Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	9182
Gene name	Ras association domain family member 9
Gene symbol	RASSF9
Synonyms (NCBI Gene)	P-CIP1PAMCIPCIP1
Chromosome	12
Chromosome location	12q21.31
Summary	The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways. [provided by

Show/Hide all (90)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027560	hsa-miR-98-5p	Microarray	19088304
MIRT029162	hsa-miR-26b-5p	Microarray	19088304
MIRT619435	hsa-miR-8485	HITS-CLIP	23313552
MIRT619434	hsa-miR-1283	HITS-CLIP	23313552
MIRT619433	hsa-miR-187-5p	HITS-CLIP	23313552
MIRT674907	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT674906	hsa-miR-4457	HITS-CLIP	23824327
MIRT674905	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT674904	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT674903	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT674902	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT674901	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT674900	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT674899	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT674898	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT674897	hsa-miR-363-5p	HITS-CLIP	23824327
MIRT674896	hsa-miR-6745	HITS-CLIP	23824327
MIRT674895	hsa-miR-3165	HITS-CLIP	23824327
MIRT674894	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT674893	hsa-miR-7977	HITS-CLIP	23824327
MIRT674892	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT674891	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT674890	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT674889	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT674888	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT674887	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT674886	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT674885	hsa-miR-3689c	HITS-CLIP	23824327
MIRT674884	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT674883	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT674882	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT674881	hsa-miR-3122	HITS-CLIP	23824327
MIRT674880	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT674879	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT674878	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT634365	hsa-miR-7112-5p	HITS-CLIP	23824327
MIRT634364	hsa-miR-564	HITS-CLIP	23824327
MIRT634363	hsa-miR-4284	HITS-CLIP	23824327
MIRT634362	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT631577	hsa-miR-4282	HITS-CLIP	23824327
MIRT619434	hsa-miR-1283	HITS-CLIP	23824327
MIRT631576	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT619433	hsa-miR-187-5p	HITS-CLIP	23824327
MIRT619435	hsa-miR-8485	HITS-CLIP	23824327
MIRT619434	hsa-miR-1283	HITS-CLIP	23824327
MIRT619433	hsa-miR-187-5p	HITS-CLIP	23824327
MIRT619435	hsa-miR-8485	HITS-CLIP	23313552
MIRT619434	hsa-miR-1283	HITS-CLIP	23313552
MIRT619433	hsa-miR-187-5p	HITS-CLIP	23313552
MIRT674907	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT674906	hsa-miR-4457	HITS-CLIP	23824327
MIRT674905	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT674904	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT674903	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT674902	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT674901	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT674900	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT674899	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT674898	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT674897	hsa-miR-363-5p	HITS-CLIP	23824327
MIRT674896	hsa-miR-6745	HITS-CLIP	23824327
MIRT674895	hsa-miR-3165	HITS-CLIP	23824327
MIRT674894	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT674893	hsa-miR-7977	HITS-CLIP	23824327
MIRT674892	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT674891	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT674890	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT674889	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT674888	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT674887	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT674886	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT674885	hsa-miR-3689c	HITS-CLIP	23824327
MIRT674884	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT674883	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT674882	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT674881	hsa-miR-3122	HITS-CLIP	23824327
MIRT674880	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT674879	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT674878	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT634365	hsa-miR-7112-5p	HITS-CLIP	23824327
MIRT634364	hsa-miR-564	HITS-CLIP	23824327
MIRT634363	hsa-miR-4284	HITS-CLIP	23824327
MIRT634362	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT631577	hsa-miR-4282	HITS-CLIP	23824327
MIRT619434	hsa-miR-1283	HITS-CLIP	23824327
MIRT631576	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT619433	hsa-miR-187-5p	HITS-CLIP	23824327
MIRT619435	hsa-miR-8485	HITS-CLIP	23824327
MIRT619434	hsa-miR-1283	HITS-CLIP	23824327
MIRT619433	hsa-miR-187-5p	HITS-CLIP	23824327

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	9837933
GO:0005768	Component	Endosome	IDA	9837933
GO:0005768	Component	Endosome	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	9837933
GO:0005829	Component	Cytosol	IEA
GO:0006605	Process	Protein targeting	NAS	9837933
GO:0007165	Process	Signal transduction	IEA
GO:0012510	Component	Trans-Golgi network transport vesicle membrane	IBA
GO:0012510	Component	Trans-Golgi network transport vesicle membrane	IDA	9837933
GO:0012510	Component	Trans-Golgi network transport vesicle membrane	IEA
GO:0016197	Process	Endosomal transport	NAS	9837933
GO:0046907	Process	Intracellular transport	IBA
GO:0055037	Component	Recycling endosome	IBA
GO:0070062	Component	Extracellular exosome	HDA	18570454

MIM	HGNC	e!Ensembl
610383	15739	ENSG00000198774

O75901

Protein name

Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor)

Protein function

May play a role in regulating vesicuar trafficking in cells.

Family and domains

Sequence

MAPFGRNLLKTRHKNRSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEH
EATFGEKRFLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAF
LPVPLWRTAEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDR
DNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSF
SEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINE
DAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELL
AKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTDSDTGISSNHS
QDSETTVGDVVLLST

Sequence length

435

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ASTROCYTOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEWY BODY DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Premature coronary artery atherosclerosis	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Carcinoma	Breast Carcinoma	BEFREE	30132526	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	30132526	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	31768130	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	31768130	★★★★★ ★☆☆☆☆ Found in Text Mining only

RASSF9 (Ras association domain family member 9)