Gene Gene information from NCBI Gene database.
Entrez ID 9522
Gene name Secretory carrier membrane protein 1
Gene symbol SCAMP1
Synonyms (NCBI Gene)
SCAMPSCAMP37
Chromosome 5
Chromosome location 5q14.1
Summary This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct gene
miRNA miRNA information provided by mirtarbase database.
871
miRTarBase ID miRNA Experiments Reference
MIRT001504 hsa-miR-155-5p pSILAC 18668040
MIRT018181 hsa-miR-335-5p Microarray 18185580
MIRT001504 hsa-miR-155-5p Proteomics;Other 18668040
MIRT032318 hsa-let-7b-5p Proteomics 18668040
MIRT036427 hsa-miR-1226-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 15840657, 25416956, 28514442, 32296183, 32814053, 33961781, 35156780, 36012204
GO:0005768 Component Endosome IEA
GO:0005794 Component Golgi apparatus IEA
GO:0005802 Component Trans-Golgi network IDA 15840657
GO:0005886 Component Plasma membrane TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606911 10563 ENSG00000085365
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O15126
Protein name Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1)
Protein function Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04144 SCAMP 117 292 SCAMP family Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed, with highest expression in brain.
Sequence
MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGGVKMPNVPNTQ
PAIMKPTEEHPAYTQIAKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNW
PPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSAR
AVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFH
NWGNCGWISSLTGLNQNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTT
GASFEKAQ
QEFATGVMSNKTVQTAAANAASTAASSAAQNAFKGNQI
Sequence length 338
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
BIPOLAR DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCOLIOSIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Carcinoma Breast Carcinoma BEFREE 29497041
★☆☆☆☆
Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma Renal Carcinoma BEFREE 31550675
★☆☆☆☆
Found in Text Mining only
Gallbladder Carcinoma Gallbladder cancer BEFREE 23653380
★☆☆☆☆
Found in Text Mining only
Gastritis Gastritis Pubtator 37249580 Associate
★☆☆☆☆
Found in Text Mining only
Immune thrombocytopenic purpura Immune Thrombocytopenic Purpura BEFREE 27781392
★☆☆☆☆
Found in Text Mining only
Lymphatic Metastasis Lymphatic metastasis Pubtator 23653380 Stimulate
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer BEFREE 29497041
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of gallbladder Gallbladder cancer BEFREE 23653380
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of pancreas Pancreatic cancer BEFREE 23653380
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 18191186
★☆☆☆☆
Found in Text Mining only