COPS2 (COP9 signalosome subunit 2)

Gene

• Entrez ID: 9318
• Gene name: COP9 signalosome subunit 2
• Gene symbol: COPS2
• Synonyms (NCBI Gene): ALIEN, CSN2, SGN2, TRIP15
• Chromosome: 15
• Chromosome location: 15q21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025181	hsa-miR-181a-5p	Microarray	17612493
MIRT032402	hsa-let-7b-5p	Proteomics	18668040
MIRT440910	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440910	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT903898	hsa-miR-106a	CLIP-seq
MIRT903899	hsa-miR-106b	CLIP-seq
MIRT903900	hsa-miR-1244	CLIP-seq
MIRT903901	hsa-miR-1283	CLIP-seq
MIRT903902	hsa-miR-1297	CLIP-seq
MIRT903903	hsa-miR-1305	CLIP-seq
MIRT903904	hsa-miR-137	CLIP-seq
MIRT903905	hsa-miR-154	CLIP-seq
MIRT903906	hsa-miR-17	CLIP-seq
MIRT903907	hsa-miR-181a	CLIP-seq
MIRT903908	hsa-miR-181b	CLIP-seq
MIRT903909	hsa-miR-181c	CLIP-seq
MIRT903910	hsa-miR-181d	CLIP-seq
MIRT903911	hsa-miR-2052	CLIP-seq
MIRT903912	hsa-miR-20a	CLIP-seq
MIRT903913	hsa-miR-20b	CLIP-seq
MIRT903914	hsa-miR-2467-3p	CLIP-seq
MIRT903915	hsa-miR-25	CLIP-seq
MIRT903916	hsa-miR-26a	CLIP-seq
MIRT903917	hsa-miR-26b	CLIP-seq
MIRT903918	hsa-miR-3115	CLIP-seq
MIRT903919	hsa-miR-3122	CLIP-seq
MIRT903920	hsa-miR-3128	CLIP-seq
MIRT903921	hsa-miR-3143	CLIP-seq
MIRT903922	hsa-miR-3168	CLIP-seq
MIRT903923	hsa-miR-3170	CLIP-seq
MIRT903924	hsa-miR-32	CLIP-seq
MIRT903925	hsa-miR-338-3p	CLIP-seq
MIRT903926	hsa-miR-338-5p	CLIP-seq
MIRT903927	hsa-miR-34c-3p	CLIP-seq
MIRT903928	hsa-miR-3609	CLIP-seq
MIRT903929	hsa-miR-363	CLIP-seq
MIRT903930	hsa-miR-3665	CLIP-seq
MIRT903931	hsa-miR-367	CLIP-seq
MIRT903932	hsa-miR-3675-5p	CLIP-seq
MIRT903933	hsa-miR-3676	CLIP-seq
MIRT903934	hsa-miR-3678-3p	CLIP-seq
MIRT903935	hsa-miR-3913-5p	CLIP-seq
MIRT903936	hsa-miR-4251	CLIP-seq
MIRT903937	hsa-miR-4252	CLIP-seq
MIRT903938	hsa-miR-4255	CLIP-seq
MIRT903939	hsa-miR-4262	CLIP-seq
MIRT903940	hsa-miR-4297	CLIP-seq
MIRT903941	hsa-miR-4303	CLIP-seq
MIRT903942	hsa-miR-4329	CLIP-seq
MIRT903943	hsa-miR-4465	CLIP-seq
MIRT903944	hsa-miR-4496	CLIP-seq
MIRT903945	hsa-miR-450b-3p	CLIP-seq
MIRT903946	hsa-miR-4530	CLIP-seq
MIRT903947	hsa-miR-4693-3p	CLIP-seq
MIRT903948	hsa-miR-4720-5p	CLIP-seq
MIRT903949	hsa-miR-4729	CLIP-seq
MIRT903950	hsa-miR-4796-3p	CLIP-seq
MIRT903951	hsa-miR-4796-5p	CLIP-seq
MIRT903952	hsa-miR-4799-3p	CLIP-seq
MIRT903953	hsa-miR-498	CLIP-seq
MIRT903954	hsa-miR-519d	CLIP-seq
MIRT903955	hsa-miR-539	CLIP-seq
MIRT903956	hsa-miR-543	CLIP-seq
MIRT903957	hsa-miR-548a-3p	CLIP-seq
MIRT903958	hsa-miR-548ah	CLIP-seq
MIRT903959	hsa-miR-548e	CLIP-seq
MIRT903960	hsa-miR-548f	CLIP-seq
MIRT903961	hsa-miR-579	CLIP-seq
MIRT903962	hsa-miR-586	CLIP-seq
MIRT903963	hsa-miR-618	CLIP-seq
MIRT903964	hsa-miR-626	CLIP-seq
MIRT903965	hsa-miR-630	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT903967	hsa-miR-664	CLIP-seq
MIRT903968	hsa-miR-769-3p	CLIP-seq
MIRT903969	hsa-miR-802	CLIP-seq
MIRT903970	hsa-miR-92a	CLIP-seq
MIRT903971	hsa-miR-92b	CLIP-seq
MIRT903972	hsa-miR-93	CLIP-seq
MIRT903973	hsa-miR-944	CLIP-seq
MIRT903974	hsa-miR-103a	CLIP-seq
MIRT903898	hsa-miR-106a	CLIP-seq
MIRT903899	hsa-miR-106b	CLIP-seq
MIRT903975	hsa-miR-107	CLIP-seq
MIRT903976	hsa-miR-1184	CLIP-seq
MIRT903977	hsa-miR-1205	CLIP-seq
MIRT903978	hsa-miR-1237	CLIP-seq
MIRT903979	hsa-miR-1248	CLIP-seq
MIRT903902	hsa-miR-1297	CLIP-seq
MIRT903904	hsa-miR-137	CLIP-seq
MIRT903905	hsa-miR-154	CLIP-seq
MIRT903980	hsa-miR-15a	CLIP-seq
MIRT903981	hsa-miR-15b	CLIP-seq
MIRT903982	hsa-miR-16	CLIP-seq
MIRT903906	hsa-miR-17	CLIP-seq
MIRT903907	hsa-miR-181a	CLIP-seq
MIRT903908	hsa-miR-181b	CLIP-seq
MIRT903909	hsa-miR-181c	CLIP-seq
MIRT903910	hsa-miR-181d	CLIP-seq
MIRT903983	hsa-miR-195	CLIP-seq
MIRT903984	hsa-miR-200b	CLIP-seq
MIRT903985	hsa-miR-200c	CLIP-seq
MIRT903986	hsa-miR-2054	CLIP-seq
MIRT903912	hsa-miR-20a	CLIP-seq
MIRT903913	hsa-miR-20b	CLIP-seq
MIRT903914	hsa-miR-2467-3p	CLIP-seq
MIRT903915	hsa-miR-25	CLIP-seq
MIRT903916	hsa-miR-26a	CLIP-seq
MIRT903917	hsa-miR-26b	CLIP-seq
MIRT903987	hsa-miR-30a	CLIP-seq
MIRT903988	hsa-miR-30b	CLIP-seq
MIRT903989	hsa-miR-30c	CLIP-seq
MIRT903990	hsa-miR-30d	CLIP-seq
MIRT903991	hsa-miR-30e	CLIP-seq
MIRT903992	hsa-miR-3123	CLIP-seq
MIRT903993	hsa-miR-3126-3p	CLIP-seq
MIRT903920	hsa-miR-3128	CLIP-seq
MIRT903994	hsa-miR-3129-3p	CLIP-seq
MIRT903995	hsa-miR-3130-5p	CLIP-seq
MIRT903996	hsa-miR-3133	CLIP-seq
MIRT903921	hsa-miR-3143	CLIP-seq
MIRT903997	hsa-miR-3158-5p	CLIP-seq
MIRT903924	hsa-miR-32	CLIP-seq
MIRT903998	hsa-miR-330-3p	CLIP-seq
MIRT903925	hsa-miR-338-3p	CLIP-seq
MIRT903926	hsa-miR-338-5p	CLIP-seq
MIRT903927	hsa-miR-34c-3p	CLIP-seq
MIRT903999	hsa-miR-3545-3p	CLIP-seq
MIRT903928	hsa-miR-3609	CLIP-seq
MIRT904000	hsa-miR-3613-3p	CLIP-seq
MIRT903929	hsa-miR-363	CLIP-seq
MIRT903930	hsa-miR-3665	CLIP-seq
MIRT903931	hsa-miR-367	CLIP-seq
MIRT903934	hsa-miR-3678-3p	CLIP-seq
MIRT904001	hsa-miR-3688-5p	CLIP-seq
MIRT904002	hsa-miR-374c	CLIP-seq
MIRT904003	hsa-miR-380	CLIP-seq
MIRT904004	hsa-miR-411	CLIP-seq
MIRT904005	hsa-miR-424	CLIP-seq
MIRT903936	hsa-miR-4251	CLIP-seq
MIRT903939	hsa-miR-4262	CLIP-seq
MIRT904006	hsa-miR-4275	CLIP-seq
MIRT904007	hsa-miR-429	CLIP-seq
MIRT903941	hsa-miR-4303	CLIP-seq
MIRT903942	hsa-miR-4329	CLIP-seq
MIRT903943	hsa-miR-4465	CLIP-seq
MIRT904008	hsa-miR-4474-3p	CLIP-seq
MIRT904009	hsa-miR-4482	CLIP-seq
MIRT904010	hsa-miR-4495	CLIP-seq
MIRT903944	hsa-miR-4496	CLIP-seq
MIRT903945	hsa-miR-450b-3p	CLIP-seq
MIRT903946	hsa-miR-4530	CLIP-seq
MIRT904011	hsa-miR-4539	CLIP-seq
MIRT904012	hsa-miR-4662a-3p	CLIP-seq
MIRT903947	hsa-miR-4693-3p	CLIP-seq
MIRT904013	hsa-miR-4709-5p	CLIP-seq
MIRT904014	hsa-miR-4715-3p	CLIP-seq
MIRT903948	hsa-miR-4720-5p	CLIP-seq
MIRT903949	hsa-miR-4729	CLIP-seq
MIRT904015	hsa-miR-4731-3p	CLIP-seq
MIRT903950	hsa-miR-4796-3p	CLIP-seq
MIRT903951	hsa-miR-4796-5p	CLIP-seq
MIRT903952	hsa-miR-4799-3p	CLIP-seq
MIRT904016	hsa-miR-4801	CLIP-seq
MIRT904017	hsa-miR-497	CLIP-seq
MIRT903953	hsa-miR-498	CLIP-seq
MIRT904018	hsa-miR-513a-3p	CLIP-seq
MIRT904019	hsa-miR-516a-3p	CLIP-seq
MIRT903954	hsa-miR-519d	CLIP-seq
MIRT904020	hsa-miR-520d-5p	CLIP-seq
MIRT904021	hsa-miR-524-5p	CLIP-seq
MIRT903956	hsa-miR-543	CLIP-seq
MIRT904022	hsa-miR-544	CLIP-seq
MIRT904023	hsa-miR-545	CLIP-seq
MIRT903958	hsa-miR-548ah	CLIP-seq
MIRT904024	hsa-miR-548c-3p	CLIP-seq
MIRT904025	hsa-miR-548p	CLIP-seq
MIRT904026	hsa-miR-555	CLIP-seq
MIRT904027	hsa-miR-578	CLIP-seq
MIRT903961	hsa-miR-579	CLIP-seq
MIRT903962	hsa-miR-586	CLIP-seq
MIRT904028	hsa-miR-605	CLIP-seq
MIRT903964	hsa-miR-626	CLIP-seq
MIRT904029	hsa-miR-635	CLIP-seq
MIRT904030	hsa-miR-655	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT904031	hsa-miR-659	CLIP-seq
MIRT903967	hsa-miR-664	CLIP-seq
MIRT904032	hsa-miR-758	CLIP-seq
MIRT903968	hsa-miR-769-3p	CLIP-seq
MIRT903969	hsa-miR-802	CLIP-seq
MIRT904033	hsa-miR-885-3p	CLIP-seq
MIRT903970	hsa-miR-92a	CLIP-seq
MIRT903971	hsa-miR-92b	CLIP-seq
MIRT903972	hsa-miR-93	CLIP-seq
MIRT903961	hsa-miR-579	CLIP-seq
MIRT903907	hsa-miR-181a	CLIP-seq
MIRT903908	hsa-miR-181b	CLIP-seq
MIRT903909	hsa-miR-181c	CLIP-seq
MIRT903910	hsa-miR-181d	CLIP-seq
MIRT903914	hsa-miR-2467-3p	CLIP-seq
MIRT903920	hsa-miR-3128	CLIP-seq
MIRT903921	hsa-miR-3143	CLIP-seq
MIRT903934	hsa-miR-3678-3p	CLIP-seq
MIRT903939	hsa-miR-4262	CLIP-seq
MIRT903948	hsa-miR-4720-5p	CLIP-seq
MIRT903949	hsa-miR-4729	CLIP-seq
MIRT903951	hsa-miR-4796-5p	CLIP-seq
MIRT903952	hsa-miR-4799-3p	CLIP-seq
MIRT903956	hsa-miR-543	CLIP-seq
MIRT903961	hsa-miR-579	CLIP-seq
MIRT903964	hsa-miR-626	CLIP-seq
MIRT903967	hsa-miR-664	CLIP-seq
MIRT903969	hsa-miR-802	CLIP-seq
MIRT904000	hsa-miR-3613-3p	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT1968020	hsa-miR-1272	CLIP-seq
MIRT1968021	hsa-miR-1322	CLIP-seq
MIRT1968022	hsa-miR-3973	CLIP-seq
MIRT903937	hsa-miR-4252	CLIP-seq
MIRT1968023	hsa-miR-4477b	CLIP-seq
MIRT903948	hsa-miR-4720-5p	CLIP-seq
MIRT1968024	hsa-miR-4775	CLIP-seq
MIRT1968025	hsa-miR-4789-5p	CLIP-seq
MIRT903952	hsa-miR-4799-3p	CLIP-seq
MIRT903953	hsa-miR-498	CLIP-seq
MIRT1968026	hsa-miR-520g	CLIP-seq
MIRT1968027	hsa-miR-520h	CLIP-seq
MIRT903955	hsa-miR-539	CLIP-seq
MIRT903956	hsa-miR-543	CLIP-seq
MIRT904024	hsa-miR-548c-3p	CLIP-seq
MIRT903898	hsa-miR-106a	CLIP-seq
MIRT903899	hsa-miR-106b	CLIP-seq
MIRT903976	hsa-miR-1184	CLIP-seq
MIRT2203884	hsa-miR-1197	CLIP-seq
MIRT903977	hsa-miR-1205	CLIP-seq
MIRT2203885	hsa-miR-1208	CLIP-seq
MIRT903901	hsa-miR-1283	CLIP-seq
MIRT903902	hsa-miR-1297	CLIP-seq
MIRT2203886	hsa-miR-1303	CLIP-seq
MIRT903905	hsa-miR-154	CLIP-seq
MIRT903906	hsa-miR-17	CLIP-seq
MIRT903907	hsa-miR-181a	CLIP-seq
MIRT903908	hsa-miR-181b	CLIP-seq
MIRT903909	hsa-miR-181c	CLIP-seq
MIRT903910	hsa-miR-181d	CLIP-seq
MIRT903984	hsa-miR-200b	CLIP-seq
MIRT903985	hsa-miR-200c	CLIP-seq
MIRT903912	hsa-miR-20a	CLIP-seq
MIRT903913	hsa-miR-20b	CLIP-seq
MIRT903914	hsa-miR-2467-3p	CLIP-seq
MIRT903916	hsa-miR-26a	CLIP-seq
MIRT903917	hsa-miR-26b	CLIP-seq
MIRT2203887	hsa-miR-3120-3p	CLIP-seq
MIRT903992	hsa-miR-3123	CLIP-seq
MIRT903920	hsa-miR-3128	CLIP-seq
MIRT903921	hsa-miR-3143	CLIP-seq
MIRT903997	hsa-miR-3158-5p	CLIP-seq
MIRT2203888	hsa-miR-3182	CLIP-seq
MIRT2203889	hsa-miR-326	CLIP-seq
MIRT2203890	hsa-miR-330-5p	CLIP-seq
MIRT903925	hsa-miR-338-3p	CLIP-seq
MIRT903927	hsa-miR-34c-3p	CLIP-seq
MIRT2203891	hsa-miR-3607-3p	CLIP-seq
MIRT903928	hsa-miR-3609	CLIP-seq
MIRT904000	hsa-miR-3613-3p	CLIP-seq
MIRT903930	hsa-miR-3665	CLIP-seq
MIRT903934	hsa-miR-3678-3p	CLIP-seq
MIRT2203892	hsa-miR-3686	CLIP-seq
MIRT2203893	hsa-miR-371b-5p	CLIP-seq
MIRT2203894	hsa-miR-3925-5p	CLIP-seq
MIRT903936	hsa-miR-4251	CLIP-seq
MIRT903937	hsa-miR-4252	CLIP-seq
MIRT903939	hsa-miR-4262	CLIP-seq
MIRT904007	hsa-miR-429	CLIP-seq
MIRT903941	hsa-miR-4303	CLIP-seq
MIRT903942	hsa-miR-4329	CLIP-seq
MIRT2203895	hsa-miR-4436a	CLIP-seq
MIRT903943	hsa-miR-4465	CLIP-seq
MIRT1968023	hsa-miR-4477b	CLIP-seq
MIRT2203896	hsa-miR-4480	CLIP-seq
MIRT2203897	hsa-miR-450b-5p	CLIP-seq
MIRT2203898	hsa-miR-452	CLIP-seq
MIRT903946	hsa-miR-4530	CLIP-seq
MIRT2203899	hsa-miR-4645-3p	CLIP-seq
MIRT2203900	hsa-miR-4668-3p	CLIP-seq
MIRT2203901	hsa-miR-4676-3p	CLIP-seq
MIRT903947	hsa-miR-4693-3p	CLIP-seq
MIRT2203902	hsa-miR-4698	CLIP-seq
MIRT903948	hsa-miR-4720-5p	CLIP-seq
MIRT903949	hsa-miR-4729	CLIP-seq
MIRT2203903	hsa-miR-4768-5p	CLIP-seq
MIRT1968024	hsa-miR-4775	CLIP-seq
MIRT2203904	hsa-miR-4793-3p	CLIP-seq
MIRT903950	hsa-miR-4796-3p	CLIP-seq
MIRT903951	hsa-miR-4796-5p	CLIP-seq
MIRT903952	hsa-miR-4799-3p	CLIP-seq
MIRT2203905	hsa-miR-489	CLIP-seq
MIRT903953	hsa-miR-498	CLIP-seq
MIRT2203906	hsa-miR-507	CLIP-seq
MIRT904019	hsa-miR-516a-3p	CLIP-seq
MIRT2203907	hsa-miR-518a-5p	CLIP-seq
MIRT903954	hsa-miR-519d	CLIP-seq
MIRT2203908	hsa-miR-527	CLIP-seq
MIRT903956	hsa-miR-543	CLIP-seq
MIRT904022	hsa-miR-544	CLIP-seq
MIRT2203909	hsa-miR-548ac	CLIP-seq
MIRT903958	hsa-miR-548ah	CLIP-seq
MIRT904024	hsa-miR-548c-3p	CLIP-seq
MIRT2203910	hsa-miR-548d-3p	CLIP-seq
MIRT2203911	hsa-miR-548z	CLIP-seq
MIRT2203912	hsa-miR-557	CLIP-seq
MIRT2203913	hsa-miR-568	CLIP-seq
MIRT903961	hsa-miR-579	CLIP-seq
MIRT903962	hsa-miR-586	CLIP-seq
MIRT2203914	hsa-miR-590-3p	CLIP-seq
MIRT904028	hsa-miR-605	CLIP-seq
MIRT903964	hsa-miR-626	CLIP-seq
MIRT2203915	hsa-miR-642b	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT903967	hsa-miR-664	CLIP-seq
MIRT904032	hsa-miR-758	CLIP-seq
MIRT2203916	hsa-miR-767-3p	CLIP-seq
MIRT903969	hsa-miR-802	CLIP-seq
MIRT903972	hsa-miR-93	CLIP-seq
MIRT2203917	hsa-miR-942	CLIP-seq
MIRT903973	hsa-miR-944	CLIP-seq
MIRT2203885	hsa-miR-1208	CLIP-seq
MIRT904000	hsa-miR-3613-3p	CLIP-seq
MIRT904002	hsa-miR-374c	CLIP-seq
MIRT2386365	hsa-miR-4422	CLIP-seq
MIRT903956	hsa-miR-543	CLIP-seq
MIRT904030	hsa-miR-655	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT2447457	hsa-miR-548u	CLIP-seq
MIRT903974	hsa-miR-103a	CLIP-seq
MIRT903975	hsa-miR-107	CLIP-seq
MIRT2507084	hsa-miR-1182	CLIP-seq
MIRT903976	hsa-miR-1184	CLIP-seq
MIRT903977	hsa-miR-1205	CLIP-seq
MIRT2507085	hsa-miR-1261	CLIP-seq
MIRT2507086	hsa-miR-1270	CLIP-seq
MIRT1968020	hsa-miR-1272	CLIP-seq
MIRT2507087	hsa-miR-1296	CLIP-seq
MIRT903902	hsa-miR-1297	CLIP-seq
MIRT2507088	hsa-miR-1299	CLIP-seq
MIRT2203886	hsa-miR-1303	CLIP-seq
MIRT1968021	hsa-miR-1322	CLIP-seq
MIRT903904	hsa-miR-137	CLIP-seq
MIRT903905	hsa-miR-154	CLIP-seq
MIRT2507089	hsa-miR-2053	CLIP-seq
MIRT903915	hsa-miR-25	CLIP-seq
MIRT903916	hsa-miR-26a	CLIP-seq
MIRT903917	hsa-miR-26b	CLIP-seq
MIRT2507090	hsa-miR-2909	CLIP-seq
MIRT2507091	hsa-miR-31	CLIP-seq
MIRT2507092	hsa-miR-3117-5p	CLIP-seq
MIRT2203887	hsa-miR-3120-3p	CLIP-seq
MIRT903919	hsa-miR-3122	CLIP-seq
MIRT903992	hsa-miR-3123	CLIP-seq
MIRT903993	hsa-miR-3126-3p	CLIP-seq
MIRT903995	hsa-miR-3130-5p	CLIP-seq
MIRT903996	hsa-miR-3133	CLIP-seq
MIRT903997	hsa-miR-3158-5p	CLIP-seq
MIRT2507093	hsa-miR-3163	CLIP-seq
MIRT903922	hsa-miR-3168	CLIP-seq
MIRT2203888	hsa-miR-3182	CLIP-seq
MIRT903924	hsa-miR-32	CLIP-seq
MIRT2507094	hsa-miR-320a	CLIP-seq
MIRT2507095	hsa-miR-320b	CLIP-seq
MIRT2507096	hsa-miR-320c	CLIP-seq
MIRT2507097	hsa-miR-320d	CLIP-seq
MIRT903998	hsa-miR-330-3p	CLIP-seq
MIRT904000	hsa-miR-3613-3p	CLIP-seq
MIRT2507098	hsa-miR-3613-5p	CLIP-seq
MIRT903929	hsa-miR-363	CLIP-seq
MIRT903930	hsa-miR-3665	CLIP-seq
MIRT903931	hsa-miR-367	CLIP-seq
MIRT2203893	hsa-miR-371b-5p	CLIP-seq
MIRT903935	hsa-miR-3913-5p	CLIP-seq
MIRT2203894	hsa-miR-3925-5p	CLIP-seq
MIRT2507099	hsa-miR-3942-5p	CLIP-seq
MIRT903937	hsa-miR-4252	CLIP-seq
MIRT903938	hsa-miR-4255	CLIP-seq
MIRT903940	hsa-miR-4297	CLIP-seq
MIRT2507100	hsa-miR-4328	CLIP-seq
MIRT2507101	hsa-miR-4429	CLIP-seq
MIRT2507102	hsa-miR-4436b-3p	CLIP-seq
MIRT903943	hsa-miR-4465	CLIP-seq
MIRT904009	hsa-miR-4482	CLIP-seq
MIRT903945	hsa-miR-450b-3p	CLIP-seq
MIRT2203897	hsa-miR-450b-5p	CLIP-seq
MIRT2507103	hsa-miR-4659a-3p	CLIP-seq
MIRT2507104	hsa-miR-4659b-3p	CLIP-seq
MIRT2507105	hsa-miR-4683	CLIP-seq
MIRT2203902	hsa-miR-4698	CLIP-seq
MIRT2507106	hsa-miR-4703-5p	CLIP-seq
MIRT904014	hsa-miR-4715-3p	CLIP-seq
MIRT2507107	hsa-miR-4761-3p	CLIP-seq
MIRT1968024	hsa-miR-4775	CLIP-seq
MIRT2507108	hsa-miR-4782-5p	CLIP-seq
MIRT1968025	hsa-miR-4789-5p	CLIP-seq
MIRT2203905	hsa-miR-489	CLIP-seq
MIRT2507109	hsa-miR-495	CLIP-seq
MIRT903953	hsa-miR-498	CLIP-seq
MIRT2507110	hsa-miR-500a	CLIP-seq
MIRT2203906	hsa-miR-507	CLIP-seq
MIRT2507111	hsa-miR-515-5p	CLIP-seq
MIRT2507112	hsa-miR-516b	CLIP-seq
MIRT2203907	hsa-miR-518a-5p	CLIP-seq
MIRT2203908	hsa-miR-527	CLIP-seq
MIRT903955	hsa-miR-539	CLIP-seq
MIRT904022	hsa-miR-544	CLIP-seq
MIRT904023	hsa-miR-545	CLIP-seq
MIRT903957	hsa-miR-548a-3p	CLIP-seq
MIRT2507113	hsa-miR-548aa	CLIP-seq
MIRT2203909	hsa-miR-548ac	CLIP-seq
MIRT2507114	hsa-miR-548ae	CLIP-seq
MIRT2507115	hsa-miR-548aj	CLIP-seq
MIRT2507116	hsa-miR-548am	CLIP-seq
MIRT2203910	hsa-miR-548d-3p	CLIP-seq
MIRT903959	hsa-miR-548e	CLIP-seq
MIRT903960	hsa-miR-548f	CLIP-seq
MIRT2507117	hsa-miR-548x	CLIP-seq
MIRT2203911	hsa-miR-548z	CLIP-seq
MIRT904026	hsa-miR-555	CLIP-seq
MIRT2203912	hsa-miR-557	CLIP-seq
MIRT2507118	hsa-miR-569	CLIP-seq
MIRT904027	hsa-miR-578	CLIP-seq
MIRT903962	hsa-miR-586	CLIP-seq
MIRT904028	hsa-miR-605	CLIP-seq
MIRT2507119	hsa-miR-620	CLIP-seq
MIRT904029	hsa-miR-635	CLIP-seq
MIRT2203915	hsa-miR-642b	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT904031	hsa-miR-659	CLIP-seq
MIRT904032	hsa-miR-758	CLIP-seq
MIRT2203916	hsa-miR-767-3p	CLIP-seq
MIRT903968	hsa-miR-769-3p	CLIP-seq
MIRT903970	hsa-miR-92a	CLIP-seq
MIRT903971	hsa-miR-92b	CLIP-seq
MIRT903992	hsa-miR-3123	CLIP-seq
MIRT903945	hsa-miR-450b-3p	CLIP-seq
MIRT904022	hsa-miR-544	CLIP-seq
MIRT903968	hsa-miR-769-3p	CLIP-seq
MIRT903974	hsa-miR-103a	CLIP-seq
MIRT903975	hsa-miR-107	CLIP-seq
MIRT903976	hsa-miR-1184	CLIP-seq
MIRT903977	hsa-miR-1205	CLIP-seq
MIRT903900	hsa-miR-1244	CLIP-seq
MIRT2507086	hsa-miR-1270	CLIP-seq
MIRT1968020	hsa-miR-1272	CLIP-seq
MIRT2507087	hsa-miR-1296	CLIP-seq
MIRT903902	hsa-miR-1297	CLIP-seq
MIRT2507088	hsa-miR-1299	CLIP-seq
MIRT2203886	hsa-miR-1303	CLIP-seq
MIRT1968021	hsa-miR-1322	CLIP-seq
MIRT903904	hsa-miR-137	CLIP-seq
MIRT903905	hsa-miR-154	CLIP-seq
MIRT903911	hsa-miR-2052	CLIP-seq
MIRT2507089	hsa-miR-2053	CLIP-seq
MIRT903915	hsa-miR-25	CLIP-seq
MIRT903916	hsa-miR-26a	CLIP-seq
MIRT903917	hsa-miR-26b	CLIP-seq
MIRT2507090	hsa-miR-2909	CLIP-seq
MIRT2507091	hsa-miR-31	CLIP-seq
MIRT2507092	hsa-miR-3117-5p	CLIP-seq
MIRT2203887	hsa-miR-3120-3p	CLIP-seq
MIRT903919	hsa-miR-3122	CLIP-seq
MIRT903992	hsa-miR-3123	CLIP-seq
MIRT903995	hsa-miR-3130-5p	CLIP-seq
MIRT903997	hsa-miR-3158-5p	CLIP-seq
MIRT2507093	hsa-miR-3163	CLIP-seq
MIRT903922	hsa-miR-3168	CLIP-seq
MIRT2203888	hsa-miR-3182	CLIP-seq
MIRT903924	hsa-miR-32	CLIP-seq
MIRT2507094	hsa-miR-320a	CLIP-seq
MIRT2507095	hsa-miR-320b	CLIP-seq
MIRT2507096	hsa-miR-320c	CLIP-seq
MIRT2507097	hsa-miR-320d	CLIP-seq
MIRT903998	hsa-miR-330-3p	CLIP-seq
MIRT904000	hsa-miR-3613-3p	CLIP-seq
MIRT2507098	hsa-miR-3613-5p	CLIP-seq
MIRT903929	hsa-miR-363	CLIP-seq
MIRT903930	hsa-miR-3665	CLIP-seq
MIRT903931	hsa-miR-367	CLIP-seq
MIRT903933	hsa-miR-3676	CLIP-seq
MIRT2203893	hsa-miR-371b-5p	CLIP-seq
MIRT903935	hsa-miR-3913-5p	CLIP-seq
MIRT2203894	hsa-miR-3925-5p	CLIP-seq
MIRT2507099	hsa-miR-3942-5p	CLIP-seq
MIRT903937	hsa-miR-4252	CLIP-seq
MIRT903938	hsa-miR-4255	CLIP-seq
MIRT2678455	hsa-miR-4279	CLIP-seq
MIRT903940	hsa-miR-4297	CLIP-seq
MIRT2507100	hsa-miR-4328	CLIP-seq
MIRT2507101	hsa-miR-4429	CLIP-seq
MIRT2507102	hsa-miR-4436b-3p	CLIP-seq
MIRT903943	hsa-miR-4465	CLIP-seq
MIRT904009	hsa-miR-4482	CLIP-seq
MIRT903945	hsa-miR-450b-3p	CLIP-seq
MIRT2203897	hsa-miR-450b-5p	CLIP-seq
MIRT2507103	hsa-miR-4659a-3p	CLIP-seq
MIRT2507104	hsa-miR-4659b-3p	CLIP-seq
MIRT2678456	hsa-miR-4676-5p	CLIP-seq
MIRT2507105	hsa-miR-4683	CLIP-seq
MIRT2203902	hsa-miR-4698	CLIP-seq
MIRT2507106	hsa-miR-4703-5p	CLIP-seq
MIRT904014	hsa-miR-4715-3p	CLIP-seq
MIRT2507107	hsa-miR-4761-3p	CLIP-seq
MIRT1968024	hsa-miR-4775	CLIP-seq
MIRT2507108	hsa-miR-4782-5p	CLIP-seq
MIRT1968025	hsa-miR-4789-5p	CLIP-seq
MIRT2203905	hsa-miR-489	CLIP-seq
MIRT903953	hsa-miR-498	CLIP-seq
MIRT2507110	hsa-miR-500a	CLIP-seq
MIRT2678457	hsa-miR-501-3p	CLIP-seq
MIRT2678458	hsa-miR-502-3p	CLIP-seq
MIRT2203906	hsa-miR-507	CLIP-seq
MIRT2507112	hsa-miR-516b	CLIP-seq
MIRT2203907	hsa-miR-518a-5p	CLIP-seq
MIRT2203908	hsa-miR-527	CLIP-seq
MIRT903955	hsa-miR-539	CLIP-seq
MIRT904022	hsa-miR-544	CLIP-seq
MIRT904023	hsa-miR-545	CLIP-seq
MIRT903957	hsa-miR-548a-3p	CLIP-seq
MIRT2507113	hsa-miR-548aa	CLIP-seq
MIRT2203909	hsa-miR-548ac	CLIP-seq
MIRT2203910	hsa-miR-548d-3p	CLIP-seq
MIRT903959	hsa-miR-548e	CLIP-seq
MIRT903960	hsa-miR-548f	CLIP-seq
MIRT2447457	hsa-miR-548u	CLIP-seq
MIRT2203911	hsa-miR-548z	CLIP-seq
MIRT2678459	hsa-miR-550b	CLIP-seq
MIRT2203912	hsa-miR-557	CLIP-seq
MIRT2507118	hsa-miR-569	CLIP-seq
MIRT2678460	hsa-miR-575	CLIP-seq
MIRT904027	hsa-miR-578	CLIP-seq
MIRT903962	hsa-miR-586	CLIP-seq
MIRT904028	hsa-miR-605	CLIP-seq
MIRT2507119	hsa-miR-620	CLIP-seq
MIRT904029	hsa-miR-635	CLIP-seq
MIRT2203915	hsa-miR-642b	CLIP-seq
MIRT903966	hsa-miR-657	CLIP-seq
MIRT904031	hsa-miR-659	CLIP-seq
MIRT904032	hsa-miR-758	CLIP-seq
MIRT2203916	hsa-miR-767-3p	CLIP-seq
MIRT903968	hsa-miR-769-3p	CLIP-seq
MIRT903970	hsa-miR-92a	CLIP-seq
MIRT903971	hsa-miR-92b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	ISS
GO:0000338	Process	Protein deneddylation	IBA
GO:0000338	Process	Protein deneddylation	IDA	19141280
GO:0001833	Process	Inner cell mass cell proliferation	IEA
GO:0001834	Process	Trophectodermal cell proliferation	IEA
GO:0003714	Function	Transcription corepressor activity	IEA
GO:0005515	Function	Protein binding	IPI	17438371, 20399188, 21911577, 23441852, 24421388, 25043011, 32296183, 32814053, 33961781
GO:0005634	Component	Nucleus	IDA	24421388
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	9535219, 24421388
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0006366	Process	Transcription by RNA polymerase II	TAS	7776974
GO:0006468	Process	Protein phosphorylation	IDA	9535219
GO:0007165	Process	Signal transduction	NAS	9535219
GO:0008180	Component	COP9 signalosome	IBA
GO:0008180	Component	COP9 signalosome	IDA	9535219, 18850735
GO:0008180	Component	COP9 signalosome	IEA
GO:0008180	Component	COP9 signalosome	IPI	25043011
GO:0008180	Component	COP9 signalosome	ISS
GO:0030182	Process	Neuron differentiation	IEA
GO:0032991	Component	Protein-containing complex	IEA
GO:0035914	Process	Skeletal muscle cell differentiation	IEA
GO:0045116	Process	Protein neddylation	NAS	24421388
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:2000434	Process	Regulation of protein neddylation	NAS	24421388

Other IDs

• MIM: 604508
• HGNC: 30747
• e!Ensembl: ENSG00000166200

Protein

• UniProt ID: P61201
• Protein name: COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
• Protein function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of
• PDB: 4D10, 4D18, 4WSN, 6A73, 6R6H, 6R7F, 6R7H, 6R7I, 6R7N, 8H38, 8H3A, 8H3F
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01399	PCI	309 → 413	PCI domain	Domain

• Sequence:

  MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL
  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS
  TSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQ
  TDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIREC
  GGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAK
  PYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLI
  KLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGAR
  YTALDKWTNQLNSLNQAVVSKLA

• Sequence length: 443

Pathways

Reactome:

DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ENDOMETRIOSIS	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SMALL CELL LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	8634413		★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	8634413		★☆☆☆☆ Found in Text Mining only
Amnesia	Amnesia	BEFREE	31241932		★☆☆☆☆ Found in Text Mining only
Anaplastic carcinoma	Anaplastic Carcinoma	CTD_human_DG	16316942, 9879772		★☆☆☆☆ Found in Text Mining only
Angelman Syndrome	Angelman Syndrome	BEFREE	11134237		★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia Telangiectasia	BEFREE	12198602		★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	12198602		★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar disorder	Pubtator	30503783	Associate	★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	31026346		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	15534001	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	CTD_human_DG	16316942, 9879772		★☆☆☆☆ Found in Text Mining only
Carcinoma, Spindle-Cell	Carcinoma	CTD_human_DG	16316942, 9879772		★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	17666771		★☆☆☆☆ Found in Text Mining only
Celiac Disease	Celiac disease	BEFREE	12198602		★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	11724320		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	11724320		★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	8634413		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	26942699		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	26148070, 30075461		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	26148070	Associate	★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	17666771		★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	10096780, 12198602		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	10096780, 12198602, 24432335		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	12198602, 17666771, 30213104, 9662058		★☆☆☆☆ Found in Text Mining only
Diabetes, Autoimmune	Autoimmune Diabetes	BEFREE	12198602		★☆☆☆☆ Found in Text Mining only
Endometrioma	Endometrioma	CTD_human_DG	22138541		★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	CTD_human_DG	22138541		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Global developmental delay	Developmental Delay	BEFREE	9610809		★☆☆☆☆ Found in Text Mining only
Isodicentric Chromosome 15 Syndrome	Isodicentric Chromosome 15 Syndrome	BEFREE	9610809		★☆☆☆☆ Found in Text Mining only
Lactose Intolerance	Lactose Intolerance	BEFREE	29070042, 31305326, 31773165		★☆☆☆☆ Found in Text Mining only
Latent Autoimmune Diabetes in Adults	Autoimmune Diabetes	BEFREE	12198602		★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	8634413	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	8634413		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28423737		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	31026346		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	20954701		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	11724320		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	26942699		★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	12198602		★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	BEFREE	17666771, 24432335		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	10699933, 17968325, 22777354		★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	31432133	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	20954701		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	11394883		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Undifferentiated carcinoma	Carcinoma	CTD_human_DG	16316942, 9879772		★☆☆☆☆ Found in Text Mining only