TMEM169 (transmembrane protein 169)

Gene

• Entrez ID: 92691
• Gene name: Transmembrane protein 169
• Gene symbol: TMEM169
• Synonyms (NCBI Gene): -
• Chromosome: 2
• Chromosome location: 2q35

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024545	hsa-miR-215-5p	Microarray	19074876
MIRT026431	hsa-miR-192-5p	Microarray	19074876
MIRT648547	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT648545	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT648546	hsa-miR-2682-3p	HITS-CLIP	23824327
MIRT648544	hsa-miR-6781-3p	HITS-CLIP	23824327
MIRT648543	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT648542	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT648541	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT648540	hsa-miR-1178-3p	HITS-CLIP	23824327
MIRT648539	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT648538	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT648547	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT648545	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT648546	hsa-miR-2682-3p	HITS-CLIP	23824327
MIRT648544	hsa-miR-6781-3p	HITS-CLIP	23824327
MIRT648543	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT648542	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT648541	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT648540	hsa-miR-1178-3p	HITS-CLIP	23824327
MIRT648539	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT648538	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT1432508	hsa-miR-1197	CLIP-seq
MIRT1432509	hsa-miR-1227	CLIP-seq
MIRT1432510	hsa-miR-203	CLIP-seq
MIRT1432511	hsa-miR-3145-3p	CLIP-seq
MIRT1432512	hsa-miR-3154	CLIP-seq
MIRT1432513	hsa-miR-3646	CLIP-seq
MIRT1432514	hsa-miR-371-3p	CLIP-seq
MIRT1432515	hsa-miR-4252	CLIP-seq
MIRT1432516	hsa-miR-4793-3p	CLIP-seq
MIRT1432517	hsa-miR-508-5p	CLIP-seq
MIRT1432518	hsa-miR-519e	CLIP-seq
MIRT1432519	hsa-miR-766	CLIP-seq
MIRT1432520	hsa-miR-1206	CLIP-seq
MIRT1432521	hsa-miR-1207-5p	CLIP-seq
MIRT1432522	hsa-miR-1224-3p	CLIP-seq
MIRT1432523	hsa-miR-1260	CLIP-seq
MIRT1432524	hsa-miR-1260b	CLIP-seq
MIRT1432525	hsa-miR-1280	CLIP-seq
MIRT1432526	hsa-miR-1285	CLIP-seq
MIRT1432527	hsa-miR-1294	CLIP-seq
MIRT1432528	hsa-miR-1296	CLIP-seq
MIRT1432529	hsa-miR-2278	CLIP-seq
MIRT1432530	hsa-miR-2909	CLIP-seq
MIRT1432531	hsa-miR-29a	CLIP-seq
MIRT1432532	hsa-miR-29b	CLIP-seq
MIRT1432533	hsa-miR-29c	CLIP-seq
MIRT1432534	hsa-miR-3122	CLIP-seq
MIRT1432535	hsa-miR-338-3p	CLIP-seq
MIRT1432536	hsa-miR-3613-3p	CLIP-seq
MIRT1432537	hsa-miR-3663-3p	CLIP-seq
MIRT1432538	hsa-miR-3675-3p	CLIP-seq
MIRT1432539	hsa-miR-3913-5p	CLIP-seq
MIRT1432540	hsa-miR-3973	CLIP-seq
MIRT1432541	hsa-miR-4310	CLIP-seq
MIRT1432542	hsa-miR-4436a	CLIP-seq
MIRT1432543	hsa-miR-4436b-3p	CLIP-seq
MIRT1432544	hsa-miR-4717-3p	CLIP-seq
MIRT1432545	hsa-miR-4729	CLIP-seq
MIRT1432546	hsa-miR-4733-3p	CLIP-seq
MIRT1432547	hsa-miR-4761-3p	CLIP-seq
MIRT1432548	hsa-miR-4763-3p	CLIP-seq
MIRT1432549	hsa-miR-4774-3p	CLIP-seq
MIRT1432550	hsa-miR-501-3p	CLIP-seq
MIRT1432551	hsa-miR-502-3p	CLIP-seq
MIRT1432552	hsa-miR-511	CLIP-seq
MIRT1432553	hsa-miR-518a-5p	CLIP-seq
MIRT1432554	hsa-miR-527	CLIP-seq
MIRT1432555	hsa-miR-548k	CLIP-seq
MIRT1432556	hsa-miR-579	CLIP-seq
MIRT1432557	hsa-miR-767-5p	CLIP-seq
MIRT1432526	hsa-miR-1285	CLIP-seq
MIRT2129646	hsa-miR-149	CLIP-seq
MIRT2129647	hsa-miR-1827	CLIP-seq
MIRT1432530	hsa-miR-2909	CLIP-seq
MIRT2129648	hsa-miR-3064-5p	CLIP-seq
MIRT2129649	hsa-miR-3065-3p	CLIP-seq
MIRT1432534	hsa-miR-3122	CLIP-seq
MIRT2129650	hsa-miR-3126-3p	CLIP-seq
MIRT2129651	hsa-miR-3529	CLIP-seq
MIRT1432513	hsa-miR-3646	CLIP-seq
MIRT2129652	hsa-miR-3672	CLIP-seq
MIRT2129653	hsa-miR-3689a-3p	CLIP-seq
MIRT2129654	hsa-miR-3689c	CLIP-seq
MIRT2129655	hsa-miR-379	CLIP-seq
MIRT1432539	hsa-miR-3913-5p	CLIP-seq
MIRT2129656	hsa-miR-3937	CLIP-seq
MIRT2129657	hsa-miR-4433	CLIP-seq
MIRT1432544	hsa-miR-4717-3p	CLIP-seq
MIRT2129658	hsa-miR-4728-5p	CLIP-seq
MIRT1432516	hsa-miR-4793-3p	CLIP-seq
MIRT2129659	hsa-miR-4794	CLIP-seq
MIRT2129660	hsa-miR-940	CLIP-seq
MIRT1432526	hsa-miR-1285	CLIP-seq
MIRT2351148	hsa-miR-141	CLIP-seq
MIRT2129647	hsa-miR-1827	CLIP-seq
MIRT2351149	hsa-miR-200a	CLIP-seq
MIRT2351150	hsa-miR-2964a-3p	CLIP-seq
MIRT1432534	hsa-miR-3122	CLIP-seq
MIRT2129653	hsa-miR-3689a-3p	CLIP-seq
MIRT2129654	hsa-miR-3689c	CLIP-seq
MIRT1432539	hsa-miR-3913-5p	CLIP-seq
MIRT2129656	hsa-miR-3937	CLIP-seq
MIRT1432515	hsa-miR-4252	CLIP-seq
MIRT2351151	hsa-miR-4267	CLIP-seq
MIRT2351152	hsa-miR-4269	CLIP-seq
MIRT2351153	hsa-miR-4277	CLIP-seq
MIRT2129657	hsa-miR-4433	CLIP-seq
MIRT2351154	hsa-miR-4536	CLIP-seq
MIRT2351155	hsa-miR-4645-5p	CLIP-seq
MIRT2351156	hsa-miR-4673	CLIP-seq
MIRT1432544	hsa-miR-4717-3p	CLIP-seq
MIRT2129658	hsa-miR-4728-5p	CLIP-seq
MIRT1432516	hsa-miR-4793-3p	CLIP-seq
MIRT2351157	hsa-miR-4797-5p	CLIP-seq
MIRT1432517	hsa-miR-508-5p	CLIP-seq
MIRT2351158	hsa-miR-516a-3p	CLIP-seq
MIRT1432519	hsa-miR-766	CLIP-seq
MIRT2351159	hsa-miR-802	CLIP-seq
MIRT2129660	hsa-miR-940	CLIP-seq
MIRT2644841	hsa-miR-124	CLIP-seq
MIRT2351150	hsa-miR-2964a-3p	CLIP-seq
MIRT1432534	hsa-miR-3122	CLIP-seq
MIRT1432535	hsa-miR-338-3p	CLIP-seq
MIRT1432538	hsa-miR-3675-3p	CLIP-seq
MIRT2129653	hsa-miR-3689a-3p	CLIP-seq
MIRT2129654	hsa-miR-3689c	CLIP-seq
MIRT1432539	hsa-miR-3913-5p	CLIP-seq
MIRT1432541	hsa-miR-4310	CLIP-seq
MIRT2644842	hsa-miR-4684-5p	CLIP-seq
MIRT1432544	hsa-miR-4717-3p	CLIP-seq
MIRT2129658	hsa-miR-4728-5p	CLIP-seq
MIRT1432549	hsa-miR-4774-3p	CLIP-seq
MIRT2644843	hsa-miR-506	CLIP-seq
MIRT2644841	hsa-miR-124	CLIP-seq
MIRT2351150	hsa-miR-2964a-3p	CLIP-seq
MIRT1432538	hsa-miR-3675-3p	CLIP-seq
MIRT2644842	hsa-miR-4684-5p	CLIP-seq
MIRT2644843	hsa-miR-506	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96HH4
• Protein name: Transmembrane protein 169
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15052	TMEM169	147 → 277	TMEM169 protein family	Family

• Sequence:

  MEEPTAVEGQVQLPSPHQGSLRKAVAAALALDGESTMGHRKKKRKESRPESIIIYRSDNE
  KTDEEPGESEGGDQPKEEEGDDFLDYPVDDDMWNLPLDSRYVTLTGTITRGKKKGQMVDI
  HVTLTEKELQELTKPKESSRETTPEGRMACQMGADRGPHVVLWTLICLPVVFILSFVVSF
  YYGTITWYNIFLVYNEERTFWHKISYCPCLVLFYPVLIMAMASSLGLYAAVVQLSWSWEA
  WWQAARDMEKGFCGWLCSKLGLEDCSPYSIVELLESDNISSTLSNKDPIQEVETSTV

• Sequence length: 297

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
HODGKINS LYMPHOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations