Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	9659
Gene name	Phosphodiesterase 4D interacting protein
Gene symbol	PDE4DIP
Synonyms (NCBI Gene)	CMYA2MMGL
Chromosome	1
Chromosome location	1q21.2
Summary	The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding

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Show/Hide all (156)

miRTarBase ID	miRNA	Experiments	Reference
MIRT052625	hsa-let-7a-5p	CLASH	23622248
MIRT049067	hsa-miR-92a-3p	CLASH	23622248
MIRT041047	hsa-miR-505-3p	CLASH	23622248
MIRT717486	hsa-miR-3614-3p	HITS-CLIP	19536157
MIRT717485	hsa-miR-1245a	HITS-CLIP	19536157
MIRT717484	hsa-miR-8079	HITS-CLIP	19536157
MIRT717483	hsa-miR-6513-3p	HITS-CLIP	19536157
MIRT717482	hsa-miR-5193	HITS-CLIP	19536157
MIRT717481	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT717480	hsa-miR-6734-3p	HITS-CLIP	19536157
MIRT717479	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT717478	hsa-miR-1297	HITS-CLIP	19536157
MIRT717477	hsa-miR-26a-5p	HITS-CLIP	19536157
MIRT717476	hsa-miR-26b-5p	HITS-CLIP	19536157
MIRT717475	hsa-miR-4465	HITS-CLIP	19536157
MIRT717474	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23706177
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23706177
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23706177
MIRT528669	hsa-miR-3618	HITS-CLIP	23706177
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23706177
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23706177
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23706177
MIRT528669	hsa-miR-3618	HITS-CLIP	23706177
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23824327
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23824327
MIRT488398	hsa-miR-3976	HITS-CLIP	23824327
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23824327
MIRT528669	hsa-miR-3618	HITS-CLIP	23824327
MIRT528668	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23824327
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23824327
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23824327
MIRT528669	hsa-miR-3618	HITS-CLIP	23824327
MIRT528668	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT488400	hsa-miR-6758-5p	PAR-CLIP	22012620
MIRT488399	hsa-miR-6856-5p	PAR-CLIP	22012620
MIRT528670	hsa-miR-139-5p	PAR-CLIP	22012620
MIRT528669	hsa-miR-3618	PAR-CLIP	22012620
MIRT528668	hsa-miR-582-5p	PAR-CLIP	22012620
MIRT528667	hsa-miR-452-3p	PAR-CLIP	22012620
MIRT488401	hsa-miR-3121-3p	PAR-CLIP	23592263
MIRT488400	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT488399	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT488398	hsa-miR-3976	PAR-CLIP	23592263
MIRT488397	hsa-miR-432-5p	PAR-CLIP	23592263
MIRT488396	hsa-miR-539-5p	PAR-CLIP	23592263
MIRT488395	hsa-miR-4434	PAR-CLIP	23592263
MIRT488394	hsa-miR-4516	PAR-CLIP	23592263
MIRT488393	hsa-miR-5703	PAR-CLIP	23592263
MIRT488392	hsa-miR-4531	PAR-CLIP	23592263
MIRT488391	hsa-miR-1270	PAR-CLIP	23592263
MIRT488390	hsa-miR-620	PAR-CLIP	23592263
MIRT440015	hsa-miR-493-3p	HITS-CLIP	24374217
MIRT440015	hsa-miR-493-3p	HITS-CLIP	24374217
MIRT528670	hsa-miR-139-5p	HITS-CLIP	27418678
MIRT528669	hsa-miR-3618	HITS-CLIP	27418678
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	27418678
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	27418678
MIRT717486	hsa-miR-3614-3p	HITS-CLIP	19536157
MIRT717485	hsa-miR-1245a	HITS-CLIP	19536157
MIRT717484	hsa-miR-8079	HITS-CLIP	19536157
MIRT717483	hsa-miR-6513-3p	HITS-CLIP	19536157
MIRT717482	hsa-miR-5193	HITS-CLIP	19536157
MIRT717481	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT717480	hsa-miR-6734-3p	HITS-CLIP	19536157
MIRT717479	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT717478	hsa-miR-1297	HITS-CLIP	19536157
MIRT717477	hsa-miR-26a-5p	HITS-CLIP	19536157
MIRT717476	hsa-miR-26b-5p	HITS-CLIP	19536157
MIRT717475	hsa-miR-4465	HITS-CLIP	19536157
MIRT717474	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23706177
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23706177
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23706177
MIRT528669	hsa-miR-3618	HITS-CLIP	23706177
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23706177
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23706177
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23706177
MIRT528669	hsa-miR-3618	HITS-CLIP	23706177
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23824327
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23824327
MIRT488398	hsa-miR-3976	HITS-CLIP	23824327
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23824327
MIRT528669	hsa-miR-3618	HITS-CLIP	23824327
MIRT528668	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT488400	hsa-miR-6758-5p	HITS-CLIP	23824327
MIRT488399	hsa-miR-6856-5p	HITS-CLIP	23824327
MIRT528670	hsa-miR-139-5p	HITS-CLIP	23824327
MIRT528669	hsa-miR-3618	HITS-CLIP	23824327
MIRT528668	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT488400	hsa-miR-6758-5p	PAR-CLIP	22012620
MIRT488399	hsa-miR-6856-5p	PAR-CLIP	22012620
MIRT528670	hsa-miR-139-5p	PAR-CLIP	22012620
MIRT528669	hsa-miR-3618	PAR-CLIP	22012620
MIRT528668	hsa-miR-582-5p	PAR-CLIP	22012620
MIRT528667	hsa-miR-452-3p	PAR-CLIP	22012620
MIRT488401	hsa-miR-3121-3p	PAR-CLIP	23592263
MIRT488400	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT488399	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT488398	hsa-miR-3976	PAR-CLIP	23592263
MIRT488397	hsa-miR-432-5p	PAR-CLIP	23592263
MIRT488396	hsa-miR-539-5p	PAR-CLIP	23592263
MIRT488395	hsa-miR-4434	PAR-CLIP	23592263
MIRT488394	hsa-miR-4516	PAR-CLIP	23592263
MIRT488393	hsa-miR-5703	PAR-CLIP	23592263
MIRT488392	hsa-miR-4531	PAR-CLIP	23592263
MIRT488391	hsa-miR-1270	PAR-CLIP	23592263
MIRT488390	hsa-miR-620	PAR-CLIP	23592263
MIRT1220674	hsa-miR-1294	CLIP-seq
MIRT1220675	hsa-miR-31	CLIP-seq
MIRT1220676	hsa-miR-3126-5p	CLIP-seq
MIRT1220677	hsa-miR-3688-5p	CLIP-seq
MIRT1220678	hsa-miR-4316	CLIP-seq
MIRT1220679	hsa-miR-4419a	CLIP-seq
MIRT1220680	hsa-miR-450b-5p	CLIP-seq
MIRT1220681	hsa-miR-4510	CLIP-seq
MIRT1220682	hsa-miR-498	CLIP-seq
MIRT1220683	hsa-miR-513a-3p	CLIP-seq
MIRT1220684	hsa-miR-548p	CLIP-seq
MIRT2439248	hsa-miR-3157-5p	CLIP-seq
MIRT2439249	hsa-miR-4303	CLIP-seq
MIRT2439250	hsa-miR-4649-3p	CLIP-seq
MIRT2456108	hsa-miR-3134	CLIP-seq
MIRT2456109	hsa-miR-3688-3p	CLIP-seq
MIRT2456110	hsa-miR-3907	CLIP-seq
MIRT2456111	hsa-miR-3978	CLIP-seq
MIRT2456112	hsa-miR-4534	CLIP-seq
MIRT2456113	hsa-miR-508-5p	CLIP-seq
MIRT2456114	hsa-miR-522	CLIP-seq
MIRT2456108	hsa-miR-3134	CLIP-seq
MIRT2589886	hsa-miR-3182	CLIP-seq
MIRT2589887	hsa-miR-339-5p	CLIP-seq
MIRT2456109	hsa-miR-3688-3p	CLIP-seq
MIRT2456110	hsa-miR-3907	CLIP-seq
MIRT2456111	hsa-miR-3978	CLIP-seq
MIRT2589888	hsa-miR-4421	CLIP-seq
MIRT2456112	hsa-miR-4534	CLIP-seq
MIRT2456114	hsa-miR-522	CLIP-seq
MIRT2687431	hsa-miR-1299	CLIP-seq
MIRT2589886	hsa-miR-3182	CLIP-seq
MIRT2687432	hsa-miR-378	CLIP-seq
MIRT2687433	hsa-miR-378b	CLIP-seq
MIRT2687434	hsa-miR-378c	CLIP-seq
MIRT2687435	hsa-miR-378d	CLIP-seq
MIRT2687436	hsa-miR-378e	CLIP-seq
MIRT2687437	hsa-miR-378f	CLIP-seq
MIRT2687438	hsa-miR-378h	CLIP-seq
MIRT2687439	hsa-miR-378i	CLIP-seq
MIRT2687440	hsa-miR-422a	CLIP-seq
MIRT2687441	hsa-miR-4469	CLIP-seq
MIRT2687442	hsa-miR-4638-3p	CLIP-seq
MIRT2687443	hsa-miR-4782-5p	CLIP-seq
MIRT2687444	hsa-miR-516b	CLIP-seq
MIRT2687445	hsa-miR-642a	CLIP-seq
MIRT2687446	hsa-miR-711	CLIP-seq

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17923693, 21569246, 21900206, 25416956, 25910212, 26496610, 26871637, 27666745, 29162697, 29961565, 30021884, 31413325, 31515488, 32296183, 32353859, 32814053, 33060197, 33961781, 35271311, 36217030
GO:0005634	Component	Nucleus	IDA	11374908
GO:0005737	Component	Cytoplasm	IDA	11374908
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	27666745
GO:0005794	Component	Golgi apparatus	IEA
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005813	Component	Centrosome	IEA
GO:0005813	Component	Centrosome	ISS	11134006
GO:0005815	Component	Microtubule organizing center	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0007098	Process	Centrosome cycle	IBA
GO:0019899	Function	Enzyme binding	ISS	11134006
GO:0030016	Component	Myofibril	ISS	11134006
GO:0030953	Process	Astral microtubule organization	IMP	29162697
GO:0060090	Function	Molecular adaptor activity	IBA
GO:0060090	Function	Molecular adaptor activity	IDA	27666745
GO:0065003	Process	Protein-containing complex assembly	ISS	11134006
GO:0090063	Process	Positive regulation of microtubule nucleation	IMP	29162697
GO:1903358	Process	Regulation of Golgi organization	IBA
GO:1903358	Process	Regulation of Golgi organization	IDA	27666745
GO:1903754	Component	Cortical microtubule plus-end	IDA	29162697

MIM	HGNC	e!Ensembl
608117	15580	ENSG00000178104

Q5VU43

Protein name

Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)

Protein function

Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). ; [Isoform 13]: Participates in microtubule dynamics, promoting microtubule assemb

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07989	Cnn_1N	5 → 76	Centrosomin N-terminal motif 1	Coiled-coil
PF06758	Olduvai	1556 → 1623	Olduvai domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in adult and fetal heart, in skeletal muscle and, to a lower extent, in brain and placenta. {ECO:0000269|PubMed:11374908}.

Sequence

MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR
ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK
NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQ
SLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSH
LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEEL
YQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQR
VVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRA
WEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQR
IHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESL
LRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSAT
LLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQ
AAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQI
PSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQ
SMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREK
VASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERD
RTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEE
AAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEK
RKAEEELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKG
EVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKLTPELLV
HLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRD
PGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESL
VKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRG
STLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVR
SLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLES
LIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICY
LITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQA
GLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEAC
SDMDIVSEYTHYEEKKASPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISLPT
PQNTPKEANQAHSGFHFHSIPKLASLPQAPLPSAPSSFLPFSPTGPLLLGCCETPVVSLA
EAQQELQMLQKQLGESASTVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRIL
EPGYLGSSGKWDVMRPQKGSVSGDLSSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRLEE
SICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH
VSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLS
LQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYSLDACHQIPL
SSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDP
GNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANGLGLDTSPVMKTP
PKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKLLVKKIVSLVRSACSFPGLEAQ
GTEVLGSKGIHELRSSTSALHHALEESASLLTMFWRAALPSTHIPVLPGKVGESTERELL
ELRTKVSKQERLLQSTTEHLKNANQQKESMEQFIVSQLTRTHDVLKKARTNLEVKSLRAL
PCTPAL

Sequence length

2346

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CUTANEOUS MASTOCYTOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MACROVASCULAR COMPLICATIONS OF DIABETES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MASTOCYTOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (31)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	32471155	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Arrhythmias Cardiac	Cardiac arrhythmias	Pubtator	34289528	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	23046476	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial fibrillation	Pubtator	34289528	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Basal Cell	Basal cell carcinoma	Pubtator	33928395	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	35602894	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Merkel Cell	Merkel cell carcinoma	Pubtator	25531179	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Ischemic stroke	Pubtator	25961151	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Ischemic stroke	Pubtator	25961151, 36691064	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34573430	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37355626	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cushing's symphalangism	Proximal symphalangism	Pubtator	25961151	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dementia	Dementia	Pubtator	32471155	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dementia Vascular	Vascular dementia	Pubtator	32471155	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	33430853	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Neuropathies	Diabetic neuropathy	Pubtator	33430853	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Eye Diseases	Eye disease	Pubtator	36490268	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Frontotemporal Dementia	Frontotemporal dementia	Pubtator	32471155	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastroschisis	Gastroschisis	Pubtator	31075877, 32163230	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intestinal Neoplasms	Intestinal neoplasm	Pubtator	37355626	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	25961151		★★★★★ ★☆☆☆☆ Found in Text Mining only
Langer Mesomelic Dysplasia Syndrome	Langer Mesomelic Dysplasia Syndrome	BEFREE	29604399		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	32638549	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liposarcoma	Liposarcoma	Pubtator	36464833	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	27513329	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Medullary carcinoma of thyroid	Megalencephaly, Polymicrogyria, Polydactyly, Hydrocephalus Syndrome	BEFREE	30120715		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mucopolysaccharidosis I	Mucopolysaccharidosis	Pubtator	32880920	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30120715, 31480474		★★★★★ ★☆☆☆☆ Found in Text Mining only
pineoblastoma	Pineoblastoma	BEFREE	30030436		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	LHGDN	17143517		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	17143517		★★★★★ ★☆☆☆☆ Found in Text Mining only

PDE4DIP (phosphodiesterase 4D interacting protein)