Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	9693
Gene name	Rap guanine nucleotide exchange factor 2
Gene symbol	RAPGEF2
Synonyms (NCBI Gene)	CNrasGEFNRAPGEPPDZ-GEF1PDZGEF1RA-GEFRA-GEF-1RAGEFRap-GEPnRap GEP
Chromosome	4
Chromosome location	4q32.1
Summary	Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017869	hsa-miR-335-5p	Microarray	18185580
MIRT020791	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT023803	hsa-miR-1-3p	Microarray	18668037
MIRT045434	hsa-miR-149-5p	CLASH	23622248
MIRT039795	hsa-miR-615-3p	CLASH	23622248
MIRT093335	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT093336	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT093344	hsa-miR-5002-5p	PAR-CLIP	20371350
MIRT093342	hsa-miR-3620-3p	PAR-CLIP	20371350
MIRT093337	hsa-miR-339-5p	PAR-CLIP	20371350
MIRT093345	hsa-miR-6748-3p	PAR-CLIP	20371350
MIRT093334	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT561673	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT093340	hsa-miR-659-3p	PAR-CLIP	20371350
MIRT561672	hsa-miR-335-3p	PAR-CLIP	20371350
MIRT561671	hsa-miR-4720-5p	PAR-CLIP	20371350
MIRT212035	hsa-miR-8066	PAR-CLIP	20371350
MIRT570130	hsa-miR-7152-3p	PAR-CLIP	20371350
MIRT093335	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT093336	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT093344	hsa-miR-5002-5p	PAR-CLIP	20371350
MIRT093342	hsa-miR-3620-3p	PAR-CLIP	20371350
MIRT093337	hsa-miR-339-5p	PAR-CLIP	20371350
MIRT093345	hsa-miR-6748-3p	PAR-CLIP	20371350
MIRT093334	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT561673	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT093340	hsa-miR-659-3p	PAR-CLIP	20371350
MIRT561672	hsa-miR-335-3p	PAR-CLIP	20371350
MIRT561671	hsa-miR-4720-5p	PAR-CLIP	20371350
MIRT164476	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT164477	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT093335	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT093336	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT093344	hsa-miR-5002-5p	PAR-CLIP	20371350
MIRT093342	hsa-miR-3620-3p	PAR-CLIP	20371350
MIRT093337	hsa-miR-339-5p	PAR-CLIP	20371350
MIRT093345	hsa-miR-6748-3p	PAR-CLIP	20371350
MIRT093334	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT561673	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT093340	hsa-miR-659-3p	PAR-CLIP	20371350
MIRT561672	hsa-miR-335-3p	PAR-CLIP	20371350
MIRT561671	hsa-miR-4720-5p	PAR-CLIP	20371350
MIRT212035	hsa-miR-8066	PAR-CLIP	20371350
MIRT570130	hsa-miR-7152-3p	PAR-CLIP	20371350
MIRT093335	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT093336	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT093344	hsa-miR-5002-5p	PAR-CLIP	20371350
MIRT093342	hsa-miR-3620-3p	PAR-CLIP	20371350
MIRT093337	hsa-miR-339-5p	PAR-CLIP	20371350
MIRT093345	hsa-miR-6748-3p	PAR-CLIP	20371350
MIRT093334	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT561673	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT093340	hsa-miR-659-3p	PAR-CLIP	20371350
MIRT561672	hsa-miR-335-3p	PAR-CLIP	20371350
MIRT561671	hsa-miR-4720-5p	PAR-CLIP	20371350
MIRT1290638	hsa-miR-103b	CLIP-seq
MIRT1290639	hsa-miR-1180	CLIP-seq
MIRT1290640	hsa-miR-1197	CLIP-seq
MIRT1290641	hsa-miR-1203	CLIP-seq
MIRT1290642	hsa-miR-1243	CLIP-seq
MIRT1290643	hsa-miR-1245b-5p	CLIP-seq
MIRT1290644	hsa-miR-1253	CLIP-seq
MIRT1290645	hsa-miR-1256	CLIP-seq
MIRT1290646	hsa-miR-1295	CLIP-seq
MIRT1290647	hsa-miR-1324	CLIP-seq
MIRT1290648	hsa-miR-1470	CLIP-seq
MIRT1290649	hsa-miR-155	CLIP-seq
MIRT1290650	hsa-miR-15a	CLIP-seq
MIRT1290651	hsa-miR-15b	CLIP-seq
MIRT1290652	hsa-miR-16	CLIP-seq
MIRT1290653	hsa-miR-1911	CLIP-seq
MIRT1290654	hsa-miR-195	CLIP-seq
MIRT1290655	hsa-miR-19a	CLIP-seq
MIRT1290656	hsa-miR-19b	CLIP-seq
MIRT1290657	hsa-miR-203	CLIP-seq
MIRT1290658	hsa-miR-2113	CLIP-seq
MIRT1290659	hsa-miR-2115	CLIP-seq
MIRT1290660	hsa-miR-221	CLIP-seq
MIRT1290661	hsa-miR-222	CLIP-seq
MIRT1290662	hsa-miR-23a	CLIP-seq
MIRT1290663	hsa-miR-23b	CLIP-seq
MIRT1290664	hsa-miR-23c	CLIP-seq
MIRT1290665	hsa-miR-24	CLIP-seq
MIRT1290666	hsa-miR-296-3p	CLIP-seq
MIRT1290667	hsa-miR-302a	CLIP-seq
MIRT1290668	hsa-miR-302b	CLIP-seq
MIRT1290669	hsa-miR-302c	CLIP-seq
MIRT1290670	hsa-miR-302d	CLIP-seq
MIRT1290671	hsa-miR-302e	CLIP-seq
MIRT1290672	hsa-miR-30a	CLIP-seq
MIRT1290673	hsa-miR-30b	CLIP-seq
MIRT1290674	hsa-miR-30c	CLIP-seq
MIRT1290675	hsa-miR-30d	CLIP-seq
MIRT1290676	hsa-miR-30e	CLIP-seq
MIRT1290677	hsa-miR-3117-3p	CLIP-seq
MIRT1290678	hsa-miR-3120-5p	CLIP-seq
MIRT1290679	hsa-miR-3121-3p	CLIP-seq
MIRT1290680	hsa-miR-3124-5p	CLIP-seq
MIRT1290681	hsa-miR-3138	CLIP-seq
MIRT1290682	hsa-miR-3142	CLIP-seq
MIRT1290683	hsa-miR-3143	CLIP-seq
MIRT1290684	hsa-miR-3169	CLIP-seq
MIRT1290685	hsa-miR-3180-5p	CLIP-seq
MIRT1290686	hsa-miR-3187-3p	CLIP-seq
MIRT1290687	hsa-miR-3194-3p	CLIP-seq
MIRT1290688	hsa-miR-331-3p	CLIP-seq
MIRT1290689	hsa-miR-3529	CLIP-seq
MIRT1290690	hsa-miR-3614-3p	CLIP-seq
MIRT1290691	hsa-miR-3664-3p	CLIP-seq
MIRT1290692	hsa-miR-369-3p	CLIP-seq
MIRT1290693	hsa-miR-372	CLIP-seq
MIRT1290694	hsa-miR-373	CLIP-seq
MIRT1290695	hsa-miR-374a	CLIP-seq
MIRT1290696	hsa-miR-374b	CLIP-seq
MIRT1290697	hsa-miR-379	CLIP-seq
MIRT1290698	hsa-miR-3944-5p	CLIP-seq
MIRT1290699	hsa-miR-410	CLIP-seq
MIRT1290700	hsa-miR-424	CLIP-seq
MIRT1290701	hsa-miR-425	CLIP-seq
MIRT1290702	hsa-miR-4275	CLIP-seq
MIRT1290703	hsa-miR-4294	CLIP-seq
MIRT1290704	hsa-miR-431	CLIP-seq
MIRT1290705	hsa-miR-4328	CLIP-seq
MIRT1290706	hsa-miR-4330	CLIP-seq
MIRT1290707	hsa-miR-4436a	CLIP-seq
MIRT1290708	hsa-miR-4436b-3p	CLIP-seq
MIRT1290709	hsa-miR-4451	CLIP-seq
MIRT1290710	hsa-miR-4457	CLIP-seq
MIRT1290711	hsa-miR-4461	CLIP-seq
MIRT1290712	hsa-miR-4468	CLIP-seq
MIRT1290713	hsa-miR-4515	CLIP-seq
MIRT1290714	hsa-miR-4524	CLIP-seq
MIRT1290715	hsa-miR-4528	CLIP-seq
MIRT1290716	hsa-miR-4529-5p	CLIP-seq
MIRT1290717	hsa-miR-4536	CLIP-seq
MIRT1290718	hsa-miR-4650-3p	CLIP-seq
MIRT1290719	hsa-miR-4652-3p	CLIP-seq
MIRT1290720	hsa-miR-4664-3p	CLIP-seq
MIRT1290721	hsa-miR-4667-3p	CLIP-seq
MIRT1290722	hsa-miR-4677-3p	CLIP-seq
MIRT1290723	hsa-miR-4700-3p	CLIP-seq
MIRT1290724	hsa-miR-4704-3p	CLIP-seq
MIRT1290725	hsa-miR-4722-3p	CLIP-seq
MIRT1290726	hsa-miR-4731-3p	CLIP-seq
MIRT1290727	hsa-miR-4732-5p	CLIP-seq
MIRT1290728	hsa-miR-4733-5p	CLIP-seq
MIRT1290729	hsa-miR-4747-5p	CLIP-seq
MIRT1290730	hsa-miR-4759	CLIP-seq
MIRT1290731	hsa-miR-4761-3p	CLIP-seq
MIRT1290732	hsa-miR-4786-3p	CLIP-seq
MIRT1290733	hsa-miR-4786-5p	CLIP-seq
MIRT1290734	hsa-miR-4801	CLIP-seq
MIRT1290735	hsa-miR-485-3p	CLIP-seq
MIRT1290736	hsa-miR-497	CLIP-seq
MIRT1290737	hsa-miR-501-3p	CLIP-seq
MIRT1290738	hsa-miR-502-3p	CLIP-seq
MIRT1290739	hsa-miR-503	CLIP-seq
MIRT1290740	hsa-miR-510	CLIP-seq
MIRT1290741	hsa-miR-511	CLIP-seq
MIRT1290742	hsa-miR-512-5p	CLIP-seq
MIRT1290743	hsa-miR-516a-3p	CLIP-seq
MIRT1290744	hsa-miR-519a	CLIP-seq
MIRT1290745	hsa-miR-519b-3p	CLIP-seq
MIRT1290746	hsa-miR-519c-3p	CLIP-seq
MIRT1290747	hsa-miR-520a-3p	CLIP-seq
MIRT1290748	hsa-miR-520a-5p	CLIP-seq
MIRT1290749	hsa-miR-520b	CLIP-seq
MIRT1290750	hsa-miR-520c-3p	CLIP-seq
MIRT1290751	hsa-miR-520d-3p	CLIP-seq
MIRT1290752	hsa-miR-520e	CLIP-seq
MIRT1290753	hsa-miR-525-5p	CLIP-seq
MIRT1290754	hsa-miR-543	CLIP-seq
MIRT1290755	hsa-miR-548v	CLIP-seq
MIRT1290756	hsa-miR-577	CLIP-seq
MIRT1290757	hsa-miR-580	CLIP-seq
MIRT1290758	hsa-miR-633	CLIP-seq
MIRT1290759	hsa-miR-642a	CLIP-seq
MIRT1290760	hsa-miR-646	CLIP-seq
MIRT1290761	hsa-miR-665	CLIP-seq
MIRT1290762	hsa-miR-671-5p	CLIP-seq
MIRT1290763	hsa-miR-759	CLIP-seq
MIRT1290764	hsa-miR-769-5p	CLIP-seq
MIRT1290765	hsa-miR-885-3p	CLIP-seq
MIRT1290766	hsa-miR-891b	CLIP-seq
MIRT1290639	hsa-miR-1180	CLIP-seq
MIRT1290641	hsa-miR-1203	CLIP-seq
MIRT1290642	hsa-miR-1243	CLIP-seq
MIRT1290643	hsa-miR-1245b-5p	CLIP-seq
MIRT1290646	hsa-miR-1295	CLIP-seq
MIRT1290655	hsa-miR-19a	CLIP-seq
MIRT1290656	hsa-miR-19b	CLIP-seq
MIRT2086472	hsa-miR-2110	CLIP-seq
MIRT1290660	hsa-miR-221	CLIP-seq
MIRT1290661	hsa-miR-222	CLIP-seq
MIRT1290679	hsa-miR-3121-3p	CLIP-seq
MIRT1290682	hsa-miR-3142	CLIP-seq
MIRT1290685	hsa-miR-3180-5p	CLIP-seq
MIRT1290690	hsa-miR-3614-3p	CLIP-seq
MIRT2086473	hsa-miR-3614-5p	CLIP-seq
MIRT2086474	hsa-miR-3668	CLIP-seq
MIRT2086475	hsa-miR-3689d	CLIP-seq
MIRT2086476	hsa-miR-383	CLIP-seq
MIRT1290699	hsa-miR-410	CLIP-seq
MIRT2086477	hsa-miR-4267	CLIP-seq
MIRT2086478	hsa-miR-4271	CLIP-seq
MIRT2086479	hsa-miR-4289	CLIP-seq
MIRT2086480	hsa-miR-432	CLIP-seq
MIRT1290707	hsa-miR-4436a	CLIP-seq
MIRT2086481	hsa-miR-4443	CLIP-seq
MIRT1290712	hsa-miR-4468	CLIP-seq
MIRT2086482	hsa-miR-4474-5p	CLIP-seq
MIRT2086483	hsa-miR-4533	CLIP-seq
MIRT1290720	hsa-miR-4664-3p	CLIP-seq
MIRT2086484	hsa-miR-4667-5p	CLIP-seq
MIRT2086485	hsa-miR-4684-5p	CLIP-seq
MIRT2086486	hsa-miR-4700-5p	CLIP-seq
MIRT2086487	hsa-miR-4725-3p	CLIP-seq
MIRT1290729	hsa-miR-4747-5p	CLIP-seq
MIRT2086488	hsa-miR-4764-5p	CLIP-seq
MIRT2086489	hsa-miR-4772-5p	CLIP-seq
MIRT2086490	hsa-miR-4778-3p	CLIP-seq
MIRT2086491	hsa-miR-502-5p	CLIP-seq
MIRT1290741	hsa-miR-511	CLIP-seq
MIRT1290755	hsa-miR-548v	CLIP-seq
MIRT2086492	hsa-miR-890	CLIP-seq
MIRT2086493	hsa-miR-9	CLIP-seq
MIRT2086494	hsa-miR-942	CLIP-seq
MIRT2311498	hsa-miR-10a	CLIP-seq
MIRT2311499	hsa-miR-10b	CLIP-seq
MIRT2311500	hsa-miR-1183	CLIP-seq
MIRT1290640	hsa-miR-1197	CLIP-seq
MIRT1290641	hsa-miR-1203	CLIP-seq
MIRT2311501	hsa-miR-1207-5p	CLIP-seq
MIRT2311502	hsa-miR-1244	CLIP-seq
MIRT2311503	hsa-miR-1247	CLIP-seq
MIRT1290644	hsa-miR-1253	CLIP-seq
MIRT1290645	hsa-miR-1256	CLIP-seq
MIRT2311504	hsa-miR-1286	CLIP-seq
MIRT1290647	hsa-miR-1324	CLIP-seq
MIRT2311505	hsa-miR-145	CLIP-seq
MIRT1290648	hsa-miR-1470	CLIP-seq
MIRT1290650	hsa-miR-15a	CLIP-seq
MIRT1290651	hsa-miR-15b	CLIP-seq
MIRT1290652	hsa-miR-16	CLIP-seq
MIRT1290653	hsa-miR-1911	CLIP-seq
MIRT1290654	hsa-miR-195	CLIP-seq
MIRT1290655	hsa-miR-19a	CLIP-seq
MIRT1290656	hsa-miR-19b	CLIP-seq
MIRT2311506	hsa-miR-200b	CLIP-seq
MIRT2311507	hsa-miR-200c	CLIP-seq
MIRT1290662	hsa-miR-23a	CLIP-seq
MIRT1290663	hsa-miR-23b	CLIP-seq
MIRT1290664	hsa-miR-23c	CLIP-seq
MIRT1290665	hsa-miR-24	CLIP-seq
MIRT1290666	hsa-miR-296-3p	CLIP-seq
MIRT1290679	hsa-miR-3121-3p	CLIP-seq
MIRT1290680	hsa-miR-3124-5p	CLIP-seq
MIRT1290683	hsa-miR-3143	CLIP-seq
MIRT2311508	hsa-miR-3154	CLIP-seq
MIRT2311509	hsa-miR-3160-5p	CLIP-seq
MIRT2311510	hsa-miR-3170	CLIP-seq
MIRT2311511	hsa-miR-3173-3p	CLIP-seq
MIRT2311512	hsa-miR-3175	CLIP-seq
MIRT2311513	hsa-miR-3179	CLIP-seq
MIRT2311514	hsa-miR-3185	CLIP-seq
MIRT1290686	hsa-miR-3187-3p	CLIP-seq
MIRT2311515	hsa-miR-3189-3p	CLIP-seq
MIRT1290688	hsa-miR-331-3p	CLIP-seq
MIRT2311516	hsa-miR-3620	CLIP-seq
MIRT2311517	hsa-miR-3650	CLIP-seq
MIRT2311518	hsa-miR-3656	CLIP-seq
MIRT2311519	hsa-miR-3673	CLIP-seq
MIRT2311520	hsa-miR-3688-5p	CLIP-seq
MIRT1290692	hsa-miR-369-3p	CLIP-seq
MIRT2311521	hsa-miR-3913-3p	CLIP-seq
MIRT1290700	hsa-miR-424	CLIP-seq
MIRT1290701	hsa-miR-425	CLIP-seq
MIRT2086479	hsa-miR-4289	CLIP-seq
MIRT2311522	hsa-miR-429	CLIP-seq
MIRT1290703	hsa-miR-4294	CLIP-seq
MIRT2311523	hsa-miR-4318	CLIP-seq
MIRT2311524	hsa-miR-4326	CLIP-seq
MIRT1290705	hsa-miR-4328	CLIP-seq
MIRT1290706	hsa-miR-4330	CLIP-seq
MIRT2311525	hsa-miR-4420	CLIP-seq
MIRT2311526	hsa-miR-4434	CLIP-seq
MIRT1290707	hsa-miR-4436a	CLIP-seq
MIRT1290710	hsa-miR-4457	CLIP-seq
MIRT1290712	hsa-miR-4468	CLIP-seq
MIRT2311527	hsa-miR-4484	CLIP-seq
MIRT2311528	hsa-miR-4514	CLIP-seq
MIRT2311529	hsa-miR-4516	CLIP-seq
MIRT1290714	hsa-miR-4524	CLIP-seq
MIRT1290715	hsa-miR-4528	CLIP-seq
MIRT1290716	hsa-miR-4529-5p	CLIP-seq
MIRT2311530	hsa-miR-4530	CLIP-seq
MIRT2311531	hsa-miR-4659a-5p	CLIP-seq
MIRT2311532	hsa-miR-4659b-5p	CLIP-seq
MIRT1290721	hsa-miR-4667-3p	CLIP-seq
MIRT1290722	hsa-miR-4677-3p	CLIP-seq
MIRT2311533	hsa-miR-4692	CLIP-seq
MIRT2311534	hsa-miR-4693-5p	CLIP-seq
MIRT2311535	hsa-miR-4694-3p	CLIP-seq
MIRT2311536	hsa-miR-4699-5p	CLIP-seq
MIRT1290723	hsa-miR-4700-3p	CLIP-seq
MIRT2311537	hsa-miR-4701-5p	CLIP-seq
MIRT1290724	hsa-miR-4704-3p	CLIP-seq
MIRT1290725	hsa-miR-4722-3p	CLIP-seq
MIRT1290726	hsa-miR-4731-3p	CLIP-seq
MIRT1290728	hsa-miR-4733-5p	CLIP-seq
MIRT2311538	hsa-miR-4736	CLIP-seq
MIRT1290729	hsa-miR-4747-5p	CLIP-seq
MIRT2311539	hsa-miR-4763-3p	CLIP-seq
MIRT2311540	hsa-miR-4776-3p	CLIP-seq
MIRT2086490	hsa-miR-4778-3p	CLIP-seq
MIRT1290732	hsa-miR-4786-3p	CLIP-seq
MIRT1290733	hsa-miR-4786-5p	CLIP-seq
MIRT2311541	hsa-miR-4793-3p	CLIP-seq
MIRT1290734	hsa-miR-4801	CLIP-seq
MIRT2311542	hsa-miR-489	CLIP-seq
MIRT1290736	hsa-miR-497	CLIP-seq
MIRT2311543	hsa-miR-499-3p	CLIP-seq
MIRT2311544	hsa-miR-499a-3p	CLIP-seq
MIRT2086491	hsa-miR-502-5p	CLIP-seq
MIRT1290739	hsa-miR-503	CLIP-seq
MIRT1290740	hsa-miR-510	CLIP-seq
MIRT1290741	hsa-miR-511	CLIP-seq
MIRT1290742	hsa-miR-512-5p	CLIP-seq
MIRT2311545	hsa-miR-513b	CLIP-seq
MIRT2311546	hsa-miR-522	CLIP-seq
MIRT2311547	hsa-miR-541	CLIP-seq
MIRT1290754	hsa-miR-543	CLIP-seq
MIRT2311548	hsa-miR-548an	CLIP-seq
MIRT2311549	hsa-miR-588	CLIP-seq
MIRT1290758	hsa-miR-633	CLIP-seq
MIRT2311550	hsa-miR-634	CLIP-seq
MIRT1290759	hsa-miR-642a	CLIP-seq
MIRT2311551	hsa-miR-642b	CLIP-seq
MIRT2311552	hsa-miR-644	CLIP-seq
MIRT1290760	hsa-miR-646	CLIP-seq
MIRT2311553	hsa-miR-654-5p	CLIP-seq
MIRT2311554	hsa-miR-659	CLIP-seq
MIRT2311555	hsa-miR-663b	CLIP-seq
MIRT1290762	hsa-miR-671-5p	CLIP-seq
MIRT1290764	hsa-miR-769-5p	CLIP-seq
MIRT2311556	hsa-miR-892a	CLIP-seq
MIRT2393488	hsa-miR-1	CLIP-seq
MIRT1290650	hsa-miR-15a	CLIP-seq
MIRT1290651	hsa-miR-15b	CLIP-seq
MIRT1290652	hsa-miR-16	CLIP-seq
MIRT1290654	hsa-miR-195	CLIP-seq
MIRT2393489	hsa-miR-206	CLIP-seq
MIRT1290662	hsa-miR-23a	CLIP-seq
MIRT1290663	hsa-miR-23b	CLIP-seq
MIRT1290664	hsa-miR-23c	CLIP-seq
MIRT1290666	hsa-miR-296-3p	CLIP-seq
MIRT2311519	hsa-miR-3673	CLIP-seq
MIRT1290700	hsa-miR-424	CLIP-seq
MIRT1290712	hsa-miR-4468	CLIP-seq
MIRT1290714	hsa-miR-4524	CLIP-seq
MIRT1290715	hsa-miR-4528	CLIP-seq
MIRT1290722	hsa-miR-4677-3p	CLIP-seq
MIRT1290736	hsa-miR-497	CLIP-seq
MIRT1290739	hsa-miR-503	CLIP-seq
MIRT2393490	hsa-miR-613	CLIP-seq
MIRT1290758	hsa-miR-633	CLIP-seq
MIRT1290760	hsa-miR-646	CLIP-seq
MIRT2432442	hsa-miR-3065-5p	CLIP-seq
MIRT1290640	hsa-miR-1197	CLIP-seq
MIRT1290647	hsa-miR-1324	CLIP-seq
MIRT1290665	hsa-miR-24	CLIP-seq
MIRT1290707	hsa-miR-4436a	CLIP-seq
MIRT1290710	hsa-miR-4457	CLIP-seq
MIRT1290723	hsa-miR-4700-3p	CLIP-seq
MIRT1290725	hsa-miR-4722-3p	CLIP-seq
MIRT1290726	hsa-miR-4731-3p	CLIP-seq
MIRT1290734	hsa-miR-4801	CLIP-seq
MIRT1290644	hsa-miR-1253	CLIP-seq
MIRT2457749	hsa-miR-3153	CLIP-seq
MIRT2311508	hsa-miR-3154	CLIP-seq
MIRT2311512	hsa-miR-3175	CLIP-seq
MIRT2311513	hsa-miR-3179	CLIP-seq
MIRT2311514	hsa-miR-3185	CLIP-seq
MIRT2311526	hsa-miR-4434	CLIP-seq
MIRT2311529	hsa-miR-4516	CLIP-seq
MIRT1290638	hsa-miR-103b	CLIP-seq
MIRT1290640	hsa-miR-1197	CLIP-seq
MIRT2607956	hsa-miR-1207-3p	CLIP-seq
MIRT2607957	hsa-miR-127-5p	CLIP-seq
MIRT2607958	hsa-miR-1283	CLIP-seq
MIRT1290647	hsa-miR-1324	CLIP-seq
MIRT2607959	hsa-miR-141	CLIP-seq
MIRT1290649	hsa-miR-155	CLIP-seq
MIRT2607960	hsa-miR-1910	CLIP-seq
MIRT1290655	hsa-miR-19a	CLIP-seq
MIRT1290656	hsa-miR-19b	CLIP-seq
MIRT2607961	hsa-miR-200a	CLIP-seq
MIRT1290658	hsa-miR-2113	CLIP-seq
MIRT1290665	hsa-miR-24	CLIP-seq
MIRT1290678	hsa-miR-3120-5p	CLIP-seq
MIRT1290683	hsa-miR-3143	CLIP-seq
MIRT2607962	hsa-miR-3148	CLIP-seq
MIRT1290689	hsa-miR-3529	CLIP-seq
MIRT2607963	hsa-miR-3688-3p	CLIP-seq
MIRT1290692	hsa-miR-369-3p	CLIP-seq
MIRT1290695	hsa-miR-374a	CLIP-seq
MIRT1290696	hsa-miR-374b	CLIP-seq
MIRT1290697	hsa-miR-379	CLIP-seq
MIRT2086476	hsa-miR-383	CLIP-seq
MIRT1290699	hsa-miR-410	CLIP-seq
MIRT2607964	hsa-miR-4274	CLIP-seq
MIRT1290702	hsa-miR-4275	CLIP-seq
MIRT2607965	hsa-miR-4282	CLIP-seq
MIRT1290707	hsa-miR-4436a	CLIP-seq
MIRT2607966	hsa-miR-4436b-5p	CLIP-seq
MIRT1290709	hsa-miR-4451	CLIP-seq
MIRT1290710	hsa-miR-4457	CLIP-seq
MIRT2607967	hsa-miR-4517	CLIP-seq
MIRT2607968	hsa-miR-4519	CLIP-seq
MIRT1290714	hsa-miR-4524	CLIP-seq
MIRT2311530	hsa-miR-4530	CLIP-seq
MIRT1290717	hsa-miR-4536	CLIP-seq
MIRT1290718	hsa-miR-4650-3p	CLIP-seq
MIRT1290719	hsa-miR-4652-3p	CLIP-seq
MIRT2607969	hsa-miR-4668-3p	CLIP-seq
MIRT2607970	hsa-miR-4680-3p	CLIP-seq
MIRT2607971	hsa-miR-4699-3p	CLIP-seq
MIRT1290723	hsa-miR-4700-3p	CLIP-seq
MIRT1290725	hsa-miR-4722-3p	CLIP-seq
MIRT1290726	hsa-miR-4731-3p	CLIP-seq
MIRT1290727	hsa-miR-4732-5p	CLIP-seq
MIRT2086489	hsa-miR-4772-5p	CLIP-seq
MIRT1290734	hsa-miR-4801	CLIP-seq
MIRT1290737	hsa-miR-501-3p	CLIP-seq
MIRT1290738	hsa-miR-502-3p	CLIP-seq
MIRT1290741	hsa-miR-511	CLIP-seq
MIRT1290754	hsa-miR-543	CLIP-seq
MIRT2607972	hsa-miR-548a-3p	CLIP-seq
MIRT2607973	hsa-miR-548c-3p	CLIP-seq
MIRT2607974	hsa-miR-548e	CLIP-seq
MIRT2607975	hsa-miR-548f	CLIP-seq
MIRT1290756	hsa-miR-577	CLIP-seq
MIRT2311550	hsa-miR-634	CLIP-seq
MIRT1290766	hsa-miR-891b	CLIP-seq
MIRT1290638	hsa-miR-103b	CLIP-seq
MIRT1290640	hsa-miR-1197	CLIP-seq
MIRT2689334	hsa-miR-1245b-3p	CLIP-seq
MIRT2607957	hsa-miR-127-5p	CLIP-seq
MIRT2607958	hsa-miR-1283	CLIP-seq
MIRT1290647	hsa-miR-1324	CLIP-seq
MIRT2607959	hsa-miR-141	CLIP-seq
MIRT1290648	hsa-miR-1470	CLIP-seq
MIRT1290649	hsa-miR-155	CLIP-seq
MIRT2607960	hsa-miR-1910	CLIP-seq
MIRT1290655	hsa-miR-19a	CLIP-seq
MIRT1290656	hsa-miR-19b	CLIP-seq
MIRT2607961	hsa-miR-200a	CLIP-seq
MIRT2689335	hsa-miR-2054	CLIP-seq
MIRT2086472	hsa-miR-2110	CLIP-seq
MIRT1290658	hsa-miR-2113	CLIP-seq
MIRT1290665	hsa-miR-24	CLIP-seq
MIRT1290678	hsa-miR-3120-5p	CLIP-seq
MIRT1290683	hsa-miR-3143	CLIP-seq
MIRT1290686	hsa-miR-3187-3p	CLIP-seq
MIRT1290688	hsa-miR-331-3p	CLIP-seq
MIRT1290689	hsa-miR-3529	CLIP-seq
MIRT2689336	hsa-miR-3617	CLIP-seq
MIRT1290697	hsa-miR-379	CLIP-seq
MIRT2689337	hsa-miR-380	CLIP-seq
MIRT1290699	hsa-miR-410	CLIP-seq
MIRT2689338	hsa-miR-411	CLIP-seq
MIRT2689339	hsa-miR-4263	CLIP-seq
MIRT2086478	hsa-miR-4271	CLIP-seq
MIRT2607964	hsa-miR-4274	CLIP-seq
MIRT1290702	hsa-miR-4275	CLIP-seq
MIRT2607965	hsa-miR-4282	CLIP-seq
MIRT1290705	hsa-miR-4328	CLIP-seq
MIRT1290707	hsa-miR-4436a	CLIP-seq
MIRT2607966	hsa-miR-4436b-5p	CLIP-seq
MIRT1290709	hsa-miR-4451	CLIP-seq
MIRT1290710	hsa-miR-4457	CLIP-seq
MIRT1290712	hsa-miR-4468	CLIP-seq
MIRT2607968	hsa-miR-4519	CLIP-seq
MIRT1290714	hsa-miR-4524	CLIP-seq
MIRT1290716	hsa-miR-4529-5p	CLIP-seq
MIRT2086483	hsa-miR-4533	CLIP-seq
MIRT1290717	hsa-miR-4536	CLIP-seq
MIRT1290718	hsa-miR-4650-3p	CLIP-seq
MIRT1290719	hsa-miR-4652-3p	CLIP-seq
MIRT1290721	hsa-miR-4667-3p	CLIP-seq
MIRT2086484	hsa-miR-4667-5p	CLIP-seq
MIRT2607971	hsa-miR-4699-3p	CLIP-seq
MIRT1290723	hsa-miR-4700-3p	CLIP-seq
MIRT2086486	hsa-miR-4700-5p	CLIP-seq
MIRT1290725	hsa-miR-4722-3p	CLIP-seq
MIRT2086487	hsa-miR-4725-3p	CLIP-seq
MIRT1290726	hsa-miR-4731-3p	CLIP-seq
MIRT1290727	hsa-miR-4732-5p	CLIP-seq
MIRT1290729	hsa-miR-4747-5p	CLIP-seq
MIRT2689340	hsa-miR-4799-5p	CLIP-seq
MIRT1290734	hsa-miR-4801	CLIP-seq
MIRT1290737	hsa-miR-501-3p	CLIP-seq
MIRT1290738	hsa-miR-502-3p	CLIP-seq
MIRT1290741	hsa-miR-511	CLIP-seq
MIRT1290754	hsa-miR-543	CLIP-seq
MIRT2689341	hsa-miR-548b-3p	CLIP-seq
MIRT2689342	hsa-miR-552	CLIP-seq
MIRT2689343	hsa-miR-576-5p	CLIP-seq
MIRT1290756	hsa-miR-577	CLIP-seq
MIRT2689344	hsa-miR-641	CLIP-seq
MIRT1290759	hsa-miR-642a	CLIP-seq
MIRT1290766	hsa-miR-891b	CLIP-seq

Show/Hide all (90)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	NAS	10934204
GO:0001568	Process	Blood vessel development	ISS
GO:0001764	Process	Neuron migration	ISS
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IDA	10608883, 10801446, 12391161, 16272156
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005096	Function	GTPase activator activity	IDA	10934204
GO:0005096	Function	GTPase activator activity	IEA
GO:0005509	Function	Calcium ion binding	NAS	10934204
GO:0005515	Function	Protein binding	IPI	10548487, 10608844, 11168587, 11359771, 11598133, 12391161, 15161933, 23885123, 35271311
GO:0005737	Component	Cytoplasm	IDA	11359771, 17724123
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005770	Component	Late endosome	IDA	17724123
GO:0005770	Component	Late endosome	IEA
GO:0005829	Component	Cytosol	IDA	22797597
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	NAS	10934204
GO:0005911	Component	Cell-cell junction	ISS
GO:0005923	Component	Bicellular tight junction	IDA	23885123
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IDA	23800469
GO:0007188	Process	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IDA	23800469
GO:0007218	Process	Neuropeptide signaling pathway	IDA	23800469
GO:0007264	Process	Small GTPase-mediated signal transduction	IEA
GO:0007264	Process	Small GTPase-mediated signal transduction	TAS	10608883, 10934204
GO:0007265	Process	Ras protein signal transduction	IBA
GO:0007399	Process	Nervous system development	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	16272156
GO:0010975	Process	Regulation of neuron projection development	IEA
GO:0010976	Process	Positive regulation of neuron projection development	ISS
GO:0016020	Component	Membrane	IDA	10608883
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IBA
GO:0016324	Component	Apical plasma membrane	IDA	22797597
GO:0016324	Component	Apical plasma membrane	IEA
GO:0019933	Process	CAMP-mediated signaling	NAS	10934204
GO:0019992	Function	Diacylglycerol binding	NAS	10934204
GO:0021591	Process	Ventricular system development	ISS
GO:0021884	Process	Forebrain neuron development	ISS
GO:0030033	Process	Microvillus assembly	IEA
GO:0030139	Component	Endocytic vesicle	IBA
GO:0030139	Component	Endocytic vesicle	IDA	22797597
GO:0030154	Process	Cell differentiation	IEA
GO:0030165	Function	PDZ domain binding	IDA	10548487, 11168587, 12391161
GO:0030552	Function	CAMP binding	IDA	10548487, 10608844, 11359771
GO:0030552	Function	CAMP binding	IDA	10801446
GO:0030553	Function	CGMP binding	IDA	10608844, 11359771
GO:0031175	Process	Neuron projection development	IDA	23800469
GO:0031547	Process	Brain-derived neurotrophic factor receptor signaling pathway	ISS
GO:0031697	Function	Beta-1 adrenergic receptor binding	IDA	12391161
GO:0032092	Process	Positive regulation of protein binding	ISS
GO:0032486	Process	Rap protein signal transduction	IMP	21840392
GO:0032991	Component	Protein-containing complex	ISS
GO:0035556	Process	Intracellular signal transduction	TAS	10608883
GO:0038180	Process	Nerve growth factor signaling pathway	ISS
GO:0043005	Component	Neuron projection	ISS
GO:0043025	Component	Neuronal cell body	ISS
GO:0043547	Process	Positive regulation of GTPase activity	IDA	10548487, 10608844, 10801446, 11359771, 16272156, 17724123, 23800469
GO:0043547	Process	Positive regulation of GTPase activity	IMP	21840392
GO:0045202	Component	Synapse	ISS
GO:0045860	Process	Positive regulation of protein kinase activity	IDA	11359771, 23800469
GO:0048022	Process	Negative regulation of melanin biosynthetic process	ISS
GO:0048167	Process	Regulation of synaptic plasticity	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	11359771
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050699	Function	WW domain binding	IDA	10548487, 11598133
GO:0050774	Process	Negative regulation of dendrite morphogenesis	IDA	16272156
GO:0061028	Process	Establishment of endothelial barrier	IMP	21840392
GO:0070161	Component	Anchoring junction	IEA
GO:0070300	Function	Phosphatidic acid binding	IDA	22797597
GO:0070300	Function	Phosphatidic acid binding	IEA
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IDA	16272156, 23800469
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IEA
GO:0071320	Process	Cellular response to cAMP	IDA	10801446, 16272156, 21840392, 23800469
GO:0071321	Process	Cellular response to cGMP	IDA	10801446
GO:0071880	Process	Adenylate cyclase-activating adrenergic receptor signaling pathway	IDA	12391161
GO:0072659	Process	Protein localization to plasma membrane	IEA
GO:0090557	Process	Establishment of endothelial intestinal barrier	IMP	23885123
GO:1901888	Process	Regulation of cell junction assembly	IMP	21840392
GO:1903698	Process	Positive regulation of microvillus assembly	IGI	22797597
GO:1990090	Process	Cellular response to nerve growth factor stimulus	ISS
GO:2000481	Process	Positive regulation of cAMP-dependent protein kinase activity	IDA	16272156
GO:2000670	Process	Positive regulation of dendritic cell apoptotic process	IDA	16272156
GO:2001214	Process	Positive regulation of vasculogenesis	ISS
GO:2001224	Process	Positive regulation of neuron migration	ISS

MIM	HGNC	e!Ensembl
609530	16854	ENSG00000109756

Q9Y4G8

Protein name

Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)

Protein function

Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in

PDB

6QDT

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00618	RasGEF_N	270 → 357	RasGEF N-terminal motif	Domain
PF00595	PDZ	386 → 465	PDZ domain	Domain
PF00788	RA	606 → 692	Ras association (RalGDS/AF-6) domain	Domain
PF00617	RasGEF	720 → 898	RasGEF domain	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in primary neuronal and endocrine cells (at protein level). Highest expression levels in brain. Lower expression levels in heart, kidney, lung, placenta and blood leukocytes. {ECO:0000269|PubMed:10934204, ECO:0000269|PubMed:1

Sequence

MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS
DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD
DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS
VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK
NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL
TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN
LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS
KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE
KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT
RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS
ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE
GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE
VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN
QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL
QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI
AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS
FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE
TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS
PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGYTLAPSGTVDNF
SDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQY
SLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNI
QTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQA
QSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAV
ASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVAR
SSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV

Sequence length

1499

Interactions

View interactions

	KEGG		Reactome
	MAPK signaling pathway Rap1 signaling pathway Tight junction		RAF/MAP kinase cascade

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AMYOTROPHIC LATERAL SCLEROSIS	—	Disgenet, GenCC Disgenet, GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EPILEPSIES, MYOCLONIC	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy, familial adult myoclonic, 7	Benign; Uncertain significance	ClinVar ClinVar, Disgenet, GWAS catalog, HPO ClinVar, Disgenet, GWAS catalog, HPO ClinVar, Disgenet, GWAS catalog, HPO	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
FAMILIAL ADULT MYOCLONIC EPILEPSY	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCLONIC EPILEPSY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (17)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Aneuploidy	Aneuploidy	Pubtator	25332235	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Benign adult familial myoclonic epilepsy	Benign Myoclonic Epilepsy	BEFREE	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Benign Infantile Myoclonic Epilepsy	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Early Childhood Epilepsy, Myoclonic	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	31483537		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy, Myoclonic, Infantile	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulosclerosis (disorder)	Glomerulosclerosis	BEFREE	31171376		★★★★★ ★☆☆☆☆ Found in Text Mining only
Idiopathic Myoclonic Epilepsy	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Infantile Severe Myoclonic Epilepsy	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myoclonic Absence Epilepsy	Myotonia Levior	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myoclonic Astatic Epilepsy	Myoclonic Astatic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myoclonic Encephalopathy	Myoclonic Encephalopathy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myoclonic Epilepsy	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nephrosis, congenital	Nephrosis, Congenital	BEFREE	31171376		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	28917843		★★★★★ ★☆☆☆☆ Found in Text Mining only
Subcortical Band Heterotopia	Subcortical Band Heterotopia	BEFREE	29747665		★★★★★ ★☆☆☆☆ Found in Text Mining only
Symptomatic Myoclonic Epilepsy	Myoclonic Epilepsy	CTD_human_DG	29507423		★★★★★ ★☆☆☆☆ Found in Text Mining only

RAPGEF2 (Rap guanine nucleotide exchange factor 2)