Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	93010
Gene name	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
Gene symbol	B3GNT7
Synonyms (NCBI Gene)	beta3GnT7
Chromosome	2
Chromosome location	2q37.1\|2q37.1

174

Show/Hide all (174)

miRTarBase ID	miRNA	Experiments	Reference
MIRT637768	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT637767	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT637765	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT637768	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT637767	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT660392	hsa-miR-4461	HITS-CLIP	23824327
MIRT637765	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT660391	hsa-miR-4687-5p	HITS-CLIP	23824327
MIRT660390	hsa-miR-6779-3p	HITS-CLIP	23824327
MIRT660389	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT660388	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT660387	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT660386	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT660385	hsa-miR-7975	HITS-CLIP	23824327
MIRT660384	hsa-miR-3658	HITS-CLIP	23824327
MIRT660383	hsa-miR-384	HITS-CLIP	23824327
MIRT660382	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT637768	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT637767	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT637766	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT637765	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT637768	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT637767	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT637765	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT637768	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT637767	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT660392	hsa-miR-4461	HITS-CLIP	23824327
MIRT637765	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT660391	hsa-miR-4687-5p	HITS-CLIP	23824327
MIRT660390	hsa-miR-6779-3p	HITS-CLIP	23824327
MIRT660389	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT660388	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT660387	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT660386	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT660385	hsa-miR-7975	HITS-CLIP	23824327
MIRT660384	hsa-miR-3658	HITS-CLIP	23824327
MIRT660383	hsa-miR-384	HITS-CLIP	23824327
MIRT660382	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT637768	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT637767	hsa-miR-5588-3p	HITS-CLIP	23824327
MIRT637766	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT637765	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT813414	hsa-miR-188-5p	CLIP-seq
MIRT813415	hsa-miR-214	CLIP-seq
MIRT813416	hsa-miR-3175	CLIP-seq
MIRT813417	hsa-miR-3192	CLIP-seq
MIRT813418	hsa-miR-3199	CLIP-seq
MIRT813419	hsa-miR-320e	CLIP-seq
MIRT813420	hsa-miR-326	CLIP-seq
MIRT813421	hsa-miR-330-5p	CLIP-seq
MIRT813422	hsa-miR-3619-5p	CLIP-seq
MIRT813423	hsa-miR-412	CLIP-seq
MIRT813424	hsa-miR-4291	CLIP-seq
MIRT813425	hsa-miR-4314	CLIP-seq
MIRT813426	hsa-miR-4434	CLIP-seq
MIRT813427	hsa-miR-4516	CLIP-seq
MIRT813428	hsa-miR-4533	CLIP-seq
MIRT813429	hsa-miR-4646-5p	CLIP-seq
MIRT813430	hsa-miR-4655-5p	CLIP-seq
MIRT813431	hsa-miR-4660	CLIP-seq
MIRT813432	hsa-miR-4747-5p	CLIP-seq
MIRT813433	hsa-miR-640	CLIP-seq
MIRT813434	hsa-miR-646	CLIP-seq
MIRT813435	hsa-miR-761	CLIP-seq
MIRT813436	hsa-miR-922	CLIP-seq
MIRT1940460	hsa-miR-1197	CLIP-seq
MIRT1940461	hsa-miR-125a-5p	CLIP-seq
MIRT1940462	hsa-miR-125b	CLIP-seq
MIRT1940463	hsa-miR-1915	CLIP-seq
MIRT1940464	hsa-miR-3130-3p	CLIP-seq
MIRT1940465	hsa-miR-3130-5p	CLIP-seq
MIRT1940466	hsa-miR-3151	CLIP-seq
MIRT1940467	hsa-miR-3160-3p	CLIP-seq
MIRT1940468	hsa-miR-3184	CLIP-seq
MIRT1940469	hsa-miR-3202	CLIP-seq
MIRT1940470	hsa-miR-331-3p	CLIP-seq
MIRT1940471	hsa-miR-423-5p	CLIP-seq
MIRT1940472	hsa-miR-4270	CLIP-seq
MIRT1940473	hsa-miR-4319	CLIP-seq
MIRT1940474	hsa-miR-4433	CLIP-seq
MIRT1940475	hsa-miR-4441	CLIP-seq
MIRT1940476	hsa-miR-4482	CLIP-seq
MIRT1940477	hsa-miR-4487	CLIP-seq
MIRT1940478	hsa-miR-4685-5p	CLIP-seq
MIRT1940479	hsa-miR-4755-3p	CLIP-seq
MIRT1940480	hsa-miR-4768-3p	CLIP-seq
MIRT1940481	hsa-miR-4779	CLIP-seq
MIRT1940482	hsa-miR-558	CLIP-seq
MIRT1940483	hsa-miR-564	CLIP-seq
MIRT1940484	hsa-miR-661	CLIP-seq
MIRT1940485	hsa-miR-665	CLIP-seq
MIRT2179448	hsa-miR-1	CLIP-seq
MIRT2179449	hsa-miR-1237	CLIP-seq
MIRT2179450	hsa-miR-1285	CLIP-seq
MIRT2179451	hsa-miR-1343	CLIP-seq
MIRT2179452	hsa-miR-1976	CLIP-seq
MIRT2179453	hsa-miR-206	CLIP-seq
MIRT1940464	hsa-miR-3130-3p	CLIP-seq
MIRT1940468	hsa-miR-3184	CLIP-seq
MIRT2179454	hsa-miR-3187-5p	CLIP-seq
MIRT1940469	hsa-miR-3202	CLIP-seq
MIRT2179455	hsa-miR-3667-3p	CLIP-seq
MIRT2179456	hsa-miR-3673	CLIP-seq
MIRT2179457	hsa-miR-3945	CLIP-seq
MIRT1940471	hsa-miR-423-5p	CLIP-seq
MIRT2179458	hsa-miR-4253	CLIP-seq
MIRT1940472	hsa-miR-4270	CLIP-seq
MIRT2179459	hsa-miR-4279	CLIP-seq
MIRT1940475	hsa-miR-4441	CLIP-seq
MIRT2179460	hsa-miR-4539	CLIP-seq
MIRT2179461	hsa-miR-4728-5p	CLIP-seq
MIRT813432	hsa-miR-4747-5p	CLIP-seq
MIRT1940479	hsa-miR-4755-3p	CLIP-seq
MIRT2179462	hsa-miR-4793-3p	CLIP-seq
MIRT2179463	hsa-miR-544	CLIP-seq
MIRT2179464	hsa-miR-612	CLIP-seq
MIRT2179465	hsa-miR-613	CLIP-seq
MIRT813429	hsa-miR-4646-5p	CLIP-seq
MIRT813420	hsa-miR-326	CLIP-seq
MIRT813421	hsa-miR-330-5p	CLIP-seq
MIRT2435607	hsa-miR-3918	CLIP-seq
MIRT2435608	hsa-miR-4632	CLIP-seq
MIRT2435609	hsa-miR-4667-5p	CLIP-seq
MIRT1940478	hsa-miR-4685-5p	CLIP-seq
MIRT2435610	hsa-miR-4700-5p	CLIP-seq
MIRT1940479	hsa-miR-4755-3p	CLIP-seq
MIRT2435611	hsa-miR-4757-5p	CLIP-seq
MIRT2435612	hsa-miR-637	CLIP-seq
MIRT813420	hsa-miR-326	CLIP-seq
MIRT813421	hsa-miR-330-5p	CLIP-seq
MIRT2435607	hsa-miR-3918	CLIP-seq
MIRT2435608	hsa-miR-4632	CLIP-seq
MIRT2435609	hsa-miR-4667-5p	CLIP-seq
MIRT1940478	hsa-miR-4685-5p	CLIP-seq
MIRT2435610	hsa-miR-4700-5p	CLIP-seq
MIRT1940479	hsa-miR-4755-3p	CLIP-seq
MIRT2435611	hsa-miR-4757-5p	CLIP-seq
MIRT2435612	hsa-miR-637	CLIP-seq
MIRT2444562	hsa-miR-1470	CLIP-seq
MIRT2444563	hsa-miR-3620	CLIP-seq
MIRT2444564	hsa-miR-3689d	CLIP-seq
MIRT2444565	hsa-miR-4254	CLIP-seq
MIRT2444566	hsa-miR-4286	CLIP-seq
MIRT2444567	hsa-miR-4308	CLIP-seq
MIRT2444568	hsa-miR-4469	CLIP-seq
MIRT2444569	hsa-miR-4667-3p	CLIP-seq
MIRT2179451	hsa-miR-1343	CLIP-seq
MIRT2444562	hsa-miR-1470	CLIP-seq
MIRT2179452	hsa-miR-1976	CLIP-seq
MIRT2444563	hsa-miR-3620	CLIP-seq
MIRT2444564	hsa-miR-3689d	CLIP-seq
MIRT2444565	hsa-miR-4254	CLIP-seq
MIRT2179459	hsa-miR-4279	CLIP-seq
MIRT2444566	hsa-miR-4286	CLIP-seq
MIRT2444567	hsa-miR-4308	CLIP-seq
MIRT2444568	hsa-miR-4469	CLIP-seq
MIRT2482927	hsa-miR-4522	CLIP-seq
MIRT2444569	hsa-miR-4667-3p	CLIP-seq
MIRT2435612	hsa-miR-637	CLIP-seq
MIRT2482928	hsa-miR-942	CLIP-seq
MIRT2179451	hsa-miR-1343	CLIP-seq
MIRT2444562	hsa-miR-1470	CLIP-seq
MIRT2179452	hsa-miR-1976	CLIP-seq
MIRT2444563	hsa-miR-3620	CLIP-seq
MIRT2444564	hsa-miR-3689d	CLIP-seq
MIRT2444565	hsa-miR-4254	CLIP-seq
MIRT2179459	hsa-miR-4279	CLIP-seq
MIRT2444566	hsa-miR-4286	CLIP-seq
MIRT2444567	hsa-miR-4308	CLIP-seq
MIRT2444568	hsa-miR-4469	CLIP-seq
MIRT2482927	hsa-miR-4522	CLIP-seq
MIRT2444569	hsa-miR-4667-3p	CLIP-seq
MIRT2435612	hsa-miR-637	CLIP-seq
MIRT2482928	hsa-miR-942	CLIP-seq

Show/Hide all (20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006493	Process	Protein O-linked glycosylation	IBA
GO:0008194	Function	UDP-glycosyltransferase activity	IBA
GO:0008375	Function	Acetylglucosaminyltransferase activity	IDA	17690104
GO:0008499	Function	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	TAS
GO:0008532	Function	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	TAS
GO:0016020	Component	Membrane	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0016758	Function	Hexosyltransferase activity	IEA
GO:0018146	Process	Keratan sulfate proteoglycan biosynthetic process	IDA	17690104
GO:0018146	Process	Keratan sulfate proteoglycan biosynthetic process	IEA
GO:0018146	Process	Keratan sulfate proteoglycan biosynthetic process	TAS
GO:0030311	Process	Poly-N-acetyllactosamine biosynthetic process	IBA

MIM	HGNC	e!Ensembl
615313	18811	ENSG00000156966

Q8NFL0

Protein name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (BGnT-7) (Beta-1,3-Gn-T7) (Beta-1,3-N-acetylglucosaminyltransferase 7) (Beta3Gn-T7) (EC 2.4.1.-)

Protein function

N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. C

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01762	Galactosyl_T	148 → 345	Galactosyltransferase	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in corneal epithelial cells. {ECO:0000269|PubMed:17690104}.

Sequence

MSLWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNN
FWKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYF
PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA
SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD
DDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGG
GGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRM
NKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL

Sequence length

401

Interactions

View interactions

	KEGG		Reactome
	Glycosaminoglycan biosynthesis - keratan sulfate		Keratan sulfate biosynthesis O-linked glycosylation of mucins

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATOPIC ECZEMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EATING DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of colon	Adenocarcinoma Of Colon	BEFREE	24418929		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	27485113	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	37740763	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	24418929		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34302946	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	24418929		★★★★★ ★☆☆☆☆ Found in Text Mining only

B3GNT7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7)