TMEM59 (transmembrane protein 59)

Gene

• Entrez ID: 9528
• Gene name: Transmembrane protein 59
• Gene symbol: TMEM59
• Synonyms (NCBI Gene): C1orf8, DCF1, HSPC001, PRO195, UNQ169
• Chromosome: 1
• Chromosome location: 1p32.3
• Summary: This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs776119905	C>A,G,T	Risk-factor	Genic downstream transcript variant, 3 prime UTR variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005138	hsa-miR-30a-5p	pSILAC	18668040
MIRT005138	hsa-miR-30a-5p	Proteomics;Other	18668040
MIRT045645	hsa-miR-149-5p	CLASH	23622248
MIRT052744	hsa-miR-1260b	CLASH	23622248
MIRT663007	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT663006	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT663005	hsa-miR-940	HITS-CLIP	23824327
MIRT674702	hsa-miR-3929	HITS-CLIP	23824327
MIRT674701	hsa-miR-4419b	HITS-CLIP	23824327
MIRT674700	hsa-miR-4478	HITS-CLIP	23824327
MIRT663004	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT663003	hsa-miR-4257	HITS-CLIP	23824327
MIRT674699	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT674698	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT674697	hsa-miR-1827	HITS-CLIP	23824327
MIRT663002	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT663001	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT663000	hsa-miR-6134	HITS-CLIP	23824327
MIRT662999	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT613953	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT674696	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT674695	hsa-miR-665	HITS-CLIP	23824327
MIRT663007	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT663006	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT663005	hsa-miR-940	HITS-CLIP	23824327
MIRT663004	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT663003	hsa-miR-4257	HITS-CLIP	23824327
MIRT663002	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT663001	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT663000	hsa-miR-6134	HITS-CLIP	23824327
MIRT662999	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT662998	hsa-miR-490-3p	HITS-CLIP	23824327
MIRT662997	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT662996	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT662995	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT662994	hsa-miR-4459	HITS-CLIP	23824327
MIRT662993	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT662992	hsa-miR-544b	HITS-CLIP	23824327
MIRT662991	hsa-miR-7162-3p	HITS-CLIP	23824327
MIRT662990	hsa-miR-4299	HITS-CLIP	23824327
MIRT662989	hsa-miR-4786-5p	HITS-CLIP	23824327
MIRT662988	hsa-miR-5189-3p	HITS-CLIP	23824327
MIRT662987	hsa-miR-3926	HITS-CLIP	23824327
MIRT662986	hsa-miR-548s	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT637233	hsa-miR-6884-3p	HITS-CLIP	23824327
MIRT637232	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT637231	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT637230	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT637229	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT637228	hsa-miR-4319	HITS-CLIP	23824327
MIRT637227	hsa-miR-591	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT637226	hsa-miR-4281	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT637225	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT637224	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613958	hsa-miR-6761-5p	HITS-CLIP	23824327
MIRT613957	hsa-miR-93-3p	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613954	hsa-miR-4663	HITS-CLIP	23824327
MIRT613953	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT520579	hsa-miR-8077	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT520587	hsa-miR-4438	PAR-CLIP	23446348
MIRT520586	hsa-miR-3064-5p	PAR-CLIP	23446348
MIRT520585	hsa-miR-6504-5p	PAR-CLIP	23446348
MIRT520584	hsa-miR-6889-3p	PAR-CLIP	23446348
MIRT520583	hsa-miR-4252	PAR-CLIP	23446348
MIRT520582	hsa-miR-1254	PAR-CLIP	23446348
MIRT520581	hsa-miR-3116	PAR-CLIP	23446348
MIRT520580	hsa-miR-661	PAR-CLIP	23446348
MIRT520579	hsa-miR-8077	PAR-CLIP	23446348
MIRT520578	hsa-miR-1271-3p	PAR-CLIP	23446348
MIRT520577	hsa-miR-550a-3-5p	PAR-CLIP	23446348
MIRT520576	hsa-miR-550a-5p	PAR-CLIP	23446348
MIRT520575	hsa-miR-5095	PAR-CLIP	23446348
MIRT520574	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT520573	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT520572	hsa-miR-550b-2-5p	PAR-CLIP	23446348
MIRT439429	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT492061	hsa-miR-548m	PAR-CLIP	23592263
MIRT492059	hsa-miR-3974	PAR-CLIP	23592263
MIRT492060	hsa-miR-7852-3p	PAR-CLIP	23592263
MIRT492058	hsa-miR-584-3p	PAR-CLIP	23592263
MIRT492057	hsa-miR-3140-5p	PAR-CLIP	23592263
MIRT492056	hsa-miR-6073	PAR-CLIP	23592263
MIRT492055	hsa-miR-616-3p	PAR-CLIP	23592263
MIRT492054	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT492053	hsa-miR-1200	PAR-CLIP	23592263
MIRT439429	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT439429	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT663007	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT663006	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT663005	hsa-miR-940	HITS-CLIP	23824327
MIRT674702	hsa-miR-3929	HITS-CLIP	23824327
MIRT674701	hsa-miR-4419b	HITS-CLIP	23824327
MIRT674700	hsa-miR-4478	HITS-CLIP	23824327
MIRT663004	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT663003	hsa-miR-4257	HITS-CLIP	23824327
MIRT674699	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT674698	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT674697	hsa-miR-1827	HITS-CLIP	23824327
MIRT663002	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT663001	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT663000	hsa-miR-6134	HITS-CLIP	23824327
MIRT662999	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT613953	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT674696	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT674695	hsa-miR-665	HITS-CLIP	23824327
MIRT663007	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT663006	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT663005	hsa-miR-940	HITS-CLIP	23824327
MIRT663004	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT663003	hsa-miR-4257	HITS-CLIP	23824327
MIRT663002	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT663001	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT663000	hsa-miR-6134	HITS-CLIP	23824327
MIRT662999	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT662998	hsa-miR-490-3p	HITS-CLIP	23824327
MIRT662997	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT662996	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT662995	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT662994	hsa-miR-4459	HITS-CLIP	23824327
MIRT662993	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT662992	hsa-miR-544b	HITS-CLIP	23824327
MIRT662991	hsa-miR-7162-3p	HITS-CLIP	23824327
MIRT662990	hsa-miR-4299	HITS-CLIP	23824327
MIRT662989	hsa-miR-4786-5p	HITS-CLIP	23824327
MIRT662988	hsa-miR-5189-3p	HITS-CLIP	23824327
MIRT662987	hsa-miR-3926	HITS-CLIP	23824327
MIRT662986	hsa-miR-548s	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT637233	hsa-miR-6884-3p	HITS-CLIP	23824327
MIRT637232	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT637231	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT637230	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT637229	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT637228	hsa-miR-4319	HITS-CLIP	23824327
MIRT637227	hsa-miR-591	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT637226	hsa-miR-4281	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT637225	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT637224	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT613964	hsa-miR-224-3p	HITS-CLIP	23824327
MIRT613963	hsa-miR-522-3p	HITS-CLIP	23824327
MIRT613962	hsa-miR-383-5p	HITS-CLIP	23824327
MIRT613961	hsa-miR-8063	HITS-CLIP	23824327
MIRT613960	hsa-miR-4698	HITS-CLIP	23824327
MIRT613959	hsa-miR-4328	HITS-CLIP	23824327
MIRT613958	hsa-miR-6761-5p	HITS-CLIP	23824327
MIRT613957	hsa-miR-93-3p	HITS-CLIP	23824327
MIRT613956	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT613955	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT613954	hsa-miR-4663	HITS-CLIP	23824327
MIRT613953	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT520579	hsa-miR-8077	HITS-CLIP	23824327
MIRT613952	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613951	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613950	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613949	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT613948	hsa-miR-507	HITS-CLIP	23824327
MIRT613947	hsa-miR-557	HITS-CLIP	23824327
MIRT613946	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT520587	hsa-miR-4438	PAR-CLIP	23446348
MIRT520586	hsa-miR-3064-5p	PAR-CLIP	23446348
MIRT520585	hsa-miR-6504-5p	PAR-CLIP	23446348
MIRT520584	hsa-miR-6889-3p	PAR-CLIP	23446348
MIRT520583	hsa-miR-4252	PAR-CLIP	23446348
MIRT520582	hsa-miR-1254	PAR-CLIP	23446348
MIRT520581	hsa-miR-3116	PAR-CLIP	23446348
MIRT520580	hsa-miR-661	PAR-CLIP	23446348
MIRT520579	hsa-miR-8077	PAR-CLIP	23446348
MIRT520578	hsa-miR-1271-3p	PAR-CLIP	23446348
MIRT520577	hsa-miR-550a-3-5p	PAR-CLIP	23446348
MIRT520576	hsa-miR-550a-5p	PAR-CLIP	23446348
MIRT520575	hsa-miR-5095	PAR-CLIP	23446348
MIRT520574	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT520573	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT520572	hsa-miR-550b-2-5p	PAR-CLIP	23446348
MIRT439429	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT492061	hsa-miR-548m	PAR-CLIP	23592263
MIRT492059	hsa-miR-3974	PAR-CLIP	23592263
MIRT492060	hsa-miR-7852-3p	PAR-CLIP	23592263
MIRT492058	hsa-miR-584-3p	PAR-CLIP	23592263
MIRT492057	hsa-miR-3140-5p	PAR-CLIP	23592263
MIRT492056	hsa-miR-6073	PAR-CLIP	23592263
MIRT492055	hsa-miR-616-3p	PAR-CLIP	23592263
MIRT492054	hsa-miR-378a-5p	PAR-CLIP	23592263
MIRT492053	hsa-miR-1200	PAR-CLIP	23592263
MIRT1438208	hsa-miR-1245	CLIP-seq
MIRT1438209	hsa-miR-1253	CLIP-seq
MIRT1438210	hsa-miR-27a	CLIP-seq
MIRT1438211	hsa-miR-27b	CLIP-seq
MIRT1438212	hsa-miR-3689d	CLIP-seq
MIRT1438213	hsa-miR-383	CLIP-seq
MIRT1438214	hsa-miR-3908	CLIP-seq
MIRT1438215	hsa-miR-412	CLIP-seq
MIRT1438216	hsa-miR-4753-5p	CLIP-seq
MIRT1438217	hsa-miR-4772-5p	CLIP-seq
MIRT1438218	hsa-miR-513a-5p	CLIP-seq
MIRT1438219	hsa-miR-548p	CLIP-seq
MIRT1554973	hsa-miR-1207-5p	CLIP-seq
MIRT1438209	hsa-miR-1253	CLIP-seq
MIRT1554974	hsa-miR-144	CLIP-seq
MIRT1554975	hsa-miR-2681	CLIP-seq
MIRT1438212	hsa-miR-3689d	CLIP-seq
MIRT1438214	hsa-miR-3908	CLIP-seq
MIRT1554976	hsa-miR-4736	CLIP-seq
MIRT1554977	hsa-miR-4763-3p	CLIP-seq
MIRT1554974	hsa-miR-144	CLIP-seq
MIRT1554975	hsa-miR-2681	CLIP-seq
MIRT2131280	hsa-miR-3150b-3p	CLIP-seq
MIRT2131281	hsa-miR-4645-3p	CLIP-seq
MIRT2131282	hsa-miR-4689	CLIP-seq
MIRT2131283	hsa-miR-4760-5p	CLIP-seq
MIRT2131284	hsa-miR-4784	CLIP-seq
MIRT2131285	hsa-miR-590-3p	CLIP-seq
MIRT1554973	hsa-miR-1207-5p	CLIP-seq
MIRT1438208	hsa-miR-1245	CLIP-seq
MIRT1438209	hsa-miR-1253	CLIP-seq
MIRT1554974	hsa-miR-144	CLIP-seq
MIRT2352561	hsa-miR-2053	CLIP-seq
MIRT1554975	hsa-miR-2681	CLIP-seq
MIRT1438210	hsa-miR-27a	CLIP-seq
MIRT1438211	hsa-miR-27b	CLIP-seq
MIRT2352562	hsa-miR-298	CLIP-seq
MIRT2352563	hsa-miR-3074-5p	CLIP-seq
MIRT2352564	hsa-miR-33a	CLIP-seq
MIRT2352565	hsa-miR-33b	CLIP-seq
MIRT2352566	hsa-miR-3671	CLIP-seq
MIRT1438212	hsa-miR-3689d	CLIP-seq
MIRT2352567	hsa-miR-370	CLIP-seq
MIRT1438214	hsa-miR-3908	CLIP-seq
MIRT1438215	hsa-miR-412	CLIP-seq
MIRT2352568	hsa-miR-4265	CLIP-seq
MIRT2352569	hsa-miR-4296	CLIP-seq
MIRT2352570	hsa-miR-4322	CLIP-seq
MIRT2352571	hsa-miR-4324	CLIP-seq
MIRT2352572	hsa-miR-4417	CLIP-seq
MIRT2352573	hsa-miR-4468	CLIP-seq
MIRT2352574	hsa-miR-4640-5p	CLIP-seq
MIRT2131281	hsa-miR-4645-3p	CLIP-seq
MIRT2352575	hsa-miR-4726-5p	CLIP-seq
MIRT1554976	hsa-miR-4736	CLIP-seq
MIRT1554977	hsa-miR-4763-3p	CLIP-seq
MIRT2352576	hsa-miR-513a-3p	CLIP-seq
MIRT1438218	hsa-miR-513a-5p	CLIP-seq
MIRT2352577	hsa-miR-607	CLIP-seq
MIRT1554973	hsa-miR-1207-5p	CLIP-seq
MIRT1438209	hsa-miR-1253	CLIP-seq
MIRT1554974	hsa-miR-144	CLIP-seq
MIRT2352561	hsa-miR-2053	CLIP-seq
MIRT1554975	hsa-miR-2681	CLIP-seq
MIRT2441380	hsa-miR-3129-3p	CLIP-seq
MIRT1438212	hsa-miR-3689d	CLIP-seq
MIRT2131281	hsa-miR-4645-3p	CLIP-seq
MIRT1554976	hsa-miR-4736	CLIP-seq
MIRT1554977	hsa-miR-4763-3p	CLIP-seq
MIRT2352561	hsa-miR-2053	CLIP-seq
MIRT2441380	hsa-miR-3129-3p	CLIP-seq
MIRT2646313	hsa-miR-103b	CLIP-seq
MIRT1554973	hsa-miR-1207-5p	CLIP-seq
MIRT1438209	hsa-miR-1253	CLIP-seq
MIRT1554974	hsa-miR-144	CLIP-seq
MIRT1554975	hsa-miR-2681	CLIP-seq
MIRT2646314	hsa-miR-3148	CLIP-seq
MIRT2131280	hsa-miR-3150b-3p	CLIP-seq
MIRT2646315	hsa-miR-330-3p	CLIP-seq
MIRT2646316	hsa-miR-3613-3p	CLIP-seq
MIRT1438212	hsa-miR-3689d	CLIP-seq
MIRT2646317	hsa-miR-369-3p	CLIP-seq
MIRT2646318	hsa-miR-374c	CLIP-seq
MIRT1438213	hsa-miR-383	CLIP-seq
MIRT1438214	hsa-miR-3908	CLIP-seq
MIRT2131281	hsa-miR-4645-3p	CLIP-seq
MIRT2646319	hsa-miR-4666-3p	CLIP-seq
MIRT2646320	hsa-miR-4668-5p	CLIP-seq
MIRT2131282	hsa-miR-4689	CLIP-seq
MIRT2646321	hsa-miR-4733-5p	CLIP-seq
MIRT1554976	hsa-miR-4736	CLIP-seq
MIRT2131283	hsa-miR-4760-5p	CLIP-seq
MIRT1554977	hsa-miR-4763-3p	CLIP-seq
MIRT1438217	hsa-miR-4772-5p	CLIP-seq
MIRT2131284	hsa-miR-4784	CLIP-seq
MIRT1438219	hsa-miR-548p	CLIP-seq
MIRT2646322	hsa-miR-548v	CLIP-seq
MIRT2646323	hsa-miR-576-3p	CLIP-seq
MIRT2131285	hsa-miR-590-3p	CLIP-seq
MIRT2646324	hsa-miR-655	CLIP-seq
MIRT2646313	hsa-miR-103b	CLIP-seq
MIRT1554973	hsa-miR-1207-5p	CLIP-seq
MIRT1438209	hsa-miR-1253	CLIP-seq
MIRT2693560	hsa-miR-1283	CLIP-seq
MIRT2693561	hsa-miR-142-5p	CLIP-seq
MIRT1554974	hsa-miR-144	CLIP-seq
MIRT1554975	hsa-miR-2681	CLIP-seq
MIRT1438210	hsa-miR-27a	CLIP-seq
MIRT1438211	hsa-miR-27b	CLIP-seq
MIRT2646314	hsa-miR-3148	CLIP-seq
MIRT2131280	hsa-miR-3150b-3p	CLIP-seq
MIRT2646315	hsa-miR-330-3p	CLIP-seq
MIRT2646316	hsa-miR-3613-3p	CLIP-seq
MIRT1438212	hsa-miR-3689d	CLIP-seq
MIRT2646317	hsa-miR-369-3p	CLIP-seq
MIRT2646318	hsa-miR-374c	CLIP-seq
MIRT1438213	hsa-miR-383	CLIP-seq
MIRT1438214	hsa-miR-3908	CLIP-seq
MIRT1438215	hsa-miR-412	CLIP-seq
MIRT2131281	hsa-miR-4645-3p	CLIP-seq
MIRT2646319	hsa-miR-4666-3p	CLIP-seq
MIRT2646320	hsa-miR-4668-5p	CLIP-seq
MIRT2131282	hsa-miR-4689	CLIP-seq
MIRT2646321	hsa-miR-4733-5p	CLIP-seq
MIRT1554976	hsa-miR-4736	CLIP-seq
MIRT2131283	hsa-miR-4760-5p	CLIP-seq
MIRT1554977	hsa-miR-4763-3p	CLIP-seq
MIRT1438217	hsa-miR-4772-5p	CLIP-seq
MIRT2131284	hsa-miR-4784	CLIP-seq
MIRT2693562	hsa-miR-4796-5p	CLIP-seq
MIRT1438218	hsa-miR-513a-5p	CLIP-seq
MIRT1438219	hsa-miR-548p	CLIP-seq
MIRT2646322	hsa-miR-548v	CLIP-seq
MIRT2693563	hsa-miR-561	CLIP-seq
MIRT2646323	hsa-miR-576-3p	CLIP-seq
MIRT2131285	hsa-miR-590-3p	CLIP-seq
MIRT2646324	hsa-miR-655	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000137	Component	Golgi cis cisterna	IDA	20427278
GO:0000138	Component	Golgi trans cisterna	IDA	20427278
GO:0000139	Component	Golgi membrane	IEA
GO:0004175	Function	Endopeptidase activity	IEA
GO:0005515	Function	Protein binding	IPI	23376921
GO:0005764	Component	Lysosome	IBA
GO:0005764	Component	Lysosome	IDA	23376921
GO:0005764	Component	Lysosome	IEA
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005768	Component	Endosome	IEA
GO:0005770	Component	Late endosome	IBA
GO:0005770	Component	Late endosome	IDA	23376921
GO:0005794	Component	Golgi apparatus	IEA
GO:0005797	Component	Golgi medial cisterna	IDA	20427278
GO:0005886	Component	Plasma membrane	IEA
GO:0006486	Process	Protein glycosylation	IDA	20427278
GO:0006914	Process	Autophagy	IEA
GO:0010508	Process	Positive regulation of autophagy	IBA
GO:0010508	Process	Positive regulation of autophagy	IMP	23376921
GO:0016020	Component	Membrane	IEA
GO:0031902	Component	Late endosome membrane	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1903077	Process	Negative regulation of protein localization to plasma membrane	IDA	20427278

Other IDs

• MIM: 617084
• HGNC: 1239
• e!Ensembl: ENSG00000116209

Protein

• UniProt ID: Q9BXS4
• Protein name: Transmembrane protein 59 (Liver membrane-bound protein)
• Protein function: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting L
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12280	BSMAP	72 → 256	Brain specific membrane anchored protein	Family

• Sequence:

  MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHT
  YPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQ
  LPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIF
  QSKPEIQYAPHLEQEPTNLRESSLSKMSYLQMRNSQAHRNFLEDGESDGFLRCLSLNSGW
  ILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGDLEFMNEQKLNRYPASSLVVVR
  SKTEDHEEAGPLPTKVNLAHSEI

• Sequence length: 323

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ESTROGEN RESISTANCE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Estrogen resistance syndrome	risk factor	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	22451312	Associate	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease, Late Onset	Alzheimer disease	BEFREE	22451312		★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety Disorder	BEFREE	31531752		★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	31531752		★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	17543375	Associate	★☆☆☆☆ Found in Text Mining only
Central Nervous System Diseases	Central nervous system disease	Pubtator	34799992	Associate	★☆☆☆☆ Found in Text Mining only
ESTROGEN RESISTANCE	Estrogen Resistance	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Glioblastoma	Glioblastoma	BEFREE	30001801		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	34799992	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	30001801		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	24424470, 30104955		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	34799992	Associate	★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	32664164	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	24424470		★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	34799992	Associate	★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	30365123		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	29649746		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	25663231	Associate	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	29649746		★☆☆☆☆ Found in Text Mining only
Ventricular Remodeling	Ventricular remodeling	Pubtator	32664164	Associate	★☆☆☆☆ Found in Text Mining only