Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	9399
Gene name	Stomatin like 1
Gene symbol	STOML1
Synonyms (NCBI Gene)	SLP-1STORPhUNC-24
Chromosome	15
Chromosome location	15q24.1

137

Show/Hide all (137)

miRTarBase ID	miRNA	Experiments	Reference
MIRT669823	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669822	hsa-miR-764	HITS-CLIP	23824327
MIRT669821	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT669820	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT669819	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT669818	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT669817	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT669816	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT669815	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT669814	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT669813	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT669811	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669812	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT669810	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669809	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669808	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT669807	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669806	hsa-miR-640	HITS-CLIP	23824327
MIRT669805	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT669804	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641874	hsa-miR-8485	HITS-CLIP	23824327
MIRT641873	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT641872	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641870	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT641869	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT641868	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT641867	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT641866	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT641865	hsa-miR-4469	HITS-CLIP	23824327
MIRT641864	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT641863	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT641862	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT641861	hsa-miR-6837-3p	HITS-CLIP	23824327
MIRT641860	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT641859	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT641858	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT514497	hsa-miR-5692a	PAR-CLIP	23446348
MIRT514495	hsa-miR-6858-3p	PAR-CLIP	23446348
MIRT514494	hsa-miR-3197	PAR-CLIP	23446348
MIRT514493	hsa-miR-3194-5p	PAR-CLIP	23446348
MIRT514492	hsa-miR-877-5p	PAR-CLIP	23446348
MIRT514491	hsa-miR-6866-5p	PAR-CLIP	23446348
MIRT669823	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669822	hsa-miR-764	HITS-CLIP	23824327
MIRT669821	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT669820	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT669819	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT669818	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT669817	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT669816	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT669815	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT669814	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT669813	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT669811	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669812	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT669810	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669809	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669808	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT669807	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669806	hsa-miR-640	HITS-CLIP	23824327
MIRT669805	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT669804	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641874	hsa-miR-8485	HITS-CLIP	23824327
MIRT641873	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT641872	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641870	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT641869	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT641868	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT641867	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT641866	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT641865	hsa-miR-4469	HITS-CLIP	23824327
MIRT641864	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT641863	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT641862	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT641861	hsa-miR-6837-3p	HITS-CLIP	23824327
MIRT641860	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT641859	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT641858	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT514497	hsa-miR-5692a	PAR-CLIP	23446348
MIRT514495	hsa-miR-6858-3p	PAR-CLIP	23446348
MIRT514494	hsa-miR-3197	PAR-CLIP	23446348
MIRT514493	hsa-miR-3194-5p	PAR-CLIP	23446348
MIRT514492	hsa-miR-877-5p	PAR-CLIP	23446348
MIRT514491	hsa-miR-6866-5p	PAR-CLIP	23446348
MIRT1399003	hsa-miR-1258	CLIP-seq
MIRT1399004	hsa-miR-1296	CLIP-seq
MIRT1399005	hsa-miR-2909	CLIP-seq
MIRT1399006	hsa-miR-4512	CLIP-seq
MIRT2119621	hsa-miR-2355-5p	CLIP-seq
MIRT2119622	hsa-miR-2861	CLIP-seq
MIRT2119623	hsa-miR-3652	CLIP-seq
MIRT2119624	hsa-miR-4430	CLIP-seq
MIRT2119625	hsa-miR-4487	CLIP-seq
MIRT2119626	hsa-miR-4505	CLIP-seq
MIRT2119627	hsa-miR-4661-3p	CLIP-seq
MIRT2119628	hsa-miR-4726-3p	CLIP-seq
MIRT2119629	hsa-miR-647	CLIP-seq
MIRT2341763	hsa-miR-1183	CLIP-seq
MIRT2341764	hsa-miR-1291	CLIP-seq
MIRT2341765	hsa-miR-198	CLIP-seq
MIRT2341766	hsa-miR-214	CLIP-seq
MIRT2341767	hsa-miR-3173-5p	CLIP-seq
MIRT2341768	hsa-miR-3619-5p	CLIP-seq
MIRT2341769	hsa-miR-3667-3p	CLIP-seq
MIRT2341770	hsa-miR-3919	CLIP-seq
MIRT2341771	hsa-miR-3925-5p	CLIP-seq
MIRT2341772	hsa-miR-4268	CLIP-seq
MIRT2341773	hsa-miR-4448	CLIP-seq
MIRT2341774	hsa-miR-520a-5p	CLIP-seq
MIRT2341775	hsa-miR-525-5p	CLIP-seq
MIRT2341776	hsa-miR-589	CLIP-seq
MIRT2341777	hsa-miR-761	CLIP-seq
MIRT2635678	hsa-miR-1207-3p	CLIP-seq
MIRT2635679	hsa-miR-1228	CLIP-seq
MIRT2635680	hsa-miR-1285	CLIP-seq
MIRT2635681	hsa-miR-1973	CLIP-seq
MIRT2341765	hsa-miR-198	CLIP-seq
MIRT2635682	hsa-miR-3144-5p	CLIP-seq
MIRT2635683	hsa-miR-3187-5p	CLIP-seq
MIRT2635684	hsa-miR-3191	CLIP-seq
MIRT2341770	hsa-miR-3919	CLIP-seq
MIRT2341771	hsa-miR-3925-5p	CLIP-seq
MIRT2635685	hsa-miR-4267	CLIP-seq
MIRT2635686	hsa-miR-4312	CLIP-seq
MIRT2635687	hsa-miR-4652-5p	CLIP-seq
MIRT2635688	hsa-miR-4667-5p	CLIP-seq
MIRT2635689	hsa-miR-4700-5p	CLIP-seq
MIRT2635690	hsa-miR-4731-5p	CLIP-seq
MIRT2635691	hsa-miR-512-5p	CLIP-seq
MIRT2341774	hsa-miR-520a-5p	CLIP-seq
MIRT2341775	hsa-miR-525-5p	CLIP-seq
MIRT2341776	hsa-miR-589	CLIP-seq
MIRT2635692	hsa-miR-612	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19696025, 23082202
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0006869	Process	Lipid transport	IEA
GO:0008200	Function	Ion channel inhibitor activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031902	Component	Late endosome membrane	IEA
GO:0045121	Component	Membrane raft	IEA

MIM	HGNC	e!Ensembl
608326	14560	ENSG00000067221

Q9UBI4

Protein name

Stomatin-like protein 1 (SLP-1) (EPB72-like protein 1) (Protein unc-24 homolog) (Stomatin-related protein) (STORP)

Protein function

May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of A

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01145	Band_7	80 → 228	SPFH domain / Band 7 family	Family
PF02036	SCP2	291 → 395	SCP-2 sterol transfer family	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed at low levels. Expression is highest in brain. {ECO:0000269|PubMed:10997330, ECO:0000269|PubMed:9931417}.

Sequence

MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLIS
FLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLR
TRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLK
RPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQ
QLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQP
FLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLR
ALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK

Sequence length

398

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CORONARY ARTERY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SAPHO SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (9)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Autistic Disorder	Autism	Pubtator	11121177	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	30950057		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bulbo-Spinal Atrophy, X-Linked	Bulbospinal Atrophy, X-Linked	BEFREE	27179633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	19034969	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	GWASCAT_DG	29212778		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant neoplasm of breast	Breast Cancer	BEFREE	30950057		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mucocutaneous Lymph Node Syndrome	Kawasaki disease	BEFREE	27179633		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12051873		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	24007313	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

STOML1 (stomatin like 1)