Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	92822
Gene name	Zinc finger protein 276
Gene symbol	ZNF276
Synonyms (NCBI Gene)	CENP-ZCENPZZADTZFP276ZNF477
Chromosome	16
Chromosome location	16q24.3

204

Show/Hide all (204)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049143	hsa-miR-92a-3p	CLASH	23622248
MIRT045493	hsa-miR-149-5p	CLASH	23622248
MIRT1520525	hsa-miR-1207-5p	CLIP-seq
MIRT1520526	hsa-miR-1225-3p	CLIP-seq
MIRT1520527	hsa-miR-1228	CLIP-seq
MIRT1520528	hsa-miR-1281	CLIP-seq
MIRT1520529	hsa-miR-1288	CLIP-seq
MIRT1520530	hsa-miR-1470	CLIP-seq
MIRT1520531	hsa-miR-150	CLIP-seq
MIRT1520532	hsa-miR-1909	CLIP-seq
MIRT1520533	hsa-miR-1976	CLIP-seq
MIRT1520534	hsa-miR-224	CLIP-seq
MIRT1520535	hsa-miR-2681	CLIP-seq
MIRT1520536	hsa-miR-2861	CLIP-seq
MIRT1520537	hsa-miR-29a	CLIP-seq
MIRT1520538	hsa-miR-29b	CLIP-seq
MIRT1520539	hsa-miR-29c	CLIP-seq
MIRT1520540	hsa-miR-3065-3p	CLIP-seq
MIRT1520541	hsa-miR-3130-3p	CLIP-seq
MIRT1520542	hsa-miR-3141	CLIP-seq
MIRT1520543	hsa-miR-3144-5p	CLIP-seq
MIRT1520544	hsa-miR-3156-3p	CLIP-seq
MIRT1520545	hsa-miR-3183	CLIP-seq
MIRT1520546	hsa-miR-3191	CLIP-seq
MIRT1520547	hsa-miR-3199	CLIP-seq
MIRT1520548	hsa-miR-331-3p	CLIP-seq
MIRT1520549	hsa-miR-338-3p	CLIP-seq
MIRT1520550	hsa-miR-3687	CLIP-seq
MIRT1520551	hsa-miR-3909	CLIP-seq
MIRT1520552	hsa-miR-4265	CLIP-seq
MIRT1520553	hsa-miR-4296	CLIP-seq
MIRT1520554	hsa-miR-4301	CLIP-seq
MIRT1520555	hsa-miR-4318	CLIP-seq
MIRT1520556	hsa-miR-4322	CLIP-seq
MIRT1520557	hsa-miR-4417	CLIP-seq
MIRT1520558	hsa-miR-4438	CLIP-seq
MIRT1520559	hsa-miR-4442	CLIP-seq
MIRT1520560	hsa-miR-4514	CLIP-seq
MIRT1520561	hsa-miR-4530	CLIP-seq
MIRT1520562	hsa-miR-4537	CLIP-seq
MIRT1520563	hsa-miR-4640-5p	CLIP-seq
MIRT1520564	hsa-miR-4645-5p	CLIP-seq
MIRT1520565	hsa-miR-4652-5p	CLIP-seq
MIRT1520566	hsa-miR-4667-3p	CLIP-seq
MIRT1520567	hsa-miR-4673	CLIP-seq
MIRT1520568	hsa-miR-4688	CLIP-seq
MIRT1520569	hsa-miR-4692	CLIP-seq
MIRT1520570	hsa-miR-4707-3p	CLIP-seq
MIRT1520571	hsa-miR-4713-5p	CLIP-seq
MIRT1520572	hsa-miR-4723-3p	CLIP-seq
MIRT1520573	hsa-miR-4726-5p	CLIP-seq
MIRT1520574	hsa-miR-4727-5p	CLIP-seq
MIRT1520575	hsa-miR-4749-3p	CLIP-seq
MIRT1520576	hsa-miR-4755-3p	CLIP-seq
MIRT1520577	hsa-miR-4761-5p	CLIP-seq
MIRT1520578	hsa-miR-4763-3p	CLIP-seq
MIRT1520579	hsa-miR-4769-3p	CLIP-seq
MIRT1520580	hsa-miR-4793-3p	CLIP-seq
MIRT1520581	hsa-miR-5095	CLIP-seq
MIRT1520582	hsa-miR-532-3p	CLIP-seq
MIRT1520583	hsa-miR-544	CLIP-seq
MIRT1520584	hsa-miR-627	CLIP-seq
MIRT1520585	hsa-miR-634	CLIP-seq
MIRT1520586	hsa-miR-766	CLIP-seq
MIRT1520587	hsa-miR-767-5p	CLIP-seq
MIRT1520588	hsa-miR-924	CLIP-seq
MIRT1520589	hsa-miR-940	CLIP-seq
MIRT1520590	hsa-miR-941	CLIP-seq
MIRT1520591	hsa-miR-105	CLIP-seq
MIRT1520592	hsa-miR-122	CLIP-seq
MIRT1520593	hsa-miR-1224-5p	CLIP-seq
MIRT1520594	hsa-miR-1251	CLIP-seq
MIRT1520595	hsa-miR-1273f	CLIP-seq
MIRT1520596	hsa-miR-129-5p	CLIP-seq
MIRT1520597	hsa-miR-1304	CLIP-seq
MIRT1520598	hsa-miR-143	CLIP-seq
MIRT1520599	hsa-miR-1827	CLIP-seq
MIRT1520600	hsa-miR-2467-5p	CLIP-seq
MIRT1520601	hsa-miR-3135b	CLIP-seq
MIRT1520602	hsa-miR-3188	CLIP-seq
MIRT1520603	hsa-miR-3650	CLIP-seq
MIRT1520604	hsa-miR-3652	CLIP-seq
MIRT1520605	hsa-miR-3664-5p	CLIP-seq
MIRT1520606	hsa-miR-3915	CLIP-seq
MIRT1520607	hsa-miR-3929	CLIP-seq
MIRT1520608	hsa-miR-3975	CLIP-seq
MIRT1520609	hsa-miR-4316	CLIP-seq
MIRT1520610	hsa-miR-4419b	CLIP-seq
MIRT1520611	hsa-miR-4430	CLIP-seq
MIRT1520612	hsa-miR-4478	CLIP-seq
MIRT1520613	hsa-miR-4639-3p	CLIP-seq
MIRT1520614	hsa-miR-4649-3p	CLIP-seq
MIRT1520615	hsa-miR-4663	CLIP-seq
MIRT1520616	hsa-miR-4689	CLIP-seq
MIRT1520617	hsa-miR-4691-3p	CLIP-seq
MIRT1520618	hsa-miR-4695-3p	CLIP-seq
MIRT1520619	hsa-miR-4708-5p	CLIP-seq
MIRT1520620	hsa-miR-4710	CLIP-seq
MIRT1520621	hsa-miR-4719	CLIP-seq
MIRT1520622	hsa-miR-4768-5p	CLIP-seq
MIRT1520623	hsa-miR-4770	CLIP-seq
MIRT1520624	hsa-miR-485-5p	CLIP-seq
MIRT1520625	hsa-miR-629	CLIP-seq
MIRT1520626	hsa-miR-642b	CLIP-seq
MIRT1555793	hsa-miR-3180-5p	CLIP-seq
MIRT1555794	hsa-miR-3664-3p	CLIP-seq
MIRT1555795	hsa-miR-4661-5p	CLIP-seq
MIRT1555796	hsa-miR-520a-5p	CLIP-seq
MIRT1555797	hsa-miR-525-5p	CLIP-seq
MIRT2157129	hsa-miR-1202	CLIP-seq
MIRT1520593	hsa-miR-1224-5p	CLIP-seq
MIRT2157130	hsa-miR-1226	CLIP-seq
MIRT1520527	hsa-miR-1228	CLIP-seq
MIRT2157131	hsa-miR-1279	CLIP-seq
MIRT1520597	hsa-miR-1304	CLIP-seq
MIRT2157132	hsa-miR-193a-3p	CLIP-seq
MIRT2157133	hsa-miR-193b	CLIP-seq
MIRT2157134	hsa-miR-197	CLIP-seq
MIRT2157135	hsa-miR-198	CLIP-seq
MIRT2157136	hsa-miR-297	CLIP-seq
MIRT2157137	hsa-miR-3125	CLIP-seq
MIRT2157138	hsa-miR-3152-5p	CLIP-seq
MIRT2157139	hsa-miR-3176	CLIP-seq
MIRT2157140	hsa-miR-3182	CLIP-seq
MIRT2157141	hsa-miR-3622a-3p	CLIP-seq
MIRT2157142	hsa-miR-3622b-3p	CLIP-seq
MIRT2157143	hsa-miR-365	CLIP-seq
MIRT2157144	hsa-miR-3907	CLIP-seq
MIRT1520606	hsa-miR-3915	CLIP-seq
MIRT2157145	hsa-miR-3916	CLIP-seq
MIRT2157146	hsa-miR-3922-3p	CLIP-seq
MIRT2157147	hsa-miR-3942-5p	CLIP-seq
MIRT2157148	hsa-miR-3972	CLIP-seq
MIRT2157149	hsa-miR-411	CLIP-seq
MIRT2157150	hsa-miR-4290	CLIP-seq
MIRT2157151	hsa-miR-4422	CLIP-seq
MIRT1520558	hsa-miR-4438	CLIP-seq
MIRT2157152	hsa-miR-4503	CLIP-seq
MIRT2157153	hsa-miR-4677-3p	CLIP-seq
MIRT1520616	hsa-miR-4689	CLIP-seq
MIRT1520617	hsa-miR-4691-3p	CLIP-seq
MIRT2157154	hsa-miR-4703-5p	CLIP-seq
MIRT2157155	hsa-miR-4751	CLIP-seq
MIRT1520576	hsa-miR-4755-3p	CLIP-seq
MIRT2157156	hsa-miR-4757-5p	CLIP-seq
MIRT2157157	hsa-miR-4758-3p	CLIP-seq
MIRT2157158	hsa-miR-4774-3p	CLIP-seq
MIRT2157159	hsa-miR-490-3p	CLIP-seq
MIRT1520581	hsa-miR-5095	CLIP-seq
MIRT2157160	hsa-miR-5096	CLIP-seq
MIRT1555796	hsa-miR-520a-5p	CLIP-seq
MIRT1555797	hsa-miR-525-5p	CLIP-seq
MIRT2157161	hsa-miR-567	CLIP-seq
MIRT2157162	hsa-miR-583	CLIP-seq
MIRT1520584	hsa-miR-627	CLIP-seq
MIRT2157163	hsa-miR-649	CLIP-seq
MIRT2157164	hsa-miR-654-3p	CLIP-seq
MIRT1520588	hsa-miR-924	CLIP-seq
MIRT1520590	hsa-miR-941	CLIP-seq
MIRT1520527	hsa-miR-1228	CLIP-seq
MIRT2376830	hsa-miR-1234	CLIP-seq
MIRT2376831	hsa-miR-4252	CLIP-seq
MIRT1520558	hsa-miR-4438	CLIP-seq
MIRT1520581	hsa-miR-5095	CLIP-seq
MIRT1520584	hsa-miR-627	CLIP-seq
MIRT1520588	hsa-miR-924	CLIP-seq
MIRT1520590	hsa-miR-941	CLIP-seq
MIRT2157129	hsa-miR-1202	CLIP-seq
MIRT1520527	hsa-miR-1228	CLIP-seq
MIRT2157131	hsa-miR-1279	CLIP-seq
MIRT2157134	hsa-miR-197	CLIP-seq
MIRT2668922	hsa-miR-3653	CLIP-seq
MIRT2668923	hsa-miR-3658	CLIP-seq
MIRT2157148	hsa-miR-3972	CLIP-seq
MIRT2157149	hsa-miR-411	CLIP-seq
MIRT2668924	hsa-miR-4511	CLIP-seq
MIRT1520576	hsa-miR-4755-3p	CLIP-seq
MIRT2157160	hsa-miR-5096	CLIP-seq
MIRT2668925	hsa-miR-518a-5p	CLIP-seq
MIRT2668926	hsa-miR-522	CLIP-seq
MIRT2668927	hsa-miR-527	CLIP-seq
MIRT2668928	hsa-miR-548b-3p	CLIP-seq
MIRT1520584	hsa-miR-627	CLIP-seq
MIRT1520588	hsa-miR-924	CLIP-seq
MIRT1520590	hsa-miR-941	CLIP-seq
MIRT2157129	hsa-miR-1202	CLIP-seq
MIRT1520527	hsa-miR-1228	CLIP-seq
MIRT2157131	hsa-miR-1279	CLIP-seq
MIRT2157134	hsa-miR-197	CLIP-seq
MIRT2157136	hsa-miR-297	CLIP-seq
MIRT2695885	hsa-miR-3686	CLIP-seq
MIRT2157148	hsa-miR-3972	CLIP-seq
MIRT2157149	hsa-miR-411	CLIP-seq
MIRT2157153	hsa-miR-4677-3p	CLIP-seq
MIRT2695886	hsa-miR-4742-3p	CLIP-seq
MIRT1520576	hsa-miR-4755-3p	CLIP-seq
MIRT2157159	hsa-miR-490-3p	CLIP-seq
MIRT2157160	hsa-miR-5096	CLIP-seq
MIRT2157161	hsa-miR-567	CLIP-seq
MIRT1520584	hsa-miR-627	CLIP-seq
MIRT2157163	hsa-miR-649	CLIP-seq
MIRT2157164	hsa-miR-654-3p	CLIP-seq
MIRT1520588	hsa-miR-924	CLIP-seq
MIRT1520590	hsa-miR-941	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000775	Component	Chromosome, centromeric region	IEA
GO:0000776	Component	Kinetochore	IBA
GO:0000776	Component	Kinetochore	IDA	20813266
GO:0000776	Component	Kinetochore	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 16713569, 25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IBA
GO:0005694	Component	Chromosome	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0043035	Function	Chromatin insulator sequence binding	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
608460	23330	ENSG00000158805

Q8N554

Protein name

Zinc finger protein 276 (Zfp-276) (Zinc finger protein 477)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07776	zf-AD	78 → 160	Zinc-finger associated domain (zf-AD)	Domain
PF00096	zf-C2H2	496 → 518	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	554 → 577	Zinc finger, C2H2 type	Domain

Sequence

MKRDRLGRFLSPGSSRQCGASDGGGGVSRTRGRPSLSGGPRVDGATARRAWGPVGSCGDA
GEDGADEAGAGRALAMGHCRLCHGKFSSRSLRSISERAPGASMERPSAEERVLVRDFQRL
LGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQRVNASPAGRRKPCAKVGAQPPTGAE
EGACLVDLITSSPQCLHGLVGWVHGHAASCGALPHLQRTLSSEYCGVIQVVWGCDQGHDY
TMDTSSSCKAFLLDSALAVKWPWDKETAPRLPQHRGWNPGDAPQTSQGRGTGTPVGAETK
TLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGQLGEKQLPSSTSDDRVKDEFSDLS
EGDVLSEDENDKKQNAQSSDESFEPYPERKVSGKKSESKEAKKSEEPRIRKKPGPKPGWK
KKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDR
YLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLK
YHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSP
SVTTEGQAVKPEPT

Sequence length

614

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (30)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATOPIC ECZEMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BASAL CELL CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BILIARY TRACT CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CERVICAL CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESTROGEN-RECEPTOR NEGATIVE BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FANCONI ANEMIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FANCONI ANEMIA, COMPLEMENTATION GROUP A	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Uncertain significance	ClinVar GWAS catalog	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
HEPATOCELLULAR CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KERATINOCYTE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-HODGKINS LYMPHOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-MELANOMA SKIN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN ENDOMETRIOID CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN SEROUS CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SKIN DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL LUNG CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Carcinoma	Breast Carcinoma	BEFREE	14605947		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Fanconi Anemia	Fanconi Anemia	CLINVAR_DG	10094191, 15643609, 17924555, 19367192, 21273304, 24584348, 28102861, 28717661, 29098742, 9371798		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Fanconi Anemia	Fanconi Anemia	BEFREE	10936049		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	CLINVAR_DG	10521298, 12444097, 15059067, 15523645, 15643609, 17924555, 19278965, 19367192, 21273304, 23613520, 23934222, 23973728, 24037726, 24584348, 26366677, 27041517, 28717661, 29098742, 9371798 View all (4 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	BEFREE	10936049		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	14605947		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	14605947		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	25243787	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma Cutaneous Malignant	Melanoma	Pubtator	25243787	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	14605947		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	37143720	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF276 (zinc finger protein 276)