CHMP7 (charged multivesicular body protein 7)

Gene

• Entrez ID: 91782
• Gene name: Charged multivesicular body protein 7
• Gene symbol: CHMP7
• Synonyms (NCBI Gene): -
• Chromosome: 8
• Chromosome location: 8p21.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT030249	hsa-miR-26b-5p	Microarray	19088304
MIRT046411	hsa-miR-15b-5p	CLASH	23622248
MIRT042391	hsa-miR-484	CLASH	23622248
MIRT037936	hsa-miR-505-5p	CLASH	23622248
MIRT890872	hsa-miR-1179	CLIP-seq
MIRT890873	hsa-miR-1202	CLIP-seq
MIRT890874	hsa-miR-1236	CLIP-seq
MIRT890875	hsa-miR-1245	CLIP-seq
MIRT890876	hsa-miR-1250	CLIP-seq
MIRT890877	hsa-miR-1302	CLIP-seq
MIRT890878	hsa-miR-149	CLIP-seq
MIRT890879	hsa-miR-190	CLIP-seq
MIRT890880	hsa-miR-190b	CLIP-seq
MIRT890881	hsa-miR-214	CLIP-seq
MIRT890882	hsa-miR-219-5p	CLIP-seq
MIRT890883	hsa-miR-3145-5p	CLIP-seq
MIRT890884	hsa-miR-3152-5p	CLIP-seq
MIRT890885	hsa-miR-329	CLIP-seq
MIRT890886	hsa-miR-3619-5p	CLIP-seq
MIRT890887	hsa-miR-362-3p	CLIP-seq
MIRT890888	hsa-miR-3646	CLIP-seq
MIRT890889	hsa-miR-3662	CLIP-seq
MIRT890890	hsa-miR-3675-5p	CLIP-seq
MIRT890891	hsa-miR-3919	CLIP-seq
MIRT890892	hsa-miR-3924	CLIP-seq
MIRT890893	hsa-miR-3940-3p	CLIP-seq
MIRT890894	hsa-miR-3941	CLIP-seq
MIRT890895	hsa-miR-3972	CLIP-seq
MIRT890896	hsa-miR-412	CLIP-seq
MIRT890897	hsa-miR-4269	CLIP-seq
MIRT890898	hsa-miR-4298	CLIP-seq
MIRT890899	hsa-miR-4317	CLIP-seq
MIRT890900	hsa-miR-4445	CLIP-seq
MIRT890901	hsa-miR-4514	CLIP-seq
MIRT890902	hsa-miR-4645-5p	CLIP-seq
MIRT890903	hsa-miR-4648	CLIP-seq
MIRT890904	hsa-miR-4662a-3p	CLIP-seq
MIRT890905	hsa-miR-4673	CLIP-seq
MIRT890906	hsa-miR-4692	CLIP-seq
MIRT890907	hsa-miR-4698	CLIP-seq
MIRT890908	hsa-miR-4742-5p	CLIP-seq
MIRT890909	hsa-miR-4753-3p	CLIP-seq
MIRT890910	hsa-miR-4756-3p	CLIP-seq
MIRT890911	hsa-miR-4768-5p	CLIP-seq
MIRT890912	hsa-miR-4774-3p	CLIP-seq
MIRT890913	hsa-miR-4782-3p	CLIP-seq
MIRT890914	hsa-miR-4783-3p	CLIP-seq
MIRT890915	hsa-miR-494	CLIP-seq
MIRT890916	hsa-miR-508-3p	CLIP-seq
MIRT890917	hsa-miR-508-5p	CLIP-seq
MIRT890918	hsa-miR-578	CLIP-seq
MIRT890919	hsa-miR-603	CLIP-seq
MIRT890920	hsa-miR-7	CLIP-seq
MIRT890921	hsa-miR-761	CLIP-seq
MIRT1964054	hsa-miR-105	CLIP-seq
MIRT1964055	hsa-miR-1207-3p	CLIP-seq
MIRT890874	hsa-miR-1236	CLIP-seq
MIRT1964056	hsa-miR-1253	CLIP-seq
MIRT1964057	hsa-miR-1254	CLIP-seq
MIRT1964058	hsa-miR-1285	CLIP-seq
MIRT890877	hsa-miR-1302	CLIP-seq
MIRT1964059	hsa-miR-140-5p	CLIP-seq
MIRT1964060	hsa-miR-142-5p	CLIP-seq
MIRT1964061	hsa-miR-147	CLIP-seq
MIRT1964062	hsa-miR-1827	CLIP-seq
MIRT1964063	hsa-miR-2114	CLIP-seq
MIRT1964064	hsa-miR-2115	CLIP-seq
MIRT1964065	hsa-miR-218	CLIP-seq
MIRT1964066	hsa-miR-3116	CLIP-seq
MIRT1964067	hsa-miR-3163	CLIP-seq
MIRT1964068	hsa-miR-3173-3p	CLIP-seq
MIRT1964069	hsa-miR-3176	CLIP-seq
MIRT1964070	hsa-miR-3187-5p	CLIP-seq
MIRT1964071	hsa-miR-3192	CLIP-seq
MIRT1964072	hsa-miR-326	CLIP-seq
MIRT1964073	hsa-miR-330-5p	CLIP-seq
MIRT1964074	hsa-miR-340	CLIP-seq
MIRT1964075	hsa-miR-3612	CLIP-seq
MIRT1964076	hsa-miR-361-3p	CLIP-seq
MIRT1964077	hsa-miR-3614-5p	CLIP-seq
MIRT1964078	hsa-miR-3650	CLIP-seq
MIRT1964079	hsa-miR-3652	CLIP-seq
MIRT1964080	hsa-miR-3689d	CLIP-seq
MIRT1964081	hsa-miR-3691-3p	CLIP-seq
MIRT1964082	hsa-miR-3714	CLIP-seq
MIRT1964083	hsa-miR-378g	CLIP-seq
MIRT1964084	hsa-miR-3911	CLIP-seq
MIRT1964085	hsa-miR-3922-3p	CLIP-seq
MIRT1964086	hsa-miR-4251	CLIP-seq
MIRT1964087	hsa-miR-4254	CLIP-seq
MIRT1964088	hsa-miR-4268	CLIP-seq
MIRT1964089	hsa-miR-4279	CLIP-seq
MIRT1964090	hsa-miR-4286	CLIP-seq
MIRT890898	hsa-miR-4298	CLIP-seq
MIRT1964091	hsa-miR-4300	CLIP-seq
MIRT1964092	hsa-miR-4303	CLIP-seq
MIRT1964093	hsa-miR-4329	CLIP-seq
MIRT1964094	hsa-miR-4430	CLIP-seq
MIRT1964095	hsa-miR-4431	CLIP-seq
MIRT1964096	hsa-miR-4448	CLIP-seq
MIRT1964097	hsa-miR-4456	CLIP-seq
MIRT1964098	hsa-miR-4474-3p	CLIP-seq
MIRT1964099	hsa-miR-4486	CLIP-seq
MIRT1964100	hsa-miR-4505	CLIP-seq
MIRT1964101	hsa-miR-4522	CLIP-seq
MIRT1964102	hsa-miR-4531	CLIP-seq
MIRT1964103	hsa-miR-4640-5p	CLIP-seq
MIRT890903	hsa-miR-4648	CLIP-seq
MIRT1964104	hsa-miR-4660	CLIP-seq
MIRT1964105	hsa-miR-4693-3p	CLIP-seq
MIRT1964106	hsa-miR-4695-5p	CLIP-seq
MIRT1964107	hsa-miR-4726-5p	CLIP-seq
MIRT1964108	hsa-miR-4736	CLIP-seq
MIRT1964109	hsa-miR-4779	CLIP-seq
MIRT1964110	hsa-miR-577	CLIP-seq
MIRT890918	hsa-miR-578	CLIP-seq
MIRT1964111	hsa-miR-612	CLIP-seq
MIRT1964112	hsa-miR-619	CLIP-seq
MIRT1964113	hsa-miR-644	CLIP-seq
MIRT1964114	hsa-miR-650	CLIP-seq
MIRT1964115	hsa-miR-661	CLIP-seq
MIRT1964116	hsa-miR-759	CLIP-seq
MIRT1964117	hsa-miR-920	CLIP-seq
MIRT1964118	hsa-miR-922	CLIP-seq
MIRT1964119	hsa-miR-940	CLIP-seq
MIRT890872	hsa-miR-1179	CLIP-seq
MIRT1964055	hsa-miR-1207-3p	CLIP-seq
MIRT890874	hsa-miR-1236	CLIP-seq
MIRT2200250	hsa-miR-1298	CLIP-seq
MIRT890877	hsa-miR-1302	CLIP-seq
MIRT2200251	hsa-miR-1324	CLIP-seq
MIRT1964059	hsa-miR-140-5p	CLIP-seq
MIRT890878	hsa-miR-149	CLIP-seq
MIRT2200252	hsa-miR-1913	CLIP-seq
MIRT2200253	hsa-miR-203	CLIP-seq
MIRT1964064	hsa-miR-2115	CLIP-seq
MIRT2200254	hsa-miR-24	CLIP-seq
MIRT2200255	hsa-miR-25	CLIP-seq
MIRT2200256	hsa-miR-3162-3p	CLIP-seq
MIRT1964067	hsa-miR-3163	CLIP-seq
MIRT2200257	hsa-miR-3169	CLIP-seq
MIRT2200258	hsa-miR-3180-5p	CLIP-seq
MIRT1964071	hsa-miR-3192	CLIP-seq
MIRT2200259	hsa-miR-32	CLIP-seq
MIRT2200260	hsa-miR-324-3p	CLIP-seq
MIRT890885	hsa-miR-329	CLIP-seq
MIRT890887	hsa-miR-362-3p	CLIP-seq
MIRT2200261	hsa-miR-363	CLIP-seq
MIRT2200262	hsa-miR-3663-5p	CLIP-seq
MIRT2200263	hsa-miR-367	CLIP-seq
MIRT1964081	hsa-miR-3691-3p	CLIP-seq
MIRT890894	hsa-miR-3941	CLIP-seq
MIRT2200264	hsa-miR-3943	CLIP-seq
MIRT1964089	hsa-miR-4279	CLIP-seq
MIRT2200265	hsa-miR-4284	CLIP-seq
MIRT890898	hsa-miR-4298	CLIP-seq
MIRT1964091	hsa-miR-4300	CLIP-seq
MIRT1964102	hsa-miR-4531	CLIP-seq
MIRT890903	hsa-miR-4648	CLIP-seq
MIRT2200266	hsa-miR-4666-5p	CLIP-seq
MIRT2200267	hsa-miR-4668-3p	CLIP-seq
MIRT2200268	hsa-miR-4690-3p	CLIP-seq
MIRT2200269	hsa-miR-4700-3p	CLIP-seq
MIRT890909	hsa-miR-4753-3p	CLIP-seq
MIRT2200270	hsa-miR-4793-5p	CLIP-seq
MIRT2200271	hsa-miR-520a-5p	CLIP-seq
MIRT2200272	hsa-miR-525-5p	CLIP-seq
MIRT2200273	hsa-miR-568	CLIP-seq
MIRT1964110	hsa-miR-577	CLIP-seq
MIRT890919	hsa-miR-603	CLIP-seq
MIRT1964113	hsa-miR-644	CLIP-seq
MIRT1964117	hsa-miR-920	CLIP-seq
MIRT2200274	hsa-miR-92a	CLIP-seq
MIRT2200275	hsa-miR-92b	CLIP-seq
MIRT890878	hsa-miR-149	CLIP-seq
MIRT2200254	hsa-miR-24	CLIP-seq
MIRT1964068	hsa-miR-3173-3p	CLIP-seq
MIRT2200265	hsa-miR-4284	CLIP-seq
MIRT1964109	hsa-miR-4779	CLIP-seq
MIRT2200270	hsa-miR-4793-5p	CLIP-seq
MIRT890874	hsa-miR-1236	CLIP-seq
MIRT890882	hsa-miR-219-5p	CLIP-seq
MIRT890896	hsa-miR-412	CLIP-seq
MIRT890900	hsa-miR-4445	CLIP-seq
MIRT890909	hsa-miR-4753-3p	CLIP-seq
MIRT890911	hsa-miR-4768-5p	CLIP-seq
MIRT890913	hsa-miR-4782-3p	CLIP-seq
MIRT890916	hsa-miR-508-3p	CLIP-seq
MIRT1964054	hsa-miR-105	CLIP-seq
MIRT890874	hsa-miR-1236	CLIP-seq
MIRT2503102	hsa-miR-1245b-3p	CLIP-seq
MIRT2503103	hsa-miR-1280	CLIP-seq
MIRT1964058	hsa-miR-1285	CLIP-seq
MIRT890878	hsa-miR-149	CLIP-seq
MIRT1964062	hsa-miR-1827	CLIP-seq
MIRT2503104	hsa-miR-1909	CLIP-seq
MIRT2503105	hsa-miR-1915	CLIP-seq
MIRT2503106	hsa-miR-2861	CLIP-seq
MIRT2503107	hsa-miR-298	CLIP-seq
MIRT1964067	hsa-miR-3163	CLIP-seq
MIRT2503108	hsa-miR-3180	CLIP-seq
MIRT2503109	hsa-miR-3180-3p	CLIP-seq
MIRT2503110	hsa-miR-3185	CLIP-seq
MIRT1964070	hsa-miR-3187-5p	CLIP-seq
MIRT2503111	hsa-miR-3196	CLIP-seq
MIRT1964072	hsa-miR-326	CLIP-seq
MIRT1964073	hsa-miR-330-5p	CLIP-seq
MIRT1964076	hsa-miR-361-3p	CLIP-seq
MIRT1964077	hsa-miR-3614-5p	CLIP-seq
MIRT2503112	hsa-miR-3679-3p	CLIP-seq
MIRT1964083	hsa-miR-378g	CLIP-seq
MIRT2503113	hsa-miR-3921	CLIP-seq
MIRT1964087	hsa-miR-4254	CLIP-seq
MIRT2503114	hsa-miR-4260	CLIP-seq
MIRT2503115	hsa-miR-4307	CLIP-seq
MIRT2503116	hsa-miR-4308	CLIP-seq
MIRT1964095	hsa-miR-4431	CLIP-seq
MIRT2503117	hsa-miR-4434	CLIP-seq
MIRT1964099	hsa-miR-4486	CLIP-seq
MIRT2503118	hsa-miR-4516	CLIP-seq
MIRT1964101	hsa-miR-4522	CLIP-seq
MIRT1964102	hsa-miR-4531	CLIP-seq
MIRT2503119	hsa-miR-4539	CLIP-seq
MIRT1964103	hsa-miR-4640-5p	CLIP-seq
MIRT2503120	hsa-miR-4653-5p	CLIP-seq
MIRT2200266	hsa-miR-4666-5p	CLIP-seq
MIRT2503121	hsa-miR-4670-5p	CLIP-seq
MIRT2503122	hsa-miR-4709-3p	CLIP-seq
MIRT2503123	hsa-miR-4723-5p	CLIP-seq
MIRT2503124	hsa-miR-4725-5p	CLIP-seq
MIRT2503125	hsa-miR-4726-3p	CLIP-seq
MIRT1964107	hsa-miR-4726-5p	CLIP-seq
MIRT2503126	hsa-miR-4757-5p	CLIP-seq
MIRT890911	hsa-miR-4768-5p	CLIP-seq
MIRT2503127	hsa-miR-4778-5p	CLIP-seq
MIRT2503128	hsa-miR-504	CLIP-seq
MIRT2503129	hsa-miR-548ac	CLIP-seq
MIRT2503130	hsa-miR-548d-3p	CLIP-seq
MIRT2503131	hsa-miR-548z	CLIP-seq
MIRT2503132	hsa-miR-587	CLIP-seq
MIRT1964111	hsa-miR-612	CLIP-seq
MIRT1964112	hsa-miR-619	CLIP-seq
MIRT2503133	hsa-miR-885-3p	CLIP-seq
MIRT890874	hsa-miR-1236	CLIP-seq
MIRT2678130	hsa-miR-1271	CLIP-seq
MIRT2503103	hsa-miR-1280	CLIP-seq
MIRT1964058	hsa-miR-1285	CLIP-seq
MIRT2678131	hsa-miR-1292	CLIP-seq
MIRT2678132	hsa-miR-182	CLIP-seq
MIRT2503104	hsa-miR-1909	CLIP-seq
MIRT2503105	hsa-miR-1915	CLIP-seq
MIRT2503106	hsa-miR-2861	CLIP-seq
MIRT2503107	hsa-miR-298	CLIP-seq
MIRT2503108	hsa-miR-3180	CLIP-seq
MIRT2503109	hsa-miR-3180-3p	CLIP-seq
MIRT2503110	hsa-miR-3185	CLIP-seq
MIRT1964070	hsa-miR-3187-5p	CLIP-seq
MIRT2503111	hsa-miR-3196	CLIP-seq
MIRT2678133	hsa-miR-320a	CLIP-seq
MIRT2678134	hsa-miR-320b	CLIP-seq
MIRT2678135	hsa-miR-320c	CLIP-seq
MIRT2678136	hsa-miR-320d	CLIP-seq
MIRT1964072	hsa-miR-326	CLIP-seq
MIRT1964073	hsa-miR-330-5p	CLIP-seq
MIRT1964076	hsa-miR-361-3p	CLIP-seq
MIRT1964077	hsa-miR-3614-5p	CLIP-seq
MIRT2503112	hsa-miR-3679-3p	CLIP-seq
MIRT1964083	hsa-miR-378g	CLIP-seq
MIRT2503113	hsa-miR-3921	CLIP-seq
MIRT2678137	hsa-miR-3942-3p	CLIP-seq
MIRT1964087	hsa-miR-4254	CLIP-seq
MIRT2503114	hsa-miR-4260	CLIP-seq
MIRT2678138	hsa-miR-4429	CLIP-seq
MIRT1964095	hsa-miR-4431	CLIP-seq
MIRT2503117	hsa-miR-4434	CLIP-seq
MIRT2678139	hsa-miR-4470	CLIP-seq
MIRT2678140	hsa-miR-4471	CLIP-seq
MIRT2678141	hsa-miR-4481	CLIP-seq
MIRT1964099	hsa-miR-4486	CLIP-seq
MIRT2503118	hsa-miR-4516	CLIP-seq
MIRT1964101	hsa-miR-4522	CLIP-seq
MIRT1964102	hsa-miR-4531	CLIP-seq
MIRT2503119	hsa-miR-4539	CLIP-seq
MIRT1964103	hsa-miR-4640-5p	CLIP-seq
MIRT2503120	hsa-miR-4653-5p	CLIP-seq
MIRT2503121	hsa-miR-4670-5p	CLIP-seq
MIRT2503123	hsa-miR-4723-5p	CLIP-seq
MIRT2503125	hsa-miR-4726-3p	CLIP-seq
MIRT1964107	hsa-miR-4726-5p	CLIP-seq
MIRT2678142	hsa-miR-4745-5p	CLIP-seq
MIRT2503126	hsa-miR-4757-5p	CLIP-seq
MIRT2678143	hsa-miR-4762-5p	CLIP-seq
MIRT890911	hsa-miR-4768-5p	CLIP-seq
MIRT2503129	hsa-miR-548ac	CLIP-seq
MIRT2503130	hsa-miR-548d-3p	CLIP-seq
MIRT2503131	hsa-miR-548z	CLIP-seq
MIRT1964111	hsa-miR-612	CLIP-seq
MIRT1964112	hsa-miR-619	CLIP-seq
MIRT2678144	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000421	Component	Autophagosome membrane	IDA	17984323
GO:0000776	Component	Kinetochore	IDA	26040712
GO:0000776	Component	Kinetochore	IEA
GO:0000785	Component	Chromatin	IDA	28242692
GO:0000815	Component	ESCRT III complex	IBA
GO:0000815	Component	ESCRT III complex	IDA	16856878, 26040712
GO:0000815	Component	ESCRT III complex	NAS	28242692, 36107470
GO:0001778	Process	Plasma membrane repair	IDA	24482116
GO:0001778	Process	Plasma membrane repair	IEA
GO:0005515	Function	Protein binding	IPI	16856878, 28242692, 30194290, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IDA	26040712
GO:0005635	Component	Nuclear envelope	IEA
GO:0005643	Component	Nuclear pore	IDA	26040713
GO:0005643	Component	Nuclear pore	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005765	Component	Lysosomal membrane	IDA	17984323
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005771	Component	Multivesicular body	IBA
GO:0005828	Component	Kinetochore microtubule	IDA	26040712
GO:0005828	Component	Kinetochore microtubule	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	24878737
GO:0006900	Process	Vesicle budding from membrane	IBA
GO:0006914	Process	Autophagy	IMP	17984323
GO:0006997	Process	Nucleus organization	IMP	20616062
GO:0007034	Process	Vacuolar transport	IEA
GO:0007080	Process	Mitotic metaphase chromosome alignment	IEA
GO:0007080	Process	Mitotic metaphase chromosome alignment	IMP	20616062
GO:0009898	Component	Cytoplasmic side of plasma membrane	IBA
GO:0010458	Process	Exit from mitosis	IMP	26040712
GO:0015031	Process	Protein transport	IEA
GO:0030496	Component	Midbody	IDA	26040712
GO:0030496	Component	Midbody	IEA
GO:0031468	Process	Nuclear membrane reassembly	IEA
GO:0031468	Process	Nuclear membrane reassembly	IMP	26040712, 26040713
GO:0031468	Process	Nuclear membrane reassembly	TAS	28242692
GO:0032511	Process	Late endosome to vacuole transport via multivesicular body sorting pathway	IBA
GO:0032585	Component	Multivesicular body membrane	IDA	16554368
GO:0032585	Component	Multivesicular body membrane	IEA
GO:0036258	Process	Multivesicular body assembly	NAS	16505166, 20588296
GO:0039702	Process	Viral budding via host ESCRT complex	IDA	24878737
GO:0039702	Process	Viral budding via host ESCRT complex	IEA
GO:0039702	Process	Viral budding via host ESCRT complex	NAS	20588296
GO:0043162	Process	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IDA	17984323
GO:0043162	Process	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IEA
GO:0045324	Process	Late endosome to vacuole transport	IMP	16856878
GO:0046761	Process	Viral budding from plasma membrane	IDA	24878737
GO:0046761	Process	Viral budding from plasma membrane	IEA
GO:0051469	Process	Vesicle fusion with vacuole	NAS	16505166
GO:0061763	Process	Multivesicular body-lysosome fusion	NAS	16505166
GO:0061952	Process	Midbody abscission	IEA
GO:0061952	Process	Midbody abscission	IMP	20616062
GO:0071168	Process	Protein localization to chromatin	IMP	28242692
GO:0071985	Process	Multivesicular body sorting pathway	IDA	16554368
GO:0071985	Process	Multivesicular body sorting pathway	IEA
GO:0090148	Process	Membrane fission	NAS	19234443
GO:0097352	Process	Autophagosome maturation	IEA
GO:0097352	Process	Autophagosome maturation	IMP	17984323
GO:1901673	Process	Regulation of mitotic spindle assembly	IEA
GO:1901673	Process	Regulation of mitotic spindle assembly	IMP	20616062
GO:1902774	Process	Late endosome to lysosome transport	IEA
GO:1902774	Process	Late endosome to lysosome transport	IMP	17984323
GO:1904903	Process	ESCRT III complex disassembly	NAS	20588296
GO:1904930	Component	Amphisome membrane	IDA	17984323
GO:1904930	Component	Amphisome membrane	IEA

Other IDs

• MIM: 611130
• HGNC: 28439
• e!Ensembl: ENSG00000147457

Protein

• UniProt ID: Q8WUX9
• Protein name: Charged multivesicular body protein 7 (Chromatin-modifying protein 7)
• Protein function: ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase (PubMed:26040712). Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anap
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03357	Snf7	241 → 443	Snf7	Family

• Sequence:

  MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLV
  LSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWIS
  WGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVAL
  SELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVG
  VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHA
  KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE
  VSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAE
  LEAELEKLSLSEGGLVPSSKSPKRQLEPTLKPL

• Sequence length: 453

Pathways

KEGG:

Virion - Hepatitis viruses
Endocytosis
Necroptosis

Reactome:

Budding and maturation of HIV virion
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Sealing of the nuclear envelope (NE) by ESCRT-III

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Amyotrophic Lateral Sclerosis	Amyotrophic lateral sclerosis	Pubtator	39486415	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	34321318	Associate	★☆☆☆☆ Found in Text Mining only
Liver Neoplasms	Liver neoplasm	Pubtator	34281622, 34321318	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	37194062	Associate	★☆☆☆☆ Found in Text Mining only