GTF3C4 (general transcription factor IIIC subunit 4)

Gene

• Entrez ID: 9329
• Gene name: General transcription factor IIIC subunit 4
• Gene symbol: GTF3C4
• Synonyms (NCBI Gene): KAT12, TF3C-delta, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA
• Chromosome: 9
• Chromosome location: 9q34.13

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028677	hsa-miR-30a-5p	Proteomics	18668040
MIRT031966	hsa-miR-16-5p	Proteomics	18668040
MIRT032467	hsa-let-7b-5p	Proteomics	18668040
MIRT044408	hsa-miR-320a	CLASH	23622248
MIRT044408	hsa-miR-320a	CLASH	23622248
MIRT043336	hsa-miR-331-3p	CLASH	23622248
MIRT039620	hsa-miR-615-3p	CLASH	23622248
MIRT684335	hsa-miR-3646	HITS-CLIP	23313552
MIRT684334	hsa-miR-3184-3p	HITS-CLIP	23313552
MIRT684333	hsa-miR-1182	HITS-CLIP	23313552
MIRT684332	hsa-miR-1324	HITS-CLIP	23313552
MIRT043336	hsa-miR-331-3p	HITS-CLIP	23313552
MIRT684331	hsa-miR-6892-3p	HITS-CLIP	23313552
MIRT684330	hsa-miR-2276-5p	HITS-CLIP	23313552
MIRT684329	hsa-miR-4308	HITS-CLIP	23313552
MIRT684328	hsa-miR-3183	HITS-CLIP	23313552
MIRT684327	hsa-miR-4723-3p	HITS-CLIP	23313552
MIRT684326	hsa-miR-6769b-3p	HITS-CLIP	23313552
MIRT684325	hsa-miR-1304-3p	HITS-CLIP	23313552
MIRT684324	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT684323	hsa-miR-3925-3p	HITS-CLIP	23313552
MIRT684322	hsa-miR-1251-5p	HITS-CLIP	23313552
MIRT684321	hsa-miR-1199-5p	HITS-CLIP	23313552
MIRT684320	hsa-miR-6751-3p	HITS-CLIP	23313552
MIRT240700	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT684319	hsa-miR-6128	HITS-CLIP	23313552
MIRT684318	hsa-miR-494-3p	HITS-CLIP	23313552
MIRT684317	hsa-miR-6846-3p	HITS-CLIP	23313552
MIRT684316	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT684315	hsa-miR-558	HITS-CLIP	23313552
MIRT684314	hsa-miR-4487	HITS-CLIP	23313552
MIRT684313	hsa-miR-642a-5p	HITS-CLIP	23313552
MIRT684312	hsa-miR-1299	HITS-CLIP	23313552
MIRT227809	hsa-miR-4428	PAR-CLIP	20371350
MIRT227806	hsa-miR-3173-3p	PAR-CLIP	20371350
MIRT227812	hsa-miR-6891-5p	PAR-CLIP	20371350
MIRT227807	hsa-miR-4259	PAR-CLIP	20371350
MIRT563545	hsa-miR-873-5p	PAR-CLIP	20371350
MIRT563544	hsa-miR-3913-3p	PAR-CLIP	20371350
MIRT227804	hsa-miR-571	PAR-CLIP	20371350
MIRT563543	hsa-let-7d-3p	PAR-CLIP	20371350
MIRT227803	hsa-let-7e-3p	PAR-CLIP	20371350
MIRT563542	hsa-miR-489-3p	PAR-CLIP	20371350
MIRT227810	hsa-miR-4477b	PAR-CLIP	20371350
MIRT684335	hsa-miR-3646	HITS-CLIP	23313552
MIRT684334	hsa-miR-3184-3p	HITS-CLIP	23313552
MIRT684333	hsa-miR-1182	HITS-CLIP	23313552
MIRT684332	hsa-miR-1324	HITS-CLIP	23313552
MIRT043336	hsa-miR-331-3p	HITS-CLIP	23313552
MIRT684331	hsa-miR-6892-3p	HITS-CLIP	23313552
MIRT684330	hsa-miR-2276-5p	HITS-CLIP	23313552
MIRT684329	hsa-miR-4308	HITS-CLIP	23313552
MIRT684328	hsa-miR-3183	HITS-CLIP	23313552
MIRT684327	hsa-miR-4723-3p	HITS-CLIP	23313552
MIRT684326	hsa-miR-6769b-3p	HITS-CLIP	23313552
MIRT684325	hsa-miR-1304-3p	HITS-CLIP	23313552
MIRT684324	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT684323	hsa-miR-3925-3p	HITS-CLIP	23313552
MIRT684322	hsa-miR-1251-5p	HITS-CLIP	23313552
MIRT684321	hsa-miR-1199-5p	HITS-CLIP	23313552
MIRT684320	hsa-miR-6751-3p	HITS-CLIP	23313552
MIRT240700	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT684319	hsa-miR-6128	HITS-CLIP	23313552
MIRT684318	hsa-miR-494-3p	HITS-CLIP	23313552
MIRT684317	hsa-miR-6846-3p	HITS-CLIP	23313552
MIRT684316	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT684315	hsa-miR-558	HITS-CLIP	23313552
MIRT684314	hsa-miR-4487	HITS-CLIP	23313552
MIRT684313	hsa-miR-642a-5p	HITS-CLIP	23313552
MIRT684312	hsa-miR-1299	HITS-CLIP	23313552
MIRT227809	hsa-miR-4428	PAR-CLIP	20371350
MIRT227806	hsa-miR-3173-3p	PAR-CLIP	20371350
MIRT227812	hsa-miR-6891-5p	PAR-CLIP	20371350
MIRT227807	hsa-miR-4259	PAR-CLIP	20371350
MIRT563545	hsa-miR-873-5p	PAR-CLIP	20371350
MIRT563544	hsa-miR-3913-3p	PAR-CLIP	20371350
MIRT227804	hsa-miR-571	PAR-CLIP	20371350
MIRT563543	hsa-let-7d-3p	PAR-CLIP	20371350
MIRT227803	hsa-let-7e-3p	PAR-CLIP	20371350
MIRT563542	hsa-miR-489-3p	PAR-CLIP	20371350
MIRT227810	hsa-miR-4477b	PAR-CLIP	20371350
MIRT1037701	hsa-miR-1238	CLIP-seq
MIRT1037702	hsa-miR-1245b-3p	CLIP-seq
MIRT1037703	hsa-miR-146a	CLIP-seq
MIRT1037704	hsa-miR-146b-5p	CLIP-seq
MIRT1037705	hsa-miR-185	CLIP-seq
MIRT1037706	hsa-miR-25	CLIP-seq
MIRT1037707	hsa-miR-29a	CLIP-seq
MIRT1037708	hsa-miR-29b	CLIP-seq
MIRT1037709	hsa-miR-29c	CLIP-seq
MIRT1037710	hsa-miR-302f	CLIP-seq
MIRT1037711	hsa-miR-3065-3p	CLIP-seq
MIRT1037712	hsa-miR-3120-3p	CLIP-seq
MIRT1037713	hsa-miR-3166	CLIP-seq
MIRT1037714	hsa-miR-3177-5p	CLIP-seq
MIRT1037715	hsa-miR-32	CLIP-seq
MIRT1037716	hsa-miR-326	CLIP-seq
MIRT1037717	hsa-miR-330-5p	CLIP-seq
MIRT1037718	hsa-miR-363	CLIP-seq
MIRT1037719	hsa-miR-367	CLIP-seq
MIRT1037720	hsa-miR-3670	CLIP-seq
MIRT1037721	hsa-miR-4251	CLIP-seq
MIRT1037722	hsa-miR-4303	CLIP-seq
MIRT1037723	hsa-miR-4306	CLIP-seq
MIRT1037724	hsa-miR-4307	CLIP-seq
MIRT1037725	hsa-miR-4329	CLIP-seq
MIRT1037726	hsa-miR-4474-5p	CLIP-seq
MIRT1037727	hsa-miR-4496	CLIP-seq
MIRT1037728	hsa-miR-4530	CLIP-seq
MIRT1037729	hsa-miR-4644	CLIP-seq
MIRT1037730	hsa-miR-4685-5p	CLIP-seq
MIRT1037731	hsa-miR-4693-3p	CLIP-seq
MIRT1037732	hsa-miR-4694-3p	CLIP-seq
MIRT1037733	hsa-miR-4762-3p	CLIP-seq
MIRT1037734	hsa-miR-4771	CLIP-seq
MIRT1037735	hsa-miR-4782-5p	CLIP-seq
MIRT1037736	hsa-miR-489	CLIP-seq
MIRT1037737	hsa-miR-501-5p	CLIP-seq
MIRT1037738	hsa-miR-514	CLIP-seq
MIRT1037739	hsa-miR-514b-3p	CLIP-seq
MIRT1037740	hsa-miR-516b	CLIP-seq
MIRT1037741	hsa-miR-556-5p	CLIP-seq
MIRT1037742	hsa-miR-579	CLIP-seq
MIRT1037743	hsa-miR-586	CLIP-seq
MIRT1037744	hsa-miR-587	CLIP-seq
MIRT1037745	hsa-miR-589	CLIP-seq
MIRT1037746	hsa-miR-590-3p	CLIP-seq
MIRT1037747	hsa-miR-593	CLIP-seq
MIRT1037748	hsa-miR-600	CLIP-seq
MIRT1037749	hsa-miR-634	CLIP-seq
MIRT1037750	hsa-miR-642b	CLIP-seq
MIRT1037751	hsa-miR-645	CLIP-seq
MIRT1037752	hsa-miR-646	CLIP-seq
MIRT1037753	hsa-miR-651	CLIP-seq
MIRT1037754	hsa-miR-92a	CLIP-seq
MIRT1037755	hsa-miR-92b	CLIP-seq
MIRT2007606	hsa-miR-101	CLIP-seq
MIRT2007607	hsa-miR-1236	CLIP-seq
MIRT2007608	hsa-miR-139-5p	CLIP-seq
MIRT2007609	hsa-miR-144	CLIP-seq
MIRT1037706	hsa-miR-25	CLIP-seq
MIRT2007610	hsa-miR-2682	CLIP-seq
MIRT1037710	hsa-miR-302f	CLIP-seq
MIRT2007611	hsa-miR-3135b	CLIP-seq
MIRT2007612	hsa-miR-3155	CLIP-seq
MIRT2007613	hsa-miR-3155b	CLIP-seq
MIRT2007614	hsa-miR-3182	CLIP-seq
MIRT1037715	hsa-miR-32	CLIP-seq
MIRT2007615	hsa-miR-324-5p	CLIP-seq
MIRT1037718	hsa-miR-363	CLIP-seq
MIRT2007616	hsa-miR-3652	CLIP-seq
MIRT2007617	hsa-miR-3653	CLIP-seq
MIRT2007618	hsa-miR-3658	CLIP-seq
MIRT1037719	hsa-miR-367	CLIP-seq
MIRT1037720	hsa-miR-3670	CLIP-seq
MIRT2007619	hsa-miR-3671	CLIP-seq
MIRT2007620	hsa-miR-3977	CLIP-seq
MIRT1037722	hsa-miR-4303	CLIP-seq
MIRT2007621	hsa-miR-4430	CLIP-seq
MIRT1037726	hsa-miR-4474-5p	CLIP-seq
MIRT2007622	hsa-miR-449c	CLIP-seq
MIRT2007623	hsa-miR-4705	CLIP-seq
MIRT2007624	hsa-miR-4753-3p	CLIP-seq
MIRT2007625	hsa-miR-484	CLIP-seq
MIRT1037736	hsa-miR-489	CLIP-seq
MIRT2007626	hsa-miR-494	CLIP-seq
MIRT2007627	hsa-miR-505	CLIP-seq
MIRT1037738	hsa-miR-514	CLIP-seq
MIRT1037739	hsa-miR-514b-3p	CLIP-seq
MIRT1037746	hsa-miR-590-3p	CLIP-seq
MIRT2007628	hsa-miR-607	CLIP-seq
MIRT1037750	hsa-miR-642b	CLIP-seq
MIRT1037751	hsa-miR-645	CLIP-seq
MIRT2007629	hsa-miR-760	CLIP-seq
MIRT2007630	hsa-miR-765	CLIP-seq
MIRT2007631	hsa-miR-766	CLIP-seq
MIRT2007632	hsa-miR-892a	CLIP-seq
MIRT1037754	hsa-miR-92a	CLIP-seq
MIRT1037755	hsa-miR-92b	CLIP-seq
MIRT2007633	hsa-miR-942	CLIP-seq
MIRT2007606	hsa-miR-101	CLIP-seq
MIRT2240207	hsa-miR-1226	CLIP-seq
MIRT2007607	hsa-miR-1236	CLIP-seq
MIRT2240208	hsa-miR-1237	CLIP-seq
MIRT1037701	hsa-miR-1238	CLIP-seq
MIRT1037702	hsa-miR-1245b-3p	CLIP-seq
MIRT2240209	hsa-miR-1247	CLIP-seq
MIRT2240210	hsa-miR-1248	CLIP-seq
MIRT2240211	hsa-miR-1262	CLIP-seq
MIRT2240212	hsa-miR-1264	CLIP-seq
MIRT2240213	hsa-miR-1275	CLIP-seq
MIRT2240214	hsa-miR-1293	CLIP-seq
MIRT2007608	hsa-miR-139-5p	CLIP-seq
MIRT2240215	hsa-miR-140-3p	CLIP-seq
MIRT2007609	hsa-miR-144	CLIP-seq
MIRT1037703	hsa-miR-146a	CLIP-seq
MIRT1037704	hsa-miR-146b-5p	CLIP-seq
MIRT2240216	hsa-miR-183	CLIP-seq
MIRT1037705	hsa-miR-185	CLIP-seq
MIRT2240217	hsa-miR-1915	CLIP-seq
MIRT2240218	hsa-miR-224	CLIP-seq
MIRT2240219	hsa-miR-2467-3p	CLIP-seq
MIRT1037706	hsa-miR-25	CLIP-seq
MIRT2007610	hsa-miR-2682	CLIP-seq
MIRT1037707	hsa-miR-29a	CLIP-seq
MIRT1037708	hsa-miR-29b	CLIP-seq
MIRT1037709	hsa-miR-29c	CLIP-seq
MIRT1037710	hsa-miR-302f	CLIP-seq
MIRT1037711	hsa-miR-3065-3p	CLIP-seq
MIRT1037712	hsa-miR-3120-3p	CLIP-seq
MIRT2240220	hsa-miR-3123	CLIP-seq
MIRT2240221	hsa-miR-3125	CLIP-seq
MIRT2240222	hsa-miR-3132	CLIP-seq
MIRT2007611	hsa-miR-3135b	CLIP-seq
MIRT2007612	hsa-miR-3155	CLIP-seq
MIRT2007613	hsa-miR-3155b	CLIP-seq
MIRT1037713	hsa-miR-3166	CLIP-seq
MIRT1037714	hsa-miR-3177-5p	CLIP-seq
MIRT2240223	hsa-miR-3199	CLIP-seq
MIRT1037715	hsa-miR-32	CLIP-seq
MIRT2240224	hsa-miR-3200-5p	CLIP-seq
MIRT2007615	hsa-miR-324-5p	CLIP-seq
MIRT1037716	hsa-miR-326	CLIP-seq
MIRT1037717	hsa-miR-330-5p	CLIP-seq
MIRT1037718	hsa-miR-363	CLIP-seq
MIRT2007616	hsa-miR-3652	CLIP-seq
MIRT1037719	hsa-miR-367	CLIP-seq
MIRT1037720	hsa-miR-3670	CLIP-seq
MIRT2007619	hsa-miR-3671	CLIP-seq
MIRT2240225	hsa-miR-3678-3p	CLIP-seq
MIRT2240226	hsa-miR-369-3p	CLIP-seq
MIRT2240227	hsa-miR-3714	CLIP-seq
MIRT2240228	hsa-miR-374a	CLIP-seq
MIRT2240229	hsa-miR-374b	CLIP-seq
MIRT2240230	hsa-miR-3916	CLIP-seq
MIRT2240231	hsa-miR-3920	CLIP-seq
MIRT2240232	hsa-miR-3944-5p	CLIP-seq
MIRT1037721	hsa-miR-4251	CLIP-seq
MIRT1037722	hsa-miR-4303	CLIP-seq
MIRT1037723	hsa-miR-4306	CLIP-seq
MIRT1037724	hsa-miR-4307	CLIP-seq
MIRT2240233	hsa-miR-4320	CLIP-seq
MIRT1037725	hsa-miR-4329	CLIP-seq
MIRT2240234	hsa-miR-4420	CLIP-seq
MIRT2007621	hsa-miR-4430	CLIP-seq
MIRT1037726	hsa-miR-4474-5p	CLIP-seq
MIRT2240235	hsa-miR-4475	CLIP-seq
MIRT2240236	hsa-miR-4483	CLIP-seq
MIRT2240237	hsa-miR-4488	CLIP-seq
MIRT1037727	hsa-miR-4496	CLIP-seq
MIRT2007622	hsa-miR-449c	CLIP-seq
MIRT2240238	hsa-miR-4528	CLIP-seq
MIRT1037728	hsa-miR-4530	CLIP-seq
MIRT2240239	hsa-miR-4636	CLIP-seq
MIRT2240240	hsa-miR-4641	CLIP-seq
MIRT1037729	hsa-miR-4644	CLIP-seq
MIRT2240241	hsa-miR-4665-5p	CLIP-seq
MIRT2240242	hsa-miR-4682	CLIP-seq
MIRT1037730	hsa-miR-4685-5p	CLIP-seq
MIRT2240243	hsa-miR-4690-3p	CLIP-seq
MIRT1037731	hsa-miR-4693-3p	CLIP-seq
MIRT1037732	hsa-miR-4694-3p	CLIP-seq
MIRT2240244	hsa-miR-4697-5p	CLIP-seq
MIRT2240245	hsa-miR-4701-3p	CLIP-seq
MIRT2007623	hsa-miR-4705	CLIP-seq
MIRT2240246	hsa-miR-4726-3p	CLIP-seq
MIRT2240247	hsa-miR-4733-3p	CLIP-seq
MIRT2007624	hsa-miR-4753-3p	CLIP-seq
MIRT1037733	hsa-miR-4762-3p	CLIP-seq
MIRT2240248	hsa-miR-4768-3p	CLIP-seq
MIRT2240249	hsa-miR-4768-5p	CLIP-seq
MIRT1037734	hsa-miR-4771	CLIP-seq
MIRT1037735	hsa-miR-4782-5p	CLIP-seq
MIRT2007625	hsa-miR-484	CLIP-seq
MIRT2240250	hsa-miR-486-3p	CLIP-seq
MIRT1037736	hsa-miR-489	CLIP-seq
MIRT2240251	hsa-miR-490-3p	CLIP-seq
MIRT2007626	hsa-miR-494	CLIP-seq
MIRT1037737	hsa-miR-501-5p	CLIP-seq
MIRT2007627	hsa-miR-505	CLIP-seq
MIRT1037738	hsa-miR-514	CLIP-seq
MIRT1037739	hsa-miR-514b-3p	CLIP-seq
MIRT1037740	hsa-miR-516b	CLIP-seq
MIRT1037741	hsa-miR-556-5p	CLIP-seq
MIRT1037742	hsa-miR-579	CLIP-seq
MIRT1037743	hsa-miR-586	CLIP-seq
MIRT1037744	hsa-miR-587	CLIP-seq
MIRT1037745	hsa-miR-589	CLIP-seq
MIRT1037746	hsa-miR-590-3p	CLIP-seq
MIRT1037747	hsa-miR-593	CLIP-seq
MIRT1037748	hsa-miR-600	CLIP-seq
MIRT2007628	hsa-miR-607	CLIP-seq
MIRT2240252	hsa-miR-619	CLIP-seq
MIRT2240253	hsa-miR-633	CLIP-seq
MIRT1037749	hsa-miR-634	CLIP-seq
MIRT1037750	hsa-miR-642b	CLIP-seq
MIRT1037751	hsa-miR-645	CLIP-seq
MIRT1037752	hsa-miR-646	CLIP-seq
MIRT2240254	hsa-miR-664	CLIP-seq
MIRT2240255	hsa-miR-665	CLIP-seq
MIRT2007629	hsa-miR-760	CLIP-seq
MIRT2007630	hsa-miR-765	CLIP-seq
MIRT2240256	hsa-miR-873	CLIP-seq
MIRT2007632	hsa-miR-892a	CLIP-seq
MIRT1037754	hsa-miR-92a	CLIP-seq
MIRT1037755	hsa-miR-92b	CLIP-seq
MIRT2240257	hsa-miR-938	CLIP-seq
MIRT2007633	hsa-miR-942	CLIP-seq
MIRT2240258	hsa-miR-944	CLIP-seq
MIRT1037750	hsa-miR-642b	CLIP-seq
MIRT2007631	hsa-miR-766	CLIP-seq
MIRT2240213	hsa-miR-1275	CLIP-seq
MIRT2240214	hsa-miR-1293	CLIP-seq
MIRT1037710	hsa-miR-302f	CLIP-seq
MIRT2240222	hsa-miR-3132	CLIP-seq
MIRT2007614	hsa-miR-3182	CLIP-seq
MIRT2007619	hsa-miR-3671	CLIP-seq
MIRT2007620	hsa-miR-3977	CLIP-seq
MIRT1037724	hsa-miR-4307	CLIP-seq
MIRT2240236	hsa-miR-4483	CLIP-seq
MIRT2240237	hsa-miR-4488	CLIP-seq
MIRT1037727	hsa-miR-4496	CLIP-seq
MIRT2240241	hsa-miR-4665-5p	CLIP-seq
MIRT2240244	hsa-miR-4697-5p	CLIP-seq
MIRT2240250	hsa-miR-486-3p	CLIP-seq
MIRT1037743	hsa-miR-586	CLIP-seq
MIRT1037744	hsa-miR-587	CLIP-seq
MIRT2007628	hsa-miR-607	CLIP-seq
MIRT2007632	hsa-miR-892a	CLIP-seq
MIRT1037710	hsa-miR-302f	CLIP-seq
MIRT2007614	hsa-miR-3182	CLIP-seq
MIRT2682192	hsa-miR-3189-5p	CLIP-seq
MIRT2240224	hsa-miR-3200-5p	CLIP-seq
MIRT2007619	hsa-miR-3671	CLIP-seq
MIRT2007620	hsa-miR-3977	CLIP-seq
MIRT1037721	hsa-miR-4251	CLIP-seq
MIRT2682193	hsa-miR-4323	CLIP-seq
MIRT1037725	hsa-miR-4329	CLIP-seq
MIRT2007628	hsa-miR-607	CLIP-seq
MIRT2007632	hsa-miR-892a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000127	Component	Transcription factor TFIIIC complex	IBA
GO:0000127	Component	Transcription factor TFIIIC complex	IDA	17409385
GO:0000127	Component	Transcription factor TFIIIC complex	IEA
GO:0000995	Function	RNA polymerase III general transcription initiation factor activity	IDA	17409385
GO:0003677	Function	DNA binding	IC	17409385
GO:0003677	Function	DNA binding	IEA
GO:0004402	Function	Histone acetyltransferase activity	IEA
GO:0005515	Function	Protein binding	IPI	17409385, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005739	Component	Mitochondrion	IDA
GO:0006338	Process	Chromatin remodeling	IEA
GO:0006383	Process	Transcription by RNA polymerase III	IC	17409385
GO:0006384	Process	Transcription initiation at RNA polymerase III promoter	IEA
GO:0006384	Process	Transcription initiation at RNA polymerase III promoter	TAS	10523658
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0036408	Function	Histone H3K14 acetyltransferase activity	IDA	10523658
GO:0042791	Process	5S class rRNA transcription by RNA polymerase III	IC	17409385
GO:0042797	Process	TRNA transcription by RNA polymerase III	IC	17409385
GO:0061733	Function	Protein-lysine-acetyltransferase activity	IEA

Other IDs

• MIM: 604892
• HGNC: 4667
• e!Ensembl: ENSG00000125484

Protein

• UniProt ID: Q9UKN8
• Protein name: General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta)
• Protein function: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin (PubMed:10523658). Has histone acetyltransferase activity (HAT)
• PDB: 8CLI, 8CLJ, 8CLL
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12657	TFIIIC_delta	63 → 254	Transcription factor IIIC subunit delta N-term	Domain
  PF12660	zf-TFIIIC	733 → 821	Putative zinc-finger of transcription factor IIIC complex	Domain

• Sequence:

  MNTADQARVGPADDGPAPSGEEEGEGGGEAGGKEPAADAAPGPSAAFRLMVTRREPAVKL
  QYAVSGLEPLAWSEDHRVSVSTARSIAVLELICDVHNPGQDLVIHRTSVPAPLNSCLLKV
  GSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYTSWSPMGCDANGRC
  LLAALTMDNRLTIQANLNRLQWVQLVDLTEIYGERLYETSYRLSKNEAPEGNLGDFAEFQ
  RRHSMQTPVRMEWSGICTTQQVKHNNECRDVGSVLLAVLFENGNIAVWQFQLPFVGKESI
  SSCNTIESGITSPSVLFWWEYEHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLRQPV
  ILWKEMDQLPVHSIKCVPLYHPYQKCSCSLVVAARGSYVFWCLLLISKAGLNVHNSHVTG
  LHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLIKLSDVFGSVRTHGI
  AVSPCGAYLAIITTEGMINGLHPVNKNYQVQFVTLKTFEEAAAQLLESSVQNLFKQVDLI
  DLVRWKILKDKHIPQFLQEALEKKIESSGVTYFWRFKLFLLRILYQSMQKTPSEALWKPT
  HEDSKILLVDSPGMGNADDEQQEEGTSSKQVVKQGLQERSKEGDVEEPTDDSLPTTGDAG
  GREPMEEKLLEIQGKIEAVEMHLTREHMKRVLGEVYLHTWITENTSIPTRGLCNFLMSDE
  EYDDRTARVLIGHISKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSC
  QSLIYRRCLLHDSIARHPAPEDPDWIKRLLQSPCPFCDSPVF

• Sequence length: 822

Pathways

Reactome:

RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Neoplasms	Breast neoplasm	Pubtator	33617509	Associate	★☆☆☆☆ Found in Text Mining only