CCPG1 (cell cycle progression 1)

Gene

• Entrez ID: 9236
• Gene name: Cell cycle progression 1
• Gene symbol: CCPG1
• Synonyms (NCBI Gene): CPR8
• Chromosome: 15
• Chromosome location: 15q21.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017366	hsa-miR-335-5p	Microarray	18185580
MIRT028465	hsa-miR-30a-5p	Proteomics	18668040
MIRT031530	hsa-miR-16-5p	Proteomics	18668040
MIRT442160	hsa-miR-4632-3p	PAR-CLIP	22291592
MIRT442160	hsa-miR-4632-3p	PAR-CLIP	23708386
MIRT459095	hsa-miR-4282	PAR-CLIP	23592263
MIRT459094	hsa-miR-759	PAR-CLIP	23592263
MIRT459093	hsa-miR-345-5p	PAR-CLIP	23592263
MIRT459092	hsa-miR-617	PAR-CLIP	23592263
MIRT459091	hsa-miR-6505-3p	PAR-CLIP	23592263
MIRT459090	hsa-miR-6847-3p	PAR-CLIP	23592263
MIRT459089	hsa-miR-4256	PAR-CLIP	23592263
MIRT459088	hsa-miR-1178-3p	PAR-CLIP	23592263
MIRT459087	hsa-miR-5010-3p	PAR-CLIP	23592263
MIRT442160	hsa-miR-4632-3p	PAR-CLIP	22100165
MIRT442160	hsa-miR-4632-3p	PAR-CLIP	22291592
MIRT442160	hsa-miR-4632-3p	PAR-CLIP	23708386
MIRT459095	hsa-miR-4282	PAR-CLIP	23592263
MIRT459094	hsa-miR-759	PAR-CLIP	23592263
MIRT459093	hsa-miR-345-5p	PAR-CLIP	23592263
MIRT459092	hsa-miR-617	PAR-CLIP	23592263
MIRT459091	hsa-miR-6505-3p	PAR-CLIP	23592263
MIRT459090	hsa-miR-6847-3p	PAR-CLIP	23592263
MIRT459089	hsa-miR-4256	PAR-CLIP	23592263
MIRT459088	hsa-miR-1178-3p	PAR-CLIP	23592263
MIRT459087	hsa-miR-5010-3p	PAR-CLIP	23592263
MIRT442160	hsa-miR-4632-3p	PAR-CLIP	22100165
MIRT873142	hsa-miR-1272	CLIP-seq
MIRT873143	hsa-miR-2053	CLIP-seq
MIRT873144	hsa-miR-3163	CLIP-seq
MIRT873145	hsa-miR-340	CLIP-seq
MIRT873146	hsa-miR-3662	CLIP-seq
MIRT873147	hsa-miR-548u	CLIP-seq
MIRT873148	hsa-miR-569	CLIP-seq
MIRT873149	hsa-miR-1307	CLIP-seq
MIRT873150	hsa-miR-139-5p	CLIP-seq
MIRT873151	hsa-miR-18a	CLIP-seq
MIRT873152	hsa-miR-18b	CLIP-seq
MIRT873153	hsa-miR-193a-3p	CLIP-seq
MIRT873154	hsa-miR-193b	CLIP-seq
MIRT873155	hsa-miR-3128	CLIP-seq
MIRT873156	hsa-miR-3613-3p	CLIP-seq
MIRT873157	hsa-miR-4261	CLIP-seq
MIRT873158	hsa-miR-4294	CLIP-seq
MIRT873159	hsa-miR-4470	CLIP-seq
MIRT873160	hsa-miR-4638-5p	CLIP-seq
MIRT873161	hsa-miR-4735-3p	CLIP-seq
MIRT873162	hsa-miR-548a-3p	CLIP-seq
MIRT873163	hsa-miR-548e	CLIP-seq
MIRT873164	hsa-miR-548f	CLIP-seq
MIRT873165	hsa-miR-582-5p	CLIP-seq
MIRT873166	hsa-miR-892b	CLIP-seq
MIRT873167	hsa-miR-4455	CLIP-seq
MIRT873168	hsa-miR-564	CLIP-seq
MIRT1959071	hsa-miR-145	CLIP-seq
MIRT1959072	hsa-miR-1825	CLIP-seq
MIRT1959073	hsa-miR-199a-5p	CLIP-seq
MIRT1959074	hsa-miR-199b-5p	CLIP-seq
MIRT1959075	hsa-miR-3180-5p	CLIP-seq
MIRT873143	hsa-miR-2053	CLIP-seq
MIRT2196015	hsa-miR-4422	CLIP-seq
MIRT2446532	hsa-miR-3647-3p	CLIP-seq
MIRT2446533	hsa-miR-3675-3p	CLIP-seq
MIRT873167	hsa-miR-4455	CLIP-seq
MIRT2446534	hsa-miR-4517	CLIP-seq
MIRT2446535	hsa-miR-4684-5p	CLIP-seq
MIRT2446536	hsa-miR-548c-3p	CLIP-seq
MIRT2499061	hsa-miR-1254	CLIP-seq
MIRT2499062	hsa-miR-1267	CLIP-seq
MIRT873150	hsa-miR-139-5p	CLIP-seq
MIRT1959071	hsa-miR-145	CLIP-seq
MIRT1959072	hsa-miR-1825	CLIP-seq
MIRT1959073	hsa-miR-199a-5p	CLIP-seq
MIRT1959074	hsa-miR-199b-5p	CLIP-seq
MIRT2499063	hsa-miR-300	CLIP-seq
MIRT2499064	hsa-miR-3116	CLIP-seq
MIRT1959075	hsa-miR-3180-5p	CLIP-seq
MIRT2499065	hsa-miR-330-3p	CLIP-seq
MIRT873156	hsa-miR-3613-3p	CLIP-seq
MIRT2499066	hsa-miR-3617	CLIP-seq
MIRT2499067	hsa-miR-3665	CLIP-seq
MIRT2499068	hsa-miR-381	CLIP-seq
MIRT2499069	hsa-miR-4272	CLIP-seq
MIRT2196015	hsa-miR-4422	CLIP-seq
MIRT2499070	hsa-miR-4528	CLIP-seq
MIRT2499071	hsa-miR-4666-3p	CLIP-seq
MIRT2499072	hsa-miR-4684-3p	CLIP-seq
MIRT2499073	hsa-miR-4700-3p	CLIP-seq
MIRT2499074	hsa-miR-4735-5p	CLIP-seq
MIRT2499075	hsa-miR-4753-3p	CLIP-seq
MIRT2499076	hsa-miR-4766-5p	CLIP-seq
MIRT2499077	hsa-miR-4768-5p	CLIP-seq
MIRT2499078	hsa-miR-4789-5p	CLIP-seq
MIRT2499079	hsa-miR-488	CLIP-seq
MIRT2499080	hsa-miR-513a-3p	CLIP-seq
MIRT2499081	hsa-miR-516a-3p	CLIP-seq
MIRT2499082	hsa-miR-520d-5p	CLIP-seq
MIRT2499083	hsa-miR-524-5p	CLIP-seq
MIRT873162	hsa-miR-548a-3p	CLIP-seq
MIRT873163	hsa-miR-548e	CLIP-seq
MIRT873164	hsa-miR-548f	CLIP-seq
MIRT873165	hsa-miR-582-5p	CLIP-seq
MIRT2499084	hsa-miR-600	CLIP-seq
MIRT2499085	hsa-miR-641	CLIP-seq
MIRT2499086	hsa-miR-657	CLIP-seq
MIRT2499087	hsa-miR-661	CLIP-seq
MIRT2499088	hsa-miR-95	CLIP-seq
MIRT2677554	hsa-miR-1238	CLIP-seq
MIRT2499061	hsa-miR-1254	CLIP-seq
MIRT2677555	hsa-miR-1273f	CLIP-seq
MIRT2677556	hsa-miR-1290	CLIP-seq
MIRT2677557	hsa-miR-1305	CLIP-seq
MIRT2677558	hsa-miR-135a	CLIP-seq
MIRT2677559	hsa-miR-135b	CLIP-seq
MIRT873150	hsa-miR-139-5p	CLIP-seq
MIRT2677560	hsa-miR-143	CLIP-seq
MIRT1959071	hsa-miR-145	CLIP-seq
MIRT1959072	hsa-miR-1825	CLIP-seq
MIRT1959073	hsa-miR-199a-5p	CLIP-seq
MIRT1959074	hsa-miR-199b-5p	CLIP-seq
MIRT2677561	hsa-miR-205	CLIP-seq
MIRT2499063	hsa-miR-300	CLIP-seq
MIRT2677562	hsa-miR-30a	CLIP-seq
MIRT2677563	hsa-miR-30b	CLIP-seq
MIRT2677564	hsa-miR-30c	CLIP-seq
MIRT2677565	hsa-miR-30d	CLIP-seq
MIRT2677566	hsa-miR-30e	CLIP-seq
MIRT2499064	hsa-miR-3116	CLIP-seq
MIRT2677567	hsa-miR-3119	CLIP-seq
MIRT2677568	hsa-miR-3124-3p	CLIP-seq
MIRT2677569	hsa-miR-3129-3p	CLIP-seq
MIRT2677570	hsa-miR-3140-3p	CLIP-seq
MIRT2677571	hsa-miR-3162-3p	CLIP-seq
MIRT2677572	hsa-miR-3167	CLIP-seq
MIRT1959075	hsa-miR-3180-5p	CLIP-seq
MIRT2677573	hsa-miR-3182	CLIP-seq
MIRT2499065	hsa-miR-330-3p	CLIP-seq
MIRT2677574	hsa-miR-345	CLIP-seq
MIRT2677575	hsa-miR-3611	CLIP-seq
MIRT873156	hsa-miR-3613-3p	CLIP-seq
MIRT2677576	hsa-miR-3614-3p	CLIP-seq
MIRT2446532	hsa-miR-3647-3p	CLIP-seq
MIRT2499067	hsa-miR-3665	CLIP-seq
MIRT2677577	hsa-miR-3670	CLIP-seq
MIRT2677578	hsa-miR-3671	CLIP-seq
MIRT2446533	hsa-miR-3675-3p	CLIP-seq
MIRT2677579	hsa-miR-3682-5p	CLIP-seq
MIRT2677580	hsa-miR-371-5p	CLIP-seq
MIRT2677581	hsa-miR-371b-5p	CLIP-seq
MIRT2499068	hsa-miR-381	CLIP-seq
MIRT2677582	hsa-miR-411	CLIP-seq
MIRT2499069	hsa-miR-4272	CLIP-seq
MIRT2677583	hsa-miR-4279	CLIP-seq
MIRT2677584	hsa-miR-4286	CLIP-seq
MIRT2677585	hsa-miR-4297	CLIP-seq
MIRT2677586	hsa-miR-4307	CLIP-seq
MIRT2677587	hsa-miR-4421	CLIP-seq
MIRT2196015	hsa-miR-4422	CLIP-seq
MIRT2677588	hsa-miR-4457	CLIP-seq
MIRT2446534	hsa-miR-4517	CLIP-seq
MIRT2677589	hsa-miR-451b	CLIP-seq
MIRT2499070	hsa-miR-4528	CLIP-seq
MIRT2499071	hsa-miR-4666-3p	CLIP-seq
MIRT2446535	hsa-miR-4684-5p	CLIP-seq
MIRT2499073	hsa-miR-4700-3p	CLIP-seq
MIRT2677590	hsa-miR-4708-5p	CLIP-seq
MIRT2677591	hsa-miR-4729	CLIP-seq
MIRT2499074	hsa-miR-4735-5p	CLIP-seq
MIRT2499075	hsa-miR-4753-3p	CLIP-seq
MIRT2677592	hsa-miR-4761-5p	CLIP-seq
MIRT2677593	hsa-miR-4764-3p	CLIP-seq
MIRT2499077	hsa-miR-4768-5p	CLIP-seq
MIRT2677594	hsa-miR-4770	CLIP-seq
MIRT2499078	hsa-miR-4789-5p	CLIP-seq
MIRT2677595	hsa-miR-483-3p	CLIP-seq
MIRT2677596	hsa-miR-498	CLIP-seq
MIRT2499080	hsa-miR-513a-3p	CLIP-seq
MIRT2677597	hsa-miR-513b	CLIP-seq
MIRT2499081	hsa-miR-516a-3p	CLIP-seq
MIRT2499082	hsa-miR-520d-5p	CLIP-seq
MIRT2499083	hsa-miR-524-5p	CLIP-seq
MIRT873162	hsa-miR-548a-3p	CLIP-seq
MIRT2446536	hsa-miR-548c-3p	CLIP-seq
MIRT873163	hsa-miR-548e	CLIP-seq
MIRT873164	hsa-miR-548f	CLIP-seq
MIRT2677598	hsa-miR-556-5p	CLIP-seq
MIRT873165	hsa-miR-582-5p	CLIP-seq
MIRT2677599	hsa-miR-590-3p	CLIP-seq
MIRT2499084	hsa-miR-600	CLIP-seq
MIRT2677600	hsa-miR-642b	CLIP-seq
MIRT2499086	hsa-miR-657	CLIP-seq
MIRT2499087	hsa-miR-661	CLIP-seq
MIRT2677601	hsa-miR-876-5p	CLIP-seq
MIRT2499088	hsa-miR-95	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25126726
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	20957177
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0045787	Process	Positive regulation of cell cycle	IMP	20957177
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA

Other IDs

• MIM: 611326
• HGNC: 24227
• e!Ensembl: ENSG00000260916

Protein

• UniProt ID: Q9ULG6
• Protein name: Cell cycle progression protein 1 (Cell cycle progression restoration protein 8)
• Protein function: Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does
• PDB: 7D0E
• Sequence:

  MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGES
  SQNGTVLMEETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQ
  EVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRA
  RKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQI
  QKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWTLTEAEKMSFETQK
  TNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEE
  EKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTE
  KKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNK
  SKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTT
  KNIFDEKGNKRFGATKEAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHF
  KEFRKNTNSKKCSPGHDCRENSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQII
  QRYMLKELDTFCHWNELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDG
  VFEKLDEYIYRHFFGHTFSPPYGPRSVYIKPCHYSSL

• Sequence length: 757

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 80	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37540697	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	36047377	Associate	★☆☆☆☆ Found in Text Mining only