PTGES (prostaglandin E synthase)

Gene

• Entrez ID: 9536
• Gene name: Prostaglandin E synthase
• Gene symbol: PTGES
• Synonyms (NCBI Gene): MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1
• Chromosome: 9
• Chromosome location: 9q34.11
• Summary: The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor pr

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017384	hsa-miR-335-5p	Microarray	18185580
MIRT022404	hsa-miR-124-3p	Microarray	18668037
MIRT046064	hsa-miR-125b-5p	CLASH	23622248
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	24906430
MIRT488919	hsa-miR-4781-5p	PAR-CLIP	23592263
MIRT488920	hsa-miR-9500	PAR-CLIP	23592263
MIRT488918	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT488917	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT488916	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	27418678
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	27418678
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	27418678
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	27418678
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	27418678
MIRT608918	hsa-miR-8485	HITS-CLIP	27418678
MIRT608918	hsa-miR-8485	HITS-CLIP	27418678
MIRT608918	hsa-miR-8485	HITS-CLIP	27418678
MIRT608918	hsa-miR-8485	HITS-CLIP	27418678
MIRT608918	hsa-miR-8485	HITS-CLIP	27418678
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT608918	hsa-miR-8485	HITS-CLIP	23824327
MIRT611037	hsa-miR-2355-5p	HITS-CLIP	23824327
MIRT488919	hsa-miR-4781-5p	PAR-CLIP	23592263
MIRT488920	hsa-miR-9500	PAR-CLIP	23592263
MIRT488918	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT488917	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT488916	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT1272687	hsa-miR-103a	CLIP-seq
MIRT1272688	hsa-miR-107	CLIP-seq
MIRT1272689	hsa-miR-1184	CLIP-seq
MIRT1272690	hsa-miR-1252	CLIP-seq
MIRT1272691	hsa-miR-1253	CLIP-seq
MIRT1272692	hsa-miR-1266	CLIP-seq
MIRT1272693	hsa-miR-1290	CLIP-seq
MIRT1272694	hsa-miR-203	CLIP-seq
MIRT1272695	hsa-miR-3120-5p	CLIP-seq
MIRT1272696	hsa-miR-3122	CLIP-seq
MIRT1272697	hsa-miR-3126-5p	CLIP-seq
MIRT1272698	hsa-miR-3157-5p	CLIP-seq
MIRT1272699	hsa-miR-3166	CLIP-seq
MIRT1272700	hsa-miR-3189-3p	CLIP-seq
MIRT1272701	hsa-miR-3197	CLIP-seq
MIRT1272702	hsa-miR-3664-3p	CLIP-seq
MIRT1272703	hsa-miR-3689a-3p	CLIP-seq
MIRT1272704	hsa-miR-3689c	CLIP-seq
MIRT1272705	hsa-miR-371-5p	CLIP-seq
MIRT1272706	hsa-miR-377	CLIP-seq
MIRT1272707	hsa-miR-3913-5p	CLIP-seq
MIRT1272708	hsa-miR-3929	CLIP-seq
MIRT1272709	hsa-miR-412	CLIP-seq
MIRT1272710	hsa-miR-431	CLIP-seq
MIRT1272711	hsa-miR-4418	CLIP-seq
MIRT1272712	hsa-miR-4419b	CLIP-seq
MIRT1272713	hsa-miR-4433	CLIP-seq
MIRT1272714	hsa-miR-4443	CLIP-seq
MIRT1272715	hsa-miR-4459	CLIP-seq
MIRT1272716	hsa-miR-4478	CLIP-seq
MIRT1272717	hsa-miR-4518	CLIP-seq
MIRT1272718	hsa-miR-4635	CLIP-seq
MIRT1272719	hsa-miR-4649-3p	CLIP-seq
MIRT1272720	hsa-miR-4684-5p	CLIP-seq
MIRT1272721	hsa-miR-4691-3p	CLIP-seq
MIRT1272722	hsa-miR-4695-5p	CLIP-seq
MIRT1272723	hsa-miR-4728-5p	CLIP-seq
MIRT1272724	hsa-miR-4768-3p	CLIP-seq
MIRT1272725	hsa-miR-485-5p	CLIP-seq
MIRT1272726	hsa-miR-509-3-5p	CLIP-seq
MIRT1272727	hsa-miR-509-5p	CLIP-seq
MIRT1272728	hsa-miR-510	CLIP-seq
MIRT1272729	hsa-miR-512-5p	CLIP-seq
MIRT1272730	hsa-miR-513b	CLIP-seq
MIRT1272731	hsa-miR-522	CLIP-seq
MIRT1272732	hsa-miR-548c-3p	CLIP-seq
MIRT1272733	hsa-miR-570	CLIP-seq
MIRT1272734	hsa-miR-601	CLIP-seq
MIRT1272735	hsa-miR-888	CLIP-seq
MIRT1272736	hsa-miR-938	CLIP-seq
MIRT1272687	hsa-miR-103a	CLIP-seq
MIRT1272688	hsa-miR-107	CLIP-seq
MIRT1272689	hsa-miR-1184	CLIP-seq
MIRT1552677	hsa-miR-3617	CLIP-seq
MIRT1272711	hsa-miR-4418	CLIP-seq
MIRT1272726	hsa-miR-509-3-5p	CLIP-seq
MIRT1272727	hsa-miR-509-5p	CLIP-seq
MIRT1552678	hsa-miR-545	CLIP-seq
MIRT1552679	hsa-miR-641	CLIP-seq
MIRT1272692	hsa-miR-1266	CLIP-seq
MIRT2080186	hsa-miR-214	CLIP-seq
MIRT2080187	hsa-miR-3619-5p	CLIP-seq
MIRT2080188	hsa-miR-3939	CLIP-seq
MIRT1272713	hsa-miR-4433	CLIP-seq
MIRT2080189	hsa-miR-4496	CLIP-seq
MIRT1272717	hsa-miR-4518	CLIP-seq
MIRT2080190	hsa-miR-4690-5p	CLIP-seq
MIRT2080191	hsa-miR-4726-3p	CLIP-seq
MIRT2080192	hsa-miR-4755-3p	CLIP-seq
MIRT1272725	hsa-miR-485-5p	CLIP-seq
MIRT1272728	hsa-miR-510	CLIP-seq
MIRT1272732	hsa-miR-548c-3p	CLIP-seq
MIRT1272733	hsa-miR-570	CLIP-seq
MIRT2080193	hsa-miR-761	CLIP-seq
MIRT1272692	hsa-miR-1266	CLIP-seq
MIRT2306484	hsa-miR-1286	CLIP-seq
MIRT2306485	hsa-miR-329	CLIP-seq
MIRT2306486	hsa-miR-362-3p	CLIP-seq
MIRT1272702	hsa-miR-3664-3p	CLIP-seq
MIRT2306487	hsa-miR-3941	CLIP-seq
MIRT2306488	hsa-miR-4267	CLIP-seq
MIRT2306489	hsa-miR-4432	CLIP-seq
MIRT1272713	hsa-miR-4433	CLIP-seq
MIRT2306490	hsa-miR-4453	CLIP-seq
MIRT1272717	hsa-miR-4518	CLIP-seq
MIRT2306491	hsa-miR-451b	CLIP-seq
MIRT2306492	hsa-miR-4538	CLIP-seq
MIRT2306493	hsa-miR-4696	CLIP-seq
MIRT2306494	hsa-miR-4722-5p	CLIP-seq
MIRT2306495	hsa-miR-4789-3p	CLIP-seq
MIRT2306496	hsa-miR-483-3p	CLIP-seq
MIRT1272725	hsa-miR-485-5p	CLIP-seq
MIRT2306497	hsa-miR-494	CLIP-seq
MIRT2306498	hsa-miR-508-5p	CLIP-seq
MIRT1272728	hsa-miR-510	CLIP-seq
MIRT2306499	hsa-miR-517a	CLIP-seq
MIRT2306500	hsa-miR-517b	CLIP-seq
MIRT2306501	hsa-miR-517c	CLIP-seq
MIRT1272733	hsa-miR-570	CLIP-seq
MIRT2306502	hsa-miR-603	CLIP-seq
MIRT2306503	hsa-miR-635	CLIP-seq
MIRT2306504	hsa-miR-766	CLIP-seq
MIRT1272687	hsa-miR-103a	CLIP-seq
MIRT1272688	hsa-miR-107	CLIP-seq
MIRT1272689	hsa-miR-1184	CLIP-seq
MIRT2439652	hsa-miR-1224-3p	CLIP-seq
MIRT2439653	hsa-miR-1228	CLIP-seq
MIRT1272690	hsa-miR-1252	CLIP-seq
MIRT1272691	hsa-miR-1253	CLIP-seq
MIRT2439654	hsa-miR-1260	CLIP-seq
MIRT2439655	hsa-miR-1260b	CLIP-seq
MIRT1272692	hsa-miR-1266	CLIP-seq
MIRT2439656	hsa-miR-1280	CLIP-seq
MIRT2439657	hsa-miR-1299	CLIP-seq
MIRT2439658	hsa-miR-1914	CLIP-seq
MIRT2080186	hsa-miR-214	CLIP-seq
MIRT2439659	hsa-miR-296-5p	CLIP-seq
MIRT2439660	hsa-miR-3127-5p	CLIP-seq
MIRT2439661	hsa-miR-3150b-3p	CLIP-seq
MIRT1272700	hsa-miR-3189-3p	CLIP-seq
MIRT2439662	hsa-miR-3202	CLIP-seq
MIRT2080187	hsa-miR-3619-5p	CLIP-seq
MIRT2439663	hsa-miR-3622a-3p	CLIP-seq
MIRT2439664	hsa-miR-3622b-3p	CLIP-seq
MIRT2439665	hsa-miR-3651	CLIP-seq
MIRT1272703	hsa-miR-3689a-3p	CLIP-seq
MIRT1272704	hsa-miR-3689c	CLIP-seq
MIRT2439666	hsa-miR-3918	CLIP-seq
MIRT1272708	hsa-miR-3929	CLIP-seq
MIRT2080188	hsa-miR-3939	CLIP-seq
MIRT2439667	hsa-miR-4265	CLIP-seq
MIRT2439668	hsa-miR-4296	CLIP-seq
MIRT2439669	hsa-miR-4322	CLIP-seq
MIRT2439670	hsa-miR-4417	CLIP-seq
MIRT1272711	hsa-miR-4418	CLIP-seq
MIRT1272712	hsa-miR-4419b	CLIP-seq
MIRT2439671	hsa-miR-4434	CLIP-seq
MIRT1272716	hsa-miR-4478	CLIP-seq
MIRT2080189	hsa-miR-4496	CLIP-seq
MIRT2439672	hsa-miR-4516	CLIP-seq
MIRT1272717	hsa-miR-4518	CLIP-seq
MIRT2439673	hsa-miR-4533	CLIP-seq
MIRT2439674	hsa-miR-4663	CLIP-seq
MIRT2080190	hsa-miR-4690-5p	CLIP-seq
MIRT2080191	hsa-miR-4726-3p	CLIP-seq
MIRT1272723	hsa-miR-4728-5p	CLIP-seq
MIRT2439675	hsa-miR-4749-3p	CLIP-seq
MIRT2080192	hsa-miR-4755-3p	CLIP-seq
MIRT2439676	hsa-miR-4784	CLIP-seq
MIRT1272726	hsa-miR-509-3-5p	CLIP-seq
MIRT1272727	hsa-miR-509-5p	CLIP-seq
MIRT1272728	hsa-miR-510	CLIP-seq
MIRT2439677	hsa-miR-516a-3p	CLIP-seq
MIRT2439678	hsa-miR-532-3p	CLIP-seq
MIRT2080193	hsa-miR-761	CLIP-seq
MIRT2439679	hsa-miR-765	CLIP-seq
MIRT2439680	hsa-miR-875-3p	CLIP-seq
MIRT2306484	hsa-miR-1286	CLIP-seq
MIRT1272696	hsa-miR-3122	CLIP-seq
MIRT1272701	hsa-miR-3197	CLIP-seq
MIRT1272703	hsa-miR-3689a-3p	CLIP-seq
MIRT1272704	hsa-miR-3689c	CLIP-seq
MIRT1272707	hsa-miR-3913-5p	CLIP-seq
MIRT2457403	hsa-miR-4489	CLIP-seq
MIRT2306494	hsa-miR-4722-5p	CLIP-seq
MIRT1272723	hsa-miR-4728-5p	CLIP-seq
MIRT1272687	hsa-miR-103a	CLIP-seq
MIRT1272688	hsa-miR-107	CLIP-seq
MIRT1272689	hsa-miR-1184	CLIP-seq
MIRT2603733	hsa-miR-1207-3p	CLIP-seq
MIRT2603734	hsa-miR-1207-5p	CLIP-seq
MIRT2439652	hsa-miR-1224-3p	CLIP-seq
MIRT2439653	hsa-miR-1228	CLIP-seq
MIRT1272690	hsa-miR-1252	CLIP-seq
MIRT1272691	hsa-miR-1253	CLIP-seq
MIRT2439654	hsa-miR-1260	CLIP-seq
MIRT2439655	hsa-miR-1260b	CLIP-seq
MIRT1272692	hsa-miR-1266	CLIP-seq
MIRT2603735	hsa-miR-128	CLIP-seq
MIRT2439656	hsa-miR-1280	CLIP-seq
MIRT2603736	hsa-miR-1285	CLIP-seq
MIRT2306484	hsa-miR-1286	CLIP-seq
MIRT1272693	hsa-miR-1290	CLIP-seq
MIRT2439657	hsa-miR-1299	CLIP-seq
MIRT2603737	hsa-miR-1304	CLIP-seq
MIRT2603738	hsa-miR-1343	CLIP-seq
MIRT2603739	hsa-miR-146a	CLIP-seq
MIRT2603740	hsa-miR-146b-3p	CLIP-seq
MIRT2603741	hsa-miR-146b-5p	CLIP-seq
MIRT2603742	hsa-miR-1909	CLIP-seq
MIRT2439658	hsa-miR-1914	CLIP-seq
MIRT2603743	hsa-miR-2115	CLIP-seq
MIRT2080186	hsa-miR-214	CLIP-seq
MIRT2603744	hsa-miR-24	CLIP-seq
MIRT2439659	hsa-miR-296-5p	CLIP-seq
MIRT1272695	hsa-miR-3120-5p	CLIP-seq
MIRT2603745	hsa-miR-3121-5p	CLIP-seq
MIRT1272696	hsa-miR-3122	CLIP-seq
MIRT1272697	hsa-miR-3126-5p	CLIP-seq
MIRT2439660	hsa-miR-3127-5p	CLIP-seq
MIRT2603746	hsa-miR-3136-3p	CLIP-seq
MIRT2603747	hsa-miR-3148	CLIP-seq
MIRT2439661	hsa-miR-3150b-3p	CLIP-seq
MIRT2603748	hsa-miR-3165	CLIP-seq
MIRT2603749	hsa-miR-3173-3p	CLIP-seq
MIRT2603750	hsa-miR-3176	CLIP-seq
MIRT2603751	hsa-miR-3179	CLIP-seq
MIRT2603752	hsa-miR-3187-3p	CLIP-seq
MIRT2603753	hsa-miR-3187-5p	CLIP-seq
MIRT1272700	hsa-miR-3189-3p	CLIP-seq
MIRT2603754	hsa-miR-3194-5p	CLIP-seq
MIRT1272701	hsa-miR-3197	CLIP-seq
MIRT2439662	hsa-miR-3202	CLIP-seq
MIRT2603755	hsa-miR-328	CLIP-seq
MIRT2306485	hsa-miR-329	CLIP-seq
MIRT2603756	hsa-miR-331-3p	CLIP-seq
MIRT2603757	hsa-miR-339-5p	CLIP-seq
MIRT2603758	hsa-miR-3612	CLIP-seq
MIRT2603759	hsa-miR-3614-5p	CLIP-seq
MIRT1552677	hsa-miR-3617	CLIP-seq
MIRT2080187	hsa-miR-3619-5p	CLIP-seq
MIRT2439663	hsa-miR-3622a-3p	CLIP-seq
MIRT2439664	hsa-miR-3622b-3p	CLIP-seq
MIRT2306486	hsa-miR-362-3p	CLIP-seq
MIRT2439665	hsa-miR-3651	CLIP-seq
MIRT2603760	hsa-miR-3652	CLIP-seq
MIRT2603761	hsa-miR-3663-3p	CLIP-seq
MIRT1272702	hsa-miR-3664-3p	CLIP-seq
MIRT2603762	hsa-miR-3664-5p	CLIP-seq
MIRT2603763	hsa-miR-3667-5p	CLIP-seq
MIRT1272703	hsa-miR-3689a-3p	CLIP-seq
MIRT1272704	hsa-miR-3689c	CLIP-seq
MIRT2603764	hsa-miR-3692	CLIP-seq
MIRT1272705	hsa-miR-371-5p	CLIP-seq
MIRT1272706	hsa-miR-377	CLIP-seq
MIRT1272707	hsa-miR-3913-5p	CLIP-seq
MIRT2603765	hsa-miR-3914	CLIP-seq
MIRT2439666	hsa-miR-3918	CLIP-seq
MIRT2603766	hsa-miR-3919	CLIP-seq
MIRT2603767	hsa-miR-3922-3p	CLIP-seq
MIRT2603768	hsa-miR-3925-5p	CLIP-seq
MIRT2603769	hsa-miR-3926	CLIP-seq
MIRT1272708	hsa-miR-3929	CLIP-seq
MIRT2080188	hsa-miR-3939	CLIP-seq
MIRT2306487	hsa-miR-3941	CLIP-seq
MIRT2603770	hsa-miR-3977	CLIP-seq
MIRT2603771	hsa-miR-3978	CLIP-seq
MIRT1272709	hsa-miR-412	CLIP-seq
MIRT2439667	hsa-miR-4265	CLIP-seq
MIRT2306488	hsa-miR-4267	CLIP-seq
MIRT2603772	hsa-miR-4284	CLIP-seq
MIRT2439668	hsa-miR-4296	CLIP-seq
MIRT2603773	hsa-miR-4299	CLIP-seq
MIRT2603774	hsa-miR-4300	CLIP-seq
MIRT1272710	hsa-miR-431	CLIP-seq
MIRT2603775	hsa-miR-432	CLIP-seq
MIRT2439669	hsa-miR-4322	CLIP-seq
MIRT2439670	hsa-miR-4417	CLIP-seq
MIRT1272711	hsa-miR-4418	CLIP-seq
MIRT1272712	hsa-miR-4419b	CLIP-seq
MIRT2603776	hsa-miR-4430	CLIP-seq
MIRT2306489	hsa-miR-4432	CLIP-seq
MIRT1272713	hsa-miR-4433	CLIP-seq
MIRT2439671	hsa-miR-4434	CLIP-seq
MIRT1272714	hsa-miR-4443	CLIP-seq
MIRT2306490	hsa-miR-4453	CLIP-seq
MIRT2603777	hsa-miR-4456	CLIP-seq
MIRT1272715	hsa-miR-4459	CLIP-seq
MIRT2603778	hsa-miR-4475	CLIP-seq
MIRT1272716	hsa-miR-4478	CLIP-seq
MIRT2603779	hsa-miR-4481	CLIP-seq
MIRT2457403	hsa-miR-4489	CLIP-seq
MIRT2080189	hsa-miR-4496	CLIP-seq
MIRT2603780	hsa-miR-4505	CLIP-seq
MIRT2439672	hsa-miR-4516	CLIP-seq
MIRT1272717	hsa-miR-4518	CLIP-seq
MIRT2306491	hsa-miR-451b	CLIP-seq
MIRT2603781	hsa-miR-4522	CLIP-seq
MIRT2603782	hsa-miR-4527	CLIP-seq
MIRT2603783	hsa-miR-4529-5p	CLIP-seq
MIRT2439673	hsa-miR-4533	CLIP-seq
MIRT2306492	hsa-miR-4538	CLIP-seq
MIRT1272718	hsa-miR-4635	CLIP-seq
MIRT2603784	hsa-miR-4641	CLIP-seq
MIRT1272719	hsa-miR-4649-3p	CLIP-seq
MIRT2603785	hsa-miR-4658	CLIP-seq
MIRT2439674	hsa-miR-4663	CLIP-seq
MIRT2603786	hsa-miR-4667-3p	CLIP-seq
MIRT1272720	hsa-miR-4684-5p	CLIP-seq
MIRT2080190	hsa-miR-4690-5p	CLIP-seq
MIRT2603787	hsa-miR-4691-5p	CLIP-seq
MIRT1272722	hsa-miR-4695-5p	CLIP-seq
MIRT2306493	hsa-miR-4696	CLIP-seq
MIRT2603788	hsa-miR-4699-5p	CLIP-seq
MIRT2603789	hsa-miR-4700-3p	CLIP-seq
MIRT2603790	hsa-miR-4709-3p	CLIP-seq
MIRT2603791	hsa-miR-4711-5p	CLIP-seq
MIRT2603792	hsa-miR-4717-3p	CLIP-seq
MIRT2306494	hsa-miR-4722-5p	CLIP-seq
MIRT2603793	hsa-miR-4724-5p	CLIP-seq
MIRT2080191	hsa-miR-4726-3p	CLIP-seq
MIRT1272723	hsa-miR-4728-5p	CLIP-seq
MIRT2603794	hsa-miR-4736	CLIP-seq
MIRT2603795	hsa-miR-4745-5p	CLIP-seq
MIRT2439675	hsa-miR-4749-3p	CLIP-seq
MIRT2080192	hsa-miR-4755-3p	CLIP-seq
MIRT2603796	hsa-miR-4758-5p	CLIP-seq
MIRT2603797	hsa-miR-4763-3p	CLIP-seq
MIRT1272724	hsa-miR-4768-3p	CLIP-seq
MIRT2603798	hsa-miR-4783-3p	CLIP-seq
MIRT2439676	hsa-miR-4784	CLIP-seq
MIRT2306495	hsa-miR-4789-3p	CLIP-seq
MIRT2306496	hsa-miR-483-3p	CLIP-seq
MIRT1272725	hsa-miR-485-5p	CLIP-seq
MIRT2306497	hsa-miR-494	CLIP-seq
MIRT2603799	hsa-miR-508-3p	CLIP-seq
MIRT2306498	hsa-miR-508-5p	CLIP-seq
MIRT1272726	hsa-miR-509-3-5p	CLIP-seq
MIRT1272727	hsa-miR-509-5p	CLIP-seq
MIRT1272728	hsa-miR-510	CLIP-seq
MIRT1272729	hsa-miR-512-5p	CLIP-seq
MIRT2603800	hsa-miR-513a-5p	CLIP-seq
MIRT1272730	hsa-miR-513b	CLIP-seq
MIRT2439677	hsa-miR-516a-3p	CLIP-seq
MIRT2306499	hsa-miR-517a	CLIP-seq
MIRT2306500	hsa-miR-517b	CLIP-seq
MIRT2306501	hsa-miR-517c	CLIP-seq
MIRT2439678	hsa-miR-532-3p	CLIP-seq
MIRT1552678	hsa-miR-545	CLIP-seq
MIRT2603801	hsa-miR-548a-3p	CLIP-seq
MIRT2603802	hsa-miR-548al	CLIP-seq
MIRT1272732	hsa-miR-548c-3p	CLIP-seq
MIRT2603803	hsa-miR-548e	CLIP-seq
MIRT2603804	hsa-miR-548f	CLIP-seq
MIRT2603805	hsa-miR-548q	CLIP-seq
MIRT2603806	hsa-miR-548s	CLIP-seq
MIRT1272733	hsa-miR-570	CLIP-seq
MIRT1272734	hsa-miR-601	CLIP-seq
MIRT2603807	hsa-miR-602	CLIP-seq
MIRT2306502	hsa-miR-603	CLIP-seq
MIRT2603808	hsa-miR-612	CLIP-seq
MIRT2603809	hsa-miR-615-5p	CLIP-seq
MIRT2306503	hsa-miR-635	CLIP-seq
MIRT1552679	hsa-miR-641	CLIP-seq
MIRT2603810	hsa-miR-650	CLIP-seq
MIRT2603811	hsa-miR-658	CLIP-seq
MIRT2603812	hsa-miR-665	CLIP-seq
MIRT2080193	hsa-miR-761	CLIP-seq
MIRT2439679	hsa-miR-765	CLIP-seq
MIRT2306504	hsa-miR-766	CLIP-seq
MIRT2603813	hsa-miR-873	CLIP-seq
MIRT2439680	hsa-miR-875-3p	CLIP-seq
MIRT1272735	hsa-miR-888	CLIP-seq
MIRT2603814	hsa-miR-920	CLIP-seq
MIRT1272736	hsa-miR-938	CLIP-seq
MIRT1272687	hsa-miR-103a	CLIP-seq
MIRT1272688	hsa-miR-107	CLIP-seq
MIRT1272689	hsa-miR-1184	CLIP-seq
MIRT2603733	hsa-miR-1207-3p	CLIP-seq
MIRT2603734	hsa-miR-1207-5p	CLIP-seq
MIRT2688903	hsa-miR-1208	CLIP-seq
MIRT2439652	hsa-miR-1224-3p	CLIP-seq
MIRT2439653	hsa-miR-1228	CLIP-seq
MIRT1272690	hsa-miR-1252	CLIP-seq
MIRT1272691	hsa-miR-1253	CLIP-seq
MIRT2688904	hsa-miR-1258	CLIP-seq
MIRT2439654	hsa-miR-1260	CLIP-seq
MIRT2439655	hsa-miR-1260b	CLIP-seq
MIRT1272692	hsa-miR-1266	CLIP-seq
MIRT2603735	hsa-miR-128	CLIP-seq
MIRT2439656	hsa-miR-1280	CLIP-seq
MIRT2603736	hsa-miR-1285	CLIP-seq
MIRT2306484	hsa-miR-1286	CLIP-seq
MIRT1272693	hsa-miR-1290	CLIP-seq
MIRT2439657	hsa-miR-1299	CLIP-seq
MIRT2603737	hsa-miR-1304	CLIP-seq
MIRT2688905	hsa-miR-1321	CLIP-seq
MIRT2603738	hsa-miR-1343	CLIP-seq
MIRT2603740	hsa-miR-146b-3p	CLIP-seq
MIRT2603742	hsa-miR-1909	CLIP-seq
MIRT2439658	hsa-miR-1914	CLIP-seq
MIRT2603743	hsa-miR-2115	CLIP-seq
MIRT2080186	hsa-miR-214	CLIP-seq
MIRT2603744	hsa-miR-24	CLIP-seq
MIRT2439659	hsa-miR-296-5p	CLIP-seq
MIRT1272695	hsa-miR-3120-5p	CLIP-seq
MIRT2603745	hsa-miR-3121-5p	CLIP-seq
MIRT1272696	hsa-miR-3122	CLIP-seq
MIRT1272697	hsa-miR-3126-5p	CLIP-seq
MIRT2439660	hsa-miR-3127-5p	CLIP-seq
MIRT2603746	hsa-miR-3136-3p	CLIP-seq
MIRT2603747	hsa-miR-3148	CLIP-seq
MIRT2439661	hsa-miR-3150b-3p	CLIP-seq
MIRT2688906	hsa-miR-3162-5p	CLIP-seq
MIRT2603748	hsa-miR-3165	CLIP-seq
MIRT2603749	hsa-miR-3173-3p	CLIP-seq
MIRT2603750	hsa-miR-3176	CLIP-seq
MIRT2603751	hsa-miR-3179	CLIP-seq
MIRT2603752	hsa-miR-3187-3p	CLIP-seq
MIRT2603753	hsa-miR-3187-5p	CLIP-seq
MIRT1272700	hsa-miR-3189-3p	CLIP-seq
MIRT2688907	hsa-miR-3194-3p	CLIP-seq
MIRT2603754	hsa-miR-3194-5p	CLIP-seq
MIRT1272701	hsa-miR-3197	CLIP-seq
MIRT2439662	hsa-miR-3202	CLIP-seq
MIRT2603755	hsa-miR-328	CLIP-seq
MIRT2306485	hsa-miR-329	CLIP-seq
MIRT2603756	hsa-miR-331-3p	CLIP-seq
MIRT2603757	hsa-miR-339-5p	CLIP-seq
MIRT2603758	hsa-miR-3612	CLIP-seq
MIRT2603759	hsa-miR-3614-5p	CLIP-seq
MIRT1552677	hsa-miR-3617	CLIP-seq
MIRT2080187	hsa-miR-3619-5p	CLIP-seq
MIRT2439663	hsa-miR-3622a-3p	CLIP-seq
MIRT2439664	hsa-miR-3622b-3p	CLIP-seq
MIRT2306486	hsa-miR-362-3p	CLIP-seq
MIRT2439665	hsa-miR-3651	CLIP-seq
MIRT2603760	hsa-miR-3652	CLIP-seq
MIRT2603761	hsa-miR-3663-3p	CLIP-seq
MIRT1272702	hsa-miR-3664-3p	CLIP-seq
MIRT2603762	hsa-miR-3664-5p	CLIP-seq
MIRT2603763	hsa-miR-3667-5p	CLIP-seq
MIRT1272703	hsa-miR-3689a-3p	CLIP-seq
MIRT1272704	hsa-miR-3689c	CLIP-seq
MIRT1272705	hsa-miR-371-5p	CLIP-seq
MIRT1272706	hsa-miR-377	CLIP-seq
MIRT1272707	hsa-miR-3913-5p	CLIP-seq
MIRT2603765	hsa-miR-3914	CLIP-seq
MIRT2439666	hsa-miR-3918	CLIP-seq
MIRT2603767	hsa-miR-3922-3p	CLIP-seq
MIRT2603769	hsa-miR-3926	CLIP-seq
MIRT1272708	hsa-miR-3929	CLIP-seq
MIRT2080188	hsa-miR-3939	CLIP-seq
MIRT2306487	hsa-miR-3941	CLIP-seq
MIRT2603770	hsa-miR-3977	CLIP-seq
MIRT2603771	hsa-miR-3978	CLIP-seq
MIRT2439667	hsa-miR-4265	CLIP-seq
MIRT2306488	hsa-miR-4267	CLIP-seq
MIRT2603772	hsa-miR-4284	CLIP-seq
MIRT2688908	hsa-miR-4287	CLIP-seq
MIRT2439668	hsa-miR-4296	CLIP-seq
MIRT2603773	hsa-miR-4299	CLIP-seq
MIRT2603774	hsa-miR-4300	CLIP-seq
MIRT2688909	hsa-miR-4307	CLIP-seq
MIRT1272710	hsa-miR-431	CLIP-seq
MIRT2603775	hsa-miR-432	CLIP-seq
MIRT2439669	hsa-miR-4322	CLIP-seq
MIRT2439670	hsa-miR-4417	CLIP-seq
MIRT1272711	hsa-miR-4418	CLIP-seq
MIRT2688910	hsa-miR-4419a	CLIP-seq
MIRT1272712	hsa-miR-4419b	CLIP-seq
MIRT2688911	hsa-miR-4420	CLIP-seq
MIRT2603776	hsa-miR-4430	CLIP-seq
MIRT2306489	hsa-miR-4432	CLIP-seq
MIRT1272713	hsa-miR-4433	CLIP-seq
MIRT2439671	hsa-miR-4434	CLIP-seq
MIRT1272714	hsa-miR-4443	CLIP-seq
MIRT2306490	hsa-miR-4453	CLIP-seq
MIRT2603777	hsa-miR-4456	CLIP-seq
MIRT1272715	hsa-miR-4459	CLIP-seq
MIRT2688912	hsa-miR-4469	CLIP-seq
MIRT2603778	hsa-miR-4475	CLIP-seq
MIRT1272716	hsa-miR-4478	CLIP-seq
MIRT2603779	hsa-miR-4481	CLIP-seq
MIRT2457403	hsa-miR-4489	CLIP-seq
MIRT2080189	hsa-miR-4496	CLIP-seq
MIRT2603780	hsa-miR-4505	CLIP-seq
MIRT2688913	hsa-miR-4510	CLIP-seq
MIRT2439672	hsa-miR-4516	CLIP-seq
MIRT1272717	hsa-miR-4518	CLIP-seq
MIRT2306491	hsa-miR-451b	CLIP-seq
MIRT2603781	hsa-miR-4522	CLIP-seq
MIRT2603782	hsa-miR-4527	CLIP-seq
MIRT2603783	hsa-miR-4529-5p	CLIP-seq
MIRT2439673	hsa-miR-4533	CLIP-seq
MIRT2306492	hsa-miR-4538	CLIP-seq
MIRT1272718	hsa-miR-4635	CLIP-seq
MIRT2603784	hsa-miR-4641	CLIP-seq
MIRT1272719	hsa-miR-4649-3p	CLIP-seq
MIRT2603785	hsa-miR-4658	CLIP-seq
MIRT2439674	hsa-miR-4663	CLIP-seq
MIRT2603786	hsa-miR-4667-3p	CLIP-seq
MIRT1272720	hsa-miR-4684-5p	CLIP-seq
MIRT2688914	hsa-miR-4685-3p	CLIP-seq
MIRT2080190	hsa-miR-4690-5p	CLIP-seq
MIRT2603787	hsa-miR-4691-5p	CLIP-seq
MIRT1272722	hsa-miR-4695-5p	CLIP-seq
MIRT2306493	hsa-miR-4696	CLIP-seq
MIRT2603788	hsa-miR-4699-5p	CLIP-seq
MIRT2603789	hsa-miR-4700-3p	CLIP-seq
MIRT2603790	hsa-miR-4709-3p	CLIP-seq
MIRT2603791	hsa-miR-4711-5p	CLIP-seq
MIRT2603792	hsa-miR-4717-3p	CLIP-seq
MIRT2306494	hsa-miR-4722-5p	CLIP-seq
MIRT2603793	hsa-miR-4724-5p	CLIP-seq
MIRT2080191	hsa-miR-4726-3p	CLIP-seq
MIRT1272723	hsa-miR-4728-5p	CLIP-seq
MIRT2603794	hsa-miR-4736	CLIP-seq
MIRT2688915	hsa-miR-4739	CLIP-seq
MIRT2603795	hsa-miR-4745-5p	CLIP-seq
MIRT2439675	hsa-miR-4749-3p	CLIP-seq
MIRT2688916	hsa-miR-4753-3p	CLIP-seq
MIRT2080192	hsa-miR-4755-3p	CLIP-seq
MIRT2688917	hsa-miR-4756-5p	CLIP-seq
MIRT2603796	hsa-miR-4758-5p	CLIP-seq
MIRT2603797	hsa-miR-4763-3p	CLIP-seq
MIRT2688918	hsa-miR-4765	CLIP-seq
MIRT1272724	hsa-miR-4768-3p	CLIP-seq
MIRT2688919	hsa-miR-4768-5p	CLIP-seq
MIRT2603798	hsa-miR-4783-3p	CLIP-seq
MIRT2439676	hsa-miR-4784	CLIP-seq
MIRT2306495	hsa-miR-4789-3p	CLIP-seq
MIRT2306496	hsa-miR-483-3p	CLIP-seq
MIRT1272725	hsa-miR-485-5p	CLIP-seq
MIRT2306497	hsa-miR-494	CLIP-seq
MIRT2603799	hsa-miR-508-3p	CLIP-seq
MIRT2306498	hsa-miR-508-5p	CLIP-seq
MIRT1272726	hsa-miR-509-3-5p	CLIP-seq
MIRT1272727	hsa-miR-509-5p	CLIP-seq
MIRT2688920	hsa-miR-5096	CLIP-seq
MIRT1272728	hsa-miR-510	CLIP-seq
MIRT1272729	hsa-miR-512-5p	CLIP-seq
MIRT2603800	hsa-miR-513a-5p	CLIP-seq
MIRT2439677	hsa-miR-516a-3p	CLIP-seq
MIRT2306499	hsa-miR-517a	CLIP-seq
MIRT2306500	hsa-miR-517b	CLIP-seq
MIRT2306501	hsa-miR-517c	CLIP-seq
MIRT2439678	hsa-miR-532-3p	CLIP-seq
MIRT1552678	hsa-miR-545	CLIP-seq
MIRT2603801	hsa-miR-548a-3p	CLIP-seq
MIRT2603802	hsa-miR-548al	CLIP-seq
MIRT1272732	hsa-miR-548c-3p	CLIP-seq
MIRT2603803	hsa-miR-548e	CLIP-seq
MIRT2603804	hsa-miR-548f	CLIP-seq
MIRT2603805	hsa-miR-548q	CLIP-seq
MIRT2603806	hsa-miR-548s	CLIP-seq
MIRT1272733	hsa-miR-570	CLIP-seq
MIRT1272734	hsa-miR-601	CLIP-seq
MIRT2603807	hsa-miR-602	CLIP-seq
MIRT2306502	hsa-miR-603	CLIP-seq
MIRT2603808	hsa-miR-612	CLIP-seq
MIRT2603809	hsa-miR-615-5p	CLIP-seq
MIRT2306503	hsa-miR-635	CLIP-seq
MIRT1552679	hsa-miR-641	CLIP-seq
MIRT2603810	hsa-miR-650	CLIP-seq
MIRT2603811	hsa-miR-658	CLIP-seq
MIRT2603812	hsa-miR-665	CLIP-seq
MIRT2080193	hsa-miR-761	CLIP-seq
MIRT2439679	hsa-miR-765	CLIP-seq
MIRT2306504	hsa-miR-766	CLIP-seq
MIRT2603813	hsa-miR-873	CLIP-seq
MIRT2439680	hsa-miR-875-3p	CLIP-seq
MIRT1272735	hsa-miR-888	CLIP-seq
MIRT2603814	hsa-miR-920	CLIP-seq
MIRT1272736	hsa-miR-938	CLIP-seq
MIRT2688921	hsa-miR-942	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
CREB1	Unknown	20688046
EGR1	Activation	21983014
HDAC4	Unknown	19115247
HIF1A	Activation	18050215
NFKB1	Activation	17928629
RELA	Activation	17928629
SP1	Unknown	20688046

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001516	Process	Prostaglandin biosynthetic process	IBA
GO:0001516	Process	Prostaglandin biosynthetic process	IDA	18682561
GO:0001516	Process	Prostaglandin biosynthetic process	IEA
GO:0004364	Function	Glutathione transferase activity	IDA	12672824
GO:0004364	Function	Glutathione transferase activity	IEA
GO:0004602	Function	Glutathione peroxidase activity	IDA	12244105
GO:0004602	Function	Glutathione peroxidase activity	IEA
GO:0004667	Function	Prostaglandin-D synthase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005641	Component	Nuclear envelope lumen	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0006693	Process	Prostaglandin metabolic process	IEA
GO:0006693	Process	Prostaglandin metabolic process	IEA
GO:0006693	Process	Prostaglandin metabolic process	TAS	10377395
GO:0007165	Process	Signal transduction	NAS	10377395
GO:0008283	Process	Cell population proliferation	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IDA	18682561
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	10377395
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016853	Function	Isomerase activity	IEA
GO:0019233	Process	Sensory perception of pain	IEA
GO:0019233	Process	Sensory perception of pain	ISS
GO:0031620	Process	Regulation of fever generation	IEA
GO:0031620	Process	Regulation of fever generation	ISS
GO:0032308	Process	Positive regulation of prostaglandin secretion	IEA
GO:0043295	Function	Glutathione binding	IDA	18682561
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050220	Function	Prostaglandin-E synthase activity	IBA
GO:0050220	Function	Prostaglandin-E synthase activity	IDA	18682561
GO:0050220	Function	Prostaglandin-E synthase activity	IEA
GO:0050727	Process	Regulation of inflammatory response	IEA
GO:0050727	Process	Regulation of inflammatory response	ISS
GO:0098869	Process	Cellular oxidant detoxification	IEA

Other IDs

• MIM: 605172
• HGNC: 9599
• e!Ensembl: ENSG00000148344

Protein

• UniProt ID: O14684
• Protein name: Prostaglandin E synthase (EC 5.3.99.3) (Glutathione peroxidase PTGES) (EC 1.11.1.-) (Glutathione transferase PTGES) (EC 2.5.1.18) (Microsomal glutathione S-transferase 1-like 1) (MGST1-L1) (Microsomal prostaglandin E synthase 1) (MPGES-1) (p53-induced gen
• Protein function: Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammator
• PDB: 3DWW, 4AL0, 4AL1, 4BPM, 4WAB, 4YK5, 4YL0, 4YL1, 4YL3, 5BQG, 5BQH, 5BQI, 5K0I, 5T36, 5T37, 5TL9, 6VL4, 8PYV
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01124	MAPEG	16 → 146	MAPEG family	Family

• Sequence:

  MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
  SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
  LRAPIRSVTYTLAQLPCASMALQILWEAARHL

• Sequence length: 152

Pathways

KEGG:

Arachidonic acid metabolism
Metabolic pathways

Reactome:

Synthesis of Prostaglandins (PG) and Thromboxanes (TX)

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANAL POLYP	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYDRONEPHROSIS	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 1 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	14520691, 18477251		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma Of Esophagus	Esophageal Cancer	BEFREE	19739114, 23439561		★☆☆☆☆ Found in Text Mining only
Adenoma of large intestine	Colorectal adenoma	BEFREE	11751489		★☆☆☆☆ Found in Text Mining only
Adenomatous Polyposis Coli	Multiple polyposis syndrome	BEFREE	19035518		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	18631945	Stimulate	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	19001348	Inhibit	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	19664621	Associate	★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	22537108		★☆☆☆☆ Found in Text Mining only
Aneurysm	Aneurysm	Pubtator	22588264	Associate	★☆☆☆☆ Found in Text Mining only
Anorexia	Anorexia	BEFREE	17878511, 27375005		★☆☆☆☆ Found in Text Mining only
Aortic Aneurysm	Aortic aneurysm	Pubtator	22588264	Associate	★☆☆☆☆ Found in Text Mining only
Aortic Aneurysm Abdominal	Aortic aneurysm	Pubtator	24133193, 24876670	Associate	★☆☆☆☆ Found in Text Mining only
Aortic Aneurysm, Abdominal	Aortic Aneurysm	BEFREE	22595380		★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	17878511		★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	BEFREE	11067848, 12835414, 15910650, 25314295, 28711625, 31229523		★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	Pubtator	15457451, 26225917, 32449517	Associate	★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	Pubtator	16255020	Stimulate	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	15188353, 16255020, 21298002, 21448233, 23488692, 33273889	Associate	★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	27611488		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Asthma	Asthma	GWASCAT_DG	27611488		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Asthma	Asthma	Pubtator	27611488	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Astrocytoma	Astrocytoma	BEFREE	16891468		★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	LHGDN	16891468		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	17878511		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	Pubtator	22588264	Associate	★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	29569150		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Barrett Esophagus	Barrett esophagus	BEFREE	18477251, 23439561, 31700071		★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	Pubtator	23439561	Associate	★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	Pubtator	31700071	Stimulate	★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar disorder	Pubtator	20038946	Stimulate	★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	16353170, 23624019, 28618256		★☆☆☆☆ Found in Text Mining only
Breast Diseases	Breast Diseases	BEFREE	16353170		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	18703630, 23913682	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	20635443	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	14520691, 15629771, 20034753		★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	20939114	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29610553, 31231223, 31285948, 31347609		★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	37108468, 40269781	Associate	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular disease	Pubtator	27159620	Associate	★☆☆☆☆ Found in Text Mining only
Carotid Artery Diseases	Carotid artery disease	LHGDN	16212965		★☆☆☆☆ Found in Text Mining only
Cerebral Aneurysm	Cerebral Aneurysm	BEFREE	21426319		★☆☆☆☆ Found in Text Mining only
Cerebrovascular accident	Stroke	BEFREE	16864802, 28478978		★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	BEFREE	21354147		★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	24839005	Associate	★☆☆☆☆ Found in Text Mining only
Chromosomal Instability	Chromosomal instability	Pubtator	25817443	Associate	★☆☆☆☆ Found in Text Mining only
Chronic kidney disease stage 5	Kidney Disease	BEFREE	26543101		★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	26543101		★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognitive disorder	BEFREE	29569150		★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	30619314		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	12818365, 26100239, 26352871, 26498686		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	12818365, 19035518, 19412621, 25817443		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	16495511, 20635443, 29237416	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	25817443, 26498686		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	25817443	Stimulate	★☆☆☆☆ Found in Text Mining only
Congenital contractural arachnodactyly	Congenital Contractural Arachnodactyly	BEFREE	23900502		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	15225371, 15910650, 18287210, 19428335, 22294637, 24886859, 28565823, 28694081, 29898737, 31666405		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	LHGDN	15868626		★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic retinopathy	Pubtator	37867507	Associate	★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	BEFREE	17295901, 23239446, 23252918, 31362919		★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	LHGDN	17295901		★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	Pubtator	23239446, 24035605	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	28458341, 31638830		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	20042640		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	20042640	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	20042640	Stimulate	★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty liver	Pubtator	37657050	Associate	★☆☆☆☆ Found in Text Mining only
Fatty Liver Disease	Fatty Liver	BEFREE	30382148		★☆☆☆☆ Found in Text Mining only
Gastritis	Gastritis	Pubtator	15531909	Associate	★☆☆☆☆ Found in Text Mining only
Gastrointestinal Diseases	Gastrointestinal disease	Pubtator	23778325	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	16891468, 31438982		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	27770821	Associate	★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	29273868		★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	21277871		★☆☆☆☆ Found in Text Mining only
Hirschsprung Disease	Hirschsprung Disease	BEFREE	30814036		★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	21385932	Associate	★☆☆☆☆ Found in Text Mining only
Hydronephrosis	Hydronephrosis	CTD_human_DG	22430074, 25015655		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypercholesterolemia	Hypercholesterolemia	BEFREE	29898737		★☆☆☆☆ Found in Text Mining only
Hyperplasia	Hyperplasia	Pubtator	22588264	Stimulate	★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	17641732, 29891646, 30992314, 31378107		★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	18050215, 20042640	Stimulate	★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	29569150, 31143112		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	LHGDN	14722058		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	14722058	Stimulate	★☆☆☆☆ Found in Text Mining only
Intestinal Obstruction	Intestinal Obstruction	BEFREE	29891860		★☆☆☆☆ Found in Text Mining only
Intracranial Aneurysm	Intracranial aneurysm	Pubtator	22588264	Associate	★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	19046748, 21816595, 28458341		★☆☆☆☆ Found in Text Mining only
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	BEFREE	30328712		★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney Disease	BEFREE	29104159		★☆☆☆☆ Found in Text Mining only
Kidney Failure Chronic	Kidney failure	Pubtator	34766335	Associate	★☆☆☆☆ Found in Text Mining only
Kidney Failure, Chronic	Kidney Failure	BEFREE	26543101		★☆☆☆☆ Found in Text Mining only
Leydig Cell Tumor	Leydig Cell Tumor	BEFREE	18619641		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	17696939, 21743491, 25108236		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	17696939		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	15471895		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	LHGDN	15870920, 16952028		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	17374734, 28662101, 31347609	Associate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	24839005	Stimulate	★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	18038187		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	16353170, 23624019, 28618256		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	31207300, 31231223, 31285948, 31347609		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	28419443		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	26113609, 27322147, 31715374		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	11751489, 16533161, 18477251, 20034753, 20497297, 21277871, 21907186, 23536473, 25108236, 26080408, 26511970, 27570080, 27688183, 27864144, 28419443, 28627961, 29129850, 29804818, 30537167, 30746063, 30827263, 30879343, 31231223, 31347609, 31562624		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	26100239, 26352871, 26498686		★☆☆☆☆ Found in Text Mining only
Marinesco-Sjogren syndrome	Marinesco-Sjogren Syndrome	BEFREE	25817443		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	26801201, 30538110		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	31819183	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	19995978, 29257087		★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	19046748, 30992314		★☆☆☆☆ Found in Text Mining only
Myositis	Myositis	Pubtator	18094001	Stimulate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12626523, 15471895, 15629771, 16952028, 18619641, 19035518, 20034753, 20043083, 20497297, 21277871, 21354147, 21743491, 22081067, 22815767, 23536473, 23624019, 25817443, 26080408, 26113609, 26498686, 27322147, 28096371, 28257996, 28419443, 29610553, 29804818, 30922080, 31285948		★☆☆☆☆ Found in Text Mining only
Nephrosclerosis	Nephrosclerosis	Pubtator	36690661	Associate	★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	26080408, 29804818, 31143112, 31562624		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	22537108		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	11555578, 16952028, 30922080, 31207300, 31285948		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	30349011		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	15225371, 18547825, 20109188, 23671648, 24886859, 25054223, 33273889	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	15457451	Stimulate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis Knee	Osteoarthritis	Pubtator	29898737, 30205824	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis, Knee	Knee osteoarthritis	BEFREE	30205824		★☆☆☆☆ Found in Text Mining only
Osteopenia	Osteopenia	BEFREE	30506812		★☆☆☆☆ Found in Text Mining only
Ovarian Failure, Premature	Ovarian Failure	BEFREE	28983734		★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	28419443		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	37108468	Associate	★☆☆☆☆ Found in Text Mining only
Papillary thyroid carcinoma	Papillary thyroid carcinoma	BEFREE	26511970		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	30423474		★☆☆☆☆ Found in Text Mining only
Patent ductus arteriosus	Patent ductus arteriosus	BEFREE	21372596		★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	BEFREE	21435451		★☆☆☆☆ Found in Text Mining only
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	30214544		★☆☆☆☆ Found in Text Mining only
Primary sclerosing cholangitis	Sclerosing Cholangitis	BEFREE	23900502		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	26113609, 27322147, 31715374		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	22799381, 34242345	Associate	★☆☆☆☆ Found in Text Mining only
Renal fibrosis	Renal fibrosis	BEFREE	27784694		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	12835414, 15910650, 18682561, 21448233, 28711625		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	LHGDN	14558087, 15188353, 17968936		★☆☆☆☆ Found in Text Mining only
Skin Neoplasms	Skin Neoplasms	BEFREE	28257996		★☆☆☆☆ Found in Text Mining only
Spondylitis Ankylosing	Ankylosing spondylitis	Pubtator	26225917	Stimulate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	LHGDN	14871981		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	22815767		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	20042640		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	20034753		★☆☆☆☆ Found in Text Mining only
Status Epilepticus	Status Epilepticus	BEFREE	31638830		★☆☆☆☆ Found in Text Mining only
Thymic Carcinoma	Thymic Carcinoma	BEFREE	16823844		★☆☆☆☆ Found in Text Mining only
Thyroid Cancer Papillary	Papillary thyroid cancer	Pubtator	26511970	Stimulate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	23913682	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	15629771	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Diseases	Uterine polyp	Pubtator	24035605	Associate	★☆☆☆☆ Found in Text Mining only
Varicose Veins	Varicose veins	Pubtator	24505358	Associate	★☆☆☆☆ Found in Text Mining only
Vascular System Injuries	Vascular system injury	Pubtator	22588264	Associate	★☆☆☆☆ Found in Text Mining only