa-miR-1260b	CLIP-seq
MIRT2021967	hsa-miR-1261	CLIP-seq
MIRT2021968	hsa-miR-1280	CLIP-seq
MIRT2021969	hsa-miR-2114	CLIP-seq
MIRT1085550	hsa-miR-217	CLIP-seq
MIRT2021970	hsa-miR-3125	CLIP-seq
MIRT1085551	hsa-miR-3150a-3p	CLIP-seq
MIRT2021971	hsa-miR-3162-3p	CLIP-seq
MIRT1085552	hsa-miR-3163	CLIP-seq
MIRT1085553	hsa-miR-3175	CLIP-seq
MIRT2021972	hsa-miR-3202	CLIP-seq
MIRT1085554	hsa-miR-323b-3p	CLIP-seq
MIRT1085555	hsa-miR-3591-3p	CLIP-seq
MIRT2021973	hsa-miR-3614-5p	CLIP-seq
MIRT1085556	hsa-miR-383	CLIP-seq
MIRT2021974	hsa-miR-3916	CLIP-seq
MIRT2021975	hsa-miR-3925-3p	CLIP-seq
MIRT2021976	hsa-miR-4254	CLIP-seq
MIRT2021977	hsa-miR-4271	CLIP-seq
MIRT2021978	hsa-miR-4286	CLIP-seq
MIRT2021979	hsa-miR-4292	CLIP-seq
MIRT2021980	hsa-miR-4293	CLIP-seq
MIRT2021981	hsa-miR-4308	CLIP-seq
MIRT2021982	hsa-miR-4310	CLIP-seq
MIRT1085558	hsa-miR-4418	CLIP-seq
MIRT1085559	hsa-miR-4436a	CLIP-seq
MIRT1085560	hsa-miR-4463	CLIP-seq
MIRT2021983	hsa-miR-4476	CLIP-seq
MIRT2021984	hsa-miR-4533	CLIP-seq
MIRT2021985	hsa-miR-4659a-5p	CLIP-seq
MIRT2021986	hsa-miR-4659b-5p	CLIP-seq
MIRT1085561	hsa-miR-4667-5p	CLIP-seq
MIRT2021987	hsa-miR-4681	CLIP-seq
MIRT2021988	hsa-miR-4685-5p	CLIP-seq
MIRT2021989	hsa-miR-4691-3p	CLIP-seq
MIRT2021990	hsa-miR-4693-5p	CLIP-seq
MIRT1085562	hsa-miR-4700-5p	CLIP-seq
MIRT2021991	hsa-miR-4719	CLIP-seq
MIRT2021992	hsa-miR-4725-3p	CLIP-seq
MIRT1085563	hsa-miR-4728-5p	CLIP-seq
MIRT2021993	hsa-miR-4747-5p	CLIP-seq
MIRT2021994	hsa-miR-4749-3p	CLIP-seq
MIRT1085564	hsa-miR-4759	CLIP-seq
MIRT1085565	hsa-miR-4772-5p	CLIP-seq
MIRT2021995	hsa-miR-4776-3p	CLIP-seq
MIRT1085566	hsa-miR-4796-5p	CLIP-seq
MIRT1085567	hsa-miR-486-5p	CLIP-seq
MIRT1085568	hsa-miR-508-5p	CLIP-seq
MIRT1085569	hsa-miR-509-3-5p	CLIP-seq
MIRT1085570	hsa-miR-509-5p	CLIP-seq
MIRT2021996	hsa-miR-512-5p	CLIP-seq
MIRT2021997	hsa-miR-515-5p	CLIP-seq
MIRT2021998	hsa-miR-532-3p	CLIP-seq
MIRT1085572	hsa-miR-563	CLIP-seq
MIRT2021999	hsa-miR-607	CLIP-seq
MIRT1085573	hsa-miR-654-3p	CLIP-seq
MIRT2022000	hsa-miR-671-5p	CLIP-seq
MIRT2022001	hsa-miR-766	CLIP-seq
MIRT1085574	hsa-miR-875-5p	CLIP-seq
MIRT2022002	hsa-miR-935	CLIP-seq
MIRT1085575	hsa-miR-939	CLIP-seq
MIRT2021963	hsa-miR-1184	CLIP-seq
MIRT2253458	hsa-miR-1185	CLIP-seq
MIRT2021964	hsa-miR-1224-3p	CLIP-seq
MIRT2021965	hsa-miR-1260	CLIP-seq
MIRT2021966	hsa-miR-1260b	CLIP-seq
MIRT2021967	hsa-miR-1261	CLIP-seq
MIRT2021968	hsa-miR-1280	CLIP-seq
MIRT2253459	hsa-miR-1343	CLIP-seq
MIRT2253460	hsa-miR-149	CLIP-seq
MIRT2021969	hsa-miR-2114	CLIP-seq
MIRT2253461	hsa-miR-3074-5p	CLIP-seq
MIRT2021970	hsa-miR-3125	CLIP-seq
MIRT2253462	hsa-miR-3144-5p	CLIP-seq
MIRT1085551	hsa-miR-3150a-3p	CLIP-seq
MIRT1085553	hsa-miR-3175	CLIP-seq
MIRT2253463	hsa-miR-3194-5p	CLIP-seq
MIRT2021972	hsa-miR-3202	CLIP-seq
MIRT2253464	hsa-miR-3660	CLIP-seq
MIRT1085556	hsa-miR-383	CLIP-seq
MIRT2021974	hsa-miR-3916	CLIP-seq
MIRT2021975	hsa-miR-3925-3p	CLIP-seq
MIRT2253465	hsa-miR-3943	CLIP-seq
MIRT2021976	hsa-miR-4254	CLIP-seq
MIRT2021977	hsa-miR-4271	CLIP-seq
MIRT2021979	hsa-miR-4292	CLIP-seq
MIRT2021980	hsa-miR-4293	CLIP-seq
MIRT2021981	hsa-miR-4308	CLIP-seq
MIRT2253466	hsa-miR-4313	CLIP-seq
MIRT2253467	hsa-miR-4435	CLIP-seq
MIRT1085559	hsa-miR-4436a	CLIP-seq
MIRT2253468	hsa-miR-4437	CLIP-seq
MIRT1085560	hsa-miR-4463	CLIP-seq
MIRT2021983	hsa-miR-4476	CLIP-seq
MIRT2253469	hsa-miR-4526	CLIP-seq
MIRT2021984	hsa-miR-4533	CLIP-seq
MIRT2021985	hsa-miR-4659a-5p	CLIP-seq
MIRT2021986	hsa-miR-4659b-5p	CLIP-seq
MIRT1085561	hsa-miR-4667-5p	CLIP-seq
MIRT2253470	hsa-miR-4674	CLIP-seq
MIRT2021987	hsa-miR-4681	CLIP-seq
MIRT2021988	hsa-miR-4685-5p	CLIP-seq
MIRT1085562	hsa-miR-4700-5p	CLIP-seq
MIRT2021991	hsa-miR-4719	CLIP-seq
MIRT2021992	hsa-miR-4725-3p	CLIP-seq
MIRT1085563	hsa-miR-4728-5p	CLIP-seq
MIRT2021993	hsa-miR-4747-5p	CLIP-seq
MIRT2021994	hsa-miR-4749-3p	CLIP-seq
MIRT1085564	hsa-miR-4759	CLIP-seq
MIRT1085565	hsa-miR-4772-5p	CLIP-seq
MIRT2021995	hsa-miR-4776-3p	CLIP-seq
MIRT2021997	hsa-miR-515-5p	CLIP-seq
MIRT2021998	hsa-miR-532-3p	CLIP-seq
MIRT1085572	hsa-miR-563	CLIP-seq
MIRT2022000	hsa-miR-671-5p	CLIP-seq
MIRT2253471	hsa-miR-711	CLIP-seq
MIRT2253472	hsa-miR-760	CLIP-seq
MIRT2022001	hsa-miR-766	CLIP-seq
MIRT2022002	hsa-miR-935	CLIP-seq
MIRT1085575	hsa-miR-939	CLIP-seq
MIRT2465529	hsa-miR-150	CLIP-seq
MIRT2465530	hsa-miR-4769-3p	CLIP-seq
MIRT2021964	hsa-miR-1224-3p	CLIP-seq
MIRT2021965	hsa-miR-1260	CLIP-seq
MIRT2021966	hsa-miR-1260b	CLIP-seq
MIRT2021967	hsa-miR-1261	CLIP-seq
MIRT2021968	hsa-miR-1280	CLIP-seq
MIRT2021969	hsa-miR-2114	CLIP-seq
MIRT2021976	hsa-miR-4254	CLIP-seq
MIRT2021979	hsa-miR-4292	CLIP-seq
MIRT2021980	hsa-miR-4293	CLIP-seq
MIRT2021981	hsa-miR-4308	CLIP-seq
MIRT2021987	hsa-miR-4681	CLIP-seq
MIRT2021991	hsa-miR-4719	CLIP-seq
MIRT2021994	hsa-miR-4749-3p	CLIP-seq
MIRT1085567	hsa-miR-486-5p	CLIP-seq
MIRT2021998	hsa-miR-532-3p	CLIP-seq
MIRT2022000	hsa-miR-671-5p	CLIP-seq
MIRT2021964	hsa-miR-1224-3p	CLIP-seq
MIRT2021965	hsa-miR-1260	CLIP-seq
MIRT2021966	hsa-miR-1260b	CLIP-seq
MIRT2021967	hsa-miR-1261	CLIP-seq
MIRT2021968	hsa-miR-1280	CLIP-seq
MIRT2021969	hsa-miR-2114	CLIP-seq
MIRT2021976	hsa-miR-4254	CLIP-seq
MIRT2021979	hsa-miR-4292	CLIP-seq
MIRT2021980	hsa-miR-4293	CLIP-seq
MIRT2021981	hsa-miR-4308	CLIP-seq
MIRT2021987	hsa-miR-4681	CLIP-seq
MIRT2021991	hsa-miR-4719	CLIP-seq
MIRT2021994	hsa-miR-4749-3p	CLIP-seq
MIRT2021998	hsa-miR-532-3p	CLIP-seq
MIRT2022000	hsa-miR-671-5p	CLIP-seq

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence
GO:0005739	Component	Mitochondrion	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0031966	Component	Mitochondrial membrane	IEA
GO:0035091	Function	Phosphatidylinositol binding	ISS
GO:0140268	Component	Endoplasmic reticulum-plasma membrane contact site	ISS

MIM	HGNC	e!Ensembl
610664	28960	ENSG00000007202

Q14667

Protein name

Bridge-like lipid transfer protein family member 2 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein) (Protein hobbit homolog)

Protein function

Tube-forming lipid transport protein which binds to phosphatidylinositols and affects phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10344	Fmp27	26 → 476	Mitochondrial protein from FMP27	Family
PF10344	Fmp27	445 → 674	Mitochondrial protein from FMP27	Family
PF10347	Fmp27_GFWDK	1028 → 1160	RNA pol II promoter Fmp27 protein domain	Domain
PF10351	Apt1	1703 → 2176	Golgi-body localisation protein domain	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in pancreas, placenta and up-regulated in breast carcinoma epithelial cells, ductal in situ carcinoma (DCIS), invasive breast carcinoma (IBC) and metastatic breast carcinoma cells (MET). {ECO:0000269|PubMed:16289875}.

Sequence

MPLFFSALLVLLLVALSALFLGRWLVVRLATKWCQRKLQAELKIGSFRFFWIQNVSLKFQ
QHQQTVEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSDLSAPFSQSAGVDQKEL
SFSPSLLKIFCQLFSIHVDAINIMVLKVDTSESLWHIQISRSRFLLDSDGKRLICEVSLC
KINSKVLKSGQLEDTCLVELSLALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQSQL
LCQGPSLASKPVPCSEVTENLVEPTLPGLFLLQQLPDQVKVKMENTSVVLSMNSQKRHLT
WTLKLLQFLYHRDEDQLPLRSFTANSDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKASV
QVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPVLKQRKKRTFPQILAPII
FSTSISNVNISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHI
QRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQ
CLSRILSLMGPQSGKSAVSRHSSFGESVSLLWKVDLKVEDMNLFTLSALVGASEVRLDTL
TILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEV
QCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAP
EPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGN
SIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLDE
AVGVQKWLKGLHQGTRAWASPSPVPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDE
SKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMR
RALLTWSLAGLELVALADASFHGPEHVVEQVQELDPGSPFPPEGLDLVIQWCRMLKCNVK
SFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPL
KFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDW
HMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGDLDINVRTASKYDDCC
FLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIK
MDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYK
QLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVT
QMVSDLSQVTVHLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDG
DPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAK
KPKRGVPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQL
CGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLK
QKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGG
MVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVLENQEKE
DLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQ
LEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQL
QLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRL
TEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQ
SGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEV
GDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSPEHPVD
DIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDF
AMAVKRDSRKALVAQVIKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSV
GDKNPGKKSIFGRRK

Sequence length

2235

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (10)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Carcinoma	Breast Carcinoma	BEFREE	16289875, 24489812		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	37145128	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Carcinoma	Ductal Carcinoma	BEFREE	24489812		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glaucoma Open Angle	Open angle glaucoma	Pubtator	29847670	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Breast Carcinoma	Breast Cancer	BEFREE	16289875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	16289875, 24489812		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	26338045		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29867023		★★★★★ ★☆☆☆☆ Found in Text Mining only
Noninfiltrating Intraductal Carcinoma	Ductal carcinoma	BEFREE	16289875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	26338045		★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	24489812		★★★★★ ★☆☆☆☆ Found in Text Mining only

BLTP2 (bridge-like lipid transfer protein family member 2)