MAPKAPK2 (MAPK activated protein kinase 2)

Gene

• Entrez ID: 9261
• Gene name: MAPK activated protein kinase 2
• Gene symbol: MAPKAPK2
• Synonyms (NCBI Gene): MAPKAP-K2, MK-2, MK2
• Chromosome: 1
• Chromosome location: 1q32.1
• Summary: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022202	hsa-miR-124-3p	Microarray	18668037
MIRT043144	hsa-miR-324-5p	CLASH	23622248
MIRT043144	hsa-miR-324-5p	CLASH	23622248
MIRT041511	hsa-miR-193b-3p	CLASH	23622248
MIRT040005	hsa-miR-615-3p	CLASH	23622248
MIRT040005	hsa-miR-615-3p	CLASH	23622248
MIRT036373	hsa-miR-1229-3p	CLASH	23622248
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23313552
MIRT612780	hsa-miR-8485	HITS-CLIP	23313552
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23313552
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT675949	hsa-miR-8064	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT675949	hsa-miR-8064	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT132831	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT132834	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT132832	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT132836	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT616950	hsa-miR-1231	HITS-CLIP	27418678
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	27418678
MIRT616952	hsa-miR-4288	HITS-CLIP	27418678
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	27418678
MIRT612781	hsa-miR-483-3p	HITS-CLIP	27418678
MIRT616951	hsa-miR-632	HITS-CLIP	27418678
MIRT675949	hsa-miR-8064	HITS-CLIP	27418678
MIRT612780	hsa-miR-8485	HITS-CLIP	27418678
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23313552
MIRT612780	hsa-miR-8485	HITS-CLIP	23313552
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23313552
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23313552
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT675949	hsa-miR-8064	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT675949	hsa-miR-8064	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT616952	hsa-miR-4288	HITS-CLIP	23824327
MIRT616951	hsa-miR-632	HITS-CLIP	23824327
MIRT616950	hsa-miR-1231	HITS-CLIP	23824327
MIRT612781	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT612780	hsa-miR-8485	HITS-CLIP	23824327
MIRT612779	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT612778	hsa-miR-3680-5p	HITS-CLIP	23824327
MIRT1131417	hsa-miR-1236	CLIP-seq
MIRT1131418	hsa-miR-1827	CLIP-seq
MIRT1131419	hsa-miR-185	CLIP-seq
MIRT1131420	hsa-miR-298	CLIP-seq
MIRT1131421	hsa-miR-3120-5p	CLIP-seq
MIRT1131422	hsa-miR-3138	CLIP-seq
MIRT1131423	hsa-miR-3150b-3p	CLIP-seq
MIRT1131424	hsa-miR-3612	CLIP-seq
MIRT1131425	hsa-miR-3680	CLIP-seq
MIRT1131426	hsa-miR-4277	CLIP-seq
MIRT1131427	hsa-miR-4306	CLIP-seq
MIRT1131428	hsa-miR-4491	CLIP-seq
MIRT1131429	hsa-miR-4520a-3p	CLIP-seq
MIRT1131430	hsa-miR-4644	CLIP-seq
MIRT1131431	hsa-miR-4657	CLIP-seq
MIRT1131432	hsa-miR-4689	CLIP-seq
MIRT1131433	hsa-miR-4695-5p	CLIP-seq
MIRT1131434	hsa-miR-4784	CLIP-seq
MIRT1131435	hsa-miR-4800-5p	CLIP-seq
MIRT1131436	hsa-miR-576-3p	CLIP-seq
MIRT1131437	hsa-miR-593	CLIP-seq
MIRT1131438	hsa-miR-650	CLIP-seq
MIRT1131439	hsa-miR-765	CLIP-seq
MIRT1131440	hsa-miR-922	CLIP-seq
MIRT1131441	hsa-miR-125a-5p	CLIP-seq
MIRT1131442	hsa-miR-125b	CLIP-seq
MIRT1131443	hsa-miR-1270	CLIP-seq
MIRT1131444	hsa-miR-1287	CLIP-seq
MIRT1131445	hsa-miR-1301	CLIP-seq
MIRT1131446	hsa-miR-1913	CLIP-seq
MIRT1131447	hsa-miR-22	CLIP-seq
MIRT1131448	hsa-miR-3125	CLIP-seq
MIRT1131449	hsa-miR-3126-5p	CLIP-seq
MIRT1131450	hsa-miR-3135b	CLIP-seq
MIRT1131451	hsa-miR-3136-3p	CLIP-seq
MIRT1131423	hsa-miR-3150b-3p	CLIP-seq
MIRT1131452	hsa-miR-3155	CLIP-seq
MIRT1131453	hsa-miR-3155b	CLIP-seq
MIRT1131454	hsa-miR-3160-3p	CLIP-seq
MIRT1131455	hsa-miR-3189-5p	CLIP-seq
MIRT1131456	hsa-miR-324-3p	CLIP-seq
MIRT1131457	hsa-miR-329	CLIP-seq
MIRT1131458	hsa-miR-3616-3p	CLIP-seq
MIRT1131459	hsa-miR-362-3p	CLIP-seq
MIRT1131460	hsa-miR-3916	CLIP-seq
MIRT1131461	hsa-miR-4284	CLIP-seq
MIRT1131462	hsa-miR-4319	CLIP-seq
MIRT1131463	hsa-miR-4419a	CLIP-seq
MIRT1131464	hsa-miR-4434	CLIP-seq
MIRT1131465	hsa-miR-4436a	CLIP-seq
MIRT1131466	hsa-miR-4486	CLIP-seq
MIRT1131467	hsa-miR-4487	CLIP-seq
MIRT1131468	hsa-miR-4510	CLIP-seq
MIRT1131469	hsa-miR-4516	CLIP-seq
MIRT1131470	hsa-miR-4531	CLIP-seq
MIRT1131471	hsa-miR-4638-3p	CLIP-seq
MIRT1131472	hsa-miR-4641	CLIP-seq
MIRT1131473	hsa-miR-4645-5p	CLIP-seq
MIRT1131474	hsa-miR-4649-3p	CLIP-seq
MIRT1131475	hsa-miR-4660	CLIP-seq
MIRT1131476	hsa-miR-4673	CLIP-seq
MIRT1131477	hsa-miR-4683	CLIP-seq
MIRT1131432	hsa-miR-4689	CLIP-seq
MIRT1131478	hsa-miR-4709-5p	CLIP-seq
MIRT1131479	hsa-miR-4721	CLIP-seq
MIRT1131480	hsa-miR-4749-3p	CLIP-seq
MIRT1131481	hsa-miR-4758-3p	CLIP-seq
MIRT1131434	hsa-miR-4784	CLIP-seq
MIRT1131482	hsa-miR-484	CLIP-seq
MIRT1131483	hsa-miR-485-3p	CLIP-seq
MIRT1131484	hsa-miR-5047	CLIP-seq
MIRT1131485	hsa-miR-512-3p	CLIP-seq
MIRT1131486	hsa-miR-539	CLIP-seq
MIRT1131487	hsa-miR-544b	CLIP-seq
MIRT1131488	hsa-miR-548u	CLIP-seq
MIRT1131489	hsa-miR-556-5p	CLIP-seq
MIRT1131490	hsa-miR-558	CLIP-seq
MIRT1131491	hsa-miR-620	CLIP-seq
MIRT1131492	hsa-miR-654-3p	CLIP-seq
MIRT1131493	hsa-miR-663b	CLIP-seq
MIRT2037399	hsa-miR-1205	CLIP-seq
MIRT1131441	hsa-miR-125a-5p	CLIP-seq
MIRT1131442	hsa-miR-125b	CLIP-seq
MIRT1131443	hsa-miR-1270	CLIP-seq
MIRT2037400	hsa-miR-1321	CLIP-seq
MIRT1131446	hsa-miR-1913	CLIP-seq
MIRT2037401	hsa-miR-219-1-3p	CLIP-seq
MIRT2037402	hsa-miR-24	CLIP-seq
MIRT2037403	hsa-miR-3121-5p	CLIP-seq
MIRT1131448	hsa-miR-3125	CLIP-seq
MIRT1131449	hsa-miR-3126-5p	CLIP-seq
MIRT2037404	hsa-miR-3154	CLIP-seq
MIRT1131452	hsa-miR-3155	CLIP-seq
MIRT1131453	hsa-miR-3155b	CLIP-seq
MIRT2037405	hsa-miR-3186-5p	CLIP-seq
MIRT1131456	hsa-miR-324-3p	CLIP-seq
MIRT1131457	hsa-miR-329	CLIP-seq
MIRT2037406	hsa-miR-361-3p	CLIP-seq
MIRT1131458	hsa-miR-3616-3p	CLIP-seq
MIRT1131459	hsa-miR-362-3p	CLIP-seq
MIRT2037407	hsa-miR-3670	CLIP-seq
MIRT2037408	hsa-miR-3679-3p	CLIP-seq
MIRT1131425	hsa-miR-3680	CLIP-seq
MIRT2037409	hsa-miR-3692	CLIP-seq
MIRT2037410	hsa-miR-3714	CLIP-seq
MIRT1131460	hsa-miR-3916	CLIP-seq
MIRT2037411	hsa-miR-3941	CLIP-seq
MIRT2037412	hsa-miR-425	CLIP-seq
MIRT2037413	hsa-miR-4257	CLIP-seq
MIRT2037414	hsa-miR-4269	CLIP-seq
MIRT1131461	hsa-miR-4284	CLIP-seq
MIRT2037415	hsa-miR-4297	CLIP-seq
MIRT2037416	hsa-miR-4299	CLIP-seq
MIRT1131462	hsa-miR-4319	CLIP-seq
MIRT1131463	hsa-miR-4419a	CLIP-seq
MIRT2037417	hsa-miR-4420	CLIP-seq
MIRT1131464	hsa-miR-4434	CLIP-seq
MIRT2037418	hsa-miR-4436b-3p	CLIP-seq
MIRT2037419	hsa-miR-4456	CLIP-seq
MIRT2037420	hsa-miR-4476	CLIP-seq
MIRT1131466	hsa-miR-4486	CLIP-seq
MIRT1131468	hsa-miR-4510	CLIP-seq
MIRT1131469	hsa-miR-4516	CLIP-seq
MIRT2037421	hsa-miR-4642	CLIP-seq
MIRT2037422	hsa-miR-4645-3p	CLIP-seq
MIRT1131474	hsa-miR-4649-3p	CLIP-seq
MIRT2037423	hsa-miR-4682	CLIP-seq
MIRT1131477	hsa-miR-4683	CLIP-seq
MIRT2037424	hsa-miR-4687-3p	CLIP-seq
MIRT2037425	hsa-miR-4691-5p	CLIP-seq
MIRT2037426	hsa-miR-4704-3p	CLIP-seq
MIRT2037427	hsa-miR-4706	CLIP-seq
MIRT2037428	hsa-miR-4719	CLIP-seq
MIRT1131479	hsa-miR-4721	CLIP-seq
MIRT2037429	hsa-miR-4723-5p	CLIP-seq
MIRT2037430	hsa-miR-4728-5p	CLIP-seq
MIRT2037431	hsa-miR-4731-5p	CLIP-seq
MIRT2037432	hsa-miR-4739	CLIP-seq
MIRT1131480	hsa-miR-4749-3p	CLIP-seq
MIRT2037433	hsa-miR-4749-5p	CLIP-seq
MIRT2037434	hsa-miR-4751	CLIP-seq
MIRT2037435	hsa-miR-4752	CLIP-seq
MIRT2037436	hsa-miR-4756-5p	CLIP-seq
MIRT2037437	hsa-miR-4761-5p	CLIP-seq
MIRT2037438	hsa-miR-4781-5p	CLIP-seq
MIRT2037439	hsa-miR-4797-3p	CLIP-seq
MIRT1131482	hsa-miR-484	CLIP-seq
MIRT1131483	hsa-miR-485-3p	CLIP-seq
MIRT2037440	hsa-miR-495	CLIP-seq
MIRT2037441	hsa-miR-520a-5p	CLIP-seq
MIRT2037442	hsa-miR-525-5p	CLIP-seq
MIRT1131487	hsa-miR-544b	CLIP-seq
MIRT2037443	hsa-miR-548q	CLIP-seq
MIRT2037444	hsa-miR-571	CLIP-seq
MIRT2037445	hsa-miR-603	CLIP-seq
MIRT1131491	hsa-miR-620	CLIP-seq
MIRT2037446	hsa-miR-634	CLIP-seq
MIRT2037447	hsa-miR-637	CLIP-seq
MIRT1131492	hsa-miR-654-3p	CLIP-seq
MIRT2267341	hsa-miR-1184	CLIP-seq
MIRT2037399	hsa-miR-1205	CLIP-seq
MIRT1131443	hsa-miR-1270	CLIP-seq
MIRT1131445	hsa-miR-1301	CLIP-seq
MIRT1131418	hsa-miR-1827	CLIP-seq
MIRT2267342	hsa-miR-1972	CLIP-seq
MIRT2037402	hsa-miR-24	CLIP-seq
MIRT2267343	hsa-miR-31	CLIP-seq
MIRT1131448	hsa-miR-3125	CLIP-seq
MIRT1131423	hsa-miR-3150b-3p	CLIP-seq
MIRT2037404	hsa-miR-3154	CLIP-seq
MIRT1131452	hsa-miR-3155	CLIP-seq
MIRT1131453	hsa-miR-3155b	CLIP-seq
MIRT2267344	hsa-miR-3158-5p	CLIP-seq
MIRT2267345	hsa-miR-3173-5p	CLIP-seq
MIRT2267346	hsa-miR-3179	CLIP-seq
MIRT2267347	hsa-miR-3183	CLIP-seq
MIRT2267348	hsa-miR-326	CLIP-seq
MIRT2267349	hsa-miR-330-5p	CLIP-seq
MIRT2267350	hsa-miR-342-5p	CLIP-seq
MIRT1131424	hsa-miR-3612	CLIP-seq
MIRT1131458	hsa-miR-3616-3p	CLIP-seq
MIRT2037410	hsa-miR-3714	CLIP-seq
MIRT1131460	hsa-miR-3916	CLIP-seq
MIRT2267351	hsa-miR-3976	CLIP-seq
MIRT2037414	hsa-miR-4269	CLIP-seq
MIRT2267352	hsa-miR-4271	CLIP-seq
MIRT1131461	hsa-miR-4284	CLIP-seq
MIRT2267353	hsa-miR-4287	CLIP-seq
MIRT1131463	hsa-miR-4419a	CLIP-seq
MIRT2037417	hsa-miR-4420	CLIP-seq
MIRT2267354	hsa-miR-4435	CLIP-seq
MIRT1131465	hsa-miR-4436a	CLIP-seq
MIRT2037418	hsa-miR-4436b-3p	CLIP-seq
MIRT2267355	hsa-miR-4469	CLIP-seq
MIRT1131428	hsa-miR-4491	CLIP-seq
MIRT1131468	hsa-miR-4510	CLIP-seq
MIRT2267356	hsa-miR-4512	CLIP-seq
MIRT2037421	hsa-miR-4642	CLIP-seq
MIRT1131473	hsa-miR-4645-5p	CLIP-seq
MIRT1131474	hsa-miR-4649-3p	CLIP-seq
MIRT1131431	hsa-miR-4657	CLIP-seq
MIRT1131475	hsa-miR-4660	CLIP-seq
MIRT2267357	hsa-miR-4664-5p	CLIP-seq
MIRT2267358	hsa-miR-4667-5p	CLIP-seq
MIRT1131476	hsa-miR-4673	CLIP-seq
MIRT1131477	hsa-miR-4683	CLIP-seq
MIRT2267359	hsa-miR-4685-3p	CLIP-seq
MIRT1131432	hsa-miR-4689	CLIP-seq
MIRT2037425	hsa-miR-4691-5p	CLIP-seq
MIRT1131433	hsa-miR-4695-5p	CLIP-seq
MIRT2267360	hsa-miR-4700-5p	CLIP-seq
MIRT2037426	hsa-miR-4704-3p	CLIP-seq
MIRT2267361	hsa-miR-4717-5p	CLIP-seq
MIRT1131479	hsa-miR-4721	CLIP-seq
MIRT2267362	hsa-miR-4723-3p	CLIP-seq
MIRT2267363	hsa-miR-4725-3p	CLIP-seq
MIRT2037437	hsa-miR-4761-5p	CLIP-seq
MIRT1131434	hsa-miR-4784	CLIP-seq
MIRT2037439	hsa-miR-4797-3p	CLIP-seq
MIRT1131482	hsa-miR-484	CLIP-seq
MIRT1131484	hsa-miR-5047	CLIP-seq
MIRT1131436	hsa-miR-576-3p	CLIP-seq
MIRT1131491	hsa-miR-620	CLIP-seq
MIRT2037447	hsa-miR-637	CLIP-seq
MIRT2267364	hsa-miR-642a	CLIP-seq
MIRT1131438	hsa-miR-650	CLIP-seq
MIRT1131492	hsa-miR-654-3p	CLIP-seq
MIRT1131439	hsa-miR-765	CLIP-seq
MIRT1131417	hsa-miR-1236	CLIP-seq
MIRT1131443	hsa-miR-1270	CLIP-seq
MIRT1131446	hsa-miR-1913	CLIP-seq
MIRT1131421	hsa-miR-3120-5p	CLIP-seq
MIRT1131448	hsa-miR-3125	CLIP-seq
MIRT1131456	hsa-miR-324-3p	CLIP-seq
MIRT1131458	hsa-miR-3616-3p	CLIP-seq
MIRT1131460	hsa-miR-3916	CLIP-seq
MIRT2037414	hsa-miR-4269	CLIP-seq
MIRT1131426	hsa-miR-4277	CLIP-seq
MIRT2390609	hsa-miR-4481	CLIP-seq
MIRT2037421	hsa-miR-4642	CLIP-seq
MIRT1131473	hsa-miR-4645-5p	CLIP-seq
MIRT1131474	hsa-miR-4649-3p	CLIP-seq
MIRT1131476	hsa-miR-4673	CLIP-seq
MIRT1131477	hsa-miR-4683	CLIP-seq
MIRT2037425	hsa-miR-4691-5p	CLIP-seq
MIRT1131479	hsa-miR-4721	CLIP-seq
MIRT2390610	hsa-miR-4745-5p	CLIP-seq
MIRT1131480	hsa-miR-4749-3p	CLIP-seq
MIRT2037437	hsa-miR-4761-5p	CLIP-seq
MIRT1131437	hsa-miR-593	CLIP-seq
MIRT1131491	hsa-miR-620	CLIP-seq
MIRT1131492	hsa-miR-654-3p	CLIP-seq
MIRT2037406	hsa-miR-361-3p	CLIP-seq
MIRT2037408	hsa-miR-3679-3p	CLIP-seq
MIRT2037415	hsa-miR-4297	CLIP-seq
MIRT2438512	hsa-miR-4731-3p	CLIP-seq
MIRT2438513	hsa-miR-4738-5p	CLIP-seq
MIRT2438514	hsa-miR-4801	CLIP-seq
MIRT1131441	hsa-miR-125a-5p	CLIP-seq
MIRT1131442	hsa-miR-125b	CLIP-seq
MIRT1131446	hsa-miR-1913	CLIP-seq
MIRT1131456	hsa-miR-324-3p	CLIP-seq
MIRT1131462	hsa-miR-4319	CLIP-seq
MIRT1131480	hsa-miR-4749-3p	CLIP-seq
MIRT1131487	hsa-miR-544b	CLIP-seq
MIRT2037399	hsa-miR-1205	CLIP-seq
MIRT1131441	hsa-miR-125a-5p	CLIP-seq
MIRT1131442	hsa-miR-125b	CLIP-seq
MIRT2567112	hsa-miR-1275	CLIP-seq
MIRT2567113	hsa-miR-1291	CLIP-seq
MIRT2037400	hsa-miR-1321	CLIP-seq
MIRT2567114	hsa-miR-1324	CLIP-seq
MIRT2567115	hsa-miR-1470	CLIP-seq
MIRT2567116	hsa-miR-183	CLIP-seq
MIRT1131446	hsa-miR-1913	CLIP-seq
MIRT2267342	hsa-miR-1972	CLIP-seq
MIRT2037401	hsa-miR-219-1-3p	CLIP-seq
MIRT1131447	hsa-miR-22	CLIP-seq
MIRT2037403	hsa-miR-3121-5p	CLIP-seq
MIRT1131448	hsa-miR-3125	CLIP-seq
MIRT1131449	hsa-miR-3126-5p	CLIP-seq
MIRT1131451	hsa-miR-3136-3p	CLIP-seq
MIRT1131452	hsa-miR-3155	CLIP-seq
MIRT1131453	hsa-miR-3155b	CLIP-seq
MIRT1131454	hsa-miR-3160-3p	CLIP-seq
MIRT2567117	hsa-miR-3170	CLIP-seq
MIRT2267345	hsa-miR-3173-5p	CLIP-seq
MIRT2567118	hsa-miR-3178	CLIP-seq
MIRT2267346	hsa-miR-3179	CLIP-seq
MIRT2567119	hsa-miR-3194-3p	CLIP-seq
MIRT2567120	hsa-miR-3197	CLIP-seq
MIRT2567121	hsa-miR-3200-5p	CLIP-seq
MIRT2567122	hsa-miR-3202	CLIP-seq
MIRT1131456	hsa-miR-324-3p	CLIP-seq
MIRT2567123	hsa-miR-328	CLIP-seq
MIRT1131457	hsa-miR-329	CLIP-seq
MIRT2267350	hsa-miR-342-5p	CLIP-seq
MIRT2037406	hsa-miR-361-3p	CLIP-seq
MIRT1131459	hsa-miR-362-3p	CLIP-seq
MIRT2567124	hsa-miR-3677-5p	CLIP-seq
MIRT2037408	hsa-miR-3679-3p	CLIP-seq
MIRT2567125	hsa-miR-3688-3p	CLIP-seq
MIRT1131460	hsa-miR-3916	CLIP-seq
MIRT2567126	hsa-miR-3936	CLIP-seq
MIRT2567127	hsa-miR-4251	CLIP-seq
MIRT2567128	hsa-miR-4260	CLIP-seq
MIRT2567129	hsa-miR-4268	CLIP-seq
MIRT2037414	hsa-miR-4269	CLIP-seq
MIRT1131461	hsa-miR-4284	CLIP-seq
MIRT2267353	hsa-miR-4287	CLIP-seq
MIRT2567130	hsa-miR-4292	CLIP-seq
MIRT2037415	hsa-miR-4297	CLIP-seq
MIRT1131462	hsa-miR-4319	CLIP-seq
MIRT2567131	hsa-miR-4329	CLIP-seq
MIRT1131463	hsa-miR-4419a	CLIP-seq
MIRT2567132	hsa-miR-4447	CLIP-seq
MIRT2567133	hsa-miR-4448	CLIP-seq
MIRT2567134	hsa-miR-4457	CLIP-seq
MIRT2267355	hsa-miR-4469	CLIP-seq
MIRT2567135	hsa-miR-4470	CLIP-seq
MIRT2567136	hsa-miR-4472	CLIP-seq
MIRT2390609	hsa-miR-4481	CLIP-seq
MIRT1131466	hsa-miR-4486	CLIP-seq
MIRT1131467	hsa-miR-4487	CLIP-seq
MIRT1131468	hsa-miR-4510	CLIP-seq
MIRT2567137	hsa-miR-4525	CLIP-seq
MIRT1131474	hsa-miR-4649-3p	CLIP-seq
MIRT2267357	hsa-miR-4664-5p	CLIP-seq
MIRT2567138	hsa-miR-4665-5p	CLIP-seq
MIRT2567139	hsa-miR-4667-3p	CLIP-seq
MIRT2037423	hsa-miR-4682	CLIP-seq
MIRT2267359	hsa-miR-4685-3p	CLIP-seq
MIRT2567140	hsa-miR-4715-3p	CLIP-seq
MIRT2567141	hsa-miR-4716-3p	CLIP-seq
MIRT2267361	hsa-miR-4717-5p	CLIP-seq
MIRT2037429	hsa-miR-4723-5p	CLIP-seq
MIRT2567142	hsa-miR-4725-5p	CLIP-seq
MIRT2567143	hsa-miR-4727-5p	CLIP-seq
MIRT2438512	hsa-miR-4731-3p	CLIP-seq
MIRT2037431	hsa-miR-4731-5p	CLIP-seq
MIRT2567144	hsa-miR-4733-3p	CLIP-seq
MIRT2438513	hsa-miR-4738-5p	CLIP-seq
MIRT2037432	hsa-miR-4739	CLIP-seq
MIRT2390610	hsa-miR-4745-5p	CLIP-seq
MIRT2567145	hsa-miR-4747-5p	CLIP-seq
MIRT1131480	hsa-miR-4749-3p	CLIP-seq
MIRT2037436	hsa-miR-4756-5p	CLIP-seq
MIRT2567146	hsa-miR-4769-3p	CLIP-seq
MIRT2567147	hsa-miR-4796-3p	CLIP-seq
MIRT2438514	hsa-miR-4801	CLIP-seq
MIRT1131482	hsa-miR-484	CLIP-seq
MIRT2567148	hsa-miR-504	CLIP-seq
MIRT1131487	hsa-miR-544b	CLIP-seq
MIRT2567149	hsa-miR-548t	CLIP-seq
MIRT1131488	hsa-miR-548u	CLIP-seq
MIRT1131489	hsa-miR-556-5p	CLIP-seq
MIRT1131490	hsa-miR-558	CLIP-seq
MIRT2037444	hsa-miR-571	CLIP-seq
MIRT2567150	hsa-miR-625	CLIP-seq
MIRT2037447	hsa-miR-637	CLIP-seq
MIRT1131493	hsa-miR-663b	CLIP-seq
MIRT2567151	hsa-miR-7	CLIP-seq
MIRT2037399	hsa-miR-1205	CLIP-seq
MIRT1131441	hsa-miR-125a-5p	CLIP-seq
MIRT1131442	hsa-miR-125b	CLIP-seq
MIRT2567112	hsa-miR-1275	CLIP-seq
MIRT2567113	hsa-miR-1291	CLIP-seq
MIRT2037400	hsa-miR-1321	CLIP-seq
MIRT2567114	hsa-miR-1324	CLIP-seq
MIRT2567115	hsa-miR-1470	CLIP-seq
MIRT2567116	hsa-miR-183	CLIP-seq
MIRT1131446	hsa-miR-1913	CLIP-seq
MIRT2267342	hsa-miR-1972	CLIP-seq
MIRT2037401	hsa-miR-219-1-3p	CLIP-seq
MIRT1131447	hsa-miR-22	CLIP-seq
MIRT2037403	hsa-miR-3121-5p	CLIP-seq
MIRT1131448	hsa-miR-3125	CLIP-seq
MIRT1131449	hsa-miR-3126-5p	CLIP-seq
MIRT1131451	hsa-miR-3136-3p	CLIP-seq
MIRT1131452	hsa-miR-3155	CLIP-seq
MIRT1131453	hsa-miR-3155b	CLIP-seq
MIRT1131454	hsa-miR-3160-3p	CLIP-seq
MIRT2567117	hsa-miR-3170	CLIP-seq
MIRT2267345	hsa-miR-3173-5p	CLIP-seq
MIRT2567118	hsa-miR-3178	CLIP-seq
MIRT2267346	hsa-miR-3179	CLIP-seq
MIRT2567119	hsa-miR-3194-3p	CLIP-seq
MIRT2567120	hsa-miR-3197	CLIP-seq
MIRT2567121	hsa-miR-3200-5p	CLIP-seq
MIRT2567122	hsa-miR-3202	CLIP-seq
MIRT1131456	hsa-miR-324-3p	CLIP-seq
MIRT2567123	hsa-miR-328	CLIP-seq
MIRT1131457	hsa-miR-329	CLIP-seq
MIRT2267350	hsa-miR-342-5p	CLIP-seq
MIRT2037406	hsa-miR-361-3p	CLIP-seq
MIRT1131459	hsa-miR-362-3p	CLIP-seq
MIRT2567124	hsa-miR-3677-5p	CLIP-seq
MIRT2037408	hsa-miR-3679-3p	CLIP-seq
MIRT2567125	hsa-miR-3688-3p	CLIP-seq
MIRT1131460	hsa-miR-3916	CLIP-seq
MIRT2567126	hsa-miR-3936	CLIP-seq
MIRT2567127	hsa-miR-4251	CLIP-seq
MIRT2567128	hsa-miR-4260	CLIP-seq
MIRT2567129	hsa-miR-4268	CLIP-seq
MIRT2037414	hsa-miR-4269	CLIP-seq
MIRT1131461	hsa-miR-4284	CLIP-seq
MIRT2267353	hsa-miR-4287	CLIP-seq
MIRT2567130	hsa-miR-4292	CLIP-seq
MIRT2037415	hsa-miR-4297	CLIP-seq
MIRT1131462	hsa-miR-4319	CLIP-seq
MIRT2567131	hsa-miR-4329	CLIP-seq
MIRT1131463	hsa-miR-4419a	CLIP-seq
MIRT1131464	hsa-miR-4434	CLIP-seq
MIRT2567132	hsa-miR-4447	CLIP-seq
MIRT2567133	hsa-miR-4448	CLIP-seq
MIRT2567134	hsa-miR-4457	CLIP-seq
MIRT2267355	hsa-miR-4469	CLIP-seq
MIRT2567135	hsa-miR-4470	CLIP-seq
MIRT2567136	hsa-miR-4472	CLIP-seq
MIRT2390609	hsa-miR-4481	CLIP-seq
MIRT1131466	hsa-miR-4486	CLIP-seq
MIRT1131467	hsa-miR-4487	CLIP-seq
MIRT1131468	hsa-miR-4510	CLIP-seq
MIRT1131469	hsa-miR-4516	CLIP-seq
MIRT2567137	hsa-miR-4525	CLIP-seq
MIRT1131470	hsa-miR-4531	CLIP-seq
MIRT1131472	hsa-miR-4641	CLIP-seq
MIRT1131474	hsa-miR-4649-3p	CLIP-seq
MIRT2267357	hsa-miR-4664-5p	CLIP-seq
MIRT2567138	hsa-miR-4665-5p	CLIP-seq
MIRT2567139	hsa-miR-4667-3p	CLIP-seq
MIRT2037423	hsa-miR-4682	CLIP-seq
MIRT2267359	hsa-miR-4685-3p	CLIP-seq
MIRT2567140	hsa-miR-4715-3p	CLIP-seq
MIRT2567141	hsa-miR-4716-3p	CLIP-seq
MIRT2267361	hsa-miR-4717-5p	CLIP-seq
MIRT2037429	hsa-miR-4723-5p	CLIP-seq
MIRT2567142	hsa-miR-4725-5p	CLIP-seq
MIRT2567143	hsa-miR-4727-5p	CLIP-seq
MIRT2438512	hsa-miR-4731-3p	CLIP-seq
MIRT2037431	hsa-miR-4731-5p	CLIP-seq
MIRT2567144	hsa-miR-4733-3p	CLIP-seq
MIRT2438513	hsa-miR-4738-5p	CLIP-seq
MIRT2037432	hsa-miR-4739	CLIP-seq
MIRT2390610	hsa-miR-4745-5p	CLIP-seq
MIRT2567145	hsa-miR-4747-5p	CLIP-seq
MIRT1131480	hsa-miR-4749-3p	CLIP-seq
MIRT2037436	hsa-miR-4756-5p	CLIP-seq
MIRT2567146	hsa-miR-4769-3p	CLIP-seq
MIRT2567147	hsa-miR-4796-3p	CLIP-seq
MIRT2438514	hsa-miR-4801	CLIP-seq
MIRT1131482	hsa-miR-484	CLIP-seq
MIRT2567148	hsa-miR-504	CLIP-seq
MIRT1131486	hsa-miR-539	CLIP-seq
MIRT1131487	hsa-miR-544b	CLIP-seq
MIRT2567149	hsa-miR-548t	CLIP-seq
MIRT1131488	hsa-miR-548u	CLIP-seq
MIRT1131489	hsa-miR-556-5p	CLIP-seq
MIRT1131490	hsa-miR-558	CLIP-seq
MIRT2037444	hsa-miR-571	CLIP-seq
MIRT2567150	hsa-miR-625	CLIP-seq
MIRT2037447	hsa-miR-637	CLIP-seq
MIRT1131493	hsa-miR-663b	CLIP-seq
MIRT2567151	hsa-miR-7	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IDA	15850461
GO:0000165	Process	MAPK cascade	IEA
GO:0000165	Process	MAPK cascade	TAS	8179591
GO:0000166	Function	Nucleotide binding	IEA
GO:0002224	Process	Toll-like receptor signaling pathway	IBA
GO:0002224	Process	Toll-like receptor signaling pathway	IEA
GO:0002224	Process	Toll-like receptor signaling pathway	ISS
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	8179591
GO:0004674	Function	Protein serine/threonine kinase activity	EXP	7799959, 16278218, 28506461, 28920952
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	8774846, 8846784, 14517288, 15014438, 15850461, 20932473, 24020373
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	TAS	8280084
GO:0004683	Function	Calcium/calmodulin-dependent protein kinase activity	IBA
GO:0005515	Function	Protein binding	IPI	8774846, 14517288, 15014438, 16278218, 17255097, 17395714, 19369945, 20932473, 21575178, 21988832, 23455922, 23602568, 25241761, 25852190, 26496610, 31980649, 32707033, 33961781, 35271311
GO:0005516	Function	Calmodulin binding	IBA
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	20932473
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	8280084
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	20932473
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006691	Process	Leukotriene metabolic process	TAS
GO:0006954	Process	Inflammatory response	IBA
GO:0006954	Process	Inflammatory response	IEA
GO:0006954	Process	Inflammatory response	ISS
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	IMP	20932473
GO:0009931	Function	Calcium-dependent protein serine/threonine kinase activity	IBA
GO:0010803	Process	Regulation of tumor necrosis factor-mediated signaling pathway	TAS
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0032496	Process	Response to lipopolysaccharide	ISS
GO:0032675	Process	Regulation of interleukin-6 production	IEA
GO:0032675	Process	Regulation of interleukin-6 production	ISS
GO:0032680	Process	Regulation of tumor necrosis factor production	IDA	15014438
GO:0032680	Process	Regulation of tumor necrosis factor production	IEA
GO:0032760	Process	Positive regulation of tumor necrosis factor production	IEA
GO:0034097	Process	Response to cytokine	IBA
GO:0034097	Process	Response to cytokine	IDA	8774846
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0035924	Process	Cellular response to vascular endothelial growth factor stimulus	IBA
GO:0035924	Process	Cellular response to vascular endothelial growth factor stimulus	IMP	18440775
GO:0036064	Component	Ciliary basal body	IDA
GO:0038066	Process	P38MAPK cascade	IEA
GO:0043488	Process	Regulation of mRNA stability	TAS
GO:0044351	Process	Macropinocytosis	IEA
GO:0044351	Process	Macropinocytosis	ISS
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	IBA
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	IEA
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	IMP	18440775
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	TAS
GO:0048255	Process	MRNA stabilization	IEA
GO:0048839	Process	Inner ear development	IEA
GO:0051019	Function	Mitogen-activated protein kinase binding	IBA
GO:0060907	Process	Positive regulation of macrophage cytokine production	IEA
GO:0070062	Component	Extracellular exosome	HDA	18570454
GO:0070935	Process	3'-UTR-mediated mRNA stabilization	IDA	14517288, 15014438, 20932473
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1900034	Process	Regulation of cellular response to heat	TAS

Other IDs

• MIM: 602006
• HGNC: 6887
• e!Ensembl: ENSG00000162889

Protein

• UniProt ID: P49137
• Protein name: MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)
• Protein function: Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Foll
• PDB: 1KWP, 1NXK, 1NY3, 2JBO, 2JBP, 2OKR, 2ONL, 2OZA, 2P3G, 2PZY, 3A2C, 3FPM, 3FYJ, 3FYK, 3GOK, 3KA0, 3KC3, 3KGA, 3M2W, 3M42, 3R2B, 3R2Y, 3R30, 3WI6, 4TYH, 6T8X, 6TCA, 7NRY, 8XU4, 8XX1
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	64 → 325	Protein kinase domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in all tissues examined.
• Sequence:

  MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
  DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
  VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
  NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
  DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
  LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
  ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH

• Sequence length: 400

Pathways

KEGG:

MAPK signaling pathway
Efferocytosis
Cellular senescence
VEGF signaling pathway
C-type lectin receptor signaling pathway
Neurotrophin signaling pathway
Kaposi sarcoma-associated herpesvirus infection
Viral carcinogenesis

Reactome:

p38MAPK events
CREB phosphorylation
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Oxidative Stress Induced Senescence
Regulation of HSF1-mediated heat shock response
VEGFA-VEGFR2 Pathway
activated TAK1 mediates p38 MAPK activation
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CROHN'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodevelopmental disorder	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma Of Esophagus	Esophageal Cancer	BEFREE	29483950		★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	24469230		★☆☆☆☆ Found in Text Mining only
Aortic Dissection	Aortic dissection	Pubtator	37684281	Associate	★☆☆☆☆ Found in Text Mining only
Arthritis Juvenile	Juvenile arthritis	Pubtator	23094074	Associate	★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	30112991		★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	20068172		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	12377770	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	22883146	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	20068172		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	22883146		★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	29844172		★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	BEFREE	30298062		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	29197088, 31575657		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	27107574, 31575657	Associate	★☆☆☆☆ Found in Text Mining only
Congenital Thrombotic Thrombocytopenic Purpura	Congenital Thrombotic Thrombocytopenic Purpura	BEFREE	31527197		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	18562219		★☆☆☆☆ Found in Text Mining only
Dry Eye Syndromes	Dry Eye Syndromes	BEFREE	28973340		★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	29483950		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	29483950		★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi Anemia	BEFREE	22234699		★☆☆☆☆ Found in Text Mining only
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	BEFREE	22234699		★☆☆☆☆ Found in Text Mining only
Gastrointestinal Neoplasms	Gastrointestinal neoplasm	Pubtator	32216812	Associate	★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	22351694		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	25088200		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	25088200		★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	31417185		★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Head and neck neoplasm	Pubtator	25019640	Associate	★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	30130411		★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	36611026	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	27619201		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	22883146	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Head and Neck Neoplasm	Head and neck cancer	BEFREE	31417185		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	29483950		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	26169728		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	22883146		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	26124331		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	16407830		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	20068172		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	16928813, 22883146, 24056810, 29704518, 29844172, 31440466		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	12377770		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	31622599	Associate	★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	37684281	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	19171422, 31440466		★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	40508046	Associate	★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	31269974	Associate	★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	24056810		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	24239348, 24356814, 29197088, 29844172, 30298062, 31023373, 31417185		★☆☆☆☆ Found in Text Mining only
Nephrotic Syndrome	Nephrotic Syndrome	BEFREE	29187369		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	25086905		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	32409685, 37116859	Associate	★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	24239348		★☆☆☆☆ Found in Text Mining only
Oral Ulcer	Oral Ulcer	GWASCAT_DG	30837455		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	18562219	Associate	★☆☆☆☆ Found in Text Mining only
Osteopenia	Osteopenia	BEFREE	27795356		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	39972314	Inhibit	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	26124331		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	24556918	Associate	★☆☆☆☆ Found in Text Mining only
Pemphigus Vulgaris	Pemphigus Vulgaris	BEFREE	23657501		★☆☆☆☆ Found in Text Mining only
Polyneuropathies	Polyneuropathy	Pubtator	40508046	Associate	★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	16407830		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	16407830		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	35328346	Associate	★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	16424170		★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	23470623, 30130411		★☆☆☆☆ Found in Text Mining only
Purpura, Thrombotic Thrombocytopenic	Thrombotic thrombocytopenic purpura	BEFREE	31527197		★☆☆☆☆ Found in Text Mining only
Respiratory Distress Syndrome, Adult	Respiratory Distress Syndrome	BEFREE	30112991		★☆☆☆☆ Found in Text Mining only
Sarcoma Kaposi	Sarcoma	Pubtator	23740979	Associate	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	25019640	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	31023373, 31417185		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	29661232, 32216812	Associate	★☆☆☆☆ Found in Text Mining only
Telomeric 22q13 Monosomy Syndrome	22q13 monosomy syndrome	Pubtator	25214013	Associate	★☆☆☆☆ Found in Text Mining only