Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	93349
Gene name	SP140 nuclear body protein like
Gene symbol	SP140L
Synonyms (NCBI Gene)	-
Chromosome	2
Chromosome location	2q37.1

200

Show/Hide all (200)

miRTarBase ID	miRNA	Experiments	Reference
MIRT643827	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT643826	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT643825	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT643824	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT643823	hsa-miR-3189-3p	HITS-CLIP	23824327
MIRT643822	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT643821	hsa-miR-711	HITS-CLIP	23824327
MIRT643820	hsa-miR-3649	HITS-CLIP	23824327
MIRT643819	hsa-miR-585-5p	HITS-CLIP	23824327
MIRT643818	hsa-miR-4684-5p	HITS-CLIP	23824327
MIRT643817	hsa-miR-1302	HITS-CLIP	23824327
MIRT643816	hsa-miR-4298	HITS-CLIP	23824327
MIRT643815	hsa-miR-3122	HITS-CLIP	23824327
MIRT643814	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT643818	hsa-miR-4684-5p	PAR-CLIP	27292025
MIRT643818	hsa-miR-4684-5p	PAR-CLIP	27292025
MIRT643827	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT643826	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT643825	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT643824	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT643823	hsa-miR-3189-3p	HITS-CLIP	23824327
MIRT643822	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT643821	hsa-miR-711	HITS-CLIP	23824327
MIRT643820	hsa-miR-3649	HITS-CLIP	23824327
MIRT643819	hsa-miR-585-5p	HITS-CLIP	23824327
MIRT643818	hsa-miR-4684-5p	HITS-CLIP	23824327
MIRT643817	hsa-miR-1302	HITS-CLIP	23824327
MIRT643816	hsa-miR-4298	HITS-CLIP	23824327
MIRT643815	hsa-miR-3122	HITS-CLIP	23824327
MIRT643814	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT1381183	hsa-miR-1184	CLIP-seq
MIRT1381184	hsa-miR-1185	CLIP-seq
MIRT1381185	hsa-miR-1205	CLIP-seq
MIRT1381186	hsa-miR-1224-5p	CLIP-seq
MIRT1381187	hsa-miR-1272	CLIP-seq
MIRT1381188	hsa-miR-1304	CLIP-seq
MIRT1381189	hsa-miR-140-3p	CLIP-seq
MIRT1381190	hsa-miR-1909	CLIP-seq
MIRT1381191	hsa-miR-219-1-3p	CLIP-seq
MIRT1381192	hsa-miR-3158-5p	CLIP-seq
MIRT1381193	hsa-miR-3160-3p	CLIP-seq
MIRT1381194	hsa-miR-3605-5p	CLIP-seq
MIRT1381195	hsa-miR-3606	CLIP-seq
MIRT1381196	hsa-miR-3679-5p	CLIP-seq
MIRT1381197	hsa-miR-3682-3p	CLIP-seq
MIRT1381198	hsa-miR-3915	CLIP-seq
MIRT1381199	hsa-miR-4257	CLIP-seq
MIRT1381200	hsa-miR-4270	CLIP-seq
MIRT1381201	hsa-miR-4307	CLIP-seq
MIRT1381202	hsa-miR-433	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT1381204	hsa-miR-4441	CLIP-seq
MIRT1381205	hsa-miR-4459	CLIP-seq
MIRT1381206	hsa-miR-4487	CLIP-seq
MIRT1381207	hsa-miR-4689	CLIP-seq
MIRT1381208	hsa-miR-4767	CLIP-seq
MIRT1381209	hsa-miR-507	CLIP-seq
MIRT1381210	hsa-miR-513a-3p	CLIP-seq
MIRT1381211	hsa-miR-544	CLIP-seq
MIRT1381212	hsa-miR-557	CLIP-seq
MIRT1381213	hsa-miR-558	CLIP-seq
MIRT1381214	hsa-miR-890	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT1381205	hsa-miR-4459	CLIP-seq
MIRT2114081	hsa-miR-1245b-3p	CLIP-seq
MIRT2114082	hsa-miR-302a	CLIP-seq
MIRT2114083	hsa-miR-302b	CLIP-seq
MIRT2114084	hsa-miR-302c	CLIP-seq
MIRT2114085	hsa-miR-302d	CLIP-seq
MIRT2114086	hsa-miR-302e	CLIP-seq
MIRT2114087	hsa-miR-3117-5p	CLIP-seq
MIRT2114088	hsa-miR-3154	CLIP-seq
MIRT2114089	hsa-miR-34b	CLIP-seq
MIRT1381195	hsa-miR-3606	CLIP-seq
MIRT2114090	hsa-miR-372	CLIP-seq
MIRT2114091	hsa-miR-373	CLIP-seq
MIRT1381199	hsa-miR-4257	CLIP-seq
MIRT2114092	hsa-miR-4264	CLIP-seq
MIRT2114093	hsa-miR-4328	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT2114094	hsa-miR-4797-3p	CLIP-seq
MIRT1381209	hsa-miR-507	CLIP-seq
MIRT2114095	hsa-miR-514	CLIP-seq
MIRT2114096	hsa-miR-514b-3p	CLIP-seq
MIRT2114097	hsa-miR-520a-3p	CLIP-seq
MIRT2114098	hsa-miR-520b	CLIP-seq
MIRT2114099	hsa-miR-520c-3p	CLIP-seq
MIRT2114100	hsa-miR-520d-3p	CLIP-seq
MIRT2114101	hsa-miR-520e	CLIP-seq
MIRT1381212	hsa-miR-557	CLIP-seq
MIRT1381193	hsa-miR-3160-3p	CLIP-seq
MIRT2114089	hsa-miR-34b	CLIP-seq
MIRT1381199	hsa-miR-4257	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT1381205	hsa-miR-4459	CLIP-seq
MIRT1381206	hsa-miR-4487	CLIP-seq
MIRT1381213	hsa-miR-558	CLIP-seq
MIRT1381214	hsa-miR-890	CLIP-seq
MIRT1381195	hsa-miR-3606	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT1381205	hsa-miR-4459	CLIP-seq
MIRT2460325	hsa-miR-1285	CLIP-seq
MIRT2460326	hsa-miR-3187-5p	CLIP-seq
MIRT2114089	hsa-miR-34b	CLIP-seq
MIRT2460327	hsa-miR-3613-3p	CLIP-seq
MIRT2460328	hsa-miR-3622b-5p	CLIP-seq
MIRT2460329	hsa-miR-3945	CLIP-seq
MIRT2460330	hsa-miR-4253	CLIP-seq
MIRT2460331	hsa-miR-612	CLIP-seq
MIRT2460327	hsa-miR-3613-3p	CLIP-seq
MIRT1381183	hsa-miR-1184	CLIP-seq
MIRT1381185	hsa-miR-1205	CLIP-seq
MIRT2460325	hsa-miR-1285	CLIP-seq
MIRT2630522	hsa-miR-134	CLIP-seq
MIRT1381189	hsa-miR-140-3p	CLIP-seq
MIRT1381190	hsa-miR-1909	CLIP-seq
MIRT1381191	hsa-miR-219-1-3p	CLIP-seq
MIRT2114087	hsa-miR-3117-5p	CLIP-seq
MIRT2630523	hsa-miR-3118	CLIP-seq
MIRT2630524	hsa-miR-3133	CLIP-seq
MIRT1381192	hsa-miR-3158-5p	CLIP-seq
MIRT1381193	hsa-miR-3160-3p	CLIP-seq
MIRT2630525	hsa-miR-3179	CLIP-seq
MIRT2630526	hsa-miR-3185	CLIP-seq
MIRT2460326	hsa-miR-3187-5p	CLIP-seq
MIRT2630527	hsa-miR-320a	CLIP-seq
MIRT2630528	hsa-miR-320b	CLIP-seq
MIRT2630529	hsa-miR-320c	CLIP-seq
MIRT2630530	hsa-miR-320d	CLIP-seq
MIRT2630531	hsa-miR-33a	CLIP-seq
MIRT2630532	hsa-miR-33b	CLIP-seq
MIRT2114089	hsa-miR-34b	CLIP-seq
MIRT1381195	hsa-miR-3606	CLIP-seq
MIRT2460327	hsa-miR-3613-3p	CLIP-seq
MIRT2460328	hsa-miR-3622b-5p	CLIP-seq
MIRT2630533	hsa-miR-3652	CLIP-seq
MIRT2630534	hsa-miR-3672	CLIP-seq
MIRT2630535	hsa-miR-371-5p	CLIP-seq
MIRT2630536	hsa-miR-371b-5p	CLIP-seq
MIRT2460329	hsa-miR-3945	CLIP-seq
MIRT2460330	hsa-miR-4253	CLIP-seq
MIRT1381199	hsa-miR-4257	CLIP-seq
MIRT1381200	hsa-miR-4270	CLIP-seq
MIRT2630537	hsa-miR-4429	CLIP-seq
MIRT2630538	hsa-miR-4430	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT2630539	hsa-miR-4440	CLIP-seq
MIRT1381204	hsa-miR-4441	CLIP-seq
MIRT2630540	hsa-miR-4453	CLIP-seq
MIRT1381205	hsa-miR-4459	CLIP-seq
MIRT1381206	hsa-miR-4487	CLIP-seq
MIRT2630541	hsa-miR-4505	CLIP-seq
MIRT2630542	hsa-miR-4532	CLIP-seq
MIRT2630543	hsa-miR-4538	CLIP-seq
MIRT2630544	hsa-miR-4693-3p	CLIP-seq
MIRT1381208	hsa-miR-4767	CLIP-seq
MIRT2630545	hsa-miR-4795-5p	CLIP-seq
MIRT2630546	hsa-miR-485-3p	CLIP-seq
MIRT1381211	hsa-miR-544	CLIP-seq
MIRT1381213	hsa-miR-558	CLIP-seq
MIRT2630547	hsa-miR-595	CLIP-seq
MIRT2630548	hsa-miR-610	CLIP-seq
MIRT2460331	hsa-miR-612	CLIP-seq
MIRT2630549	hsa-miR-647	CLIP-seq
MIRT2630550	hsa-miR-892a	CLIP-seq
MIRT2630551	hsa-miR-943	CLIP-seq
MIRT1381183	hsa-miR-1184	CLIP-seq
MIRT1381185	hsa-miR-1205	CLIP-seq
MIRT2460325	hsa-miR-1285	CLIP-seq
MIRT1381189	hsa-miR-140-3p	CLIP-seq
MIRT1381190	hsa-miR-1909	CLIP-seq
MIRT1381191	hsa-miR-219-1-3p	CLIP-seq
MIRT2114087	hsa-miR-3117-5p	CLIP-seq
MIRT2630524	hsa-miR-3133	CLIP-seq
MIRT1381192	hsa-miR-3158-5p	CLIP-seq
MIRT1381193	hsa-miR-3160-3p	CLIP-seq
MIRT2630525	hsa-miR-3179	CLIP-seq
MIRT2630526	hsa-miR-3185	CLIP-seq
MIRT2460326	hsa-miR-3187-5p	CLIP-seq
MIRT2114089	hsa-miR-34b	CLIP-seq
MIRT1381195	hsa-miR-3606	CLIP-seq
MIRT2460327	hsa-miR-3613-3p	CLIP-seq
MIRT2460329	hsa-miR-3945	CLIP-seq
MIRT2460330	hsa-miR-4253	CLIP-seq
MIRT1381199	hsa-miR-4257	CLIP-seq
MIRT1381200	hsa-miR-4270	CLIP-seq
MIRT1381203	hsa-miR-4433	CLIP-seq
MIRT2630539	hsa-miR-4440	CLIP-seq
MIRT1381204	hsa-miR-4441	CLIP-seq
MIRT1381205	hsa-miR-4459	CLIP-seq
MIRT1381206	hsa-miR-4487	CLIP-seq
MIRT2630544	hsa-miR-4693-3p	CLIP-seq
MIRT1381208	hsa-miR-4767	CLIP-seq
MIRT2630545	hsa-miR-4795-5p	CLIP-seq
MIRT2630546	hsa-miR-485-3p	CLIP-seq
MIRT1381211	hsa-miR-544	CLIP-seq
MIRT1381213	hsa-miR-558	CLIP-seq
MIRT2630547	hsa-miR-595	CLIP-seq
MIRT2630548	hsa-miR-610	CLIP-seq
MIRT2460331	hsa-miR-612	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006952	Process	Defense response	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
617747	25105	ENSG00000185404

Q9H930

Protein name

Nuclear body protein SP140-like protein

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03172	HSR	49 → 147	HSR domain	Domain
PF01342	SAND	297 → 373	SAND domain	Family
PF00628	PHD	405 → 449	PHD-finger	Domain
PF00439	Bromodomain	477 → 555	Bromodomain	Domain

Sequence

MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH
KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS
VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQGEVPES
PEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDNSKAD
GQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETVDFQA
PLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCG
GWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDT
CSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLL
LKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIF
QNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS

Sequence length

580

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
LYMPHOID LEUKEMIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE MYELOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SARCOIDOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Primary biliary cirrhosis	Biliary Cirrhosis	BEFREE	26347895		★★★★★ ★☆☆☆☆ Found in Text Mining only

SP140L (SP140 nuclear body protein like)