Gene Gene information from NCBI Gene database.
Entrez ID 92689
Gene name Family with sequence similarity 114 member A1
Gene symbol FAM114A1
Synonyms (NCBI Gene)
Noxp20
Chromosome 4
Chromosome location 4p14
Summary The protein encoded by this gene belongs to the FAM114 family and may play a role in neuronal cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
miRNA miRNA information provided by mirtarbase database.
826
miRTarBase ID miRNA Experiments Reference
MIRT017402 hsa-miR-335-5p Microarray 18185580
MIRT717821 hsa-miR-519a-3p HITS-CLIP 19536157
MIRT717820 hsa-miR-519b-3p HITS-CLIP 19536157
MIRT717819 hsa-miR-519c-3p HITS-CLIP 19536157
MIRT717818 hsa-miR-302a-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
GO ID Ontology Definition Evidence Reference
GO:0003179 Process Heart valve morphogenesis IEA
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183, 33961781
GO:0005654 Component Nucleoplasm IDA
GO:0005737 Component Cytoplasm IEA
GO:0005794 Component Golgi apparatus IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IWE2
Protein name Protein NOXP20 (Nervous system overexpressed protein 20) (Protein FAM114A1)
Protein function May play a role in neuronal cell development.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05334 DUF719 125 299 Protein of unknown function (DUF719) Family
Sequence
MSDDAGDTLATGDKAEVTEMPNSDSLPEDAEVHCDSAAVSHEPTPADPRGEGHENAAVQG
AGAAAIGPPVQPQDANALEPPLNGDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYLAVDS
PPSGGGWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENG
VPEITDAATDQGPAESPPTSPSSASRGMLSAITNVVQNTGKSVLTGGLDALEFIGKKTMN
VLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGL
S
HLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEE
KGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEK
EEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ
DQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSVLLEGCNSTTYIQD
AFQLLLPVLQVSHIQTSCLKAQP
Sequence length 563
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
NON-SMALL CELL LUNG CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
RESTLESS LEGS SYNDROME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Coronary Syndrome Coronary Syndrome GWASCAT_DG 28753643
★☆☆☆☆
Found in Text Mining only
Breast Neoplasms Breast neoplasm Pubtator 35441810 Associate
★☆☆☆☆
Found in Text Mining only
Coronary heart disease Coronary Heart Disease GWASCAT_DG 28753643
★☆☆☆☆
Found in Text Mining only
Prostatic Neoplasms Prostatic neoplasm Pubtator 32800727 Associate
★☆☆☆☆
Found in Text Mining only
Spondylitis Ankylosing Ankylosing spondylitis Pubtator 34837888 Associate
★☆☆☆☆
Found in Text Mining only
Vitiligo Vitiligo Pubtator 34837888 Associate
★☆☆☆☆
Found in Text Mining only