Gene Gene information from NCBI Gene database.
Entrez ID 9168
Gene name Thymosin beta 10
Gene symbol TMSB10
Synonyms (NCBI Gene)
MIG12TB10
Chromosome 2
Chromosome location 2p11.2
miRNA miRNA information provided by mirtarbase database.
484
miRTarBase ID miRNA Experiments Reference
MIRT051009 hsa-miR-17-5p CLASH 23622248
MIRT040459 hsa-miR-615-3p CLASH 23622248
MIRT038714 hsa-miR-101-5p CLASH 23622248
MIRT726271 hsa-miR-27a-3p HITS-CLIP 22473208
MIRT726270 hsa-miR-27b-3p HITS-CLIP 22473208
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0003779 Function Actin binding IEA
GO:0003785 Function Actin monomer binding IBA
GO:0003785 Function Actin monomer binding IEA
GO:0005515 Function Protein binding IPI 21044950, 25416956, 32296183
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
188399 11879 ENSG00000034510
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P63313
Protein name Thymosin beta-10
Protein function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01290 Thymosin 3 41 Thymosin beta-4 family Family
Sequence
Sequence length 44
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
BIPOLAR DISORDER Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
DERMATITIS, ALLERGIC CONTACT CTD, Disgenet
CTD, Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Adenocarcinoma Adenocarcinoma BEFREE 22038593
★☆☆☆☆
Found in Text Mining only
Alzheimer Disease Alzheimer disease Pubtator 37348871 Associate
★☆☆☆☆
Found in Text Mining only
Anaplastic carcinoma Anaplastic Carcinoma BEFREE 12324571, 9485041
★☆☆☆☆
Found in Text Mining only
Arteriosclerosis Arteriosclerosis BEFREE 11156961
★☆☆☆☆
Found in Text Mining only
Atherosclerosis Atherosclerosis BEFREE 11156961
★☆☆☆☆
Found in Text Mining only
Bipolar Disorder Bipolar Disorder PSYGENET_DG 22675524
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Bipolar Disorder Bipolar disorder Pubtator 22675524 Inhibit
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Bladder Neoplasm Bladder Neoplasm BEFREE 31616507
★☆☆☆☆
Found in Text Mining only
Brain Neoplasms Brain neoplasms Pubtator 35328618 Associate
★☆☆☆☆
Found in Text Mining only
Breast Carcinoma Breast Carcinoma BEFREE 28179017
★☆☆☆☆
Found in Text Mining only