HS2ST1 (heparan sulfate 2-O-sulfotransferase 1)

Gene

• Entrez ID: 9653
• Gene name: Heparan sulfate 2-O-sulfotransferase 1
• Gene symbol: HS2ST1
• Synonyms (NCBI Gene): 2-OST, NFSRA, dJ604K5.2
• Chromosome: 1
• Chromosome location: 1p22.3
• Summary: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that trans

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022975	hsa-miR-124-3p	Microarray	18668037
MIRT023971	hsa-miR-1-3p	Microarray	18668037
MIRT032481	hsa-let-7b-5p	Proteomics	18668040
MIRT242651	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT523137	hsa-miR-205-3p	HITS-CLIP	21572407
MIRT509179	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509178	hsa-miR-3924	HITS-CLIP	21572407
MIRT523136	hsa-miR-130a-5p	HITS-CLIP	21572407
MIRT523135	hsa-miR-23a-3p	HITS-CLIP	21572407
MIRT523134	hsa-miR-23b-3p	HITS-CLIP	21572407
MIRT523133	hsa-miR-23c	HITS-CLIP	21572407
MIRT509177	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT693021	hsa-miR-7-1-3p	HITS-CLIP	23313552
MIRT693020	hsa-miR-7-2-3p	HITS-CLIP	23313552
MIRT693019	hsa-miR-1273d	HITS-CLIP	23313552
MIRT693018	hsa-miR-8084	HITS-CLIP	23313552
MIRT693017	hsa-miR-4328	HITS-CLIP	23313552
MIRT693016	hsa-miR-4434	HITS-CLIP	23313552
MIRT693015	hsa-miR-4516	HITS-CLIP	23313552
MIRT693014	hsa-miR-5703	HITS-CLIP	23313552
MIRT693013	hsa-miR-520d-5p	HITS-CLIP	23313552
MIRT693012	hsa-miR-524-5p	HITS-CLIP	23313552
MIRT693011	hsa-miR-4531	HITS-CLIP	23313552
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT523137	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT509178	hsa-miR-3924	PAR-CLIP	20371350
MIRT523136	hsa-miR-130a-5p	PAR-CLIP	20371350
MIRT523135	hsa-miR-23a-3p	PAR-CLIP	20371350
MIRT523134	hsa-miR-23b-3p	PAR-CLIP	20371350
MIRT523133	hsa-miR-23c	PAR-CLIP	20371350
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT523137	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509178	hsa-miR-3924	PAR-CLIP	21572407
MIRT523136	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT523135	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT523134	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT523133	hsa-miR-23c	PAR-CLIP	21572407
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509178	hsa-miR-3924	PAR-CLIP	21572407
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT523137	hsa-miR-205-3p	PAR-CLIP	23446348
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509178	hsa-miR-3924	PAR-CLIP	23446348
MIRT523136	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT523135	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT523134	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT523133	hsa-miR-23c	PAR-CLIP	23446348
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509178	hsa-miR-3924	PAR-CLIP	23446348
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT441823	hsa-miR-651-3p	PAR-CLIP	22291592
MIRT441823	hsa-miR-651-3p	PAR-CLIP	22100165
MIRT441823	hsa-miR-651-3p	PAR-CLIP	22100165
MIRT242651	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT523137	hsa-miR-205-3p	HITS-CLIP	21572407
MIRT509179	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509178	hsa-miR-3924	HITS-CLIP	21572407
MIRT523136	hsa-miR-130a-5p	HITS-CLIP	21572407
MIRT523135	hsa-miR-23a-3p	HITS-CLIP	21572407
MIRT523134	hsa-miR-23b-3p	HITS-CLIP	21572407
MIRT523133	hsa-miR-23c	HITS-CLIP	21572407
MIRT509177	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT693021	hsa-miR-7-1-3p	HITS-CLIP	23313552
MIRT693020	hsa-miR-7-2-3p	HITS-CLIP	23313552
MIRT693019	hsa-miR-1273d	HITS-CLIP	23313552
MIRT693018	hsa-miR-8084	HITS-CLIP	23313552
MIRT693017	hsa-miR-4328	HITS-CLIP	23313552
MIRT693016	hsa-miR-4434	HITS-CLIP	23313552
MIRT693015	hsa-miR-4516	HITS-CLIP	23313552
MIRT693014	hsa-miR-5703	HITS-CLIP	23313552
MIRT693013	hsa-miR-520d-5p	HITS-CLIP	23313552
MIRT693012	hsa-miR-524-5p	HITS-CLIP	23313552
MIRT693011	hsa-miR-4531	HITS-CLIP	23313552
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT523137	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT509178	hsa-miR-3924	PAR-CLIP	20371350
MIRT523136	hsa-miR-130a-5p	PAR-CLIP	20371350
MIRT523135	hsa-miR-23a-3p	PAR-CLIP	20371350
MIRT523134	hsa-miR-23b-3p	PAR-CLIP	20371350
MIRT523133	hsa-miR-23c	PAR-CLIP	20371350
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT523137	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509178	hsa-miR-3924	PAR-CLIP	21572407
MIRT523136	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT523135	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT523134	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT523133	hsa-miR-23c	PAR-CLIP	21572407
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509178	hsa-miR-3924	PAR-CLIP	21572407
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT523137	hsa-miR-205-3p	PAR-CLIP	23446348
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509178	hsa-miR-3924	PAR-CLIP	23446348
MIRT523136	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT523135	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT523134	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT523133	hsa-miR-23c	PAR-CLIP	23446348
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT242651	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509179	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509178	hsa-miR-3924	PAR-CLIP	23446348
MIRT509177	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT441823	hsa-miR-651-3p	PAR-CLIP	22291592
MIRT441823	hsa-miR-651-3p	PAR-CLIP	22100165
MIRT441823	hsa-miR-651-3p	PAR-CLIP	22100165
MIRT1054806	hsa-let-7a	CLIP-seq
MIRT1054807	hsa-let-7b	CLIP-seq
MIRT1054808	hsa-let-7c	CLIP-seq
MIRT1054809	hsa-let-7d	CLIP-seq
MIRT1054810	hsa-let-7e	CLIP-seq
MIRT1054811	hsa-let-7f	CLIP-seq
MIRT1054812	hsa-let-7g	CLIP-seq
MIRT1054813	hsa-let-7i	CLIP-seq
MIRT1054814	hsa-miR-1178	CLIP-seq
MIRT1054815	hsa-miR-1224-5p	CLIP-seq
MIRT1054816	hsa-miR-125a-5p	CLIP-seq
MIRT1054817	hsa-miR-125b	CLIP-seq
MIRT1054818	hsa-miR-1289	CLIP-seq
MIRT1054819	hsa-miR-1294	CLIP-seq
MIRT1054820	hsa-miR-129-5p	CLIP-seq
MIRT1054821	hsa-miR-1304	CLIP-seq
MIRT1054822	hsa-miR-1305	CLIP-seq
MIRT1054823	hsa-miR-132	CLIP-seq
MIRT1054824	hsa-miR-146b-3p	CLIP-seq
MIRT1054825	hsa-miR-1827	CLIP-seq
MIRT1054826	hsa-miR-183	CLIP-seq
MIRT1054827	hsa-miR-198	CLIP-seq
MIRT1054828	hsa-miR-202	CLIP-seq
MIRT1054829	hsa-miR-212	CLIP-seq
MIRT1054830	hsa-miR-214	CLIP-seq
MIRT1054831	hsa-miR-2276	CLIP-seq
MIRT1054832	hsa-miR-2964a-5p	CLIP-seq
MIRT1054833	hsa-miR-300	CLIP-seq
MIRT1054834	hsa-miR-3074-3p	CLIP-seq
MIRT1054835	hsa-miR-3120-3p	CLIP-seq
MIRT1054836	hsa-miR-3143	CLIP-seq
MIRT1054837	hsa-miR-3157-5p	CLIP-seq
MIRT1054838	hsa-miR-3164	CLIP-seq
MIRT1054839	hsa-miR-3198	CLIP-seq
MIRT1054840	hsa-miR-323b-3p	CLIP-seq
MIRT1054841	hsa-miR-329	CLIP-seq
MIRT1054842	hsa-miR-34b	CLIP-seq
MIRT1054843	hsa-miR-3619-5p	CLIP-seq
MIRT1054844	hsa-miR-362-3p	CLIP-seq
MIRT1054845	hsa-miR-3646	CLIP-seq
MIRT1054846	hsa-miR-3671	CLIP-seq
MIRT1054847	hsa-miR-369-3p	CLIP-seq
MIRT1054848	hsa-miR-375	CLIP-seq
MIRT1054849	hsa-miR-381	CLIP-seq
MIRT1054850	hsa-miR-3915	CLIP-seq
MIRT1054851	hsa-miR-3919	CLIP-seq
MIRT1054852	hsa-miR-3928	CLIP-seq
MIRT1054853	hsa-miR-3929	CLIP-seq
MIRT1054854	hsa-miR-3941	CLIP-seq
MIRT1054855	hsa-miR-3977	CLIP-seq
MIRT1054856	hsa-miR-4252	CLIP-seq
MIRT1054857	hsa-miR-4263	CLIP-seq
MIRT1054858	hsa-miR-4264	CLIP-seq
MIRT1054859	hsa-miR-4276	CLIP-seq
MIRT1054860	hsa-miR-4294	CLIP-seq
MIRT1054861	hsa-miR-4309	CLIP-seq
MIRT1054862	hsa-miR-4311	CLIP-seq
MIRT1054863	hsa-miR-4316	CLIP-seq
MIRT1054864	hsa-miR-4319	CLIP-seq
MIRT1054865	hsa-miR-4419b	CLIP-seq
MIRT1054866	hsa-miR-4420	CLIP-seq
MIRT1054867	hsa-miR-4446-5p	CLIP-seq
MIRT1054868	hsa-miR-4458	CLIP-seq
MIRT1054869	hsa-miR-4477b	CLIP-seq
MIRT1054870	hsa-miR-4478	CLIP-seq
MIRT1054871	hsa-miR-4500	CLIP-seq
MIRT1054872	hsa-miR-4652-3p	CLIP-seq
MIRT1054873	hsa-miR-4659a-3p	CLIP-seq
MIRT1054874	hsa-miR-4659b-3p	CLIP-seq
MIRT1054875	hsa-miR-4670-3p	CLIP-seq
MIRT1054876	hsa-miR-4677-3p	CLIP-seq
MIRT1054877	hsa-miR-4678	CLIP-seq
MIRT1054878	hsa-miR-4689	CLIP-seq
MIRT1054879	hsa-miR-4691-3p	CLIP-seq
MIRT1054880	hsa-miR-4698	CLIP-seq
MIRT1054881	hsa-miR-4708-5p	CLIP-seq
MIRT1054882	hsa-miR-4712-5p	CLIP-seq
MIRT1054883	hsa-miR-4719	CLIP-seq
MIRT1054884	hsa-miR-4725-5p	CLIP-seq
MIRT1054885	hsa-miR-4731-3p	CLIP-seq
MIRT1054886	hsa-miR-4732-3p	CLIP-seq
MIRT1054887	hsa-miR-4735-5p	CLIP-seq
MIRT1054888	hsa-miR-4755-5p	CLIP-seq
MIRT1054889	hsa-miR-4756-3p	CLIP-seq
MIRT1054890	hsa-miR-4765	CLIP-seq
MIRT1054891	hsa-miR-4773	CLIP-seq
MIRT1054892	hsa-miR-4778-5p	CLIP-seq
MIRT1054893	hsa-miR-4789-3p	CLIP-seq
MIRT1054894	hsa-miR-4795-3p	CLIP-seq
MIRT1054895	hsa-miR-4797-3p	CLIP-seq
MIRT1054896	hsa-miR-4801	CLIP-seq
MIRT1054897	hsa-miR-4802-3p	CLIP-seq
MIRT1054898	hsa-miR-494	CLIP-seq
MIRT1054899	hsa-miR-495	CLIP-seq
MIRT1054900	hsa-miR-504	CLIP-seq
MIRT1054901	hsa-miR-513c	CLIP-seq
MIRT1054902	hsa-miR-514b-5p	CLIP-seq
MIRT1054903	hsa-miR-539	CLIP-seq
MIRT1054904	hsa-miR-543	CLIP-seq
MIRT1054905	hsa-miR-548aa	CLIP-seq
MIRT1054906	hsa-miR-548n	CLIP-seq
MIRT1054907	hsa-miR-548t	CLIP-seq
MIRT1054908	hsa-miR-561	CLIP-seq
MIRT1054909	hsa-miR-576-5p	CLIP-seq
MIRT1054910	hsa-miR-577	CLIP-seq
MIRT1054911	hsa-miR-579	CLIP-seq
MIRT1054912	hsa-miR-595	CLIP-seq
MIRT1054913	hsa-miR-603	CLIP-seq
MIRT1054914	hsa-miR-607	CLIP-seq
MIRT1054915	hsa-miR-653	CLIP-seq
MIRT1054916	hsa-miR-670	CLIP-seq
MIRT1054917	hsa-miR-7	CLIP-seq
MIRT1054918	hsa-miR-761	CLIP-seq
MIRT1054919	hsa-miR-770-5p	CLIP-seq
MIRT1054920	hsa-miR-98	CLIP-seq
MIRT1549640	hsa-miR-345	CLIP-seq
MIRT1054858	hsa-miR-4264	CLIP-seq
MIRT1549641	hsa-miR-4522	CLIP-seq
MIRT1054895	hsa-miR-4797-3p	CLIP-seq
MIRT1920492	hsa-miR-3545-3p	CLIP-seq
MIRT1920493	hsa-miR-4774-5p	CLIP-seq
MIRT1920494	hsa-miR-582-3p	CLIP-seq
MIRT1920492	hsa-miR-3545-3p	CLIP-seq
MIRT1920493	hsa-miR-4774-5p	CLIP-seq
MIRT1920494	hsa-miR-582-3p	CLIP-seq
MIRT1920492	hsa-miR-3545-3p	CLIP-seq
MIRT1920493	hsa-miR-4774-5p	CLIP-seq
MIRT1920494	hsa-miR-582-3p	CLIP-seq
MIRT2012482	hsa-miR-27a	CLIP-seq
MIRT2012483	hsa-miR-27b	CLIP-seq
MIRT1054835	hsa-miR-3120-3p	CLIP-seq
MIRT2012484	hsa-miR-3192	CLIP-seq
MIRT2012485	hsa-miR-3714	CLIP-seq
MIRT2012486	hsa-miR-3978	CLIP-seq
MIRT1054857	hsa-miR-4263	CLIP-seq
MIRT1054859	hsa-miR-4276	CLIP-seq
MIRT2012487	hsa-miR-4314	CLIP-seq
MIRT2012488	hsa-miR-4493	CLIP-seq
MIRT2012489	hsa-miR-4646-5p	CLIP-seq
MIRT1054882	hsa-miR-4712-5p	CLIP-seq
MIRT2012490	hsa-miR-4796-5p	CLIP-seq
MIRT2012491	hsa-miR-4803	CLIP-seq
MIRT2012492	hsa-miR-513a-5p	CLIP-seq
MIRT1054909	hsa-miR-576-5p	CLIP-seq
MIRT1054911	hsa-miR-579	CLIP-seq
MIRT1054919	hsa-miR-770-5p	CLIP-seq
MIRT2244772	hsa-miR-1184	CLIP-seq
MIRT2244773	hsa-miR-1205	CLIP-seq
MIRT1054815	hsa-miR-1224-5p	CLIP-seq
MIRT2244774	hsa-miR-1278	CLIP-seq
MIRT2244775	hsa-miR-141	CLIP-seq
MIRT2244776	hsa-miR-146a	CLIP-seq
MIRT2244777	hsa-miR-146b-5p	CLIP-seq
MIRT1054825	hsa-miR-1827	CLIP-seq
MIRT2244778	hsa-miR-1909	CLIP-seq
MIRT2244779	hsa-miR-200a	CLIP-seq
MIRT2244780	hsa-miR-23a	CLIP-seq
MIRT2244781	hsa-miR-23b	CLIP-seq
MIRT2244782	hsa-miR-24	CLIP-seq
MIRT1054835	hsa-miR-3120-3p	CLIP-seq
MIRT2244783	hsa-miR-3120-5p	CLIP-seq
MIRT2244784	hsa-miR-3150b-3p	CLIP-seq
MIRT2244785	hsa-miR-3158-5p	CLIP-seq
MIRT1054838	hsa-miR-3164	CLIP-seq
MIRT2244786	hsa-miR-338-3p	CLIP-seq
MIRT2244787	hsa-miR-338-5p	CLIP-seq
MIRT2244788	hsa-miR-340	CLIP-seq
MIRT1054842	hsa-miR-34b	CLIP-seq
MIRT2244789	hsa-miR-3612	CLIP-seq
MIRT2244790	hsa-miR-3616-5p	CLIP-seq
MIRT2244791	hsa-miR-3647-5p	CLIP-seq
MIRT2244792	hsa-miR-3685	CLIP-seq
MIRT2244793	hsa-miR-384	CLIP-seq
MIRT1054850	hsa-miR-3915	CLIP-seq
MIRT2244794	hsa-miR-421	CLIP-seq
MIRT2244795	hsa-miR-4251	CLIP-seq
MIRT2244796	hsa-miR-4284	CLIP-seq
MIRT2244797	hsa-miR-4453	CLIP-seq
MIRT2244798	hsa-miR-4461	CLIP-seq
MIRT2244799	hsa-miR-4496	CLIP-seq
MIRT2244800	hsa-miR-4517	CLIP-seq
MIRT2244801	hsa-miR-4530	CLIP-seq
MIRT2244802	hsa-miR-4538	CLIP-seq
MIRT2244803	hsa-miR-4680-3p	CLIP-seq
MIRT1054878	hsa-miR-4689	CLIP-seq
MIRT2244804	hsa-miR-4693-5p	CLIP-seq
MIRT2244805	hsa-miR-4695-5p	CLIP-seq
MIRT1054887	hsa-miR-4735-5p	CLIP-seq
MIRT2244806	hsa-miR-4766-3p	CLIP-seq
MIRT1054892	hsa-miR-4778-5p	CLIP-seq
MIRT2244807	hsa-miR-4784	CLIP-seq
MIRT2244808	hsa-miR-487a	CLIP-seq
MIRT1054898	hsa-miR-494	CLIP-seq
MIRT2244809	hsa-miR-544	CLIP-seq
MIRT2244810	hsa-miR-548a-5p	CLIP-seq
MIRT1054905	hsa-miR-548aa	CLIP-seq
MIRT2244811	hsa-miR-548ab	CLIP-seq
MIRT2244812	hsa-miR-548ak	CLIP-seq
MIRT2244813	hsa-miR-548b-5p	CLIP-seq
MIRT2244814	hsa-miR-548c-5p	CLIP-seq
MIRT2244815	hsa-miR-548d-5p	CLIP-seq
MIRT2244816	hsa-miR-548h	CLIP-seq
MIRT2244817	hsa-miR-548i	CLIP-seq
MIRT2244818	hsa-miR-548j	CLIP-seq
MIRT2244819	hsa-miR-548k	CLIP-seq
MIRT2244820	hsa-miR-548p	CLIP-seq
MIRT2244821	hsa-miR-548w	CLIP-seq
MIRT2244822	hsa-miR-548y	CLIP-seq
MIRT2244823	hsa-miR-559	CLIP-seq
MIRT2244824	hsa-miR-573	CLIP-seq
MIRT1054910	hsa-miR-577	CLIP-seq
MIRT2244825	hsa-miR-589	CLIP-seq
MIRT2244826	hsa-miR-630	CLIP-seq
MIRT2244827	hsa-miR-650	CLIP-seq
MIRT2244828	hsa-miR-922	CLIP-seq
MIRT2244829	hsa-miR-940	CLIP-seq
MIRT2389186	hsa-miR-153	CLIP-seq
MIRT2244790	hsa-miR-3616-5p	CLIP-seq
MIRT2244791	hsa-miR-3647-5p	CLIP-seq
MIRT2389187	hsa-miR-448	CLIP-seq
MIRT1054908	hsa-miR-561	CLIP-seq
MIRT2244824	hsa-miR-573	CLIP-seq
MIRT2244829	hsa-miR-940	CLIP-seq
MIRT2244780	hsa-miR-23a	CLIP-seq
MIRT2244781	hsa-miR-23b	CLIP-seq
MIRT2451394	hsa-miR-3925-3p	CLIP-seq
MIRT1054858	hsa-miR-4264	CLIP-seq
MIRT2451395	hsa-miR-4717-3p	CLIP-seq
MIRT2451396	hsa-miR-4729	CLIP-seq
MIRT1054895	hsa-miR-4797-3p	CLIP-seq
MIRT2451397	hsa-miR-500a	CLIP-seq
MIRT2451398	hsa-miR-622	CLIP-seq
MIRT2451399	hsa-miR-766	CLIP-seq
MIRT2547720	hsa-miR-1202	CLIP-seq
MIRT1054815	hsa-miR-1224-5p	CLIP-seq
MIRT2547721	hsa-miR-1276	CLIP-seq
MIRT2547722	hsa-miR-1283	CLIP-seq
MIRT2547723	hsa-miR-1291	CLIP-seq
MIRT1054820	hsa-miR-129-5p	CLIP-seq
MIRT2547724	hsa-miR-1324	CLIP-seq
MIRT2547725	hsa-miR-133a	CLIP-seq
MIRT2547726	hsa-miR-133b	CLIP-seq
MIRT2244775	hsa-miR-141	CLIP-seq
MIRT2547727	hsa-miR-1587	CLIP-seq
MIRT1054825	hsa-miR-1827	CLIP-seq
MIRT2547728	hsa-miR-197	CLIP-seq
MIRT1054827	hsa-miR-198	CLIP-seq
MIRT2547729	hsa-miR-199a-3p	CLIP-seq
MIRT2547730	hsa-miR-199b-3p	CLIP-seq
MIRT2547731	hsa-miR-19a	CLIP-seq
MIRT2547732	hsa-miR-19b	CLIP-seq
MIRT2244779	hsa-miR-200a	CLIP-seq
MIRT2547733	hsa-miR-216a	CLIP-seq
MIRT2244780	hsa-miR-23a	CLIP-seq
MIRT2244781	hsa-miR-23b	CLIP-seq
MIRT2244782	hsa-miR-24	CLIP-seq
MIRT2547734	hsa-miR-298	CLIP-seq
MIRT2547735	hsa-miR-302a	CLIP-seq
MIRT2547736	hsa-miR-302b	CLIP-seq
MIRT2547737	hsa-miR-302c	CLIP-seq
MIRT2547738	hsa-miR-302d	CLIP-seq
MIRT2547739	hsa-miR-302e	CLIP-seq
MIRT2244783	hsa-miR-3120-5p	CLIP-seq
MIRT2547740	hsa-miR-3129-5p	CLIP-seq
MIRT2244784	hsa-miR-3150b-3p	CLIP-seq
MIRT2547741	hsa-miR-3163	CLIP-seq
MIRT2547742	hsa-miR-3176	CLIP-seq
MIRT2547743	hsa-miR-3194-5p	CLIP-seq
MIRT2547744	hsa-miR-326	CLIP-seq
MIRT2547745	hsa-miR-328	CLIP-seq
MIRT2547746	hsa-miR-330-5p	CLIP-seq
MIRT1920492	hsa-miR-3545-3p	CLIP-seq
MIRT2244789	hsa-miR-3612	CLIP-seq
MIRT2244790	hsa-miR-3616-5p	CLIP-seq
MIRT2244791	hsa-miR-3647-5p	CLIP-seq
MIRT2547747	hsa-miR-3662	CLIP-seq
MIRT2244792	hsa-miR-3685	CLIP-seq
MIRT2547748	hsa-miR-3692	CLIP-seq
MIRT1054847	hsa-miR-369-3p	CLIP-seq
MIRT2012485	hsa-miR-3714	CLIP-seq
MIRT2547749	hsa-miR-372	CLIP-seq
MIRT2547750	hsa-miR-373	CLIP-seq
MIRT2547751	hsa-miR-374a	CLIP-seq
MIRT2547752	hsa-miR-374b	CLIP-seq
MIRT2547753	hsa-miR-376c	CLIP-seq
MIRT2547754	hsa-miR-377	CLIP-seq
MIRT2244793	hsa-miR-384	CLIP-seq
MIRT1054850	hsa-miR-3915	CLIP-seq
MIRT2547755	hsa-miR-3922-3p	CLIP-seq
MIRT2547756	hsa-miR-3972	CLIP-seq
MIRT2012486	hsa-miR-3978	CLIP-seq
MIRT1054859	hsa-miR-4276	CLIP-seq
MIRT2547757	hsa-miR-4279	CLIP-seq
MIRT2547758	hsa-miR-4282	CLIP-seq
MIRT2244796	hsa-miR-4284	CLIP-seq
MIRT1054862	hsa-miR-4311	CLIP-seq
MIRT2547759	hsa-miR-4436b-5p	CLIP-seq
MIRT2244798	hsa-miR-4461	CLIP-seq
MIRT2547760	hsa-miR-4492	CLIP-seq
MIRT2012488	hsa-miR-4493	CLIP-seq
MIRT2547761	hsa-miR-4498	CLIP-seq
MIRT1549641	hsa-miR-4522	CLIP-seq
MIRT2547762	hsa-miR-4656	CLIP-seq
MIRT2547763	hsa-miR-4675	CLIP-seq
MIRT2547764	hsa-miR-4676-5p	CLIP-seq
MIRT1054878	hsa-miR-4689	CLIP-seq
MIRT2244804	hsa-miR-4693-5p	CLIP-seq
MIRT2547765	hsa-miR-4694-3p	CLIP-seq
MIRT2244805	hsa-miR-4695-5p	CLIP-seq
MIRT1054880	hsa-miR-4698	CLIP-seq
MIRT2547766	hsa-miR-4699-3p	CLIP-seq
MIRT1054882	hsa-miR-4712-5p	CLIP-seq
MIRT2547767	hsa-miR-4724-5p	CLIP-seq
MIRT1054887	hsa-miR-4735-5p	CLIP-seq
MIRT2547768	hsa-miR-4738-3p	CLIP-seq
MIRT2547769	hsa-miR-4741	CLIP-seq
MIRT2547770	hsa-miR-4744	CLIP-seq
MIRT2547771	hsa-miR-4760-3p	CLIP-seq
MIRT1054891	hsa-miR-4773	CLIP-seq
MIRT2244807	hsa-miR-4784	CLIP-seq
MIRT2547772	hsa-miR-4789-5p	CLIP-seq
MIRT2547773	hsa-miR-488	CLIP-seq
MIRT2547774	hsa-miR-492	CLIP-seq
MIRT2547775	hsa-miR-502-5p	CLIP-seq
MIRT2547776	hsa-miR-518a-5p	CLIP-seq
MIRT2547777	hsa-miR-519a	CLIP-seq
MIRT2547778	hsa-miR-519b-3p	CLIP-seq
MIRT2547779	hsa-miR-519c-3p	CLIP-seq
MIRT2547780	hsa-miR-520a-3p	CLIP-seq
MIRT2547781	hsa-miR-520b	CLIP-seq
MIRT2547782	hsa-miR-520c-3p	CLIP-seq
MIRT2547783	hsa-miR-520d-3p	CLIP-seq
MIRT2547784	hsa-miR-520e	CLIP-seq
MIRT2547785	hsa-miR-527	CLIP-seq
MIRT1054903	hsa-miR-539	CLIP-seq
MIRT2547786	hsa-miR-545	CLIP-seq
MIRT2547787	hsa-miR-548a-3p	CLIP-seq
MIRT1054905	hsa-miR-548aa	CLIP-seq
MIRT2547788	hsa-miR-548ae	CLIP-seq
MIRT2547789	hsa-miR-548aj	CLIP-seq
MIRT2547790	hsa-miR-548am	CLIP-seq
MIRT2547791	hsa-miR-548e	CLIP-seq
MIRT2547792	hsa-miR-548f	CLIP-seq
MIRT2547793	hsa-miR-548g	CLIP-seq
MIRT2547794	hsa-miR-548x	CLIP-seq
MIRT1054908	hsa-miR-561	CLIP-seq
MIRT2547795	hsa-miR-568	CLIP-seq
MIRT2244824	hsa-miR-573	CLIP-seq
MIRT2547796	hsa-miR-575	CLIP-seq
MIRT2547797	hsa-miR-583	CLIP-seq
MIRT2244827	hsa-miR-650	CLIP-seq
MIRT2547798	hsa-miR-762	CLIP-seq
MIRT1054919	hsa-miR-770-5p	CLIP-seq
MIRT2547799	hsa-miR-892a	CLIP-seq
MIRT2547800	hsa-miR-9	CLIP-seq
MIRT2547801	hsa-miR-936	CLIP-seq
MIRT2244829	hsa-miR-940	CLIP-seq
MIRT2547720	hsa-miR-1202	CLIP-seq
MIRT2547722	hsa-miR-1283	CLIP-seq
MIRT1054820	hsa-miR-129-5p	CLIP-seq
MIRT2682458	hsa-miR-1297	CLIP-seq
MIRT2547725	hsa-miR-133a	CLIP-seq
MIRT2547726	hsa-miR-133b	CLIP-seq
MIRT2389186	hsa-miR-153	CLIP-seq
MIRT1054827	hsa-miR-198	CLIP-seq
MIRT2547729	hsa-miR-199a-3p	CLIP-seq
MIRT2547730	hsa-miR-199b-3p	CLIP-seq
MIRT2547731	hsa-miR-19a	CLIP-seq
MIRT2547732	hsa-miR-19b	CLIP-seq
MIRT2682459	hsa-miR-26a	CLIP-seq
MIRT2682460	hsa-miR-26b	CLIP-seq
MIRT2547734	hsa-miR-298	CLIP-seq
MIRT2547735	hsa-miR-302a	CLIP-seq
MIRT2547736	hsa-miR-302b	CLIP-seq
MIRT2547737	hsa-miR-302c	CLIP-seq
MIRT2547738	hsa-miR-302d	CLIP-seq
MIRT2547739	hsa-miR-302e	CLIP-seq
MIRT2244783	hsa-miR-3120-5p	CLIP-seq
MIRT2547740	hsa-miR-3129-5p	CLIP-seq
MIRT2547741	hsa-miR-3163	CLIP-seq
MIRT2547743	hsa-miR-3194-5p	CLIP-seq
MIRT1920492	hsa-miR-3545-3p	CLIP-seq
MIRT1054845	hsa-miR-3646	CLIP-seq
MIRT2244792	hsa-miR-3685	CLIP-seq
MIRT2012485	hsa-miR-3714	CLIP-seq
MIRT2547749	hsa-miR-372	CLIP-seq
MIRT2547750	hsa-miR-373	CLIP-seq
MIRT2547754	hsa-miR-377	CLIP-seq
MIRT2244793	hsa-miR-384	CLIP-seq
MIRT2547756	hsa-miR-3972	CLIP-seq
MIRT2012486	hsa-miR-3978	CLIP-seq
MIRT2682461	hsa-miR-4261	CLIP-seq
MIRT1054859	hsa-miR-4276	CLIP-seq
MIRT2547758	hsa-miR-4282	CLIP-seq
MIRT2682462	hsa-miR-4465	CLIP-seq
MIRT2389187	hsa-miR-448	CLIP-seq
MIRT2012488	hsa-miR-4493	CLIP-seq
MIRT1549641	hsa-miR-4522	CLIP-seq
MIRT2547764	hsa-miR-4676-5p	CLIP-seq
MIRT2244804	hsa-miR-4693-5p	CLIP-seq
MIRT2547765	hsa-miR-4694-3p	CLIP-seq
MIRT1054880	hsa-miR-4698	CLIP-seq
MIRT2547766	hsa-miR-4699-3p	CLIP-seq
MIRT2547767	hsa-miR-4724-5p	CLIP-seq
MIRT1054887	hsa-miR-4735-5p	CLIP-seq
MIRT2547768	hsa-miR-4738-3p	CLIP-seq
MIRT2547773	hsa-miR-488	CLIP-seq
MIRT2547774	hsa-miR-492	CLIP-seq
MIRT2682463	hsa-miR-498	CLIP-seq
MIRT2547775	hsa-miR-502-5p	CLIP-seq
MIRT2547776	hsa-miR-518a-5p	CLIP-seq
MIRT2547777	hsa-miR-519a	CLIP-seq
MIRT2547778	hsa-miR-519b-3p	CLIP-seq
MIRT2547779	hsa-miR-519c-3p	CLIP-seq
MIRT2547780	hsa-miR-520a-3p	CLIP-seq
MIRT2547781	hsa-miR-520b	CLIP-seq
MIRT2547782	hsa-miR-520c-3p	CLIP-seq
MIRT2547783	hsa-miR-520d-3p	CLIP-seq
MIRT2547784	hsa-miR-520e	CLIP-seq
MIRT2682464	hsa-miR-522	CLIP-seq
MIRT2547785	hsa-miR-527	CLIP-seq
MIRT2547787	hsa-miR-548a-3p	CLIP-seq
MIRT1054905	hsa-miR-548aa	CLIP-seq
MIRT2547788	hsa-miR-548ae	CLIP-seq
MIRT2547789	hsa-miR-548aj	CLIP-seq
MIRT2547790	hsa-miR-548am	CLIP-seq
MIRT2547791	hsa-miR-548e	CLIP-seq
MIRT2547792	hsa-miR-548f	CLIP-seq
MIRT2547793	hsa-miR-548g	CLIP-seq
MIRT2547794	hsa-miR-548x	CLIP-seq
MIRT2547795	hsa-miR-568	CLIP-seq
MIRT2547796	hsa-miR-575	CLIP-seq
MIRT2547799	hsa-miR-892a	CLIP-seq
MIRT2547800	hsa-miR-9	CLIP-seq
MIRT2547801	hsa-miR-936	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0004394	Function	Heparan sulfate 2-sulfotransferase activity	IBA
GO:0004394	Function	Heparan sulfate 2-sulfotransferase activity	IEA
GO:0004394	Function	Heparan sulfate 2-sulfotransferase activity	ISS
GO:0004394	Function	Heparan sulfate 2-sulfotransferase activity	TAS
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0008146	Function	Sulfotransferase activity	IEA
GO:0010467	Process	Gene expression	IEA
GO:0015012	Process	Heparan sulfate proteoglycan biosynthetic process	IBA
GO:0015012	Process	Heparan sulfate proteoglycan biosynthetic process	IEA
GO:0015012	Process	Heparan sulfate proteoglycan biosynthetic process	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030202	Process	Heparin proteoglycan metabolic process	IEA
GO:0060676	Process	Ureteric bud formation	IEA

Other IDs

• MIM: 604844
• HGNC: 5193
• e!Ensembl: ENSG00000153936

Protein

• UniProt ID: Q7LGA3
• Protein name: Heparan sulfate 2-O-sulfotransferase 1 (EC 2.8.2.-) (2-O-sulfotransferase) (2-OST) (2OST) (HS 2-O-sulfotransferase) (Heparan sulfate 2-sulfotransferase)
• Protein function: Catalyzes the transfer of a sulfo group from 3'-phospho-5'-adenylyl sulfate (PAPS) to the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within the heparan sulfate (HS) chain and participates in HS biosynthesis (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03567	Sulfotransfer_2	66 → 327	Sulfotransferase family	Domain

• Sequence:

  MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMD
  GPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQD
  QVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFG
  DDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQA
  KYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQT
  IAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN

• Sequence length: 356

Pathways

KEGG:

Glycosaminoglycan biosynthesis - heparan sulfate / heparin

Reactome:

HS-GAG biosynthesis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Neurofacioskeletal syndrome with or without renal agenesis	Pathogenic	rs758990524, rs1660112720, rs1651973144	RCV001292560 RCV001292561 RCV001292562	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
NEUROFACIOSKELETAL SYNDROME WITHOUT RENAL AGENESIS	Pathogenic	rs1651459410, rs1651972168	RCV001292558 RCV001292559	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
DESBUQUOIS SYNDROME	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HS2ST1-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet, Orphanet Disgenet, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Agenesis of Corpus Callosum	Corpus callosum agenesis	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	32573871	Associate	★☆☆☆☆ Found in Text Mining only
Contracture	Contracture	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
Dry Eye Syndromes	Dry eye syndrome	Pubtator	19011014	Associate	★☆☆☆☆ Found in Text Mining only
Eosinophilia	Eosinophilia	BEFREE	29621420		★☆☆☆☆ Found in Text Mining only
Facial Dysmorphism with Multiple Malformations	Facial dysmorphism syndrome	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	29104277	Associate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	28107390		★☆☆☆☆ Found in Text Mining only
Orofaciodigital syndrome 3	Orofaciodigital syndrome	Pubtator	33159882	Associate	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	36387908	Associate	★☆☆☆☆ Found in Text Mining only