Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	9698
Gene name	Pumilio RNA binding family member 1
Gene symbol	PUM1
Synonyms (NCBI Gene)	HSPUMNEDMSFPUMHPUMH1PUML1SCA47
Chromosome	1
Chromosome location	1p35.2
Summary	This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA bindin

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SNP ID	Visualize variation	Clinical significance	Consequence
rs771145682	T>A,C	Likely-pathogenic	Missense variant, coding sequence variant
rs1557539450	G>A	Likely-pathogenic	Coding sequence variant, missense variant

451

Show/Hide all (451)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016684	hsa-miR-423-3p	Sequencing	20371350
MIRT019509	hsa-miR-151a-3p	Sequencing	20371350
MIRT025121	hsa-miR-181a-5p	Sequencing	20371350
MIRT031662	hsa-miR-16-5p	Proteomics	18668040
MIRT032335	hsa-let-7b-5p	Proteomics	18668040
MIRT032335	hsa-let-7b-5p	CLASH	23622248
MIRT048648	hsa-miR-99a-5p	CLASH	23622248
MIRT045010	hsa-miR-186-5p	CLASH	23622248
MIRT043018	hsa-miR-324-5p	CLASH	23622248
MIRT042968	hsa-miR-324-3p	CLASH	23622248
MIRT038400	hsa-miR-296-3p	CLASH	23622248
MIRT506025	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521559	hsa-miR-4528	HITS-CLIP	21572407
MIRT506026	hsa-miR-340-5p	HITS-CLIP	21572407
MIRT506024	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT506023	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT506026	hsa-miR-340-5p	HITS-CLIP	23313552
MIRT506024	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT506023	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT700482	hsa-miR-548e-5p	HITS-CLIP	23313552
MIRT700481	hsa-miR-4704-5p	HITS-CLIP	23313552
MIRT700480	hsa-miR-451b	HITS-CLIP	23313552
MIRT506025	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT700479	hsa-miR-571	HITS-CLIP	23313552
MIRT700478	hsa-miR-4696	HITS-CLIP	23313552
MIRT700477	hsa-miR-3618	HITS-CLIP	23313552
MIRT068001	hsa-miR-568	HITS-CLIP	23313552
MIRT700476	hsa-miR-5004-3p	HITS-CLIP	23313552
MIRT700475	hsa-miR-3149	HITS-CLIP	23313552
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	20371350
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	20371350
MIRT512621	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	20371350
MIRT543671	hsa-miR-3920	PAR-CLIP	20371350
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT068025	hsa-miR-508-3p	PAR-CLIP	20371350
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	20371350
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	20371350
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	20371350
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	20371350
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	20371350
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	20371350
MIRT543669	hsa-miR-760	PAR-CLIP	20371350
MIRT543668	hsa-miR-4283	PAR-CLIP	20371350
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	20371350
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	20371350
MIRT512621	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	20371350
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	20371350
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	20371350
MIRT506025	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT521559	hsa-miR-4528	PAR-CLIP	21572407
MIRT506024	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT521558	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT506023	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	21572407
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	21572407
MIRT512621	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	21572407
MIRT543671	hsa-miR-3920	PAR-CLIP	21572407
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	21572407
MIRT068025	hsa-miR-508-3p	PAR-CLIP	21572407
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	21572407
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	21572407
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	21572407
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	21572407
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	21572407
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	21572407
MIRT543669	hsa-miR-760	PAR-CLIP	21572407
MIRT543668	hsa-miR-4283	PAR-CLIP	21572407
MIRT521559	hsa-miR-4528	PAR-CLIP	23446348
MIRT506026	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT506024	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521558	hsa-miR-335-3p	PAR-CLIP	23446348
MIRT506023	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	23446348
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	23446348
MIRT512621	hsa-miR-651-3p	PAR-CLIP	23446348
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	23446348
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	23446348
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	23446348
MIRT506025	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT506026	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT506024	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT506023	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT439855	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT439855	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT506026	hsa-miR-340-5p	qRT-PCRLuciferase reporter assayWestern blot	25151966
MIRT506026	hsa-miR-340-5p	qRT-PCRLuciferase reporter assayWestern blot	25151966
MIRT506026	hsa-miR-340-5p	qRT-PCRLuciferase reporter assayWestern blot	25151966
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	26701625
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	26701625
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	26701625
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	26701625
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	26701625
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	26701625
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	26701625
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	26701625
MIRT543671	hsa-miR-3920	PAR-CLIP	26701625
MIRT543671	hsa-miR-3920	PAR-CLIP	26701625
MIRT543671	hsa-miR-3920	PAR-CLIP	26701625
MIRT543671	hsa-miR-3920	PAR-CLIP	26701625
MIRT543668	hsa-miR-4283	PAR-CLIP	26701625
MIRT543668	hsa-miR-4283	PAR-CLIP	26701625
MIRT543668	hsa-miR-4283	PAR-CLIP	26701625
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	26701625
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	26701625
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	26701625
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	26701625
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	26701625
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	26701625
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	26701625
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	26701625
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	26701625
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	26701625
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	26701625
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	26701625
MIRT068025	hsa-miR-508-3p	PAR-CLIP	26701625
MIRT068025	hsa-miR-508-3p	PAR-CLIP	26701625
MIRT068025	hsa-miR-508-3p	PAR-CLIP	26701625
MIRT068025	hsa-miR-508-3p	PAR-CLIP	26701625
MIRT512621	hsa-miR-651-3p	PAR-CLIP	26701625
MIRT512621	hsa-miR-651-3p	PAR-CLIP	26701625
MIRT512621	hsa-miR-651-3p	PAR-CLIP	26701625
MIRT512621	hsa-miR-651-3p	PAR-CLIP	26701625
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	26701625
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	26701625
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	26701625
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	26701625
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	26701625
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	26701625
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	26701625
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	26701625
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	26701625
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	26701625
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	26701625
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	26701625
MIRT543669	hsa-miR-760	PAR-CLIP	26701625
MIRT543669	hsa-miR-760	PAR-CLIP	26701625
MIRT543669	hsa-miR-760	PAR-CLIP	26701625
MIRT543669	hsa-miR-760	PAR-CLIP	26701625
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	26701625
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	26701625
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	26701625
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	26701625
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	26701625
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	26701625
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	26701625
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	26701625
MIRT506025	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521559	hsa-miR-4528	HITS-CLIP	21572407
MIRT506026	hsa-miR-340-5p	HITS-CLIP	21572407
MIRT506024	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT506023	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT506026	hsa-miR-340-5p	HITS-CLIP	23313552
MIRT506024	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT506023	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT700482	hsa-miR-548e-5p	HITS-CLIP	23313552
MIRT700481	hsa-miR-4704-5p	HITS-CLIP	23313552
MIRT700480	hsa-miR-451b	HITS-CLIP	23313552
MIRT506025	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT700479	hsa-miR-571	HITS-CLIP	23313552
MIRT700478	hsa-miR-4696	HITS-CLIP	23313552
MIRT700477	hsa-miR-3618	HITS-CLIP	23313552
MIRT068001	hsa-miR-568	HITS-CLIP	23313552
MIRT700476	hsa-miR-5004-3p	HITS-CLIP	23313552
MIRT700475	hsa-miR-3149	HITS-CLIP	23313552
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	20371350
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	20371350
MIRT512621	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	20371350
MIRT543671	hsa-miR-3920	PAR-CLIP	20371350
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	20371350
MIRT068025	hsa-miR-508-3p	PAR-CLIP	20371350
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	20371350
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	20371350
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	20371350
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	20371350
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	20371350
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	20371350
MIRT543669	hsa-miR-760	PAR-CLIP	20371350
MIRT543668	hsa-miR-4283	PAR-CLIP	20371350
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	20371350
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	20371350
MIRT512621	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	20371350
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	20371350
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	20371350
MIRT506025	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT521559	hsa-miR-4528	PAR-CLIP	21572407
MIRT506024	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT521558	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT506023	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	21572407
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	21572407
MIRT512621	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	21572407
MIRT543671	hsa-miR-3920	PAR-CLIP	21572407
MIRT543670	hsa-miR-29a-5p	PAR-CLIP	21572407
MIRT068025	hsa-miR-508-3p	PAR-CLIP	21572407
MIRT249004	hsa-miR-219a-5p	PAR-CLIP	21572407
MIRT249013	hsa-miR-4782-3p	PAR-CLIP	21572407
MIRT249015	hsa-miR-6766-3p	PAR-CLIP	21572407
MIRT249009	hsa-miR-4445-5p	PAR-CLIP	21572407
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	21572407
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	21572407
MIRT543669	hsa-miR-760	PAR-CLIP	21572407
MIRT543668	hsa-miR-4283	PAR-CLIP	21572407
MIRT521559	hsa-miR-4528	PAR-CLIP	23446348
MIRT506026	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT506024	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521558	hsa-miR-335-3p	PAR-CLIP	23446348
MIRT506023	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT512623	hsa-miR-99a-3p	PAR-CLIP	23446348
MIRT512622	hsa-miR-99b-3p	PAR-CLIP	23446348
MIRT512621	hsa-miR-651-3p	PAR-CLIP	23446348
MIRT512619	hsa-miR-7112-5p	PAR-CLIP	23446348
MIRT512620	hsa-miR-4708-3p	PAR-CLIP	23446348
MIRT512618	hsa-miR-6809-5p	PAR-CLIP	23446348
MIRT506025	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT506026	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT506024	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT506023	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT1276879	hsa-miR-129-5p	CLIP-seq
MIRT1276880	hsa-miR-1303	CLIP-seq
MIRT1276881	hsa-miR-144	CLIP-seq
MIRT1276882	hsa-miR-181a	CLIP-seq
MIRT1276883	hsa-miR-181b	CLIP-seq
MIRT1276884	hsa-miR-181c	CLIP-seq
MIRT1276885	hsa-miR-181d	CLIP-seq
MIRT1276886	hsa-miR-214	CLIP-seq
MIRT1276887	hsa-miR-300	CLIP-seq
MIRT1276888	hsa-miR-3146	CLIP-seq
MIRT1276889	hsa-miR-338-5p	CLIP-seq
MIRT1276890	hsa-miR-3613-3p	CLIP-seq
MIRT1276891	hsa-miR-3619-5p	CLIP-seq
MIRT1276892	hsa-miR-3647-3p	CLIP-seq
MIRT1276893	hsa-miR-381	CLIP-seq
MIRT1276894	hsa-miR-4262	CLIP-seq
MIRT1276895	hsa-miR-4275	CLIP-seq
MIRT1276896	hsa-miR-4645-3p	CLIP-seq
MIRT1276897	hsa-miR-4666-3p	CLIP-seq
MIRT1276898	hsa-miR-4731-3p	CLIP-seq
MIRT1276899	hsa-miR-4801	CLIP-seq
MIRT1276900	hsa-miR-518a-5p	CLIP-seq
MIRT1276901	hsa-miR-520d-5p	CLIP-seq
MIRT1276902	hsa-miR-524-5p	CLIP-seq
MIRT1276903	hsa-miR-527	CLIP-seq
MIRT1276904	hsa-miR-567	CLIP-seq
MIRT1276905	hsa-miR-761	CLIP-seq
MIRT1276906	hsa-miR-1228	CLIP-seq
MIRT1276907	hsa-miR-127-5p	CLIP-seq
MIRT1276879	hsa-miR-129-5p	CLIP-seq
MIRT1276908	hsa-miR-203	CLIP-seq
MIRT1276909	hsa-miR-2053	CLIP-seq
MIRT1276910	hsa-miR-2682	CLIP-seq
MIRT1276887	hsa-miR-300	CLIP-seq
MIRT1276911	hsa-miR-30a	CLIP-seq
MIRT1276912	hsa-miR-30b	CLIP-seq
MIRT1276913	hsa-miR-30c	CLIP-seq
MIRT1276914	hsa-miR-30d	CLIP-seq
MIRT1276915	hsa-miR-30e	CLIP-seq
MIRT1276888	hsa-miR-3146	CLIP-seq
MIRT1276916	hsa-miR-3182	CLIP-seq
MIRT1276917	hsa-miR-3202	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT1276889	hsa-miR-338-5p	CLIP-seq
MIRT1276919	hsa-miR-3682-5p	CLIP-seq
MIRT1276920	hsa-miR-3686	CLIP-seq
MIRT1276921	hsa-miR-371b-5p	CLIP-seq
MIRT1276922	hsa-miR-377	CLIP-seq
MIRT1276893	hsa-miR-381	CLIP-seq
MIRT1276923	hsa-miR-449c	CLIP-seq
MIRT1276897	hsa-miR-4666-3p	CLIP-seq
MIRT1276924	hsa-miR-4668-3p	CLIP-seq
MIRT1276925	hsa-miR-4705	CLIP-seq
MIRT1276926	hsa-miR-4712-5p	CLIP-seq
MIRT1276927	hsa-miR-4719	CLIP-seq
MIRT1276928	hsa-miR-4747-5p	CLIP-seq
MIRT1276929	hsa-miR-4761-5p	CLIP-seq
MIRT1276930	hsa-miR-5095	CLIP-seq
MIRT1276931	hsa-miR-515-5p	CLIP-seq
MIRT1276932	hsa-miR-548ac	CLIP-seq
MIRT1276933	hsa-miR-548c-3p	CLIP-seq
MIRT1276934	hsa-miR-548d-3p	CLIP-seq
MIRT1276935	hsa-miR-548l	CLIP-seq
MIRT1276936	hsa-miR-548n	CLIP-seq
MIRT1276937	hsa-miR-548z	CLIP-seq
MIRT1276938	hsa-miR-552	CLIP-seq
MIRT1276939	hsa-miR-563	CLIP-seq
MIRT1276904	hsa-miR-567	CLIP-seq
MIRT1276940	hsa-miR-569	CLIP-seq
MIRT1276941	hsa-miR-582-5p	CLIP-seq
MIRT1276942	hsa-miR-624	CLIP-seq
MIRT1276943	hsa-miR-633	CLIP-seq
MIRT1276944	hsa-miR-770-5p	CLIP-seq
MIRT1276945	hsa-miR-940	CLIP-seq
MIRT1276887	hsa-miR-300	CLIP-seq
MIRT1276893	hsa-miR-381	CLIP-seq
MIRT1276897	hsa-miR-4666-3p	CLIP-seq
MIRT2081490	hsa-miR-299-3p	CLIP-seq
MIRT2081491	hsa-miR-3136-5p	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT2081492	hsa-miR-409-5p	CLIP-seq
MIRT2081493	hsa-miR-4439	CLIP-seq
MIRT2081494	hsa-miR-4491	CLIP-seq
MIRT2081495	hsa-miR-450b-5p	CLIP-seq
MIRT2081496	hsa-miR-4657	CLIP-seq
MIRT2081497	hsa-miR-4709-5p	CLIP-seq
MIRT1276927	hsa-miR-4719	CLIP-seq
MIRT2081498	hsa-miR-4757-5p	CLIP-seq
MIRT2081499	hsa-miR-507	CLIP-seq
MIRT2081500	hsa-miR-557	CLIP-seq
MIRT1276904	hsa-miR-567	CLIP-seq
MIRT2081501	hsa-miR-663b	CLIP-seq
MIRT2081502	hsa-miR-943	CLIP-seq
MIRT1276906	hsa-miR-1228	CLIP-seq
MIRT2307452	hsa-miR-1284	CLIP-seq
MIRT2307453	hsa-miR-1290	CLIP-seq
MIRT2307454	hsa-miR-1294	CLIP-seq
MIRT2307455	hsa-miR-1323	CLIP-seq
MIRT1276881	hsa-miR-144	CLIP-seq
MIRT1276882	hsa-miR-181a	CLIP-seq
MIRT1276883	hsa-miR-181b	CLIP-seq
MIRT1276884	hsa-miR-181c	CLIP-seq
MIRT1276885	hsa-miR-181d	CLIP-seq
MIRT1276908	hsa-miR-203	CLIP-seq
MIRT1276886	hsa-miR-214	CLIP-seq
MIRT2307456	hsa-miR-219-5p	CLIP-seq
MIRT1276910	hsa-miR-2682	CLIP-seq
MIRT2081490	hsa-miR-299-3p	CLIP-seq
MIRT1276887	hsa-miR-300	CLIP-seq
MIRT1276911	hsa-miR-30a	CLIP-seq
MIRT1276912	hsa-miR-30b	CLIP-seq
MIRT1276913	hsa-miR-30c	CLIP-seq
MIRT1276914	hsa-miR-30d	CLIP-seq
MIRT1276915	hsa-miR-30e	CLIP-seq
MIRT2307457	hsa-miR-3126-5p	CLIP-seq
MIRT1276888	hsa-miR-3146	CLIP-seq
MIRT2307458	hsa-miR-3167	CLIP-seq
MIRT1276916	hsa-miR-3182	CLIP-seq
MIRT2307459	hsa-miR-3184	CLIP-seq
MIRT1276917	hsa-miR-3202	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT2307460	hsa-miR-337-3p	CLIP-seq
MIRT1276889	hsa-miR-338-5p	CLIP-seq
MIRT1276891	hsa-miR-3619-5p	CLIP-seq
MIRT1276892	hsa-miR-3647-3p	CLIP-seq
MIRT1276919	hsa-miR-3682-5p	CLIP-seq
MIRT1276920	hsa-miR-3686	CLIP-seq
MIRT1276921	hsa-miR-371b-5p	CLIP-seq
MIRT1276922	hsa-miR-377	CLIP-seq
MIRT1276893	hsa-miR-381	CLIP-seq
MIRT2307461	hsa-miR-411	CLIP-seq
MIRT2307462	hsa-miR-423-5p	CLIP-seq
MIRT1276894	hsa-miR-4262	CLIP-seq
MIRT2307463	hsa-miR-4272	CLIP-seq
MIRT1276895	hsa-miR-4275	CLIP-seq
MIRT2307464	hsa-miR-4314	CLIP-seq
MIRT2307465	hsa-miR-4419a	CLIP-seq
MIRT2307466	hsa-miR-4445	CLIP-seq
MIRT2081494	hsa-miR-4491	CLIP-seq
MIRT1276923	hsa-miR-449c	CLIP-seq
MIRT2307467	hsa-miR-4510	CLIP-seq
MIRT2307468	hsa-miR-4640-5p	CLIP-seq
MIRT1276896	hsa-miR-4645-3p	CLIP-seq
MIRT2081496	hsa-miR-4657	CLIP-seq
MIRT1276897	hsa-miR-4666-3p	CLIP-seq
MIRT1276924	hsa-miR-4668-3p	CLIP-seq
MIRT2307469	hsa-miR-4699-3p	CLIP-seq
MIRT1276925	hsa-miR-4705	CLIP-seq
MIRT2081497	hsa-miR-4709-5p	CLIP-seq
MIRT1276926	hsa-miR-4712-5p	CLIP-seq
MIRT2307470	hsa-miR-4726-5p	CLIP-seq
MIRT1276928	hsa-miR-4747-5p	CLIP-seq
MIRT2081498	hsa-miR-4757-5p	CLIP-seq
MIRT1276929	hsa-miR-4761-5p	CLIP-seq
MIRT2307471	hsa-miR-4781-3p	CLIP-seq
MIRT2307472	hsa-miR-4789-5p	CLIP-seq
MIRT1276930	hsa-miR-5095	CLIP-seq
MIRT1276931	hsa-miR-515-5p	CLIP-seq
MIRT1276933	hsa-miR-548c-3p	CLIP-seq
MIRT2307473	hsa-miR-548o	CLIP-seq
MIRT1276938	hsa-miR-552	CLIP-seq
MIRT1276939	hsa-miR-563	CLIP-seq
MIRT1276904	hsa-miR-567	CLIP-seq
MIRT1276941	hsa-miR-582-5p	CLIP-seq
MIRT1276942	hsa-miR-624	CLIP-seq
MIRT2081501	hsa-miR-663b	CLIP-seq
MIRT1276905	hsa-miR-761	CLIP-seq
MIRT1276944	hsa-miR-770-5p	CLIP-seq
MIRT2307474	hsa-miR-876-5p	CLIP-seq
MIRT1276945	hsa-miR-940	CLIP-seq
MIRT1276909	hsa-miR-2053	CLIP-seq
MIRT1276887	hsa-miR-300	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT1276893	hsa-miR-381	CLIP-seq
MIRT1276897	hsa-miR-4666-3p	CLIP-seq
MIRT1276900	hsa-miR-518a-5p	CLIP-seq
MIRT1276903	hsa-miR-527	CLIP-seq
MIRT1276904	hsa-miR-567	CLIP-seq
MIRT1276890	hsa-miR-3613-3p	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT2457480	hsa-miR-4279	CLIP-seq
MIRT2307455	hsa-miR-1323	CLIP-seq
MIRT2604996	hsa-miR-146a	CLIP-seq
MIRT2604997	hsa-miR-146b-5p	CLIP-seq
MIRT2604998	hsa-miR-186	CLIP-seq
MIRT2307456	hsa-miR-219-5p	CLIP-seq
MIRT2604999	hsa-miR-28-3p	CLIP-seq
MIRT2605000	hsa-miR-3143	CLIP-seq
MIRT2605001	hsa-miR-3159	CLIP-seq
MIRT2605002	hsa-miR-3174	CLIP-seq
MIRT2307459	hsa-miR-3184	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT2605003	hsa-miR-3672	CLIP-seq
MIRT2307462	hsa-miR-423-5p	CLIP-seq
MIRT2307466	hsa-miR-4445	CLIP-seq
MIRT2605004	hsa-miR-4635	CLIP-seq
MIRT1276927	hsa-miR-4719	CLIP-seq
MIRT1276929	hsa-miR-4761-5p	CLIP-seq
MIRT2605005	hsa-miR-543	CLIP-seq
MIRT2605006	hsa-miR-548aa	CLIP-seq
MIRT2307473	hsa-miR-548o	CLIP-seq
MIRT2605007	hsa-miR-589	CLIP-seq
MIRT1276942	hsa-miR-624	CLIP-seq
MIRT2605008	hsa-miR-651	CLIP-seq
MIRT2605009	hsa-miR-720	CLIP-seq
MIRT2605010	hsa-miR-921	CLIP-seq
MIRT2307455	hsa-miR-1323	CLIP-seq
MIRT2604996	hsa-miR-146a	CLIP-seq
MIRT2604997	hsa-miR-146b-5p	CLIP-seq
MIRT2604998	hsa-miR-186	CLIP-seq
MIRT2307456	hsa-miR-219-5p	CLIP-seq
MIRT2605000	hsa-miR-3143	CLIP-seq
MIRT2605001	hsa-miR-3159	CLIP-seq
MIRT2605002	hsa-miR-3174	CLIP-seq
MIRT2307459	hsa-miR-3184	CLIP-seq
MIRT1276918	hsa-miR-323-3p	CLIP-seq
MIRT2307462	hsa-miR-423-5p	CLIP-seq
MIRT2307466	hsa-miR-4445	CLIP-seq
MIRT2605004	hsa-miR-4635	CLIP-seq
MIRT1276927	hsa-miR-4719	CLIP-seq
MIRT1276929	hsa-miR-4761-5p	CLIP-seq
MIRT2605005	hsa-miR-543	CLIP-seq
MIRT2605006	hsa-miR-548aa	CLIP-seq
MIRT2307473	hsa-miR-548o	CLIP-seq
MIRT2605007	hsa-miR-589	CLIP-seq
MIRT1276942	hsa-miR-624	CLIP-seq
MIRT2605008	hsa-miR-651	CLIP-seq
MIRT2605010	hsa-miR-921	CLIP-seq

Show/Hide all (50)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IDA	20818387
GO:0000932	Component	P-body	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IDA	26724866
GO:0003723	Function	RNA binding	IEA
GO:0003730	Function	MRNA 3'-UTR binding	IBA
GO:0003730	Function	MRNA 3'-UTR binding	IDA	18776931, 20818387, 21572425, 25768905
GO:0003730	Function	MRNA 3'-UTR binding	IEA
GO:0003730	Function	MRNA 3'-UTR binding	TAS	31048766
GO:0005515	Function	Protein binding	IPI	23125361, 25340845, 32814053, 36931259
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006417	Process	Regulation of translation	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0007283	Process	Spermatogenesis	ISS
GO:0008344	Process	Adult locomotory behavior	IEA
GO:0008344	Process	Adult locomotory behavior	ISS
GO:0010494	Component	Cytoplasmic stress granule	IDA	25340845
GO:0010494	Component	Cytoplasmic stress granule	IEA
GO:0010608	Process	Post-transcriptional regulation of gene expression	IDA	25100735
GO:0010608	Process	Post-transcriptional regulation of gene expression	IEA
GO:0010608	Process	Post-transcriptional regulation of gene expression	IMP	28431233
GO:0016441	Process	Post-transcriptional gene silencing	IEA
GO:0016441	Process	Post-transcriptional gene silencing	ISS
GO:0030154	Process	Cell differentiation	IEA
GO:0030424	Component	Axon	IEA
GO:0035196	Process	MiRNA processing	IBA
GO:0035196	Process	MiRNA processing	IMP	28431233
GO:0035198	Function	MiRNA binding	IDA	28431233
GO:0035198	Function	MiRNA binding	IEA
GO:0043488	Process	Regulation of mRNA stability	IBA
GO:0043488	Process	Regulation of mRNA stability	IDA	26724866
GO:0048863	Process	Stem cell differentiation	IEA
GO:0048863	Process	Stem cell differentiation	ISS
GO:0051726	Process	Regulation of cell cycle	IDA	20818387
GO:0051983	Process	Regulation of chromosome segregation	IDA	26724866
GO:0051983	Process	Regulation of chromosome segregation	IEA
GO:0060964	Process	Regulation of miRNA-mediated gene silencing	TAS	18776931
GO:0061157	Process	MRNA destabilization	IEA
GO:0061157	Process	MRNA destabilization	ISS
GO:0061158	Process	3'-UTR-mediated mRNA destabilization	IEA
GO:0061158	Process	3'-UTR-mediated mRNA destabilization	TAS	31048766
GO:1900246	Process	Positive regulation of RIG-I signaling pathway	IDA	25340845
GO:1900246	Process	Positive regulation of RIG-I signaling pathway	IEA
GO:2000637	Process	Positive regulation of miRNA-mediated gene silencing	IDA	20818387, 22345517
GO:2000637	Process	Positive regulation of miRNA-mediated gene silencing	IEA

MIM	HGNC	e!Ensembl
607204	14957	ENSG00000134644

Q14671

Protein name

Pumilio homolog 1 (HsPUM) (Pumilio-1)

Protein function

Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Respo

PDB

1IB2 , 1M8W , 1M8X , 1M8Y , 1M8Z , 2YJY , 3BSB , 3BSX , 3Q0L , 3Q0M , 3Q0N , 3Q0O , 3Q0P , 5YKH , 5YKI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00806	PUF	852 → 886	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	889 → 921	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	924 → 957	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	960 → 992	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	996 → 1030	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	1032 → 1066	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	1068 → 1102	Pumilio-family RNA binding repeat	Repeat
PF00806	PUF	1112 → 1145	Pumilio-family RNA binding repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain, heart, kidney, muscle, intestine and stomach. Not expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested. {ECO:0000269|PubMed:124

Sequence

MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGT
HSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEH
QVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTS
DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGGF
GPRDADSDENDKGEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPG
NCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQF
DYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIGLA
PAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAAA
AAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFG
QGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAA
AAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSSL
FSQGSAQPANTSLGFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRT
SSSLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNG
SGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNR
YPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGNY
VIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQNEMVRELDGH
VLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPD
QTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASN
VVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIV
MHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII

Sequence length

1186

Interactions

View interactions

	KEGG		Reactome
	Spinocerebellar ataxia		Golgi Associated Vesicle Biogenesis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Neurodevelopmental delay	Likely pathogenic	rs2124510562	RCV002274366	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
PUM1-associated developmental disability-ataxia-seizure syndrome	Likely pathogenic; Pathogenic	rs1557539450, rs1557541619	RCV003768266 RCV005409732	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
PUM1-related disorder	Likely pathogenic	rs2521564145	RCV003479643	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Spastic ataxia	Likely pathogenic	rs2124008235	RCV001647256	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Spinocerebellar ataxia 47	Pathogenic; Likely pathogenic	rs1639458746, rs2124008285, rs1557539450, rs1557541619, rs1640658015, rs1644321851	RCV001333770 RCV002272738 RCV000755727 RCV000755741 RCV001193938 RCV001265597 View all (1 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (23)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Cervical cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Global developmental delay	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hereditary breast ovarian cancer syndrome	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intellectual disability	Uncertain significance; Conflicting classifications of pathogenicity	ClinVar Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Late-onset spinocerebellar ataxia	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodevelopmental disorder	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDER WITH MOTOR ABNORMALITIES, AND FACIAL DYSMORPHISM	—	HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDER WITH MOTOR ABNORMALITIES, SEIZURES, AND FACIAL DYSMORPHISM	—	GenCC, HPO GenCC, HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Seizure	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TREATMENT-RESISTANT HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (45)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	31395860		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ataxia, Spinocerebellar	Spinocerebellar Ataxia	BEFREE	31422002		★★★★★ ★☆☆☆☆ Found in Text Mining only
Blepharoptosis	Ptosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	18042273, 18211679, 27526934, 33522650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Byzanthine arch palate	High palate	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	32316190	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	29428722, 31751911		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholestasis of pregnancy	Cholestasis of pregnancy	BEFREE	27871465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Clinodactyly	Clinodactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Clinodactyly of fingers	Clinodactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Clumsiness - motor delay	Motor delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	30755640	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptorchidism	Cryptorchidism	GENOMICS_ENGLAND_DG	31859446		★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Development Disorder	BEFREE	29474920, 30903679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dwarfism	Dwarfism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysarthria	Dysarthria	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	32439920	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	GENOMICS_ENGLAND_DG	31859446		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Infertility	Infertility	Pubtator	29297114	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Breast Carcinoma	Breast Cancer	BEFREE	18211679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	GENOMICS_ENGLAND_DG	31859446		★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Intellectual Disability	Mental retardation	HPO_DG			★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	29428722, 31751911		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	15287981		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30197756		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	30229827, 31395860		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	29145611		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	29145611	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	BEFREE	29145611		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	29145611	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Failure, Premature	Ovarian Failure	BEFREE	29297114		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	29428722, 31751911		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	30833663	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Premature Menopause	Premature Menopause	BEFREE	29297114		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	33985534	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	Pubtator	35371093	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ptosis	Ptosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
SPINOCEREBELLAR ATAXIA 47	Spinocerebellar Ataxia	UNIPROT_DG	29474920		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
SPINOCEREBELLAR ATAXIA 47	Spinocerebellar Ataxia	CLINVAR_DG	29474920		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
SPINOCEREBELLAR ATAXIA 47	Spinocerebellar Ataxia	GENOMICS_ENGLAND_DG			★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Spinocerebellar Ataxia Type 1	Spinocerebellar Ataxia	BEFREE	25768905		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	37469018	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Subfertility	Subfertility	BEFREE	29297114		★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	18211679	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	36161300	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

PUM1 (pumilio RNA binding family member 1)