CYTH2 (cytohesin 2)

Gene

• Entrez ID: 9266
• Gene name: Cytohesin 2
• Gene symbol: CYTH2
• Synonyms (NCBI Gene): ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like, cytohesin-2
• Chromosome: 19
• Chromosome location: 19q13.33
• Summary: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The c

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT030082	hsa-miR-26b-5p	Microarray	19088304
MIRT045806	hsa-miR-191-5p	CLASH	23622248
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT715570	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT715570	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT715570	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT715570	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT715570	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT712531	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT712530	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT712529	hsa-miR-3937	HITS-CLIP	19536157
MIRT712528	hsa-miR-5090	HITS-CLIP	19536157
MIRT712527	hsa-miR-6775-5p	HITS-CLIP	19536157
MIRT712526	hsa-miR-4660	HITS-CLIP	19536157
MIRT712525	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT712524	hsa-miR-663a	HITS-CLIP	19536157
MIRT712523	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT712522	hsa-miR-486-3p	HITS-CLIP	19536157
MIRT922136	hsa-miR-1207-5p	CLIP-seq
MIRT922137	hsa-miR-1224-5p	CLIP-seq
MIRT922138	hsa-miR-1228	CLIP-seq
MIRT922139	hsa-miR-1269	CLIP-seq
MIRT922140	hsa-miR-1269b	CLIP-seq
MIRT922141	hsa-miR-1275	CLIP-seq
MIRT922142	hsa-miR-1288	CLIP-seq
MIRT922143	hsa-miR-142-5p	CLIP-seq
MIRT922144	hsa-miR-149	CLIP-seq
MIRT922145	hsa-miR-1827	CLIP-seq
MIRT922146	hsa-miR-1909	CLIP-seq
MIRT922147	hsa-miR-1913	CLIP-seq
MIRT922148	hsa-miR-193a-3p	CLIP-seq
MIRT922149	hsa-miR-193a-5p	CLIP-seq
MIRT922150	hsa-miR-193b	CLIP-seq
MIRT922151	hsa-miR-2053	CLIP-seq
MIRT922152	hsa-miR-24	CLIP-seq
MIRT922153	hsa-miR-2467-5p	CLIP-seq
MIRT922154	hsa-miR-3122	CLIP-seq
MIRT922155	hsa-miR-3126-5p	CLIP-seq
MIRT922156	hsa-miR-3128	CLIP-seq
MIRT922157	hsa-miR-3133	CLIP-seq
MIRT922158	hsa-miR-3134	CLIP-seq
MIRT922159	hsa-miR-3136-3p	CLIP-seq
MIRT922160	hsa-miR-3151	CLIP-seq
MIRT922161	hsa-miR-3175	CLIP-seq
MIRT922162	hsa-miR-3180	CLIP-seq
MIRT922163	hsa-miR-3180-3p	CLIP-seq
MIRT922164	hsa-miR-3188	CLIP-seq
MIRT922165	hsa-miR-3192	CLIP-seq
MIRT922166	hsa-miR-3196	CLIP-seq
MIRT922167	hsa-miR-324-3p	CLIP-seq
MIRT922168	hsa-miR-324-5p	CLIP-seq
MIRT922169	hsa-miR-330-3p	CLIP-seq
MIRT922170	hsa-miR-340	CLIP-seq
MIRT922171	hsa-miR-342-3p	CLIP-seq
MIRT922172	hsa-miR-3648	CLIP-seq
MIRT922173	hsa-miR-3665	CLIP-seq
MIRT922174	hsa-miR-3680	CLIP-seq
MIRT922175	hsa-miR-3913-5p	CLIP-seq
MIRT922176	hsa-miR-3929	CLIP-seq
MIRT922177	hsa-miR-3960	CLIP-seq
MIRT922178	hsa-miR-3974	CLIP-seq
MIRT922179	hsa-miR-3975	CLIP-seq
MIRT922180	hsa-miR-4265	CLIP-seq
MIRT922181	hsa-miR-4284	CLIP-seq
MIRT922182	hsa-miR-4290	CLIP-seq
MIRT922183	hsa-miR-4296	CLIP-seq
MIRT922184	hsa-miR-4318	CLIP-seq
MIRT922185	hsa-miR-4322	CLIP-seq
MIRT922186	hsa-miR-4327	CLIP-seq
MIRT922187	hsa-miR-4329	CLIP-seq
MIRT922188	hsa-miR-4417	CLIP-seq
MIRT922189	hsa-miR-4419b	CLIP-seq
MIRT922190	hsa-miR-4420	CLIP-seq
MIRT922191	hsa-miR-4433	CLIP-seq
MIRT922192	hsa-miR-4447	CLIP-seq
MIRT922193	hsa-miR-4459	CLIP-seq
MIRT922194	hsa-miR-4472	CLIP-seq
MIRT922195	hsa-miR-4478	CLIP-seq
MIRT922196	hsa-miR-4505	CLIP-seq
MIRT922197	hsa-miR-4515	CLIP-seq
MIRT922198	hsa-miR-4525	CLIP-seq
MIRT922199	hsa-miR-4532	CLIP-seq
MIRT922200	hsa-miR-4633-3p	CLIP-seq
MIRT922201	hsa-miR-4634	CLIP-seq
MIRT922202	hsa-miR-4649-3p	CLIP-seq
MIRT922203	hsa-miR-4651	CLIP-seq
MIRT922204	hsa-miR-4665-5p	CLIP-seq
MIRT922205	hsa-miR-4671-5p	CLIP-seq
MIRT922206	hsa-miR-4687-3p	CLIP-seq
MIRT922207	hsa-miR-4720-5p	CLIP-seq
MIRT922208	hsa-miR-4722-5p	CLIP-seq
MIRT922209	hsa-miR-4723-5p	CLIP-seq
MIRT922210	hsa-miR-4728-3p	CLIP-seq
MIRT922211	hsa-miR-4736	CLIP-seq
MIRT922212	hsa-miR-4740-5p	CLIP-seq
MIRT922213	hsa-miR-4751	CLIP-seq
MIRT922214	hsa-miR-4758-3p	CLIP-seq
MIRT922215	hsa-miR-4763-3p	CLIP-seq
MIRT922216	hsa-miR-4763-5p	CLIP-seq
MIRT922217	hsa-miR-4768-3p	CLIP-seq
MIRT922218	hsa-miR-4779	CLIP-seq
MIRT922219	hsa-miR-4799-3p	CLIP-seq
MIRT922220	hsa-miR-485-5p	CLIP-seq
MIRT922221	hsa-miR-491-5p	CLIP-seq
MIRT922222	hsa-miR-493	CLIP-seq
MIRT922223	hsa-miR-520d-5p	CLIP-seq
MIRT922224	hsa-miR-524-5p	CLIP-seq
MIRT922225	hsa-miR-544b	CLIP-seq
MIRT922226	hsa-miR-569	CLIP-seq
MIRT922227	hsa-miR-608	CLIP-seq
MIRT922228	hsa-miR-625	CLIP-seq
MIRT922229	hsa-miR-647	CLIP-seq
MIRT922230	hsa-miR-652	CLIP-seq
MIRT922231	hsa-miR-760	CLIP-seq
MIRT922232	hsa-miR-764	CLIP-seq
MIRT922233	hsa-miR-9	CLIP-seq
MIRT922234	hsa-miR-940	CLIP-seq
MIRT1973136	hsa-miR-185	CLIP-seq
MIRT1973137	hsa-miR-3664-5p	CLIP-seq
MIRT1973138	hsa-miR-4287	CLIP-seq
MIRT1973139	hsa-miR-4306	CLIP-seq
MIRT1973140	hsa-miR-4469	CLIP-seq
MIRT1973141	hsa-miR-4644	CLIP-seq
MIRT1973142	hsa-miR-4685-3p	CLIP-seq
MIRT1973143	hsa-miR-4713-5p	CLIP-seq
MIRT922221	hsa-miR-491-5p	CLIP-seq
MIRT1973144	hsa-miR-548aa	CLIP-seq
MIRT2208791	hsa-miR-1	CLIP-seq
MIRT2208792	hsa-miR-1233	CLIP-seq
MIRT2208793	hsa-miR-129-3p	CLIP-seq
MIRT2208794	hsa-miR-133a	CLIP-seq
MIRT2208795	hsa-miR-133b	CLIP-seq
MIRT2208796	hsa-miR-1908	CLIP-seq
MIRT2208797	hsa-miR-1915	CLIP-seq
MIRT2208798	hsa-miR-1976	CLIP-seq
MIRT922151	hsa-miR-2053	CLIP-seq
MIRT2208799	hsa-miR-206	CLIP-seq
MIRT2208800	hsa-miR-2110	CLIP-seq
MIRT2208801	hsa-miR-2116	CLIP-seq
MIRT2208802	hsa-miR-2355-3p	CLIP-seq
MIRT2208803	hsa-miR-28-5p	CLIP-seq
MIRT922157	hsa-miR-3133	CLIP-seq
MIRT922158	hsa-miR-3134	CLIP-seq
MIRT2208804	hsa-miR-3139	CLIP-seq
MIRT2208805	hsa-miR-3144-5p	CLIP-seq
MIRT2208806	hsa-miR-3150a-3p	CLIP-seq
MIRT2208807	hsa-miR-3150b-3p	CLIP-seq
MIRT2208808	hsa-miR-3177-3p	CLIP-seq
MIRT2208809	hsa-miR-3187-3p	CLIP-seq
MIRT2208810	hsa-miR-3191	CLIP-seq
MIRT922165	hsa-miR-3192	CLIP-seq
MIRT2208811	hsa-miR-323b-5p	CLIP-seq
MIRT922169	hsa-miR-330-3p	CLIP-seq
MIRT2208812	hsa-miR-3652	CLIP-seq
MIRT2208813	hsa-miR-3673	CLIP-seq
MIRT2208814	hsa-miR-3692	CLIP-seq
MIRT2208815	hsa-miR-3909	CLIP-seq
MIRT2208816	hsa-miR-3922-5p	CLIP-seq
MIRT2208817	hsa-miR-4260	CLIP-seq
MIRT2208818	hsa-miR-4267	CLIP-seq
MIRT2208819	hsa-miR-4273	CLIP-seq
MIRT1973138	hsa-miR-4287	CLIP-seq
MIRT2208820	hsa-miR-4430	CLIP-seq
MIRT922191	hsa-miR-4433	CLIP-seq
MIRT2208821	hsa-miR-4435	CLIP-seq
MIRT2208822	hsa-miR-4453	CLIP-seq
MIRT922193	hsa-miR-4459	CLIP-seq
MIRT1973140	hsa-miR-4469	CLIP-seq
MIRT2208823	hsa-miR-4480	CLIP-seq
MIRT2208824	hsa-miR-4538	CLIP-seq
MIRT922200	hsa-miR-4633-3p	CLIP-seq
MIRT2208825	hsa-miR-4652-5p	CLIP-seq
MIRT2208826	hsa-miR-4677-5p	CLIP-seq
MIRT1973142	hsa-miR-4685-3p	CLIP-seq
MIRT2208827	hsa-miR-4689	CLIP-seq
MIRT2208828	hsa-miR-4701-5p	CLIP-seq
MIRT2208829	hsa-miR-4713-3p	CLIP-seq
MIRT1973143	hsa-miR-4713-5p	CLIP-seq
MIRT2208830	hsa-miR-4722-3p	CLIP-seq
MIRT922217	hsa-miR-4768-3p	CLIP-seq
MIRT2208831	hsa-miR-4773	CLIP-seq
MIRT2208832	hsa-miR-4775	CLIP-seq
MIRT2208833	hsa-miR-4784	CLIP-seq
MIRT2208834	hsa-miR-4786-5p	CLIP-seq
MIRT2208835	hsa-miR-4789-3p	CLIP-seq
MIRT922223	hsa-miR-520d-5p	CLIP-seq
MIRT922224	hsa-miR-524-5p	CLIP-seq
MIRT922225	hsa-miR-544b	CLIP-seq
MIRT2208836	hsa-miR-548s	CLIP-seq
MIRT922226	hsa-miR-569	CLIP-seq
MIRT2208837	hsa-miR-588	CLIP-seq
MIRT2208838	hsa-miR-613	CLIP-seq
MIRT2208839	hsa-miR-615-5p	CLIP-seq
MIRT922230	hsa-miR-652	CLIP-seq
MIRT2208840	hsa-miR-663	CLIP-seq
MIRT2208841	hsa-miR-676	CLIP-seq
MIRT2208842	hsa-miR-708	CLIP-seq
MIRT2208843	hsa-miR-744	CLIP-seq
MIRT2208844	hsa-miR-766	CLIP-seq
MIRT922233	hsa-miR-9	CLIP-seq
MIRT2208845	hsa-miR-938	CLIP-seq
MIRT922147	hsa-miR-1913	CLIP-seq
MIRT2208798	hsa-miR-1976	CLIP-seq
MIRT922167	hsa-miR-324-3p	CLIP-seq
MIRT2208830	hsa-miR-4722-3p	CLIP-seq
MIRT2386682	hsa-miR-4749-3p	CLIP-seq
MIRT2447964	hsa-miR-3613-3p	CLIP-seq
MIRT2447965	hsa-miR-3672	CLIP-seq
MIRT2447966	hsa-miR-371-5p	CLIP-seq
MIRT2447967	hsa-miR-371b-5p	CLIP-seq
MIRT1973140	hsa-miR-4469	CLIP-seq
MIRT2447968	hsa-miR-642a	CLIP-seq
MIRT2447964	hsa-miR-3613-3p	CLIP-seq
MIRT2447965	hsa-miR-3672	CLIP-seq
MIRT2447966	hsa-miR-371-5p	CLIP-seq
MIRT2447967	hsa-miR-371b-5p	CLIP-seq
MIRT1973140	hsa-miR-4469	CLIP-seq
MIRT2447968	hsa-miR-642a	CLIP-seq
MIRT922137	hsa-miR-1224-5p	CLIP-seq
MIRT2512619	hsa-miR-1225-5p	CLIP-seq
MIRT922138	hsa-miR-1228	CLIP-seq
MIRT2512620	hsa-miR-124	CLIP-seq
MIRT2512621	hsa-miR-216a	CLIP-seq
MIRT2208802	hsa-miR-2355-3p	CLIP-seq
MIRT922152	hsa-miR-24	CLIP-seq
MIRT922153	hsa-miR-2467-5p	CLIP-seq
MIRT2512622	hsa-miR-3064-3p	CLIP-seq
MIRT922154	hsa-miR-3122	CLIP-seq
MIRT922158	hsa-miR-3134	CLIP-seq
MIRT2512623	hsa-miR-3174	CLIP-seq
MIRT2208809	hsa-miR-3187-3p	CLIP-seq
MIRT922164	hsa-miR-3188	CLIP-seq
MIRT2208811	hsa-miR-323b-5p	CLIP-seq
MIRT922169	hsa-miR-330-3p	CLIP-seq
MIRT2512624	hsa-miR-3591-5p	CLIP-seq
MIRT2512625	hsa-miR-3606	CLIP-seq
MIRT2512626	hsa-miR-3609	CLIP-seq
MIRT2447964	hsa-miR-3613-3p	CLIP-seq
MIRT2447965	hsa-miR-3672	CLIP-seq
MIRT2512627	hsa-miR-3714	CLIP-seq
MIRT2447966	hsa-miR-371-5p	CLIP-seq
MIRT2447967	hsa-miR-371b-5p	CLIP-seq
MIRT2208815	hsa-miR-3909	CLIP-seq
MIRT2512628	hsa-miR-3910	CLIP-seq
MIRT922175	hsa-miR-3913-5p	CLIP-seq
MIRT2512629	hsa-miR-3926	CLIP-seq
MIRT922176	hsa-miR-3929	CLIP-seq
MIRT922179	hsa-miR-3975	CLIP-seq
MIRT2512630	hsa-miR-4283	CLIP-seq
MIRT922181	hsa-miR-4284	CLIP-seq
MIRT922187	hsa-miR-4329	CLIP-seq
MIRT922189	hsa-miR-4419b	CLIP-seq
MIRT922191	hsa-miR-4433	CLIP-seq
MIRT2208821	hsa-miR-4435	CLIP-seq
MIRT2208822	hsa-miR-4453	CLIP-seq
MIRT922193	hsa-miR-4459	CLIP-seq
MIRT1973140	hsa-miR-4469	CLIP-seq
MIRT922195	hsa-miR-4478	CLIP-seq
MIRT2512631	hsa-miR-4489	CLIP-seq
MIRT2208824	hsa-miR-4538	CLIP-seq
MIRT922202	hsa-miR-4649-3p	CLIP-seq
MIRT2512632	hsa-miR-4684-5p	CLIP-seq
MIRT2208828	hsa-miR-4701-5p	CLIP-seq
MIRT922213	hsa-miR-4751	CLIP-seq
MIRT922217	hsa-miR-4768-3p	CLIP-seq
MIRT2208834	hsa-miR-4786-5p	CLIP-seq
MIRT922220	hsa-miR-485-5p	CLIP-seq
MIRT2512633	hsa-miR-506	CLIP-seq
MIRT2512634	hsa-miR-520g	CLIP-seq
MIRT2512635	hsa-miR-520h	CLIP-seq
MIRT922225	hsa-miR-544b	CLIP-seq
MIRT2512636	hsa-miR-548ah	CLIP-seq
MIRT2512637	hsa-miR-548c-3p	CLIP-seq
MIRT2208836	hsa-miR-548s	CLIP-seq
MIRT2208837	hsa-miR-588	CLIP-seq
MIRT2512638	hsa-miR-590-3p	CLIP-seq
MIRT2447968	hsa-miR-642a	CLIP-seq
MIRT2208841	hsa-miR-676	CLIP-seq
MIRT2512639	hsa-miR-921	CLIP-seq
MIRT922234	hsa-miR-940	CLIP-seq
MIRT922137	hsa-miR-1224-5p	CLIP-seq
MIRT2512619	hsa-miR-1225-5p	CLIP-seq
MIRT922138	hsa-miR-1228	CLIP-seq
MIRT922143	hsa-miR-142-5p	CLIP-seq
MIRT2512621	hsa-miR-216a	CLIP-seq
MIRT2512622	hsa-miR-3064-3p	CLIP-seq
MIRT922154	hsa-miR-3122	CLIP-seq
MIRT922158	hsa-miR-3134	CLIP-seq
MIRT922170	hsa-miR-340	CLIP-seq
MIRT2512626	hsa-miR-3609	CLIP-seq
MIRT2447964	hsa-miR-3613-3p	CLIP-seq
MIRT2447965	hsa-miR-3672	CLIP-seq
MIRT2447966	hsa-miR-371-5p	CLIP-seq
MIRT2447967	hsa-miR-371b-5p	CLIP-seq
MIRT922175	hsa-miR-3913-5p	CLIP-seq
MIRT922176	hsa-miR-3929	CLIP-seq
MIRT2512630	hsa-miR-4283	CLIP-seq
MIRT922187	hsa-miR-4329	CLIP-seq
MIRT922189	hsa-miR-4419b	CLIP-seq
MIRT922191	hsa-miR-4433	CLIP-seq
MIRT922193	hsa-miR-4459	CLIP-seq
MIRT1973140	hsa-miR-4469	CLIP-seq
MIRT922195	hsa-miR-4478	CLIP-seq
MIRT2512631	hsa-miR-4489	CLIP-seq
MIRT922202	hsa-miR-4649-3p	CLIP-seq
MIRT2512632	hsa-miR-4684-5p	CLIP-seq
MIRT922213	hsa-miR-4751	CLIP-seq
MIRT922217	hsa-miR-4768-3p	CLIP-seq
MIRT922220	hsa-miR-485-5p	CLIP-seq
MIRT2512634	hsa-miR-520g	CLIP-seq
MIRT2512635	hsa-miR-520h	CLIP-seq
MIRT922225	hsa-miR-544b	CLIP-seq
MIRT2512636	hsa-miR-548ah	CLIP-seq
MIRT2512637	hsa-miR-548c-3p	CLIP-seq
MIRT2447968	hsa-miR-642a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	ISS
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	TAS	9417041
GO:0005515	Function	Protein binding	IPI	10198630, 14654833, 16027149, 16189514, 16415858, 17398095, 17563369, 22085542, 23143332, 25416956, 29420262, 29892012, 31022698, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IDA	17398095
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	17398095
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	9417041
GO:0005912	Component	Adherens junction	IEA
GO:0005923	Component	Bicellular tight junction	IEA
GO:0006897	Process	Endocytosis	TAS	9417041
GO:0008289	Function	Lipid binding	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	9417041
GO:0030036	Process	Actin cytoskeleton organization	TAS	9417041
GO:0030426	Component	Growth cone	IEA
GO:0032012	Process	Regulation of ARF protein signal transduction	IEA
GO:0042995	Component	Cell projection	IEA
GO:0070161	Component	Anchoring junction	IEA
GO:0070679	Function	Inositol 1,4,5 trisphosphate binding	ISS

Other IDs

• MIM: 602488
• HGNC: 9502
• e!Ensembl: ENSG00000105443

Protein

• UniProt ID: Q99418
• Protein name: Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
• Protein function: Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity). The cell membrane form, in association with ARL4 proteins
• PDB: 1PBV, 1R8M, 1R8Q, 1R8S, 1S9D, 4JMI, 4JMO, 4JWL, 4JXH, 4L5M, 4Z21
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01369	Sec7	61 → 243	Sec7 domain	Domain
  PF00169	PH	260 → 376	PH domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. {ECO:0000305|PubMed:9417041}.
• Sequence:

  MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTLQ
  RNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREE
  LNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQ
  STDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRN
  EPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEP
  RGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPT
  QEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP

• Sequence length: 400

Pathways

KEGG:

Phospholipase D signaling pathway
Endocytosis
Pathogenic Escherichia coli infection
Shigellosis
Salmonella infection

Reactome:

Intra-Golgi traffic

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
IGA GLOMERULONEPHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma of lung	Lung carcinoma	BEFREE	23545718		★☆☆☆☆ Found in Text Mining only
Cirrhosis	Cirrhosis	BEFREE	31758243		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	24618737		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37728516	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms Hereditary Nonpolyposis	Lynch syndrome	Pubtator	37728516	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	37728516	Associate	★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	30355448	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	23545718		★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver Cirrhosis	BEFREE	31758243		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	23545718		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	37577760	Associate	★☆☆☆☆ Found in Text Mining only