CRLF1 (cytokine receptor like factor 1)

Gene

• Entrez ID: 9244
• Gene name: Cytokine receptor like factor 1
• Gene symbol: CRLF1
• Synonyms (NCBI Gene): CISS, CISS1, CLF, CLF-1, NR6, zcytor5
• Chromosome: 19
• Chromosome location: 19p13.11
• Summary: This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuro

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs104894668	A>C	Pathogenic	Coding sequence variant, missense variant
rs104894670	C>T	Benign, pathogenic	Coding sequence variant, missense variant
rs137853143	A>C,G	Pathogenic	Coding sequence variant, missense variant
rs137853144	T>A	Pathogenic	Coding sequence variant, stop gained
rs137853145	G>A,C,T	Pathogenic	Synonymous variant, coding sequence variant, missense variant, stop gained
rs137853926	G>A	Pathogenic	Coding sequence variant, stop gained
rs137853927	C>A	Pathogenic	Coding sequence variant, missense variant
rs137853928	AC>-	Pathogenic	Coding sequence variant, frameshift variant
rs137853929	CCGCCGCGCGGATTGGGCGGCGG>-	Pathogenic	Coding sequence variant, frameshift variant
rs137853930	G>A	Pathogenic	Coding sequence variant, missense variant
rs137853931	G>-	Pathogenic	Coding sequence variant, frameshift variant
rs137853932	C>T	Pathogenic	Splice donor variant
rs137853933	C>A,G,T	Pathogenic	Coding sequence variant, missense variant
rs146027258	C>T	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs367543004	GTCCACCA>-	Pathogenic	Coding sequence variant, frameshift variant
rs748847434	C>G,T	Pathogenic	Intron variant
rs761746361	->T	Pathogenic	Coding sequence variant, frameshift variant
rs768727082	->G	Pathogenic	Coding sequence variant, frameshift variant
rs886041972	G>A	Pathogenic	Coding sequence variant, stop gained
rs1555758035	->C	Pathogenic	Frameshift variant, coding sequence variant
rs1600650861	->C	Pathogenic	Frameshift variant, coding sequence variant
rs1600651228	G>-	Pathogenic	Frameshift variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019983	hsa-miR-375	Microarray	20215506
MIRT023159	hsa-miR-124-3p	Microarray	18668037
MIRT030308	hsa-miR-26b-5p	Microarray	19088304
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT610083	hsa-miR-8485	HITS-CLIP	23824327
MIRT610082	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610081	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610080	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT610079	hsa-miR-7155-5p	HITS-CLIP	23824327
MIRT610078	hsa-miR-342-5p	HITS-CLIP	23824327
MIRT610077	hsa-miR-4664-5p	HITS-CLIP	23824327
MIRT610076	hsa-miR-4651	HITS-CLIP	23824327
MIRT610075	hsa-miR-608	HITS-CLIP	23824327
MIRT610074	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT610073	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT610072	hsa-miR-6737-5p	HITS-CLIP	23824327
MIRT610071	hsa-miR-6812-5p	HITS-CLIP	23824327
MIRT610070	hsa-miR-6819-5p	HITS-CLIP	23824327
MIRT910274	hsa-miR-1207-5p	CLIP-seq
MIRT910275	hsa-miR-1225-3p	CLIP-seq
MIRT910276	hsa-miR-1233	CLIP-seq
MIRT910277	hsa-miR-1321	CLIP-seq
MIRT910278	hsa-miR-4270	CLIP-seq
MIRT910279	hsa-miR-4441	CLIP-seq
MIRT910280	hsa-miR-4728-5p	CLIP-seq
MIRT910281	hsa-miR-4736	CLIP-seq
MIRT910282	hsa-miR-4739	CLIP-seq
MIRT910283	hsa-miR-4756-5p	CLIP-seq
MIRT910284	hsa-miR-4763-3p	CLIP-seq
MIRT910274	hsa-miR-1207-5p	CLIP-seq
MIRT910277	hsa-miR-1321	CLIP-seq
MIRT1969864	hsa-miR-329	CLIP-seq
MIRT910278	hsa-miR-4270	CLIP-seq
MIRT910279	hsa-miR-4441	CLIP-seq
MIRT910280	hsa-miR-4728-5p	CLIP-seq
MIRT910281	hsa-miR-4736	CLIP-seq
MIRT910282	hsa-miR-4739	CLIP-seq
MIRT910283	hsa-miR-4756-5p	CLIP-seq
MIRT910284	hsa-miR-4763-3p	CLIP-seq
MIRT1969864	hsa-miR-329	CLIP-seq
MIRT2205858	hsa-miR-377	CLIP-seq
MIRT1969864	hsa-miR-329	CLIP-seq
MIRT2205858	hsa-miR-377	CLIP-seq
MIRT2436473	hsa-miR-4757-5p	CLIP-seq
MIRT2447626	hsa-miR-1229	CLIP-seq
MIRT2447627	hsa-miR-3127-3p	CLIP-seq
MIRT2447628	hsa-miR-361-3p	CLIP-seq
MIRT1969864	hsa-miR-329	CLIP-seq
MIRT2205858	hsa-miR-377	CLIP-seq
MIRT1969864	hsa-miR-329	CLIP-seq
MIRT2205858	hsa-miR-377	CLIP-seq
MIRT2678663	hsa-miR-4633-3p	CLIP-seq
MIRT2436473	hsa-miR-4757-5p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
PLAG1	Activation	14712223

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001657	Process	Ureteric bud development	IEA
GO:0004896	Function	Cytokine receptor activity	IBA
GO:0005125	Function	Cytokine activity	IDA	10966616
GO:0005127	Function	Ciliary neurotrophic factor receptor binding	IDA	10966616
GO:0005515	Function	Protein binding	IPI	10966616, 19933857, 26858303
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	TAS	9686600
GO:0005829	Component	Cytosol	TAS
GO:0008284	Process	Positive regulation of cell population proliferation	IBA
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	10966616
GO:0009897	Component	External side of plasma membrane	IBA
GO:0019221	Process	Cytokine-mediated signaling pathway	IBA
GO:0019955	Function	Cytokine binding	IBA
GO:0019955	Function	Cytokine binding	IPI	15034937
GO:0043235	Component	Receptor complex	IBA
GO:0043524	Process	Negative regulation of neuron apoptotic process	IBA
GO:0043524	Process	Negative regulation of neuron apoptotic process	IDA	10966616
GO:0043524	Process	Negative regulation of neuron apoptotic process	IEA
GO:0097058	Component	CRLF-CLCF1 complex	IBA
GO:0097058	Component	CRLF-CLCF1 complex	IDA	10966616
GO:0097058	Component	CRLF-CLCF1 complex	IEA
GO:0097696	Process	Cell surface receptor signaling pathway via STAT	IDA	10966616
GO:0097696	Process	Cell surface receptor signaling pathway via STAT	IEA
GO:2000672	Process	Negative regulation of motor neuron apoptotic process	IEA

Other IDs

• MIM: 604237
• HGNC: 2364
• e!Ensembl: ENSG00000006016

Protein

• UniProt ID: O75462
• Protein name: Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5)
• Protein function: In complex with CLCF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). May also play a regulatory role in the immune system.
• PDB: 8D7H
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF09067	EpoR_lig-bind	131 → 228	Erythropoietin receptor, ligand binding	Domain
  PF00041	fn3	236 → 317	Fibronectin type III domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung. {ECO:0000269|PubMed:9686600}.
• Sequence:

  MPAGRRGPAAQSARRPPPLLPLLLLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATC
  SVHGDPPGATAEGLYWTLNGRRLPPELSRVLNASTLALALANLNGSRQRSGDNLVCHARD
  GSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWYGQ
  DNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPD
  VHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAG
  LKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGACEPRGGEPSS
  GPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGP
  AR

• Sequence length: 422

Pathways

Reactome:

IL-6-type cytokine receptor ligand interactions
Interleukin-27 signaling

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Cold-induced sweating syndrome	Likely pathogenic; Pathogenic	rs2145339928, rs2513397402, rs2513397377, rs137853929	RCV002271797 RCV002281810 RCV003988489 RCV003323930	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Cold-induced sweating syndrome 1	Pathogenic; Likely pathogenic	rs1199919814, rs2513391100, rs768727082, rs1976145478, rs761746361, rs137853143, rs137853144, rs2145329741, rs137853145, rs137853928, rs745392621, rs367543004, rs137853929, rs137853932, rs1555758035, rs1600650861, rs137853933, rs1976175724	RCV002052184 RCV002287528 RCV002285031 RCV002262181 RCV000006061 RCV000006062 RCV000006065 RCV000006066 RCV000006067 RCV000195773 RCV000210224 RCV003313730 RCV000020063 RCV001780581 RCV003988099 RCV001283834 RCV001007859 RCV001268950 RCV001268951	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Cone-rod dystrophy 12	Likely pathogenic; Pathogenic	rs137853932	RCV003236599	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Crisponi/Cold-induced sweating syndrome	Pathogenic	rs1600651228	RCV000790409	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
CRLF1-related disorder	Pathogenic	rs768727082	RCV004758669	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CRISPONI SYNDROME	—	CTD, Disgenet, Orphanet CTD, Disgenet, Orphanet CTD, Disgenet, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CRISPONI/COLD-INDUCED SWEATING SYNDROME 1	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL ULCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, SPINE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acoustic Neuroma	Acoustic Neuroma	BEFREE	28947096, 29561382, 30095338		★☆☆☆☆ Found in Text Mining only
Acquired Kyphoscoliosis	Acquired Kyphoscoliosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Anhidrosis	Anhidrosis	BEFREE	26804344		★☆☆☆☆ Found in Text Mining only
Arthritis Juvenile	Juvenile arthritis	Pubtator	36167601	Stimulate	★☆☆☆☆ Found in Text Mining only
Bohring syndrome	Bohring-Opitz syndrome	BEFREE	30300710		★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	29773567		★☆☆☆☆ Found in Text Mining only
Byzanthine arch palate	High palate	HPO_DG			★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	27378695	Associate	★☆☆☆☆ Found in Text Mining only
Cartilage Diseases	Cartilage disease	Pubtator	17935617	Associate	★☆☆☆☆ Found in Text Mining only
Cold-induced sweating syndrome	Cold-Induced Sweating Syndrome	Orphanet			★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
COLD-INDUCED SWEATING SYNDROME 1	Cold-Induced Sweating Syndrome	ORPHANET_DG	12509788, 17436251		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
COLD-INDUCED SWEATING SYNDROME 1	Cold-Induced Sweating Syndrome	UNIPROT_DG	12509788, 16952376, 17436251, 17436252, 21326283, 23026229, 24488861		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
COLD-INDUCED SWEATING SYNDROME 1	Cold-Induced Sweating Syndrome	GENOMICS_ENGLAND_DG	12509788		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
COLD-INDUCED SWEATING SYNDROME 1	Cold-Induced Sweating Syndrome	BEFREE	24488861, 24613578		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
COLD-INDUCED SWEATING SYNDROME 1	Cold-Induced Sweating Syndrome	CLINVAR_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
COLD-INDUCED SWEATING SYNDROME 1	Cold-Induced Sweating Syndrome	CTD_human_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
COLD-INDUCED SWEATING SYNDROME 2	Cold-Induced Sweating Syndrome	CTD_human_DG			★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	28437455		★☆☆☆☆ Found in Text Mining only
Congenital Camptodactyly	Congenital Camptodactyly	HPO_DG			★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	9810318		★☆☆☆☆ Found in Text Mining only
Congenital clubfoot	Congenital Clubfoot	HPO_DG			★☆☆☆☆ Found in Text Mining only
Congenital kyphoscoliosis	Congenital kyphoscoliosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Convergence Insufficiency	Convergence Insufficiency	BEFREE	27464572, 27464574, 31651593		★☆☆☆☆ Found in Text Mining only
Crisponi syndrome	Crisponi Syndrome	ORPHANET_DG	12509788, 17436251, 17436252		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Crisponi syndrome	Crisponi Syndrome	BEFREE	16782820, 17436251, 17436252, 20186812, 20400119, 21326283, 23181498, 24008591, 24488861, 24613578, 27392078, 30142437, 30300710		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Crisponi syndrome	Crisponi syndrome	Pubtator	17436251, 17436252, 27392078	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Crisponi syndrome	Crisponi Syndrome	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Crisponi syndrome	Crisponi Syndrome	CTD_human_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Crisponi syndrome	Crisponi Syndrome	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Degenerative polyarthritis	Arthritis	BEFREE	19921088, 30298554		★☆☆☆☆ Found in Text Mining only
Dermatofibrosis lenticularis disseminata	Dermatofibrosis Lenticularis Disseminata	BEFREE	29074562, 30300710		★☆☆☆☆ Found in Text Mining only
Dysmorphic features	Dysmorphic Features	BEFREE	24488861		★☆☆☆☆ Found in Text Mining only
Esophageal Achalasia	Achalasia	BEFREE	27976805		★☆☆☆☆ Found in Text Mining only
Esophageal Achalasia	Achalasia	ORPHANET_DG	27976805		★☆☆☆☆ Found in Text Mining only
Facial paralysis	Facial paralysis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Flexion contracture - elbow	Elbow flexion contracture	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hematologic Neoplasms	Hematologic neoplasm	Pubtator	25679997	Associate	★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	30882592		★☆☆☆☆ Found in Text Mining only
Hypohidrosis	Hypohidrosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Idiopathic achalasia of esophagus	Idiopathic achalasia	ORPHANET_DG	27976805		★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	22429962		★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	HPO_DG			★☆☆☆☆ Found in Text Mining only
Keratitis	Keratitis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Meniere Disease	Meniere Disease	BEFREE	29168026		★☆☆☆☆ Found in Text Mining only
Mesothelioma Malignant	Mesothelioma	Pubtator	37047661	Associate	★☆☆☆☆ Found in Text Mining only
Micrognathism	Micrognathism	HPO_DG			★☆☆☆☆ Found in Text Mining only
Microstomia	Microstomia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Moyamoya Disease	Moyamoya Disease	BEFREE	30315975		★☆☆☆☆ Found in Text Mining only
Moyamoya disease 1	Moyamoya disease	BEFREE	30315975		★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	25679997		★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	25679997	Stimulate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29515111, 30339649, 31624121		★☆☆☆☆ Found in Text Mining only
Neoplasms, Intracranial	Intracranial Neoplasm	BEFREE	29773567		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	23818941		★☆☆☆☆ Found in Text Mining only
Oral Ulcer	Oral Ulcer	GWASCAT_DG	30837455		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	30298554	Associate	★☆☆☆☆ Found in Text Mining only
Papillary thyroid carcinoma	Papillary thyroid carcinoma	BEFREE	29515111		★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	22429962		★☆☆☆☆ Found in Text Mining only
Retinitis Pigmentosa	Retinitis Pigmentosa	BEFREE	27392078		★☆☆☆☆ Found in Text Mining only
Scoliosis, unspecified	Scoliosis	BEFREE	27392078		★☆☆☆☆ Found in Text Mining only
Scoliosis, unspecified	Scoliosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Spinal stenosis of lumbar region	Spinal Stenosis Of Lumbar Region	BEFREE	29329787		★☆☆☆☆ Found in Text Mining only
Strabismus	Strabismus	BEFREE	27464572		★☆☆☆☆ Found in Text Mining only
STUVE-WIEDEMANN SYNDROME	Stuve-Wiedemann syndrome	BEFREE	17436252		★☆☆☆☆ Found in Text Mining only
Trigeminal Neuralgia	Trigeminal neuralgia	BEFREE	29388798, 30139749		★☆☆☆☆ Found in Text Mining only
Trismus	Trismus	HPO_DG			★☆☆☆☆ Found in Text Mining only