C1orf105 (chromosome 1 open reading frame 105)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 92346
Gene name Chromosome 1 open reading frame 105
Gene symbol C1orf105
Synonyms (NCBI Gene)
-
Chromosome 1
Chromosome location 1q24.3
miRNA miRNA information provided by mirtarbase database.
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (2)
miRTarBase ID miRNA Experiments Reference
MIRT1948842 hsa-miR-3689a-3p CLIP-seq
MIRT1948843 hsa-miR-3689c CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (1)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 28514442, 32296183, 33961781
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95561
Protein name Uncharacterized protein C1orf105
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15081 DUF4548 17 → 182 Domain of unknown function (DUF4548) Family
Sequence
Sequence length 183
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (4)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
GLOBAL DEVELOPMENTAL DELAY — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 16 — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYDROPS FETALIS, NON-IMMUNE — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TREATMENT-RESISTANT HYPERTENSION — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (6)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Atrial Fibrillation Atrial fibrillation Pubtator 32682418, 36295481 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Coronary Artery Disease Coronary artery disease Pubtator 36222281 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 16 Glycosylphosphatidylinositol deficiency CLINVAR_DG 27694521
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Heart Failure Heart failure Pubtator 36295481 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Hydrops Fetalis, Non-Immune Hydrops Fetalis CLINVAR_DG 26036949
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Intellectual Disability Mental retardation BEFREE 30079626
★★★★★
★☆☆☆☆
Found in Text Mining only